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Volumn 33, Issue 24, 2014, Pages 3119-3128

MicroRNA-30a suppresses breast tumor growth and metastasis by targeting metadherin

Author keywords

breast cancer; metadherin; metastasis; miR 30a

Indexed keywords

MICRORNA; MICRORNA 30A; RNA; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84902463420     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.286     Document Type: Article
Times cited : (146)

References (53)
  • 2
    • 80054686286 scopus 로고    scopus 로고
    • Tumor metastasis: Molecular insights and evolving paradigms
    • Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275-292.
    • (2011) Cell , vol.147 , pp. 275-292
    • Valastyan, S.1    Weinberg, R.A.2
  • 3
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003; 3: 453-458.
    • (2003) Nat Rev Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 5
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011; 331: 1559-1564.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 7
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • Ambros V. MicroRNAs: tiny regulators with great potential. Cell 2001; 107: 823-826.
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 8
    • 53549097349 scopus 로고    scopus 로고
    • MicroRNAs: Key players in the immune system, differentiation, tumorigenesis and cell death
    • Schickel R, Boyerinas B, Park SM, Peter ME. MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene 2008; 27: 5959-5974.
    • (2008) Oncogene , vol.27 , pp. 5959-5974
    • Schickel, R.1    Boyerinas, B.2    Park, S.M.3    Peter, M.E.4
  • 9
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 11
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004; 101: 2999-3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yendamuri, S.6
  • 12
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 13
    • 84861345640 scopus 로고    scopus 로고
    • MicroRNA-mediated breast cancer metastasis: From primary site to distant organs
    • Wang L, Wang J. MicroRNA-mediated breast cancer metastasis: from primary site to distant organs. Oncogene 2012; 31: 2499-2511.
    • (2012) Oncogene , vol.31 , pp. 2499-2511
    • Wang, L.1    Wang, J.2
  • 14
    • 70450203075 scopus 로고    scopus 로고
    • The miR-30 miRNA family regulates xenopus pronephros development and targets the transcription factor Xlim1/Lhx1
    • Agrawal R, Tran U, Wessely O. The miR-30 miRNA family regulates xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development 2009; 136: 3927-3936.
    • (2009) Development , vol.136 , pp. 3927-3936
    • Agrawal, R.1    Tran, U.2    Wessely, O.3
  • 16
    • 77951879469 scopus 로고    scopus 로고
    • Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas
    • Xia Z, Zhang N, Jin H, Yu Z, Xu G, Huang Z. Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. Clin Neurol Neurosurg 2010; 112: 413-419.
    • (2010) Clin Neurol Neurosurg , vol.112 , pp. 413-419
    • Xia, Z.1    Zhang, N.2    Jin, H.3    Yu, Z.4    Xu, G.5    Huang, Z.6
  • 17
    • 69449097865 scopus 로고    scopus 로고
    • Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
    • Zhu H, Wu H, Liu X, Li B, Chen Y, Ren X et al. Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy 2009; 5: 816-823.
    • (2009) Autophagy , vol.5 , pp. 816-823
    • Zhu, H.1    Wu, H.2    Liu, X.3    Li, B.4    Chen, Y.5    Ren, X.6
  • 18
    • 84863011747 scopus 로고    scopus 로고
    • MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy
    • Zou Z, Wu L, Ding H, Wang Y, Zhang Y, Chen X et al. MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. J Biol Chem 2012; 287: 4148-4156.
    • (2012) J Biol Chem , vol.287 , pp. 4148-4156
    • Zou, Z.1    Wu, L.2    Ding, H.3    Wang, Y.4    Zhang, Y.5    Chen, X.6
  • 19
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 23
    • 57849134562 scopus 로고    scopus 로고
    • MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer
    • Hu G, Chong RA, Yang Q, Wei Y, Blanco MA, Li F et al. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 2009; 15: 9-20.
    • (2009) Cancer Cell , vol.15 , pp. 9-20
    • Hu, G.1    Chong, R.A.2    Yang, Q.3    Wei, Y.4    Blanco, M.A.5    Li, F.6
  • 24
    • 82755189644 scopus 로고    scopus 로고
    • MicroRNA history: Discovery, recent applications, and next frontiers
    • Almeida MI, Reis RM, Calin GA. MicroRNA history: discovery, recent applications, and next frontiers. Mutat Res 2011; 717: 1-8.
    • (2011) Mutat Res , vol.717 , pp. 1-8
    • Almeida, M.I.1    Reis, R.M.2    Calin, G.A.3
  • 25
    • 33747628074 scopus 로고    scopus 로고
    • Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
    • Bandres E, Cubedo E, Agirre X, Malumbres R, Zarate R, Ramirez N et al. Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 2006; 5: 29.
    • (2006) Mol Cancer , vol.5 , pp. 29
    • Bandres, E.1    Cubedo, E.2    Agirre, X.3    Malumbres, R.4    Zarate, R.5    Ramirez, N.6
  • 27
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006; 9: 189-198.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4    Kumamoto, K.5    Yi, M.6
  • 28
    • 40949087185 scopus 로고    scopus 로고
    • Identification of metastasis-related microRNAs in hepatocellular carcinoma
    • Budhu A, Jia HL, Forgues M, Liu CG, Goldstein D, Lam A et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008; 47: 897-907.
    • (2008) Hepatology , vol.47 , pp. 897-907
    • Budhu, A.1    Jia, H.L.2    Forgues, M.3    Liu, C.G.4    Goldstein, D.5    Lam, A.6
  • 29
    • 84868206492 scopus 로고    scopus 로고
    • MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer
    • Cheng CW, Wang HW, Chang CW, Chu HW, Chen CY, Yu JC et al. MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat 2012; 134: 1081-1093.
    • (2012) Breast Cancer Res Treat , vol.134 , pp. 1081-1093
    • Cheng, C.W.1    Wang, H.W.2    Chang, C.W.3    Chu, H.W.4    Chen, C.Y.5    Yu, J.C.6
  • 30
    • 84883742665 scopus 로고    scopus 로고
    • MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
    • (e-pub ahead of print 24 September 2012; doi: 10.1038/onc.2012.432)
    • Yang S, Li Y, Gao J, Zhang T, Li S, Luo A et al. MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1. Oncogene (e-pub ahead of print 24 September 2012; doi: 10.1038/onc.2012.432).
    • Oncogene
    • Yang, S.1    Li, Y.2    Gao, J.3    Zhang, T.4    Li, S.5    Luo, A.6
  • 31
    • 8244259928 scopus 로고    scopus 로고
    • Loss of heterozygosity at chromosome 6q in preinvasive and early invasive breast carcinomas
    • Chappell SA, Walsh T, Walker RA, Shaw JA. Loss of heterozygosity at chromosome 6q in preinvasive and early invasive breast carcinomas. Br J Cancer 1997; 75: 1324-1329.
    • (1997) Br J Cancer , vol.75 , pp. 1324-1329
    • Chappell, S.A.1    Walsh, T.2    Walker, R.A.3    Shaw, J.A.4
  • 32
    • 0030223060 scopus 로고    scopus 로고
    • Loss of heterozygosity on the long arm of chromosom 6 in breast cancer: Possibly four regions of deletion
    • Noviello C, Courjal F, Theillet C. Loss of heterozygosity on the long arm of chromosom. 6 in breast cancer: possibly four regions of deletion. Clin Cancer Res 1996; 2: 1601-1606.
    • (1996) Clin Cancer Res , vol.2 , pp. 1601-1606
    • Noviello, C.1    Courjal, F.2    Theillet, C.3
  • 35
    • 77954954098 scopus 로고    scopus 로고
    • Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
    • Yu F, Deng H, Yao H, Liu Q, Su F, Song E. Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells. Oncogene 2010; 29: 4194-4204.
    • (2010) Oncogene , vol.29 , pp. 4194-4204
    • Yu, F.1    Deng, H.2    Yao, H.3    Liu, Q.4    Su, F.5    Song, E.6
  • 36
    • 79954748720 scopus 로고    scopus 로고
    • MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer
    • Rodriguez-Gonzalez FG, Sieuwerts AM, Smid M, Look MP, Meijer-van Gelder ME, de Weerd V et al. MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer. Breast Cancer Res Treat 2011; 127: 43-51.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 43-51
    • Rodriguez-Gonzalez, F.G.1    Sieuwerts, A.M.2    Smid, M.3    Look, M.P.4    Meijer-Van Gelder, M.E.5    De Weerd, V.6
  • 37
    • 50349090038 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival
    • Li J, Zhang N, Song LB, Liao WT, Jiang LL, Gong LY et al. Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival. Clin Cancer Res 2008; 14: 3319-3326.
    • (2008) Clin Cancer Res , vol.14 , pp. 3319-3326
    • Li, J.1    Zhang, N.2    Song, L.B.3    Liao, W.T.4    Jiang, L.L.5    Gong, L.Y.6
  • 38
    • 79251475257 scopus 로고    scopus 로고
    • Significance of aeg-1 expression in correlation with vegf, microvessel density and clinicopathological characteristics in triple-negative breast cancer
    • Li C, Li R, Song H, Wang D, Feng T, Yu X et al. Significance of aeg-1 expression in correlation with vegf, microvessel density and clinicopathological characteristics in triple-negative breast cancer. J Surg Oncol 2010; 103: 184-192.
    • (2010) J Surg Oncol , vol.103 , pp. 184-192
    • Li, C.1    Li, R.2    Song, H.3    Wang, D.4    Feng, T.5    Yu, X.6
  • 39
    • 36849061266 scopus 로고    scopus 로고
    • Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity
    • Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y et al. Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene 2007; 26: 7647-7655.
    • (2007) Oncogene , vol.26 , pp. 7647-7655
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3    Kawamoto, K.4    Hirata, H.5    Tanaka, Y.6
  • 40
    • 67650076377 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma
    • Lee SG, Jeon HY, Su ZZ, Richards JE, Vozhilla N, Sarkar D et al. Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma. Oncogene 2009; 28: 2476-2484.
    • (2009) Oncogene , vol.28 , pp. 2476-2484
    • Lee, S.G.1    Jeon, H.Y.2    Su, Z.Z.3    Richards, J.E.4    Vozhilla, N.5    Sarkar, D.6
  • 41
    • 65649143486 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression
    • Yoo BK, Emdad L, Su ZZ, Villanueva A, Chiang DY, Mukhopadhyay ND et al. Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. J Clin Invest 2009; 119: 465-477.
    • (2009) J Clin Invest , vol.119 , pp. 465-477
    • Yoo, B.K.1    Emdad, L.2    Su, Z.Z.3    Villanueva, A.4    Chiang, D.Y.5    Mukhopadhyay, N.D.6
  • 42
    • 70349459893 scopus 로고    scopus 로고
    • The multifaceted role of MTDH/AEG-1 in cancer progression
    • Hu G, Wei Y, Kang Y. The multifaceted role of MTDH/AEG-1 in cancer progression. Clin Cancer Res 2009; 15: 5615-5620.
    • (2009) Clin Cancer Res , vol.15 , pp. 5615-5620
    • Hu, G.1    Wei, Y.2    Kang, Y.3
  • 43
    • 84874735111 scopus 로고    scopus 로고
    • Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
    • Ward A, Balwierz A, Zhang JD, Kublbeck M, Pawitan Y, Hielscher T et al. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene 2012; 32: 1173-1182.
    • (2012) Oncogene , vol.32 , pp. 1173-1182
    • Ward, A.1    Balwierz, A.2    Zhang, J.D.3    Kublbeck, M.4    Pawitan, Y.5    Hielscher, T.6
  • 44
    • 84875980153 scopus 로고    scopus 로고
    • The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) in breast cancer
    • Zhang N, Wang X, Huo Q, Li X, Wang H, Schneider P et al. The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) in breast cancer. J Biol Chem 2013; 288: 9396-9407.
    • (2013) J Biol Chem , vol.288 , pp. 9396-9407
    • Zhang, N.1    Wang, X.2    Huo, Q.3    Li, X.4    Wang, H.5    Schneider, P.6
  • 45
    • 84863034803 scopus 로고    scopus 로고
    • Inhibition of metadherin sensitizes breast cancer cells to AZD6244
    • Kong X, Moran MS, Zhao Y, Yang Q. Inhibition of metadherin sensitizes breast cancer cells to AZD6244. Cancer Biol Ther 2012; 13: 43-49.
    • (2012) Cancer Biol Ther , vol.13 , pp. 43-49
    • Kong, X.1    Moran, M.S.2    Zhao, Y.3    Yang, Q.4
  • 46
    • 80052120906 scopus 로고    scopus 로고
    • Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC)
    • Nohata N, Hanazawa T, Kikkawa N, Mutallip M, Sakurai D, Fujimura L et al. Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC). J Hum Genet 2011; 56: 595-601.
    • (2011) J Hum Genet , vol.56 , pp. 595-601
    • Nohata, N.1    Hanazawa, T.2    Kikkawa, N.3    Mutallip, M.4    Sakurai, D.5    Fujimura, L.6
  • 48
    • 84874735111 scopus 로고    scopus 로고
    • Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
    • Ward A, Balwierz A, Zhang JD, Kublbeck M, Pawitan Y, Hielscher T et al. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene 2013; 32: 1173-1182.
    • (2013) Oncogene , vol.32 , pp. 1173-1182
    • Ward, A.1    Balwierz, A.2    Zhang, J.D.3    Kublbeck, M.4    Pawitan, Y.5    Hielscher, T.6
  • 49
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008; 9: 102-114.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 50
    • 84857507248 scopus 로고    scopus 로고
    • MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer
    • Kumarswamy R, Mudduluru G, Ceppi P, Muppala S, Kozlowski M, Niklinski J et al. MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer. Int J Cancer 2012; 130: 2044-2053.
    • (2012) Int J Cancer , vol.130 , pp. 2044-2053
    • Kumarswamy, R.1    Mudduluru, G.2    Ceppi, P.3    Muppala, S.4    Kozlowski, M.5    Niklinski, J.6
  • 51
    • 1842634484 scopus 로고    scopus 로고
    • Metadherin, a cell surface protein in breast tumors that mediates lung metastasis
    • Brown DM, Ruoslahti E. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 2004; 5: 365-374.
    • (2004) Cancer Cell , vol.5 , pp. 365-374
    • Brown, D.M.1    Ruoslahti, E.2
  • 52
    • 77958599007 scopus 로고    scopus 로고
    • Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis
    • Zhang N, Kong X, Yan S, Yuan C, Yang Q. Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis. Cancer Sci 2010; 101: 2375-2383.
    • (2010) Cancer Sci , vol.101 , pp. 2375-2383
    • Zhang, N.1    Kong, X.2    Yan, S.3    Yuan, C.4    Yang, Q.5
  • 53
    • 34248559599 scopus 로고    scopus 로고
    • Gene splicing and mutagenesis by PCR-driven overlap extension
    • Heckman KL, Pease LR. Gene splicing and mutagenesis by PCR-driven overlap extension. Nat Protocols 2007; 2: 924-932.
    • (2007) Nat Protocols , vol.2 , pp. 924-932
    • Heckman, K.L.1    Pease, L.R.2


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