Metabolism of methylstenbolone studied with human liver microsomes and the uPA+/+-SCID chimeric mouse model

Biomedical Chromatography

Volumn 28, Issue 7, 2014, Pages 974-985

  Geldof, Lore ^a   Lootens, Leen ^a   Polet, Michael ^a   Eichner, Daniel ^b   Campbell, Thane ^b   Nair, Vinod ^b   Botrè, Francesco ^c   Meuleman, Philip ^d   Leroux Roels, Geert ^d   Deventer, Koen ^a   Eenoo, Peter Van ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Sports Medicine Research and Testing Laboratory   (United States)

^c Laboratorio Antidoping Federazione Medico Sportiva Italiana (FMSI)   (Italy)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

GC MS; in vitro and in vivo studies; LC MS; Phase I metabolism; Steroids

Indexed keywords

BIOMOLECULES; HYDROXYLATION; MAMMALS; METABOLITES; PHYSIOLOGY;

GC-MS; HUMAN LIVER MICROSOMES; IN VITRO AND IN VIVO STUDY; IN-VITRO; LC-MS; MICE MODELS; PHASE I; PHASE I METABOLISM; STEROID; VITRO AND IN VIVO STUDIES;

METABOLISM;

STEROID; 2,17-DIMETHYL-17-HYDROXYANDROST-1-EN-3-ONE; ANDROSTANE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMERA; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; MASS SPECTROMETRY; MOUSE; NONHUMAN; STEROID HYDROXYLATION; STEROID URINE LEVEL; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; MASS FRAGMENTOGRAPHY; METABOLISM; PROCEDURES; SCID MOUSE; TANDEM MASS SPECTROMETRY; TRANSGENIC MOUSE; URINE;

ANDROSTENOLS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MICE; MICE, SCID; MICE, TRANSGENIC; MICROSOMES, LIVER; MODELS, MOLECULAR; TANDEM MASS SPECTROMETRY;

EID: 84902538061     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3105     Document Type: Article

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