Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP

BMC Medical Genetics

Volumn 9, Issue , 2008, Pages

  Nexø, Bjørn A ^a   Vogel, Ulla ^b,j,k   Olsen, Anja ^c   Nyegaard, Mette ^a   Bukowy, Zuzanna ^a,d   Rockenbauer, Eszter ^a,b,e   Zhang, Xiuqing ^a,f   Koca, Cemile ^a   Mains, Mette ^a   Hansen, Bettina ^a   Hedemand, Anne ^a   Kjeldgaard, Anette ^a   Laska, Magdalena J ^a,g   Raaschou Nielsen, Ole ^c   Cold, Søren ^h   Overvad, Kim ⁱ   Tjønneland, Anne ^c   Bolund, Lars ^a,f   Børglum, Anders D ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

^c INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^d INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f BGI SHENZHEN   (China)

^g UNIVERSITY OF SILESIA   (Poland)

^h ODENSE UNIVERSITY HOSPITAL   (Denmark)

ⁱ AALBORG UNIVERSITY HOSPITAL   (Denmark)

^j ROSKILDE UNIVERSITY   (Denmark)

^k TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GENE PRODUCT; PROTEIN RAI; XERODERMA PIGMENTOSUM GROUP D PROTEIN; PPP1R13L PROTEIN, HUMAN; SIGNAL PEPTIDE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADULT; ARTICLE; BREAST CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CHROMOSOME 19Q; CONTROLLED STUDY; DENMARK; DISEASE MARKER; FEMALE; FOLLOW UP; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; POSTMENOPAUSE; SEQUENCE ANALYSIS; TANDEM REPEAT; BREAST TUMOR; CHROMOSOME 19; CHROMOSOME MAP; COHORT ANALYSIS; DNA SEQUENCE; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

ALIAS;

BREAST NEOPLASMS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 19; COHORT STUDIES; DENMARK; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LINKAGE DISEQUILIBRIUM; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 47249131653     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-9-56     Document Type: Article

References (31)

1. Dybdahl M Vogel U Frentz G Wallin H Nexø BA Polymorphisms in the DNA repair gene XPD: Correlations with risk and age at onset of basal cell carcinoma Cancer Epidemiol Biomarkers Prev 1999, 8:77-81. 9950243
2. Vogel U Hedayati M Dybdahl M Grossman L Nexø BA Polymorphisms of the DNA repair gene XPD: Correlations with risk of basal cell carcinoma revisited Carcinogenesis 2001, 22:899-904. 10.1093/carcin/22.6.899 11375896
3. Tomescu D Kavanagh G Ha T Campbell H Melton DW Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma Carcinogenesis 2001, 22:403-408. 10.1093/carcin/22.3.403 11238179
4. Caggana M Kilgallen J Conroy JM Wiencke JK Kelsey KT Miike R Chen P Wrensch MR Associations between ERCC2 polymorphisms and glioma Cancer Epidemiol Biomarkers Prev 2001, 10:355-360. 11319176
5. Butkiewicz D Rusin M Enewold L Shields PG Chorazy M Harris CC Genetic polymorphisms in DNA repair genes and risk of lung cancer Carcinogenesis 2001, 22:593-597. 10.1093/carcin/22.4.593 11285194
6. Spitz MR Wu X Wang Y Wang LE Shete S Amos CI Guo Z Lei L Mohrenweiser H Wei Q Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients Cancer Res 2001, 61:1354-1357. 11245433
7. Rockenbauer E Bendixen MH Bukowy Z Yin J Jacobsen NR Hedayati M Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: Tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts Carcinogenesis 2002, 23:1149-1153. 10.1093/carcin/23.7.1149 12117772
8. Yin J Rockenbauer E Hedayati M Jacobsen NR Vogel U Grossman L Bolund L Nexø BA Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of basal cell carcinoma Cancer Epidemiol Biomarkers Prev 2002, 11:1449-1453. 12433725
9. Nexø BA Vogel U Olsen A Ketelsen T Bukowy Z Thomsen B Wallin H Overvad K Tjønneland A A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of postmenopausal breast cancer at an early age Carcinogenesis 2003, 24:899-904. 10.1093/carcin/bgg043 12771034
10. Vogel U Laros I Jacobsen NR Thomsen BL Bak H Olsen A Bukowy Z Wallin H Obervad K Tjønneland A Nexø BA Raaschou-Nielsen O Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer Mutat Res 2004, 546:65-74. 14757194
11. Vogel U Sørensen M Hansen RD Tjønneland A Overvad K Wallin H Nexø BA Raaschou-Nielsen O Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer Cancer Letters 2007, 247:159-165. 10.1016/j.canlet.2006.04.001 16690207
12. Skjelbred CF Sæbø M Nexø BA Wallin H Hansteen I-L Vogel U Kure EH Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: A case control study BMC Cancer 2006, 6:175. 1533843 16817948 10.1186/1471-2407-6-175
13. Laska MJ Nexø BA Vistisen K Poulsen HE Loft S Vogel U Polymorphisms in RAI and in DNA repair Genes Are not associated with Risk of Testicular Cancer Cancer Letters 2005, 225:245-251. 10.1016/ j.canlet.2005.03.021 15885892
14. Hansen RD Sørensen M Tjønneland A Overvad K Wallin H Raaschou-Nielsen O Vogel U Polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer BMC Cancer 2008, 8(1):54. 2263058 18289367 10.1186/1471-2407-8-54
15. Zaykin DV Westfall PH Young SS Karnoub MA Wagner MJ Ehm MG Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals Hum Hered 2002, 53:79-91. 10.1159/000057986 12037407
16. Hemminki K Forsti A Proper controls for SNP studies Carcinogenesis 2001, 23:1405. 10.1093/carcin/23.8.1405 12151361
17. SISA: Simple interactive statistical analysis http://home.clara.net/sisa/
18. Vogel U Nexø BA Tjønneland A Wallin H Hertel O Raaschou-Nielsen O ERCC1, XPD and RAI mRNA levels in lymphocytes are not associated with lung cancer risk in a prospective study of Danes Mutat Res 2006, 593:88-96. 16054657
19. Vogel U Dybdahl M Frentz G Nexø BA DNA repair capacity: Inconsistency between effect of overexpression of five NER genes and the correlation to mRNA levels in primary lymphocytes Mutation Research 2000, 461:197-210. 10.1016/S0921-8777(00)00051-3 11056291
20. Yang JP Hori M Sanda Y Okamoto T Identification of a novel inhibitor if nuclear factor.kappaB, RelA-associated inhibitor J Biol Chem 1999, 274:15662-15670. 10.1074/jbc.274.22.15662 10336463
21. Takada N Sanda T Okamoto H Yang JP Asamitsu K Sarol L RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and SP1 actions J Virol 2002, 76:8019-8030. 155123 12134007 10.1128/JVI.76.16.8019-8030.2002
22. Chen X Kandasamy K Srivastava RK Differential role of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signalling Cancer Res 2003, 63:1059-1066. 12615723
23. Laska MJ Strandbygård D Kjeldgaard A Mains M Corydon TJ Memon A Vogel U Jensen UB Nexø BA Expression of the RAI gene is conducive to apoptosis: Studies of induction and interference Experimental Cell Res 2007, 313:2611-21. 17570360 10.1016/j.yexcr.2007.05.006
24. Bergamaschi D Samuels Y O'Niel NJ Trigiante G Crook T Hsieh JK O'Conner DJ Zhong S Camparque I Tomlinson ML Kuwabara PE Lu X iASPP oncoprotein is a key inhibitor of p53 conserved from worm to man Nat Genet 2003, 33:162-167. 10.1038/ng1070 12524540
25. Sæbø M Skjelbred CF Hansteen I-L Nexø BA Wallin H Vogel U Kure EH Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas BMC Cancer 2006, 6:208. 1562435 16914027 10.1186/1471-2407-6-208
26. Wu X GU J Grossman HB Amos CI Etzel C Huang M Zhang Q Lerner S Dinney CP Spitz MR Bladder cancer predispositions: A multigenic approach to DNA-repair and cell-cycle-control genes Am J Hum Genet 2006, 78:464-79. 1380289 16465622 10.1086/500848
27. Sturgis EM Zheng R Li L Castillo EJ Eicher SA Chen M Strom SS Spitz MR Wei Q XPD/ERCC2 polymorphisms and risk of head and neck cancer: A case-control analysis Carcinogenesis 2000, 21:2219-2223. 10.1093/carcin/ 21.12.2219 11133811
28. Tjønneland AM Olsen A Boll K Stripp C Christensen J Engholm G Overvad K Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: A population-based prospective cohort study of 57,053 men and women in Denmark Scand J Public Health 2007, 35:432-441. 10.1080/ 14034940601047986 17786808
29. Storm HH Michelsen EV Clemmensen IH Pihl J The Danish Cancer Registry - history, content, quality and use Dan Med Bull 1997, 44:535-539. 9408738
30. Schneider S Roessli D Excoffier L Arlequin ver. 2.000: A software for population genetics data analysis Genetics and Biometry Laboratory, University of Geneva, Switzerland 2000
31. Stephens M Smith NJ Donnelly P A new statistical method for haplotype reconstruction from population data Am J Hum Genet 2001, 68:978-989. 1275651 11254454 10.1086/319501