메뉴 건너뛰기




Volumn 6, Issue 11, 2014, Pages 8090-8097

Advanced micromachining of concave microwells for long term on-chip culture of multicellular tumor spheroids

Author keywords

drug screening; micromilling; microwells; multicellular tumor spheroids; pluronics; polydimethylsiloxane

Indexed keywords

ASSAYS; COMPOSITE MICROMECHANICS; MOLDS; POLYDIMETHYLSILOXANE; SILICONES;

EID: 84902438572     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am500367h     Document Type: Article
Times cited : (49)

References (36)
  • 3
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-Based Drug Screen: Considerations and Practical Approach
    • Friedrich, J.; Seidel, C.; Ebner, R.; Kunz-Schughart, L. Spheroid-Based Drug Screen: Considerations and Practical Approach Nat. Protoc. 2009, 4, 309-324
    • (2009) Nat. Protoc. , vol.4 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3    Kunz-Schughart, L.4
  • 4
    • 0033800091 scopus 로고    scopus 로고
    • Multicellular Resistance: A Paradigm for Clinical Resistance?
    • Desoize, B.; Jardillier, J. C. Multicellular Resistance: a Paradigm for Clinical Resistance? Crit. Rev. Oncol. Hematol. 2000, 36, 193-207
    • (2000) Crit. Rev. Oncol. Hematol. , vol.36 , pp. 193-207
    • Desoize, B.1    Jardillier, J.C.2
  • 5
    • 84869495994 scopus 로고    scopus 로고
    • Opportunities and Challenges for Use of Tumor Spheroids as Models to Test Drug Delivery and Efficacy
    • Mehta, G.; Hsiao, A. Y.; Ingram, M.; Luker, G. D.; Takayama, S. Opportunities and Challenges for Use of Tumor Spheroids as Models to Test Drug Delivery and Efficacy J. Control. Release 2012, 164, 192-204
    • (2012) J. Control. Release , vol.164 , pp. 192-204
    • Mehta, G.1    Hsiao, A.Y.2    Ingram, M.3    Luker, G.D.4    Takayama, S.5
  • 6
    • 78751560396 scopus 로고    scopus 로고
    • High-Throughput 3D Spheroid Culture and Drug Testing Using a 384 Hanging Drop Array
    • Tung, Y.-C.; Hsiao, A. Y.; Allen, S. G.; Torisawa, Y.-S.; Ho, M.; Takayama, S. High-Throughput 3D Spheroid Culture and Drug Testing Using a 384 Hanging Drop Array Analyst 2011, 136, 473-478
    • (2011) Analyst , vol.136 , pp. 473-478
    • Tung, Y.-C.1    Hsiao, A.Y.2    Allen, S.G.3    Torisawa, Y.-S.4    Ho, M.5    Takayama, S.6
  • 7
    • 84861460487 scopus 로고    scopus 로고
    • Microring Structures Stabilize Microdroplets to Enable Long Term Spheroid Culture in 384 Hanging Drop Array Plates
    • Hsiao, A.; Tung, Y.-C.; Kuo, C.-H.; Mosadegh, B.; Bedenis, R.; Pienta, K.; Takayama, S. Microring Structures Stabilize Microdroplets to Enable Long Term Spheroid Culture in 384 Hanging Drop Array Plates Biomed. Microdevices 2012, 14, 313-323
    • (2012) Biomed. Microdevices , vol.14 , pp. 313-323
    • Hsiao, A.1    Tung, Y.-C.2    Kuo, C.-H.3    Mosadegh, B.4    Bedenis, R.5    Pienta, K.6    Takayama, S.7
  • 8
    • 84896305360 scopus 로고    scopus 로고
    • Transfer, Imaging, and Analysis Plate for Facile Handling of 384 Hanging Drop 3D Tissue Spheroids
    • Cavnar, S. P.; Salomonsson, E.; Luker, K. E.; Luker, G. D.; Takayama, S. Transfer, Imaging, and Analysis Plate for Facile Handling of 384 Hanging Drop 3D Tissue Spheroids J. Lab. Autom. 2014, 19, 208-214
    • (2014) J. Lab. Autom. , vol.19 , pp. 208-214
    • Cavnar, S.P.1    Salomonsson, E.2    Luker, K.E.3    Luker, G.D.4    Takayama, S.5
  • 9
    • 77649213213 scopus 로고    scopus 로고
    • Integration Column: Microwell Arrays for Mammalian Cell Culture
    • Charnley, M.; Textor, M.; Khademhosseini, A.; Lutolf, M. Integration Column: Microwell Arrays for Mammalian Cell Culture Integr. Biol. 2009, 1, 625-634
    • (2009) Integr. Biol. , vol.1 , pp. 625-634
    • Charnley, M.1    Textor, M.2    Khademhosseini, A.3    Lutolf, M.4
  • 10
    • 84879607828 scopus 로고    scopus 로고
    • Surface Tension-Mediated, Concave-Microwell Arrays for Large-Scale, Simultaneous Production of Homogeneously Sized Embryoid Bodies
    • Jeong, G. S.; Song, J. H.; Kang, A. R.; Jun, Y.; Kim, J. H.; Chang, J. Y.; Lee, S.-H. Surface Tension-Mediated, Concave-Microwell Arrays for Large-Scale, Simultaneous Production of Homogeneously Sized Embryoid Bodies Adv. Healthc. Mater. 2013, 2, 119-125
    • (2013) Adv. Healthc. Mater. , vol.2 , pp. 119-125
    • Jeong, G.S.1    Song, J.H.2    Kang, A.R.3    Jun, Y.4    Kim, J.H.5    Chang, J.Y.6    Lee, S.-H.7
  • 12
    • 79952154318 scopus 로고    scopus 로고
    • Diffusion-Mediated in Situ Alginate Encapsulation of Cell Spheroids using Microscale Concave Well and Nanoporous Membrane
    • Lee, K. H.; No, D. Y.; Kim, S.-H.; Ryoo, J. H.; Wong, S. F.; Lee, S.-H. Diffusion-Mediated In Situ Alginate Encapsulation of Cell Spheroids using Microscale Concave Well and Nanoporous Membrane Lab Chip 2011, 11, 1168-1173
    • (2011) Lab Chip , vol.11 , pp. 1168-1173
    • Lee, K.H.1    No, D.Y.2    Kim, S.-H.3    Ryoo, J.H.4    Wong, S.F.5    Lee, S.-H.6
  • 13
    • 80052351691 scopus 로고    scopus 로고
    • Concave Microwell Based Size-Controllable Hepatosphere as a Three-Dimensional Liver Tissue Model
    • Wong, S. F.; No, D. Y.; Choi, Y. Y.; Kim, D. S.; Chung, B. G.; Lee, S.-H. Concave Microwell Based Size-Controllable Hepatosphere as a Three-Dimensional Liver Tissue Model Biomaterials 2011, 32, 8087-8096
    • (2011) Biomaterials , vol.32 , pp. 8087-8096
    • Wong, S.F.1    No, D.Y.2    Choi, Y.Y.3    Kim, D.S.4    Chung, B.G.5    Lee, S.-H.6
  • 14
    • 84883810070 scopus 로고    scopus 로고
    • Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model
    • Yeon, S.-E.; No, D. Y.; Lee, S.-H.; Nam, S. W.; Oh, I.-H.; Lee, J.; Kuh, H.-J. Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model PLoS One 2013, 8, e73345
    • (2013) PLoS One , vol.8 , pp. 73345
    • Yeon, S.-E.1    No, D.Y.2    Lee, S.-H.3    Nam, S.W.4    Oh, I.-H.5    Lee, J.6    Kuh, H.-J.7
  • 16
    • 79957659271 scopus 로고    scopus 로고
    • Mechanics of Micromilling with Round Edge Tools
    • Altintas, Y.; Jin, X. Mechanics of Micromilling with Round Edge Tools CIRP Ann. Manuf. Technol. 2011, 60, 77-80
    • (2011) CIRP Ann. Manuf. Technol. , vol.60 , pp. 77-80
    • Altintas, Y.1    Jin, X.2
  • 18
    • 73449143825 scopus 로고    scopus 로고
    • Recent Developments in PDMS Surface Modification for Microfluidic Devices
    • Zhou, J.; Ellis, A. V.; Voelcker, N. H. Recent Developments in PDMS Surface Modification for Microfluidic Devices Electrophoresis 2010, 31, 2-16
    • (2010) Electrophoresis , vol.31 , pp. 2-16
    • Zhou, J.1    Ellis, A.V.2    Voelcker, N.H.3
  • 19
    • 33646577847 scopus 로고    scopus 로고
    • Simple Surface Treatments to Modify Protein Adsorption and Cell Attachment Properties within a Poly(dimethylsiloxane) Microbioreactor
    • Boxshall, K.; Wu, M.-H.; Cui, Z.; Cui, Z.; Watts, J. F.; Baker, M. A. Simple Surface Treatments to Modify Protein Adsorption and Cell Attachment Properties within a Poly(dimethylsiloxane) Microbioreactor Surf. Interface Anal. 2006, 38, 198-201
    • (2006) Surf. Interface Anal. , vol.38 , pp. 198-201
    • Boxshall, K.1    Wu, M.-H.2    Cui, Z.3    Cui, Z.4    Watts, J.F.5    Baker, M.A.6
  • 20
    • 58449109224 scopus 로고    scopus 로고
    • Simple Poly(dimethylsiloxane) Surface Modification to Control Cell Adhesion
    • Wu, M.-H. Simple Poly(dimethylsiloxane) Surface Modification to Control Cell Adhesion Surf. Interface Anal. 2009, 41, 11-16
    • (2009) Surf. Interface Anal. , vol.41 , pp. 11-16
    • Wu, M.-H.1
  • 22
    • 27244432019 scopus 로고    scopus 로고
    • Single Cell Manipulation, Analytics, and Label-Free Protein Detection in Microfluidic Devices for Systems Nanobiology
    • Hellmich, W.; Pelargus, C.; Leffhalm, K.; Ros, A.; Anselmetti, D. Single Cell Manipulation, Analytics, and Label-Free Protein Detection in Microfluidic Devices for Systems Nanobiology Electrophoresis 2005, 26, 3689-3696
    • (2005) Electrophoresis , vol.26 , pp. 3689-3696
    • Hellmich, W.1    Pelargus, C.2    Leffhalm, K.3    Ros, A.4    Anselmetti, D.5
  • 24
    • 69249203894 scopus 로고    scopus 로고
    • Surface Molecular Property Modifications for Poly(dimethylsiloxane) (PDMS) Based Microfluidic Devices
    • Wong, I.; Ho, C.-M. Surface Molecular Property Modifications for Poly(dimethylsiloxane) (PDMS) Based Microfluidic Devices Microfluid. Nanofluid. 2009, 7, 291-306
    • (2009) Microfluid. Nanofluid. , vol.7 , pp. 291-306
    • Wong, I.1    Ho, C.-M.2
  • 25
    • 4644290645 scopus 로고    scopus 로고
    • Separation of Proteins on Surface-Modified Poly(dimethylsiloxane) Microfluidic Devices
    • Dou, Y.-H.; Bao, N.; Xu, J.-J.; Meng, F.; Chen, H.-Y. Separation of Proteins on Surface-Modified Poly(dimethylsiloxane) Microfluidic Devices Electrophoresis 2004, 25, 3024-3031
    • (2004) Electrophoresis , vol.25 , pp. 3024-3031
    • Dou, Y.-H.1    Bao, N.2    Xu, J.-J.3    Meng, F.4    Chen, H.-Y.5
  • 26
    • 33746254936 scopus 로고    scopus 로고
    • A Stable PEO-Tethered PDMS Surface having Controllable Wetting Property by a Swelling-Deswelling Process
    • Yu, K.; Han, Y. A Stable PEO-Tethered PDMS Surface having Controllable Wetting Property by a Swelling-Deswelling Process Soft Matter 2006, 2, 705-709
    • (2006) Soft Matter , vol.2 , pp. 705-709
    • Yu, K.1    Han, Y.2
  • 27
    • 52649180513 scopus 로고    scopus 로고
    • Reactive Epoxy-Functionalized Thin Films by a Pulsed Plasma Polymerization Process
    • Thierry, B.; Jasieniak, M.; de Smet, L. C. P. M.; Vasilev, K.; Griesser, H. J. Reactive Epoxy-Functionalized Thin Films by a Pulsed Plasma Polymerization Process Langmuir 2008, 24, 10187-10195
    • (2008) Langmuir , vol.24 , pp. 10187-10195
    • Thierry, B.1    Jasieniak, M.2    De Smet, L.C.P.M.3    Vasilev, K.4    Griesser, H.J.5
  • 28
    • 0032637821 scopus 로고    scopus 로고
    • The Deposition of Anti-adhesive Ultra-thin Teflon-like Films and Their Interaction with Polymers during Hot Embossing
    • Jaszewski, R. W.; Schift, H.; Schnyder, B.; Schneuwly, A.; Gröning, P. The Deposition of Anti-adhesive Ultra-thin Teflon-like Films and Their Interaction with Polymers during Hot Embossing Appl. Surf. Sci. 1999, 143, 301-308
    • (1999) Appl. Surf. Sci. , vol.143 , pp. 301-308
    • Jaszewski, R.W.1    Schift, H.2    Schnyder, B.3    Schneuwly, A.4    Gröning, P.5
  • 29
    • 33846122971 scopus 로고    scopus 로고
    • Design of Experiment for Optimization of Plasma-Polymerized Octafluorocyclobutane Coating on Very High Aspect Ratio Silicon Molds
    • Yeo, L. P.; Yan, Y. H.; Lam, Y. C.; Chan-Park, M. B. Design of Experiment for Optimization of Plasma-Polymerized Octafluorocyclobutane Coating on Very High Aspect Ratio Silicon Molds Langmuir 2006, 22, 10196-10203
    • (2006) Langmuir , vol.22 , pp. 10196-10203
    • Yeo, L.P.1    Yan, Y.H.2    Lam, Y.C.3    Chan-Park, M.B.4
  • 30
    • 79952423133 scopus 로고    scopus 로고
    • Surface Modification of 2D/3D SU-8 Patterns with a Swelling-Deswelling Method
    • Kim, H.-N.; Kang, J.-H.; Jin, W.-M.; Moon, J. H. Surface Modification of 2D/3D SU-8 Patterns with a Swelling-Deswelling Method Soft Matter 2011, 7, 2989-2993
    • (2011) Soft Matter , vol.7 , pp. 2989-2993
    • Kim, H.-N.1    Kang, J.-H.2    Jin, W.-M.3    Moon, J.H.4
  • 31
    • 66149148925 scopus 로고    scopus 로고
    • Surface Modification of PDMS by Gradient-Induced Migration of Embedded Pluronic
    • Wu, Z.; Hjort, K. Surface Modification of PDMS by Gradient-Induced Migration of Embedded Pluronic Lab Chip 2009, 9, 1500-1503
    • (2009) Lab Chip , vol.9 , pp. 1500-1503
    • Wu, Z.1    Hjort, K.2
  • 32
    • 33746634270 scopus 로고    scopus 로고
    • Three-dimensional Culture Regulates Raf-1 Expression to Modulate Fibronectin Matrix Assembly
    • Winters, B. S.; Raj, B. K. M.; Robinson, E. E.; Foty, R. A.; Corbett, S. A. Three-dimensional Culture Regulates Raf-1 Expression to Modulate Fibronectin Matrix Assembly Mol. Biol. Cell 2006, 17, 3386-3396
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3386-3396
    • Winters, B.S.1    Raj, B.K.M.2    Robinson, E.E.3    Foty, R.A.4    Corbett, S.A.5
  • 34
    • 84855837427 scopus 로고    scopus 로고
    • Curcumin Nanoformulations: A Future Nanomedicine for Cancer
    • Yallapu, M. M.; Jaggi, M.; Chauhan, S. C. Curcumin Nanoformulations: A Future Nanomedicine for Cancer Drug Discovery Today 2012, 17, 71-80
    • (2012) Drug Discovery Today , vol.17 , pp. 71-80
    • Yallapu, M.M.1    Jaggi, M.2    Chauhan, S.C.3
  • 36
    • 74249083465 scopus 로고    scopus 로고
    • Curcumin-Induced Apoptosis in Ovarian Carcinoma Cells is P53-Independent and Involves P38 Mitogen-Activated Protein Kinase Activation and Downregulation of Bcl-2 and Survivin Expression and Akt Signaling
    • Watson, J. L.; Greenshields, A.; Hill, R.; Hilchie, A.; Lee, P. W.; Giacomantonio, C. A.; Hoskin, D. W. Curcumin-Induced Apoptosis in Ovarian Carcinoma Cells is P53-Independent and Involves P38 Mitogen-Activated Protein Kinase Activation and Downregulation of Bcl-2 and Survivin Expression and Akt Signaling Mol. Carcinogen. 2010, 49, 13-24
    • (2010) Mol. Carcinogen. , vol.49 , pp. 13-24
    • Watson, J.L.1    Greenshields, A.2    Hill, R.3    Hilchie, A.4    Lee, P.W.5    Giacomantonio, C.A.6    Hoskin, D.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.