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Volumn 4, Issue 5, 2014, Pages 546-555

Longitudinal PET imaging of muscular inflammation using 18F-DPA-714 and 18F-alfatide II and differentiation with tumors

Author keywords

Inflammation; Positron emission tomography; TSPO; Tumor

Indexed keywords

18F ALFATIDE II; 18F DPA 714; ARGININE; ASPARAGINE; CLODRONIC ACID; GLYCINE; TRACER; UNCLASSIFIED DRUG;

EID: 84902504921     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.8159     Document Type: Article
Times cited : (50)

References (40)
  • 1
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • doi:10.1038/nature05485
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006; 444: 860-7. doi:10.1038/nature05485.
    • (2006) Nature. , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 2
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease--a double-edged sword
    • Wyss-Coray T, Mucke L. Inflammation in neurodegenerative disease--a double-edged sword. Neuron. 2002; 35: 419-32.
    • (2002) Neuron. , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 3
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr. 2006; 83: 456S-60S.
    • (2006) Am J Clin Nutr. , vol.83
    • Libby, P.1
  • 4
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • doi:10.1038/nature01322
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002; 420: 860-7. doi:10.1038/nature01322.
    • (2002) Nature. , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 5
    • 0037870111 scopus 로고    scopus 로고
    • Clinical role of FDG PET in evaluation of cancer patients. Radiographics : a review publication of the Radiological Society of North America, Inc.
    • quiz 533, doi:10.1148/rg.232025705
    • Kostakoglu L, Agress H, Jr., Goldsmith SJ. Clinical role of FDG PET in evaluation of cancer patients. Radiographics : a review publication of the Radiological Society of North America, Inc. 2003; 23: 315-40; quiz 533. doi:10.1148/rg.232025705.
    • (2003) , vol.23 , pp. 315-340
    • Kostakoglu, L.1    Agress Jr., H.2    Goldsmith, S.J.3
  • 6
    • 84859735376 scopus 로고    scopus 로고
    • Role of fluorine 18 fluorodeoxyglucose positron emission tomography-computed tomography in focal and generalized infectious and inflammatory disorders
    • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, doi:10.1093/cid/cis193
    • Haroon A, Zumla A, Bomanji J. Role of fluorine 18 fluorodeoxyglucose positron emission tomography-computed tomography in focal and generalized infectious and inflammatory disorders. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2012; 54: 1333-41. doi:10.1093/cid/cis193.
    • (2012) , vol.54 , pp. 1333-1341
    • Haroon, A.1    Zumla, A.2    Bomanji, J.3
  • 7
    • 2542437040 scopus 로고    scopus 로고
    • Selectivity of 18F-FLT and 18F-FDG for differentiating tumor from inflammation in a rodent model
    • van Waarde A, Cobben DC, Suurmeijer AJ, Maas B, Vaalburg W, de Vries EF, et al. Selectivity of 18F-FLT and 18F-FDG for differentiating tumor from inflammation in a rodent model. J Nucl Med. 2004; 45: 695-700.
    • (2004) J Nucl Med. , vol.45 , pp. 695-700
    • van Waarde, A.1    Cobben, D.C.2    Suurmeijer, A.J.3    Maas, B.4    Vaalburg, W.5    de Vries, E.F.6
  • 8
    • 55849129948 scopus 로고    scopus 로고
    • Noninvasive imaging of macrophages in rheumatoid synovitis using 11C-(R)-PK11195 and positron emission tomography
    • doi:10.1002/art.23955
    • van der Laken CJ, Elzinga EH, Kropholler MA, Molthoff CF, van der Heijden JW, Maruyama K, et al. Noninvasive imaging of macrophages in rheumatoid synovitis using 11C-(R)-PK11195 and positron emission tomography. Arthritis Rheum. 2008; 58: 3350-5. doi:10.1002/art.23955.
    • (2008) Arthritis Rheum , vol.58 , pp. 3350-3355
    • van der Laken, C.J.1    Elzinga, E.H.2    Kropholler, M.A.3    Molthoff, C.F.4    van der Heijden, J.W.5    Maruyama, K.6
  • 9
    • 84855272503 scopus 로고    scopus 로고
    • Macrophage positron emission tomography imaging as a biomarker for preclinical rheumatoid arthritis: findings of a prospective pilot study
    • doi:10.1002/art.30655
    • Gent YY, Voskuyl AE, Kloet RW, van Schaardenburg D, Hoekstra OS, Dijkmans BA, et al. Macrophage positron emission tomography imaging as a biomarker for preclinical rheumatoid arthritis: findings of a prospective pilot study. Arthritis Rheum. 2012; 64: 62-6. doi:10.1002/art.30655.
    • (2012) Arthritis Rheum. , vol.64 , pp. 62-66
    • Gent, Y.Y.1    Voskuyl, A.E.2    Kloet, R.W.3    van Schaardenburg, D.4    Hoekstra, O.S.5    Dijkmans, B.A.6
  • 10
    • 84873901664 scopus 로고    scopus 로고
    • [18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats
    • doi:10.1371/journal.pone.0056441
    • Boutin H, Prenant C, Maroy R, Galea J, Greenhalgh AD, Smigova A, et al. [18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats. PLoS One. 2013; 8: e56441. doi:10.1371/journal.pone.0056441.
    • (2013) PLoS One. , vol.8
    • Boutin, H.1    Prenant, C.2    Maroy, R.3    Galea, J.4    Greenhalgh, A.D.5    Smigova, A.6
  • 11
    • 84881003411 scopus 로고    scopus 로고
    • Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke
    • doi:10.1371/journal.pone.0069529
    • Harhausen D, Sudmann V, Khojasteh U, Muller J, Zille M, Graham K, et al. Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. PLoS One. 2013; 8: e69529. doi:10.1371/journal.pone.0069529.
    • (2013) PLoS One. , vol.8
    • Harhausen, D.1    Sudmann, V.2    Khojasteh, U.3    Muller, J.4    Zille, M.5    Graham, K.6
  • 12
    • 77955888790 scopus 로고    scopus 로고
    • Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography
    • doi:10.1089/neu.2009.1196
    • Yu I, Inaji M, Maeda J, Okauchi T, Nariai T, Ohno K, et al. Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography. J Neurotrauma. 2010; 27: 1463-75. doi:10.1089/neu.2009.1196.
    • (2010) J Neurotrauma. , vol.27 , pp. 1463-1475
    • Yu, I.1    Inaji, M.2    Maeda, J.3    Okauchi, T.4    Nariai, T.5    Ohno, K.6
  • 13
    • 79953004994 scopus 로고    scopus 로고
    • In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders
    • doi:10.1523/JNEUROSCI.3076-10.2011
    • Maeda J, Zhang MR, Okauchi T, Ji B, Ono M, Hattori S, et al. In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders. J Neurosci. 2011; 31: 4720-30. doi:10.1523/JNEUROSCI.3076-10.2011.
    • (2011) J Neurosci. , vol.31 , pp. 4720-4730
    • Maeda, J.1    Zhang, M.R.2    Okauchi, T.3    Ji, B.4    Ono, M.5    Hattori, S.6
  • 14
    • 84864628850 scopus 로고    scopus 로고
    • Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography
    • doi:10.1093/eurheartj/ehr367
    • Gaemperli O, Shalhoub J, Owen DR, Lamare F, Johansson S, Fouladi N, et al. Imaging intraplaque inflammation in carotid atherosclerosis with 11C-PK11195 positron emission tomography/computed tomography. Eur Heart J. 2012; 33: 1902-10. doi:10.1093/eurheartj/ehr367.
    • (2012) Eur Heart J. , vol.33 , pp. 1902-1910
    • Gaemperli, O.1    Shalhoub, J.2    Owen, D.R.3    Lamare, F.4    Johansson, S.5    Fouladi, N.6
  • 15
    • 79851482138 scopus 로고    scopus 로고
    • Detection and quantification of large-vessel inflammation with 11C-(R)-PK11195 PET/CT
    • doi:10.2967/jnumed.110.079038
    • Lamare F, Hinz R, Gaemperli O, Pugliese F, Mason JC, Spinks T, et al. Detection and quantification of large-vessel inflammation with 11C-(R)-PK11195 PET/CT. J Nucl Med. 2011; 52: 33-9. doi:10.2967/jnumed.110.079038.
    • (2011) J Nucl Med. , vol.52 , pp. 33-39
    • Lamare, F.1    Hinz, R.2    Gaemperli, O.3    Pugliese, F.4    Mason, J.C.5    Spinks, T.6
  • 16
    • 58149303036 scopus 로고    scopus 로고
    • Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers
    • doi:10.1007/s00259-008-0908-9
    • Chauveau F, Boutin H, Van Camp N, Dolle F, Tavitian B. Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers. Eur J Nucl Med Mol Imaging. 2008; 35: 2304-19. doi:10.1007/s00259-008-0908-9.
    • (2008) Eur J Nucl Med Mol Imaging. , vol.35 , pp. 2304-2319
    • Chauveau, F.1    Boutin, H.2    Van Camp, N.3    Dolle, F.4    Tavitian, B.5
  • 17
    • 70350348248 scopus 로고    scopus 로고
    • [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis
    • doi:10.1007/s11307-009-0211-6
    • Doorduin J, Klein HC, Dierckx RA, James M, Kassiou M, de Vries EF. [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis. Mol Imaging Biol. 2009; 11: 386-98. doi:10.1007/s11307-009-0211-6.
    • (2009) Mol Imaging Biol. , vol.11 , pp. 386-398
    • Doorduin, J.1    Klein, H.C.2    Dierckx, R.A.3    James, M.4    Kassiou, M.5    de Vries, E.F.6
  • 18
    • 62449175342 scopus 로고    scopus 로고
    • Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation
    • doi:10.2967/jnumed.108.058669
    • Chauveau F, Van Camp N, Dolle F, Kuhnast B, Hinnen F, Damont A, et al. Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation. J Nucl Med. 2009; 50: 468-76. doi:10.2967/jnumed.108.058669.
    • (2009) J Nucl Med. , vol.50 , pp. 468-476
    • Chauveau, F.1    Van Camp, N.2    Dolle, F.3    Kuhnast, B.4    Hinnen, F.5    Damont, A.6
  • 21
    • 0036212743 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
    • Lue H, Kleemann R, Calandra T, Roger T, Bernhagen J. Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. Microbes Infect. 2002; 4: 449-60.
    • (2002) Microbes Infect. , vol.4 , pp. 449-460
    • Lue, H.1    Kleemann, R.2    Calandra, T.3    Roger, T.4    Bernhagen, J.5
  • 23
    • 84872027783 scopus 로고    scopus 로고
    • RGD peptide-conjugated multimodal NaGdF4:Yb3+/Er3+ nanophosphors for upconversion luminescence, MR, and PET imaging of tumor angiogenesis
    • doi:10.2967/jnumed.112.108043
    • Lee J, Lee TS, Ryu J, Hong S, Kang M, Im K, et al. RGD peptide-conjugated multimodal NaGdF4:Yb3+/Er3+ nanophosphors for upconversion luminescence, MR, and PET imaging of tumor angiogenesis. J Nucl Med. 2013; 54: 96-103. doi:10.2967/jnumed.112.108043.
    • (2013) J Nucl Med. , vol.54 , pp. 96-103
    • Lee, J.1    Lee, T.S.2    Ryu, J.3    Hong, S.4    Kang, M.5    Im, K.6
  • 24
    • 35348945922 scopus 로고    scopus 로고
    • PET imaging of acute and chronic inflammation in living mice
    • doi:10.1007/s00259-007-0451-0
    • Cao Q, Cai W, Li ZB, Chen K, He L, Li HC, et al. PET imaging of acute and chronic inflammation in living mice. Eur J Nucl Med Mol Imaging. 2007; 34: 1832-42. doi:10.1007/s00259-007-0451-0.
    • (2007) Eur J Nucl Med Mol Imaging. , vol.34 , pp. 1832-1842
    • Cao, Q.1    Cai, W.2    Li, Z.B.3    Chen, K.4    He, L.5    Li, H.C.6
  • 25
    • 70350435114 scopus 로고    scopus 로고
    • Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice
    • doi:10.1161/CIRCIMAGING.108.846865
    • Laitinen I, Saraste A, Weidl E, Poethko T, Weber AW, Nekolla SG, et al. Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice. Circ Cardiovasc Imaging. 2009; 2: 331-8. doi:10.1161/CIRCIMAGING.108.846865.
    • (2009) Circ Cardiovasc Imaging. , vol.2 , pp. 331-338
    • Laitinen, I.1    Saraste, A.2    Weidl, E.3    Poethko, T.4    Weber, A.W.5    Nekolla, S.G.6
  • 26
    • 84896405804 scopus 로고    scopus 로고
    • Comparison of Three Dimeric F-AlF-NOTA-RGD Tracers
    • doi:10.1007/s11307-013-0668-1
    • Guo J, Lang L, Hu S, Guo N, Zhu L, Sun Z, et al. Comparison of Three Dimeric F-AlF-NOTA-RGD Tracers. Mol Imaging Biol. 2013. doi:10.1007/s11307-013-0668-1.
    • (2013) Mol Imaging Biol.
    • Guo, J.1    Lang, L.2    Hu, S.3    Guo, N.4    Zhu, L.5    Sun, Z.6
  • 27
    • 33847133049 scopus 로고    scopus 로고
    • Comparison of dynamic FDG-microPET study in a rabbit turpentine-induced inflammatory model and in a rabbit VX2 tumor model
    • Hamazawa Y, Koyama K, Okamura T, Wada Y, Wakasa T, Okuma T, et al. Comparison of dynamic FDG-microPET study in a rabbit turpentine-induced inflammatory model and in a rabbit VX2 tumor model. Ann Nucl Med. 2007; 21: 47-55.
    • (2007) Ann Nucl Med. , vol.21 , pp. 47-55
    • Hamazawa, Y.1    Koyama, K.2    Okamura, T.3    Wada, Y.4    Wakasa, T.5    Okuma, T.6
  • 28
    • 0001929693 scopus 로고    scopus 로고
    • Cytokines in acute and chronic inflammation
    • Feghali CA, Wright TM. Cytokines in acute and chronic inflammation. Front Biosci. 1997; 2: d12-26.
    • (1997) Front Biosci. , vol.2
    • Feghali, C.A.1    Wright, T.M.2
  • 29
    • 79961209171 scopus 로고    scopus 로고
    • Macrophages play a key role in early blood brain barrier reformation after hypothermic brain injury
    • doi:10.1016/j.neulet.2011.06.062
    • Koneru R, Kobiler D, Lehrer S, Li J, van Rooijen N, Banerjee D, et al. Macrophages play a key role in early blood brain barrier reformation after hypothermic brain injury. Neurosci Lett. 2011; 501: 148-51. doi:10.1016/j.neulet.2011.06.062.
    • (2011) Neurosci Lett. , vol.501 , pp. 148-151
    • Koneru, R.1    Kobiler, D.2    Lehrer, S.3    Li, J.4    van Rooijen, N.5    Banerjee, D.6
  • 30
    • 78751682676 scopus 로고    scopus 로고
    • Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype
    • doi:10.1093/hmg/ddq523
    • Villalta SA, Rinaldi C, Deng B, Liu G, Fedor B, Tidball JG. Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype. Hum Mol Genet. 2011; 20: 790-805. doi:10.1093/hmg/ddq523.
    • (2011) Hum Mol Genet. , vol.20 , pp. 790-805
    • Villalta, S.A.1    Rinaldi, C.2    Deng, B.3    Liu, G.4    Fedor, B.5    Tidball, J.G.6
  • 31
    • 33845785972 scopus 로고    scopus 로고
    • Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo
    • doi:10.1113/jphysiol.2006.118265
    • Tidball JG, Wehling-Henricks M. Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo. J Physiol. 2007; 578: 327-36. doi:10.1113/jphysiol.2006.118265.
    • (2007) J Physiol. , vol.578 , pp. 327-336
    • Tidball, J.G.1    Wehling-Henricks, M.2
  • 32
    • 84866146612 scopus 로고    scopus 로고
    • Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model
    • doi:10.1002/art.33423
    • Li J, Hsu HC, Yang P, Wu Q, Li H, Edgington LE, et al. Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model. Arthritis Rheum. 2012; 64: 1098-109. doi:10.1002/art.33423.
    • (2012) Arthritis Rheum. , vol.64 , pp. 1098-1109
    • Li, J.1    Hsu, H.C.2    Yang, P.3    Wu, Q.4    Li, H.5    Edgington, L.E.6
  • 33
    • 0037307824 scopus 로고    scopus 로고
    • In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system
    • Denkinger CM, Denkinger M, Kort JJ, Metz C, Forsthuber TG. In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system. J Immunol. 2003; 170: 1274-82.
    • (2003) J Immunol. , vol.170 , pp. 1274-1282
    • Denkinger, C.M.1    Denkinger, M.2    Kort, J.J.3    Metz, C.4    Forsthuber, T.G.5
  • 34
    • 0036307628 scopus 로고    scopus 로고
    • Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice
    • Ohkawara T, Nishihira J, Takeda H, Hige S, Kato M, Sugiyama T, et al. Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology. 2002; 123: 256-70.
    • (2002) Gastroenterology. , vol.123 , pp. 256-270
    • Ohkawara, T.1    Nishihira, J.2    Takeda, H.3    Hige, S.4    Kato, M.5    Sugiyama, T.6
  • 35
    • 84883153306 scopus 로고    scopus 로고
    • PET imaging of inflammation biomarkers
    • doi:10.7150/thno.6592
    • Wu C, Li F, Niu G, Chen X. PET imaging of inflammation biomarkers. Theranostics. 2013; 3: 448-66. doi:10.7150/thno.6592.
    • (2013) Theranostics. , vol.3 , pp. 448-466
    • Wu, C.1    Li, F.2    Niu, G.3    Chen, X.4
  • 36
    • 58149215702 scopus 로고    scopus 로고
    • Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
    • doi:10.1038/mt.2008.220
    • Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J. Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Mol Ther. 2009; 17: 162-8. doi:10.1038/mt.2008.220.
    • (2009) Mol Ther. , vol.17 , pp. 162-168
    • Howard, K.A.1    Paludan, S.R.2    Behlke, M.A.3    Besenbacher, F.4    Deleuran, B.5    Kjems, J.6
  • 37
    • 0025019759 scopus 로고
    • Specific high-affinity binding of peripheral benzodiazepine receptor ligands to brain tumors in rat and man
    • Black KL, Ikezaki K, Santori E, Becker DP, Vinters HV. Specific high-affinity binding of peripheral benzodiazepine receptor ligands to brain tumors in rat and man. Cancer. 1990; 65: 93-7.
    • (1990) Cancer. , vol.65 , pp. 93-97
    • Black, K.L.1    Ikezaki, K.2    Santori, E.3    Becker, D.P.4    Vinters, H.V.5
  • 38
    • 79958262835 scopus 로고    scopus 로고
    • Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer
    • doi:10.1021/mp100433c
    • Zheng J, Boisgard R, Siquier-Pernet K, Decaudin D, Dolle F, Tavitian B. Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer. Mol Pharm. 2011; 8: 823-32. doi:10.1021/mp100433c.
    • (2011) Mol Pharm. , vol.8 , pp. 823-832
    • Zheng, J.1    Boisgard, R.2    Siquier-Pernet, K.3    Decaudin, D.4    Dolle, F.5    Tavitian, B.6
  • 39
    • 84862128998 scopus 로고    scopus 로고
    • Differentiation and gene expression profile of tumor-associated macrophages
    • doi:10.1016/j.semcancer.2012.02.002
    • Schmieder A, Michel J, Schonhaar K, Goerdt S, Schledzewski K. Differentiation and gene expression profile of tumor-associated macrophages. Seminars in cancer biology. 2012; 22: 289-97. doi:10.1016/j.semcancer.2012.02.002.
    • (2012) Seminars in cancer biology. , vol.22 , pp. 289-297
    • Schmieder, A.1    Michel, J.2    Schonhaar, K.3    Goerdt, S.4    Schledzewski, K.5
  • 40
    • 84868030361 scopus 로고    scopus 로고
    • Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
    • Quatromoni JG, Eruslanov E. Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. American journal of translational research. 2012; 4: 376-89.
    • (2012) American journal of translational research. , vol.4 , pp. 376-389
    • Quatromoni, J.G.1    Eruslanov, E.2


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