-
1
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
Akiyama T, Ishida J, Nakagawa S, Ogawara H,Watanabe S, Itoh N et al. (1987). Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595.
-
(1987)
J Biol Chem
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.5
Itoh, N.6
-
2
-
-
40949095655
-
Guide to Receptors and Channels (GRAC)
-
3rd Edition
-
Alexander SP, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd Edition. Br J Pharmacol 153 (Suppl. 2): S1-S209.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 2
-
-
Alexander, S.P.1
Mathie, A.2
Peters, J.A.3
-
3
-
-
38449110954
-
Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier
-
Boado RJ, Zhang Y, Zhang Y, Xia CF, Wang Y, Pardridge WM (2008). Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier. Biotechnol Bioeng 99: 475-484.
-
(2008)
Biotechnol Bioeng
, vol.99
, pp. 475-484
-
-
Boado, R.J.1
Zhang, Y.2
Zhang, Y.3
Xia, C.F.4
Wang, Y.5
Pardridge, W.M.6
-
4
-
-
67650227488
-
The epidermal growth factor receptor: A link between inflammation and liver cancer
-
Berasain C, Perugorria MJ, Latasa MU, Castillo J, Goñi S, Santamaria M et al. (2009). The epidermal growth factor receptor: a link between inflammation and liver cancer. Exp Biol Med 234: 713-725.
-
(2009)
Exp Biol Med
, vol.234
, pp. 713-725
-
-
Berasain, C.1
Perugorria, M.J.2
Latasa, M.U.3
Castillo, J.4
Goñi, S.5
Santamaria, M.6
-
5
-
-
0027300720
-
Simultaneous preparation and quantitation of proteoglycans by precipitation with alcian blue
-
Bjornsson S (1993). Simultaneous preparation and quantitation of proteoglycans by precipitation with alcian blue. Anal Biochem 210: 282-291.
-
(1993)
Anal Biochem
, vol.210
, pp. 282-291
-
-
Bjornsson, S.1
-
6
-
-
33645110474
-
Correction of Hunter syndrome in the MPSII mouse model by AAV2/8-mediated gene delivery
-
Cardone M, Polito VA, Pepe S, Mann L, D'Azzo A, Auricchio A et al. (2006). Correction of Hunter syndrome in the MPSII mouse model by AAV2/8-mediated gene delivery. Hum Mol Genet 15: 1225-1236.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1225-1236
-
-
Cardone, M.1
Polito, V.A.2
Pepe, S.3
Mann, L.4
D'Azzo, A.5
Auricchio, A.6
-
7
-
-
67649369606
-
Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: A 2-year randomized, double-blind, placebocontrolled study
-
D'Anna R, Cannata ML, Marini H, Atteritano M, Cancellieri F, Corrado F et al. (2009). Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 2-year randomized, double-blind, placebocontrolled study. Menopause 16: 320-328.
-
(2009)
Menopause
, vol.16
, pp. 320-328
-
-
D'Anna, R.1
Cannata, M.L.2
Marini, H.3
Atteritano, M.4
Cancellieri, F.5
Corrado, F.6
-
9
-
-
33748076106
-
Positive effect of dietary soy in ESRD patients with systemic inflammation - correlation between blood levels of the soy isoflavones and the acute-phase reactants
-
Fanti P, Asmis R, Stephenson TJ, Sawaya BP, Franke AA (2006). Positive effect of dietary soy in ESRD patients with systemic inflammation - correlation between blood levels of the soy isoflavones and the acute-phase reactants. Nephrol Dial Transplant 21: 2239-2246.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 2239-2246
-
-
Fanti, P.1
Asmis, R.2
Stephenson, T.J.3
Sawaya, B.P.4
Franke, A.A.5
-
10
-
-
3843151539
-
Clinical characteristics and pharmacokinetics of purified soy isoflavones: Multiple-dose administration to men with prostate neoplasia
-
Fischer L, Mahoney C, Jeffcoat AR, Koch MA, Thomas BE, Valentine JL et al. (2004). Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutr Cancer 48: 160-170.
-
(2004)
Nutr Cancer
, vol.48
, pp. 160-170
-
-
Fischer, L.1
Mahoney, C.2
Jeffcoat, A.R.3
Koch, M.A.4
Thomas, B.E.5
Valentine, J.L.6
-
11
-
-
27944473627
-
Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts
-
Friso A, Tomanin R, Alba S, Gasparotto N, Puicher EP, Fusco M et al. (2005). Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts. J Gene Med 7: 1482-1491.
-
(2005)
J Gene Med
, vol.7
, pp. 1482-1491
-
-
Friso, A.1
Tomanin, R.2
Alba, S.3
Gasparotto, N.4
Puicher, E.P.5
Fusco, M.6
-
12
-
-
52049124536
-
Gene therapy of Hunter syndrome: Evaluation of the efficiency of muscle electro gene transfer for the production and release of recombinant iduronate-2-sulfatase (IDS)
-
Friso A, Tomanin R, Zanetti A, Mennuni C, Calvaruso F, La Monica N et al. (2008). Gene therapy of Hunter syndrome: evaluation of the efficiency of muscle electro gene transfer for the production and release of recombinant iduronate-2-sulfatase (IDS). Biochim Biophys Acta 1782: 574-580.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 574-580
-
-
Friso, A.1
Tomanin, R.2
Zanetti, A.3
Mennuni, C.4
Calvaruso, F.5
La Monica, N.6
-
13
-
-
34447098114
-
Significantly increased lifespan and improved behavioral performances by rAAV gene delivery in adult mucopolysaccharidosis IIIB mice
-
Fu H, Kang L, Jennings JS, Moy SS, Perez A, DiRosario J et al. (2007). Significantly increased lifespan and improved behavioral performances by rAAV gene delivery in adult mucopolysaccharidosis IIIB mice. Gene Ther 14: 1065-1077.
-
(2007)
Gene Ther
, vol.14
, pp. 1065-1077
-
-
Fu, H.1
Kang, L.2
Jennings, J.S.3
Moy, S.S.4
Perez, A.5
DiRosario, J.6
-
14
-
-
37249043762
-
The characterization of a murine model of mucopolysaccharidosis II (Hunter syndrome)
-
Garcia AR, Pan J, Lamsa JC, Muenzer J (2007). The characterization of a murine model of mucopolysaccharidosis II (Hunter syndrome). J Inherit Metab Dis 30: 924-934.
-
(2007)
J Inherit Metab Dis
, vol.30
, pp. 924-934
-
-
Garcia, A.R.1
Pan, J.2
Lamsa, J.C.3
Muenzer, J.4
-
15
-
-
31344441221
-
Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
-
Gu Y, Zhu CF, Iwamoto H, Chen JS (2005). Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J Gastroenterol 11: 6512-6517.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 6512-6517
-
-
Gu, Y.1
Zhu, C.F.2
Iwamoto, H.3
Chen, J.S.4
-
16
-
-
63449130617
-
Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway
-
Jakobkiewicz-Banecka J, Piotrowska E, Narajczyk M, Baranska S, Wegrzyn G (2009). Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway. J Biomed Sci 16: 26.
-
(2009)
J Biomed Sci
, vol.16
, pp. 26
-
-
Jakobkiewicz-Banecka, J.1
Piotrowska, E.2
Narajczyk, M.3
Baranska, S.4
Wegrzyn, G.5
-
17
-
-
0026872139
-
Measuring urinary glycosaminoglycans in the presence of protein: An improved screening procedure for mucopolysaccharidoses based on dimethylmethylene blue
-
de Jong JG, Wevers RA, Liebrand-van Sambeek R (1992). Measuring urinary glycosaminoglycans in the presence of protein: an improved screening procedure for mucopolysaccharidoses based on dimethylmethylene blue. Clin Chem 38: 803-807.
-
(1992)
Clin Chem
, vol.38
, pp. 803-807
-
-
de Jong, J.G.1
Wevers, R.A.2
Liebrand-van Sambeek, R.3
-
18
-
-
0031741785
-
Mechanisms of action of the soy isoflavone genistein: Emerging role for its effects via transforming growth factor beta signaling pathways
-
Kim H, Peterson TG, Barnes S (1998). Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways. Am J Clin Nutr 68: 1418S-1425S.
-
(1998)
Am J Clin Nutr
, vol.68
-
-
Kim, H.1
Peterson, T.G.2
Barnes, S.3
-
19
-
-
38649088871
-
Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease
-
Liu LX, Chen WF, Xie JX, Wong MS (2008). Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease. Neurosci Res 60: 156-161.
-
(2008)
Neurosci Res
, vol.60
, pp. 156-161
-
-
Liu, L.X.1
Chen, W.F.2
Xie, J.X.3
Wong, M.S.4
-
20
-
-
21844441386
-
Subchronic and chronic safety studies with genistein in dogs
-
McClain RM, Wolz E, Davidovich A, Pfannkuch F, Bausch J (2005). Subchronic and chronic safety studies with genistein in dogs. Food Chem Toxicol 43: 1461-1482.
-
(2005)
Food Chem Toxicol
, vol.43
, pp. 1461-1482
-
-
McClain, R.M.1
Wolz, E.2
Davidovich, A.3
Pfannkuch, F.4
Bausch, J.5
-
21
-
-
28844496719
-
Acute, subchronic and chronic safety studies with genistein in rats
-
McClain RM, Wolz E, Davidovich A, Pfannkuch F, Edwards JA, Bausch J (2006). Acute, subchronic and chronic safety studies with genistein in rats. Food Chem Toxicol 44: 56-80.
-
(2006)
Food Chem Toxicol
, vol.44
, pp. 56-80
-
-
McClain, R.M.1
Wolz, E.2
Davidovich, A.3
Pfannkuch, F.4
Edwards, J.A.5
Bausch, J.6
-
22
-
-
0037392352
-
Lack of significant toxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer
-
Myltic W, Craciunescu CN, Fischer L, Jeffcoat RA, Koch MA, Lopaczynski W et al. (2003). Lack of significant toxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. Am J Clin Nutr 77: 875-882.
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 875-882
-
-
Myltic, W.1
Craciunescu, C.N.2
Fischer, L.3
Jeffcoat, R.A.4
Koch, M.A.5
Lopaczynski, W.6
-
23
-
-
0000869162
-
The mucopolysaccharidoses
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Childs R, Kinzler KW eds, McGraw-Hill Professional Publishing: New York, pp
-
Neufeld EF, Muenzer J (2001). The mucopolysaccharidoses. In: Scriver CR, Beaudet AL, Sly WS, Valle D, Childs R, Kinzler KW (eds). The Metabolic and Molecular Bases of Inherited Disease. McGraw-Hill Professional Publishing: New York, pp. 3421-3452.
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 3421-3452
-
-
Neufeld, E.F.1
Muenzer, J.2
-
24
-
-
0037233849
-
The effects of genistein on the synthesis and distribution of glycosaminoglycans/ proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density
-
Nikitovic D, Tsatsakis AM, Karamanos NK, Tzanakakis GN (2003). The effects of genistein on the synthesis and distribution of glycosaminoglycans/ proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density. Anticancer Res 23: 459-464.
-
(2003)
Anticancer Res
, vol.23
, pp. 459-464
-
-
Nikitovic, D.1
Tsatsakis, A.M.2
Karamanos, N.K.3
Tzanakakis, G.N.4
-
25
-
-
0031016446
-
Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain
-
Penar PL, Khoshyomn S, Bhushan A, Tritton TR (1997). Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain. Neurosurgery 40: 141-151.
-
(1997)
Neurosurgery
, vol.40
, pp. 141-151
-
-
Penar, P.L.1
Khoshyomn, S.2
Bhushan, A.3
Tritton, T.R.4
-
26
-
-
33745279635
-
Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expressiontargeted isoflavone therapy for mucopolysaccharidoses
-
Piotrowska E, Jakobkiewicz-Banecka J, Baranska S, Tylki-Szymanska A, Czartoryska B, Wegrzyn A et al. (2006). Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expressiontargeted isoflavone therapy for mucopolysaccharidoses. Eur J Hum Genet 14: 846-852.
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 846-852
-
-
Piotrowska, E.1
Jakobkiewicz-Banecka, J.2
Baranska, S.3
Tylki-Szymanska, A.4
Czartoryska, B.5
Wegrzyn, A.6
-
27
-
-
45149107757
-
Genistin-rich soy isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: An open-label, pilot study in 10 pediatric patients
-
Piotrowska E, Jakóbkiewicz-Banecka J, Tylki-Szymanska A, Liberek A, Maryniak A, Malinowska M et al. (2008). Genistin-rich soy isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: An open-label, pilot study in 10 pediatric patients. Curr Ther Res Clin Exp 69: 166-179.
-
(2008)
Curr Ther Res Clin Exp
, vol.69
, pp. 166-179
-
-
Piotrowska, E.1
Jakóbkiewicz-Banecka, J.2
Tylki-Szymanska, A.3
Liberek, A.4
Maryniak, A.5
Malinowska, M.6
-
28
-
-
0023265039
-
Epidermal growth factor potentiates the induction of ornithine decarboxylase activity by prostaglandins in embryonic palate mesenchymal cells: Effects on cell proliferation and glycosaminoglycan synthesis
-
Pisano MM, Greene RM (1987). Epidermal growth factor potentiates the induction of ornithine decarboxylase activity by prostaglandins in embryonic palate mesenchymal cells: effects on cell proliferation and glycosaminoglycan synthesis. Dev Biol 122: 419-431.
-
(1987)
Dev Biol
, vol.122
, pp. 419-431
-
-
Pisano, M.M.1
Greene, R.M.2
-
29
-
-
33747610195
-
Inhibition of glycosaminoglycan synthesis using rhodamine B in a mouse model of mucopolysaccharidosis type IIIA
-
Roberts AL, Thomas BJ, Wilkinson AS, Fletcher JM, Byers S (2006). Inhibition of glycosaminoglycan synthesis using rhodamine B in a mouse model of mucopolysaccharidosis type IIIA. Pediatr Res 60: 309-314.
-
(2006)
Pediatr Res
, vol.60
, pp. 309-314
-
-
Roberts, A.L.1
Thomas, B.J.2
Wilkinson, A.S.3
Fletcher, J.M.4
Byers, S.5
-
30
-
-
34548411851
-
Improvement in behaviour after substrate deprivation therapy with rhodamine B in a mouse model of MPS IIIA
-
Roberts AL, Rees MH, Klebe S, Fletcher JM, Byers S (2007). Improvement in behaviour after substrate deprivation therapy with rhodamine B in a mouse model of MPS IIIA. Mol Genet Metab 92: 115-121.
-
(2007)
Mol Genet Metab
, vol.92
, pp. 115-121
-
-
Roberts, A.L.1
Rees, M.H.2
Klebe, S.3
Fletcher, J.M.4
Byers, S.5
-
31
-
-
0031047057
-
Hyaluronan synthesis by mouse cumulus cells is regulated by interactions between follicle-stimulating hormone (or epidermal growth factor) and a soluble oocyte factor (or transforming growth factor beta1)
-
Tirone E, D'Alessandris C, Hascall VC, Siracusa G, Salustri A (1997). Hyaluronan synthesis by mouse cumulus cells is regulated by interactions between follicle-stimulating hormone (or epidermal growth factor) and a soluble oocyte factor (or transforming growth factor beta1). J Biol Chem 272: 4787-4794.
-
(1997)
J Biol Chem
, vol.272
, pp. 4787-4794
-
-
Tirone, E.1
D'Alessandris, C.2
Hascall, V.C.3
Siracusa, G.4
Salustri, A.5
-
32
-
-
40549120620
-
Enzyme replacement therapy in a murine model of Morquio A syndrome
-
Tomatsu S, Montaño AM, Ohashi A, Gutierres MA, Oikawa H, Oguma T et al. (2007). Enzyme replacement therapy in a murine model of Morquio A syndrome. Hum Mol Genet 17: 815-824.
-
(2007)
Hum Mol Genet
, vol.17
, pp. 815-824
-
-
Tomatsu, S.1
Montaño, A.M.2
Ohashi, A.3
Gutierres, M.A.4
Oikawa, H.5
Oguma, T.6
-
33
-
-
17444409704
-
Concurrent measurement of unbound genistein in the blood, brain and bile of anesthetized rats using microdialysis and its pharmacokinetic application
-
Tsai TH (2005). Concurrent measurement of unbound genistein in the blood, brain and bile of anesthetized rats using microdialysis and its pharmacokinetic application. J Chromatogr A 1073: 317-322.
-
(2005)
J Chromatogr A
, vol.1073
, pp. 317-322
-
-
Tsai, T.H.1
-
34
-
-
4344630950
-
Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier
-
Urayama A, Grubb JH, Sly WS, Banks WA (2004). Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier. Proc Natl Acad Sci USA 101: 12658-12663.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12658-12663
-
-
Urayama, A.1
Grubb, J.H.2
Sly, W.S.3
Banks, W.A.4
-
35
-
-
34547896622
-
Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor
-
Urayama A, Grubb JH, Banks WA, Sly WS (2007). Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor. Proc Natl Acad Sci USA 104: 12873-12878.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12873-12878
-
-
Urayama, A.1
Grubb, J.H.2
Banks, W.A.3
Sly, W.S.4
-
36
-
-
45749090515
-
Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse
-
Urayama A, Grubb JH, Sly WS, Banks WA (2008). Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse. Mol Ther 16: 1261-1266.
-
(2008)
Mol Ther
, vol.16
, pp. 1261-1266
-
-
Urayama, A.1
Grubb, J.H.2
Sly, W.S.3
Banks, W.A.4
-
37
-
-
33846990867
-
Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: Involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity
-
Vera R, Sanchez M, Galisteo M, Villar IC, Jimenez R, Zarzuelo A et al. (2007). Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity. Clin Sci (Lond) 112: 183-191.
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 183-191
-
-
Vera, R.1
Sanchez, M.2
Galisteo, M.3
Villar, I.C.4
Jimenez, R.5
Zarzuelo, A.6
-
38
-
-
26844534412
-
Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII
-
Vogler C, Levy B, Grubb JH, Galvin N, Tan Y, Kakkis E et al. (2005). Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII. Proc Natl Acad Sci USA 102: 14777-14782.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14777-14782
-
-
Vogler, C.1
Levy, B.2
Grubb, J.H.3
Galvin, N.4
Tan, Y.5
Kakkis, E.6
-
39
-
-
33750524252
-
Pharmacological studies of the large-scaled purified genistein from Huaijiao (Sophora japonica-Leguminosae) on anti-osteoporosis
-
Wang ZL, Sun JY, Wang DN, Xie YH, Wang SW, Zhao WM (2006). Pharmacological studies of the large-scaled purified genistein from Huaijiao (Sophora japonica-Leguminosae) on anti-osteoporosis. Phytomedicine 13: 718-723.
-
(2006)
Phytomedicine
, vol.13
, pp. 718-723
-
-
Wang, Z.L.1
Sun, J.Y.2
Wang, D.N.3
Xie, Y.H.4
Wang, S.W.5
Zhao, W.M.6
|