Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics

Theranostics

Volumn 4, Issue 5, 2014, Pages 487-497

  Shen, Jianliang ^a,b   Kim, Han Cheon ^b   Su, Hua ^a   Wang, Feng ^b,c   Wolfram, Joy ^b,d   Kirui, Dickson ^b   Mai, Junhua ^b   Mu, Chaofeng ^b   Ji, Liang Nian ^a   Mao, Zong Wan ^a   Shen, Haifa ^b,e  

^a SUN YAT SEN UNIVERSITY   (China)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c TONGJI UNIVERSITY   (China)

^d NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Cancer therapy; Delivery; Gene silencing; Mesoporous silica nanoparticle; siRNA

Indexed keywords

CYCLODEXTRIN; MESOPOROUS SILICA NANOPARTICLE; NANOPARTICLE; POLYETHYLENEIMINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BREAST CANCER; BREAST CANCER CELL LINE; CANCER CELL; CANCER INHIBITION; CANCER THERAPY; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MDA MB 231 CELL LINE; MOUSE; NONHUMAN; PKM2 GENE; STATIC ELECTRICITY; TUMOR XENOGRAFT;

CANCER THERAPY; DELIVERY; GENE SILENCING; MESOPOROUS SILICA NANOPARTICLE; SIRNA;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL PRODUCTS; CYCLODEXTRINS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; FEMALE; GENE KNOCKDOWN TECHNIQUES; MICE; NANOPARTICLES; NEOPLASMS; POLYETHYLENEIMINE; PYRUVATE KINASE; RNA, SMALL INTERFERING; SILICON DIOXIDE;

EID: 84902494149     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.8263     Document Type: Article

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