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Volumn 289, Issue 24, 2014, Pages 17132-17141

Expression of the yeast cation diffusion facilitators Mmt1 and Mmt2 affects mitochondrial and cellular iron homeostasis: Evidence for mitochondrial iron export

Author keywords

[No Author keywords available]

Indexed keywords

ENCODING (SYMBOLS); GENES; MITOCHONDRIA; PHYSIOLOGY; POSITIVE IONS; YEAST;

EID: 84902531876     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.574723     Document Type: Article
Times cited : (29)

References (30)
  • 1
    • 0037025331 scopus 로고    scopus 로고
    • Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
    • DOI 10.1074/jbc.M111789200
    • Foury, F., and Roganti, T. (2002) Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J. Biol. Chem. 277, 24475-24483 (Pubitemid 34951972)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.27 , pp. 24475-24483
    • Foury, F.1    Roganti, T.2
  • 3
    • 4043084194 scopus 로고    scopus 로고
    • A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism
    • DOI 10.1074/jbc.M403146200
    • Li, L., and Kaplan, J. (2004) A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. J. Biol. Chem. 279, 33653-33661 (Pubitemid 39063015)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.32 , pp. 33653-33661
    • Li, L.1    Kaplan, J.2
  • 4
    • 21244448393 scopus 로고    scopus 로고
    • Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis
    • DOI 10.1074/jbc.M500397200
    • Zhang, Y., Lyver, E. R., Knight, S. A., Lesuisse, E., and Dancis, A. (2005) Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis. J. Biol. Chem. 280, 19794-19807 (Pubitemid 41379505)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.20 , pp. 19794-19807
    • Zhang, Y.1    Lyver, E.K.2    Knight, S.A.B.3    Lesuisse, E.4    Dancis, A.5
  • 6
    • 77953655166 scopus 로고    scopus 로고
    • Drosophila mitoferrin is essential for male fertility: Evidence for a role of mitochondrial iron metabolism during spermatogenesis
    • Metzendorf, C., and Lind, M. I. (2010) Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis. BMC Dev. Biol. 10, 68-84
    • (2010) BMC Dev. Biol. , vol.10 , pp. 68-84
    • Metzendorf, C.1    Lind, M.I.2
  • 9
    • 77951235682 scopus 로고    scopus 로고
    • Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport
    • Li, L., Murdock, G., Bagley, D., Jia, X., Ward, D. M., and Kaplan, J. (2010) Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport. J. Biol. Chem. 285, 10232-10242
    • (2010) J. Biol. Chem. , vol.285 , pp. 10232-10242
    • Li, L.1    Murdock, G.2    Bagley, D.3    Jia, X.4    Ward, D.M.5    Kaplan, J.6
  • 10
    • 80054934927 scopus 로고    scopus 로고
    • Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria
    • Yoon, H., Zhang, Y., Pain, J., Lyver, E. R., Lesuisse, E., Pain, D., and Dancis, A. (2011) Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria. Biochem. J. 440, 137-146
    • (2011) Biochem. J. , vol.440 , pp. 137-146
    • Yoon, H.1    Zhang, Y.2    Pain, J.3    Lyver, E.R.4    Lesuisse, E.5    Pain, D.6    Dancis, A.7
  • 11
    • 30744433627 scopus 로고    scopus 로고
    • Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: Bacterial expression, reconstitution and functional characterization
    • DOI 10.1042/BJ20051284
    • Marobbio, C. M., Di Noia, M. A., and Palmieri, F. (2006) Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization. Biochem. J. 393, 441-446 (Pubitemid 43099083)
    • (2006) Biochemical Journal , vol.393 , Issue.2 , pp. 441-446
    • Marobbio, C.M.T.1    Di, N.M.A.2    Palmieri, F.3
  • 12
    • 0035800856 scopus 로고    scopus 로고
    • CCC1 is a transporter that mediates vacuolar iron storage in yeast
    • Li, L., Chen, O. S., McVey Ward, D., and Kaplan, J. (2001) CCC1 is a transporter that mediates vacuolar iron storage in yeast. J. Biol. Chem. 276, 29515-29519
    • (2001) J. Biol. Chem. , vol.276 , pp. 29515-29519
    • Li, L.1    Chen, O.S.2    McVey Ward, D.3    Kaplan, J.4
  • 13
    • 79952779937 scopus 로고    scopus 로고
    • Genetic and biochemical analysis of high iron toxicity in yeast: Iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions
    • Lin, H., Li, L., Jia, X., Ward, D. M., and Kaplan, J. (2011) Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions. J. Biol. Chem. 286, 3851-3862
    • (2011) J. Biol. Chem. , vol.286 , pp. 3851-3862
    • Lin, H.1    Li, L.2    Jia, X.3    Ward, D.M.4    Kaplan, J.5
  • 15
    • 0033565665 scopus 로고    scopus 로고
    • The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins
    • DOI 10.1093/emboj/18.14.3981
    • Kispal, G., Csere, P., Prohl, C., and Lill, R. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J. 18, 3981-3989 (Pubitemid 29335851)
    • (1999) EMBO Journal , vol.18 , Issue.14 , pp. 3981-3989
    • Kispal, G.1    Csere, P.2    Prohl, C.3    Lill, R.4
  • 16
    • 81755189079 scopus 로고    scopus 로고
    • Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner
    • Bedekovics, T., Li, H., Gajdos, G. B., and Isaya, G. (2011) Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. J. Biol. Chem. 286, 40878-40888
    • (2011) J. Biol. Chem. , vol.286 , pp. 40878-40888
    • Bedekovics, T.1    Li, H.2    Gajdos, G.B.3    Isaya, G.4
  • 18
    • 0030662261 scopus 로고    scopus 로고
    • Characterization of two homologous yeast genes that encode mitochondrial iron transporters
    • DOI 10.1074/jbc.272.45.28485
    • Li, L., and Kaplan, J. (1997) Characterization of two homologous yeast genes that encode mitochondrial iron transporters, J. Biol. Chem. 272, 28485-28493 (Pubitemid 27517797)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.45 , pp. 28485-28493
    • Li, L.1    Kaplan, J.2
  • 19
    • 84867415067 scopus 로고    scopus 로고
    • A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast
    • Li, L., Miao, R., Bertram, S., Jia, X., Ward, D. M., and Kaplan, J. (2012) A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast. J. Biol. Chem. 287, 35709-35721
    • (2012) J. Biol. Chem. , vol.287 , pp. 35709-35721
    • Li, L.1    Miao, R.2    Bertram, S.3    Jia, X.4    Ward, D.M.5    Kaplan, J.6
  • 20
    • 0031980266 scopus 로고    scopus 로고
    • Dietary iron intake rapidly influences iron regulatory proteins, ferritin subunits and mitochondrial aconitase in rat liver
    • Chen, O. S., Blemings, K. P., Schalinske, K. L., and Eisenstein, R. S. (1998) Dietary iron intake rapidly influences iron regulatory proteins, ferritin subunits and mitochondrial aconitase in rat liver. J. Nutr. 128, 525-535 (Pubitemid 28188348)
    • (1998) Journal of Nutrition , vol.128 , Issue.3 , pp. 525-535
    • Chen, O.S.1    Blemings, K.P.2    Schalinske, K.L.3    Eisenstein, R.S.4
  • 21
    • 0037131163 scopus 로고    scopus 로고
    • The yeast iron regulon is induced upon cobalt stress and crucial for cobalt tolerance
    • DOI 10.1074/jbc.M203924200
    • Stadler, J. A., and Schweyen, R. J. (2002) The yeast iron regulon is induced upon cobalt stress and crucial for cobalt tolerance. J. Biol. Chem. 277, 39649-39654 (Pubitemid 35190946)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.42 , pp. 39649-39654
    • Stadler, J.A.1    Schweyen, R.J.2
  • 22
    • 84891933594 scopus 로고    scopus 로고
    • Cellular iron homeostasis mediated by the Mrs4-Ccc1-Smf3 pathway is essential for mitochondrial function, morphogenesis and virulence in Candida albicans
    • Xu, N., Dong, Y., Cheng, X., Yu, Q., Qian, K., Mao, J., Jia, C., Ding, X., Zhang, B., Chen, Y., Zhang, B., Xing, L., and Li, M. (2014) Cellular iron homeostasis mediated by the Mrs4-Ccc1-Smf3 pathway is essential for mitochondrial function, morphogenesis and virulence in Candida albicans. Biochim. Biophys. Acta 1843, 629-639
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 629-639
    • Xu, N.1    Dong, Y.2    Cheng, X.3    Yu, Q.4    Qian, K.5    Mao, J.6    Jia, C.7    Ding, X.8    Zhang, B.9    Chen, Y.10    Zhang, B.11    Xing, L.12    Li, M.13
  • 23
    • 44849098197 scopus 로고    scopus 로고
    • Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis
    • Kumánovics, A., Chen, O. S., Li, L., Bagley, D., Adkins, E. M., Lin, H., Dingra, N. N., Outten, C. E., Keller, G., Winge, D., Ward, D. M., and Kaplan, J. (2008) Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis. J. Biol. Chem. 283, 10276-10286
    • (2008) J. Biol. Chem. , vol.283 , pp. 10276-10286
    • Kumánovics, A.1    Chen, O.S.2    Li, L.3    Bagley, D.4    Adkins, E.M.5    Lin, H.6    Dingra, N.N.7    Outten, C.E.8    Keller, G.9    Winge, D.10    Ward, D.M.11    Kaplan, J.12
  • 24
    • 84876582502 scopus 로고    scopus 로고
    • Loss of vacuolar H+-ATPase (V-ATPase) activity in yeast generates an iron deprivation signal that is moderated by induction of the peroxiredoxin TSA2
    • Diab, H. I., and Kane, P. M. (2013) Loss of vacuolar H+-ATPase (V-ATPase) activity in yeast generates an iron deprivation signal that is moderated by induction of the peroxiredoxin TSA2. J. Biol. Chem. 288, 11366-11377
    • (2013) J. Biol. Chem. , vol.288 , pp. 11366-11377
    • Diab, H.I.1    Kane, P.M.2
  • 25
    • 84871011474 scopus 로고    scopus 로고
    • An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast
    • Hughes, A. L., and Gottschling, D. E. (2012) An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature 492, 261-265
    • (2012) Nature , vol.492 , pp. 261-265
    • Hughes, A.L.1    Gottschling, D.E.2
  • 26
    • 57749112116 scopus 로고    scopus 로고
    • A single amino acid change in the yeast vacuolar metal transporters ZRC1 and COT1 alters their substrate specificity
    • Lin, H., Kumánovics, A., Nelson, J. M., Warner, D. E., Ward, D. M., and Kaplan, J. (2008) A single amino acid change in the yeast vacuolar metal transporters ZRC1 and COT1 alters their substrate specificity. J. Biol. Chem. 283, 33865-33873
    • (2008) J. Biol. Chem. , vol.283 , pp. 33865-33873
    • Lin, H.1    Kumánovics, A.2    Nelson, J.M.3    Warner, D.E.4    Ward, D.M.5    Kaplan, J.6
  • 27
    • 34248649906 scopus 로고    scopus 로고
    • Phylogenetic and functional analysis of the cation diffusion facilitator (CDF) family: Improved signature and prediction of substrate specificity
    • Montanini, B., Blaudez, D., Jeandroz, S., Sanders, D., and Chalot, M. (2007) Phylogenetic and functional analysis of the cation diffusion facilitator (CDF) family: improved signature and prediction of substrate specificity. BMC Genomics 8, 107
    • (2007) BMC Genomics , vol.8 , pp. 107
    • Montanini, B.1    Blaudez, D.2    Jeandroz, S.3    Sanders, D.4    Chalot, M.5
  • 28
    • 79957660884 scopus 로고    scopus 로고
    • A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function
    • Seo, Y. A., Lopez, V., and Kelleher, S. L. (2011) A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function. Am. J. Physiol. Cell Physiol. 300, C1479-1489
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300
    • Seo, Y.A.1    Lopez, V.2    Kelleher, S.L.3
  • 29
    • 84895065690 scopus 로고    scopus 로고
    • Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells
    • Bostanci, Z., Alam, S., Soybel, D. I., and Kelleher, S. L. (2014) Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells. Exp. Cell Res. 321, 190-200
    • (2014) Exp. Cell Res. , vol.321 , pp. 190-200
    • Bostanci, Z.1    Alam, S.2    Soybel, D.I.3    Kelleher, S.L.4
  • 30
    • 79953117091 scopus 로고    scopus 로고
    • Structure and evolution of the plant cation diffusion facilitator family of ion transporters
    • Gustin, J. L., Zanis, M. J., and Salt, D. E. (2011) Structure and evolution of the plant cation diffusion facilitator family of ion transporters. BMC Evol. Biol. 11, 76
    • (2011) BMC Evol. Biol. , vol.11 , pp. 76
    • Gustin, J.L.1    Zanis, M.J.2    Salt, D.E.3


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