Electrophoretic deposition of gentamicin-loaded bioactive glass/chitosan composite coatings for orthopaedic implants

ACS Applied Materials and Interfaces

Volumn 6, Issue 11, 2014, Pages 8796-8806

  Pishbin, Fatemehsadat ^a   Mouriño, Viviana ^b,c   Flor, Sabrina ^b,c   Kreppel, Stefan ^a,d   Salih, Vehid ^e   Ryan, Mary P ^a   Boccaccini, Aldo R ^a,d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

bioactive glass; chitosan; coatings; drug delivery; electrophoretic deposition; gentamicin

Indexed keywords

ANTIBIOTICS; BIOACTIVE GLASS; CHITOSAN; COATINGS; DEPOSITION; DIFFUSION COATINGS; DRUG DELIVERY; ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ELECTROPHORETIC DEPOSITIONS; GENTAMICIN; IN-VITRO BIOACTIVITY; MULTIFUNCTIONAL COMPOSITES; ORTHOPAEDIC PROSTHESIS; PHOSPHATE-BUFFERED SALINES; SIMULATED BODY FLUIDS; STAINLESS STEEL SUBSTRATES;

COMPOSITE COATINGS;

ANTIINFECTIVE AGENT; BIOMATERIAL; CHITOSAN; GENTAMICIN; GLASS;

CELL CULTURE; DIFFERENTIAL SCANNING CALORIMETRY; HUMAN; ORTHOPEDICS; PROSTHESES AND ORTHOSES; SCANNING ELECTRON MICROSCOPY; THERMOGRAVIMETRY;

ANTI-BACTERIAL AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CELLS, CULTURED; CHITOSAN; COATED MATERIALS, BIOCOMPATIBLE; GENTAMICINS; GLASS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; ORTHOPEDICS; PROSTHESES AND IMPLANTS; THERMOGRAVIMETRY;

EID: 84902491241     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am5014166     Document Type: Article

References (58)

1. Duan, K.; Wang, R. Surface Modifications of Bone Implants through Wet Chemistry J. Mater. Chem. 2006, 16, 2309-2321
2. Wang, G.; Zreiqat, H. Functional Coatings or Films for Hard-Tissue Applications Materials 2010, 3, 3994-4050
3. Boccaccini, A. R.; Keim, S.; Ma, R.; Li, Y.; Zhitomorsky, I. Electrophoretic Deposition of Biomaterials J. R. Soc., Interface. 2010, 7, S581-S613
4. Khang, D.; Lu, J.; Yao, C.; Haberstroh, K. M.; Webster, T. J. The Role of Nanometer and Sub-Micron Surface Features on Vascular and Bone Cell Adhesion on Titanium Biomaterials 2008, 29, 970-983
5. Sola, A.; Bellucci, D.; Cannillo, V.; Cattini, A. Bioactive Glass Coatings: a Review Surf. Eng. 2011, 27, 560-572
6. Jones, J. R. Review of Bioactive Glass: From Hench to Hybrids Acta Biomater. 2013, 9, 4457-4486
7. Chen, Q. Z.; Blaker, J. J.; Boccaccini, A. R. Bioactive and Mechanically Strong Bioglass®-Poly(d, l -Lactic Acid) Composite Coatings on Surgical Sutures J. Biomed. Mater. Res., Part B 2006, 2, 354-363
8. Kim, J.-J.; Won, J.-E.; Shin, U. S.; Kim, H.-W. Improvement of Bioactive Glass Nanofiber by a Capillary-Driven Infiltration Coating with Degradable Polymers J. Am. Ceram. Soc. 2011, 94, 2812-2815
9. Rezwan, K.; Chen, Q. Z.; Blaker, J. J.; Boccaccini, A. R. Biodegradable and Bioactive Porous Polymer/Inorganic Composite Scaffolds for Bone Tissue Engineering Biomaterials 2006, 27, 3413-3431
10. Nijhuis, A.; Leeuwenburgh, S.; Jansen, J. Wet-Chemical Deposition of Functional Coatings for Bone Implantology Macromol. Biosci. 2010, 10, 1316-1329
11. Di Martino, A.; Sittinger, M.; Risbud, M. V. Chitosan: A Versatile Biopolymer for Orthopaedic Tissue-Engineering Biomaterials 2005, 26, 5983-5990
12. Muzzarelli, R. A. A. Chitosan Composites with Inorganics, Morphogenetic Proteins and Stem Cells, for Bone Regeneration Carbohydr. Polym. 2011, 83, 1433-1445
13. Davies, D. Understanding Biofilm Resistance to Antibacterial Agents Nat. Rev. Drug Discovery. 2003, 2, 114-122
14. Goodman, S. B.; Yao, Z.; Keeney, M.; Yang, F. The Future of Biologic Coatings for Orthopaedic Implants Biomaterials 2013, 34, 3174-3183
15. Porter, J. R.; Ruckh, T. T.; Popat, K. C. Bone Tissue Engineering: A Review in Bone Biomimetics and Drug Delivery Strategies Biotechnol. Prog. 2009, 25, 1539-1560
16. Simchi, A.; Tamjid, E.; Pishbin, F.; Boccaccini, A. R. Recent Progress in Inorganic and Composite Coatings with Bactericidal Capability for Orthopaedic Applications Nanomedicine 2011, 7, 22-39
17. Grahek, R.; Zupancic-Kralj, L. Identification of Gentamicin Impurities by Liquid Chromatography Tandem Mass Spectrometry J. Pharm. Biomed. Anal. 2009, 50, 1037-1043
18. Farrar, D.; Benson, R.; Milner, R. In Drug-Device Combination Products: Delivery Technologies and Applications; Lewis, A., Ed.; Woodhead Publishing Limited: Cambridge, UK, 2010; Chapter 8, pp 190-211.
19. Price, J.; Tencer, A.; Arm, D.; Bohach, G. Controlled Release of Antibiotics From Coated Orthopedic Implants J. Biomed. Mater. Res. 1996, 30, 281-286
20. Moskowitz, J. S.; Blaisse, M. R.; Samuel, R. E.; Hsu, H. P.; Harris, M. B.; Martin, S. D.; Lee, J. C.; Spector, M.; Hammond, P. T. The Effectiveness of the Controlled Release of Gentamicin from Polyelectrolyte Multilayers in the Treatment of Staphylococcus Aureus Infection in a Rabbit Bone Model Biomaterials 2010, 31, 6019-6030
21. Stigter, M.; Bezemer, J.; de Groot, K.; Layrolle, P. Incorporation of Different Antibiotics into Carbonated Hydroxyapatite Coatings on Titanium Implants, Release and Antibiotic Efficacy J. Controlled Release 2004, 99, 127-137
22. Aves, E. P.; Estevez, G. F.; Sader, M. S.; Sierra, J. C. G.; Yurell, J. C. L.; Bastos, I.; Soares, G. Hydroxyapatite Coating by Sol-Gel on Ti-6Al-4V Alloy as Drug Carrier J. Mater. Sci.: Mater. Med. 2009, 20, 543-547
23. Zhou, J.; Cai, X.; Cheng, K.; Weng, W.; Song, C.; Du, P.; Shen, G.; Han, G. Release Behaviors of Drug Loaded Chitosan/Calcium Phosphate Coatings on Titanium Thin Solid Films 2011, 519, 4658-4662
24. Sirc, J.; Kubinova, S.; Hobzova, R.; Stranska, D.; Kozlik, P.; Bosakova, Z.; Marekova, D.; Holan, V.; Sykova, E.; Michalek, J. Controlled Gentamicin Release from Multi-Layered Electrospun Nanofibrous Structures of Various Thicknesses Int. J. Nanomed. 2012, 7, 5315-5325
25. Besra, L.; Liu, M. A Review on Fundamentals and Applications of Electrophoretic Deposition (EPD) Prog. Mater. Sci. 2007, 52, 1-61
26. Zhitomirsky, D.; Roether, J. A.; Boccaccini, A. R.; Zhitomirsky, I. Electrophoretic Deposition of Bioactive Glass/Polymer Composite Coatings with and without HA Nanoparticle Inclusions for Biomedical Applications J. Mater. Process. Technol. 2009, 209, 1853-1860
27. Yang, C. C.; Lin, C. C.; Yen, S. K. Electrochemical Deposition of Vancomycin/Chitosan Composite on Ti Alloy J. Electrochem. Soc. 2011, 158, E152-E158
28. Patel, K. D.; El-Fiqi, A.; Lee, H. Y.; Singh, R. K.; Kim, D. A.; Lee, H. H.; Kim, H. W. Chitosan-Nanobioactive Glass Electrophoretic Coatings with Bone Regenerative and Drug Delivering Potential J. Mater. Chem. 2012, 22, 24945-24956
29. Patel, K. D.; Singh, R. K.; Lee, E.-J.; Han, C.-M.; Won, J.-E.; Knowles, J. C.; Kim, H.-W. Tailoring Solubility and Drug Release from Electrophoretic Deposited Chitosan-Gelatin Films on Titanium Surf. Coat. Technol. 2014, 242, 232-236
30. Wang, Y.; Zhang, W.; Zhang, J.; Sun, W.; Zhang, R.; Gu, H. Fabrication of a Novel Polymer-Free Nanostructured Drug-Eluting Coating for Cardiovascular Stents ACS Appl. Mater. Interfaces 2013, 5, 10337-10345
31. Liu, Y.; Wang, W.; Acharya, G.; Shim, Y.-B.; Choe, E.; Lee, C. Advanced Stent Coating for Drug Delivery and In Vivo Biocompatibility J. Nanopart. Res. 2013, 15, 1-16
32. Simchi, A.; Pishbin, F.; Boccaccini, A. R. Electrophoretic Deposition of Chitosan Mater. Lett. 2009, 63, 2253-2256
33. Pishbin, F.; Simchi, A.; Ryan, M. P.; Boccaccini, A. R. A Study of the Electrophoretic Deposition of Bioglass® Suspensions Using the Taguchi Experimental Design Approach J. Eur. Ceram. Soc. 2010, 30, 2963-2970
34. Pishbin, F.; Simchi, A.; Ryan, M. P.; Boccaccini, A. R. Electrophoretic Deposition of Chitosan/45S5 Bioglass® Composite Coatings for Orthopaedic Applications Surf. Coat. Technol. 2011, 205, 5260-5268
35. Pishbin, F.; Mourino, V.; Gilchrist, J. B.; McComb, D. W.; Kreppel, S.; Salih, V.; Ryan, M. P.; Boccaccini, A. R. Single-Step electrochemical Deposition of Antimicrobial Orthopaedic Coatings Based on a Bioactive Glass/Chitosan/Nano- Silver Composite System Acta Biomater. 2013, 9, 7469-7479
36. Sigma-Aldrich, Gentamicin Solution G1272 Product Information: http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Product-Information-Sheet/ g1272pis.Par.0001.File.tmp/g1272pis.pdf; last accessed 2014/05/06.
37. Kokubo, T.; Takadama, H. How Useful Is SBF in Predicting In Vivo Bone Bioactivity? Biomaterials 2006, 27, 2907-2915
38. Hench, L. L. In Biomaterials, Artificial Organs and Tissue Engineering; Hench, L. L.; Jones, J. R., Eds.; Woodhead Publishing Limited: Cambridge, UK, 2005; Chapter 12, pp 119-127.
39. Sampath, S. S.; Robinson, D. H. Comparison of New and Existing Spectrophotometric Methods for the Analysis of Tobramycin and Other Aminoglycosides J. Pharm. Sci. 1990, 79, 428-431
40. Clinical and Laboratory Standards Institute, CLSI M02-A10: Performance Standardsfor Antimicrobial Disk Susceptibility Tests; Approved Standard -TenthEdition, Published 01/07/2010, Wayne, PA.
41. Paluszkiewicz, C.; Stodolak, E.; Hasik, M.; Blazewicz, M. FT-IR Study of Montmorillonite-Chitosan Nanocomposite Materials Spectrochim. Acta, Part A 2011, 79, 784-788
42. Kontonasaki, E.; Zorba, T.; Papadopoulou, L.; Pavlidou, E.; Chatzistavrou, X.; Paraskevopoulos, K.; Koidis, P. Hydroxy Carbonate Apatite Formation on Particulate Bioglass® In Vitro as a Function of Time Cryst. Res. Technol. 2002, 37, 1165-1171
43. Coates, J. In Encyclopedia of Analytical Chemistry: Applications, Theory and Instrumentation; Meyers, R. A., Ed.; Wiley: Hoboken, NJ, 2006; pp 10815-10837.
44. Wanjun, T.; Cunxin, W.; Donghua, C. Kinetic Studies on the Pyrolysis of Chitin and Chitosan Poly. Degrad. Stab. 2005, 87, 389-394
45. Mourino, V.; Newby, P.; Pishbin, F.; Cattalini, J. P.; Lucangioli, S.; Boccaccini, A. R. Physicochemical, Biological and Drug-Release Properties of Gallium Crosslinked Alginate/Nanoparticulate Bioactive Glass Composite Films Soft Matter 2011, 7, 6705-6712
46. Jones, J. R.; Sepulveda, P.; Hench, L. L. Dose-Dependent Behavior of Bioactive Glass Dissolution J. Biomed. Mater. Res. 2001, 58, 720-726
47. Li, P.; Zhang, F. The Electrochemistry of a Glass Surface and Its Application to Bioactive Glass in Solution J. Non-Cryst. Solids 1990, 119, 112-118
48. Pishbin, F. Development and Characterisation of Bioactive Coatings Based on Biopolymer and Bioactive Glass Obtained by Electrochemical Means. Ph.D. Thesis, Imperial College London, London, UK, 2013.
49. Baudoux, P.; Bles, N.; Lemaire, S.; Mingeot-Leclercq, M.; Tulkens, P.; Van Bambeke, F. Combined Effect of pH and Concentration on the Activities of Gentamicin and Oxacillin Against Staphylococcus Aureus in Pharmacodynamic Models of Extracellular and Intracellular Infections J. Antimicrob. Chemother. 2007, 59, 246-253
50. Schafer, T. W. Evaluation of Gentamicin for Use in Virology and Tissue Culture Appl. Environ. Microbiol. 1972, 23, 565-570
51. Xue, J. M.; Shi, M. PLGA/Mesoporous Silica Hybrid Structure for Controlled Drug Release J. Controlled Release 2004, 98, 209-217
52. Kim, H. M.; Kishimoto, K.; Miyaji, F.; Kokubo, T.; Yao, T.; Suetsugu, Y.; Tanaka, J.; Nakamura, T. Composition and Structure of Apatite Formed on Organic Polymer in Simulated Body Fluid with a High Content of Carbonate Ion J. Mater. Sci.: Mater. Med. 2000, 11, 421-426
53. - Bone 1999, 25, 107S-111S
54. Bohner, M.; Lemaitre, J. Can Bioactivity Be Tested In Vitro with SBF Solution? Biomaterials 2009, 30, 2175-2179
55. Benson, J. R.; Hare, P. E. O-Phthalaldehyde: Fluorogenic Detection of Primary Amines in the Picomole Range. Comparison with Fluorescamine and Ninhydrin Proc. Natl. Acad. Sci. U.S.A. 1975, 72, 619-622
56. Mario, G.; Gabriele, G. Mathematical Modelling and Controlled Drug Delivery: Matrix Systems Curr. Drug Delivery 2005, 2, 97-116
57. Ehlert, N.; Badar, M.; Christel, A.; Lohmeier, S. J.; Luessenhop, T.; Stieve, M.; Lenarz, T.; Mueller, P. P.; Behrens, P. Mesoporous Silica Coatings for Controlled Release of the Antibiotic Ciprofloxacin from Implants J. Mater. Chem. 2011, 21, 752-760
58. Campos, M. G. N.; Rawls, H. R.; Innocentini-Mei, L. H.; Satsangi, N. In Vitro Gentamicin Sustained and Controlled Release from Chitosan Cross-Linked Films J. Mater. Sci.: Mater. Med. 2009, 20, 537-542