The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation

Journal of Biological Chemistry

Volumn 289, Issue 24, 2014, Pages 17054-17069

  Moskot, Marta ^a   Montefusco, Sandro ^b   Jakóbkiewicz Banecka, Joanna ^c   Mozolewski, Paweł ^c   Wȩgrzyn, Alicja ^d   Di Bernardo, Diego ^b   Wȩgrzyn, Grzegorz ^c   Medina, Diego L ^b   Ballabio, Andrea ^b,e,f,g   Gabig Cimińska, Magdalena ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^c UNIVERSITY OF GDA SK   (Poland)

^d UNIVERSITY OF SZCZECIN   (Poland)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f TEXAS CHILDREN S HOSPITAL   (United States)

^g UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CHEMICAL ACTIVATION; DIGITAL STORAGE; DISEASE CONTROL; DRUG THERAPY; GENES; METABOLISM; PHYSIOLOGY; TRANSCRIPTION FACTORS;

BLOOD-BRAIN BARRIER; DEGRADATION PATHWAYS; GLYCOSAMINOGLYCANS; LYSOSOMAL BIOGENESIS; MOLECULAR MECHANISM; NEUROLOGICAL SYMPTOMS; NUCLEAR TRANSLOCATIONS; REGULATORY NETWORK;

FLAVONOIDS;

GENISTIN; GLYCOSAMINOGLYCAN; PHYTOESTROGEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CELL FUNCTION; CELL METABOLISM; CELL NUCLEUS; CONTROLLED STUDY; EMBRYO; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE PRODUCT; GENE REGULATORY NETWORK; GLYCOSAMINOGLYCAN METABOLISM; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LYSOSOME; METABOLIC REGULATION; MOLECULAR GENETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TRANSPORT; TRANSCRIPTION FACTOR EB GENE; TRANSCRIPTION INITIATION;

FLAVONOID; GENE EXPRESSION; GENISTEIN; LYSOSOMAL METABOLISM; LYSOSOMAL STORAGE DISEASE; MICROARRAY; NEURODEGENERATIVE DISEASE; SUBSTRATE REDUCTION THERAPY; TRANSCRIPTOMIC NETWORK ANALYSIS; TRANSCRIPTOMICS;

ACTIVE TRANSPORT, CELL NUCLEUS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE; GENE REGULATORY NETWORKS; GENISTEIN; GLYCOSAMINOGLYCANS; HUMANS; LYSOSOMES; PHYTOESTROGENS; TRANSCRIPTION, GENETIC;

EID: 84902531880     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.555300     Document Type: Article

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