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Volumn 30, Issue 3, 2014, Pages 524-534

Bone marrow stromal cells as a therapeutic treatment for ischemic stroke

Author keywords

administration method; bone marrow stromal cell; cerebral ischemia; neuroprotection; transplantation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CXCR4; CONNEXIN 43; FIBROBLAST GROWTH FACTOR 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; NEUROMODULIN; PLACENTAL GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN; VASCULOTROPIN;

EID: 84902386203     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1431-y     Document Type: Review
Times cited : (31)

References (79)
  • 2
    • 0034809239 scopus 로고    scopus 로고
    • In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP
    • DOI 10.1006/bbrc.2001.4570
    • Deng W, Obrocka M, Fischer I, Prockop DJ. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 2001, 282: 148-152. (Pubitemid 32924357)
    • (2001) Biochemical and Biophysical Research Communications , vol.282 , Issue.1 , pp. 148-152
    • Deng, W.1    Obrocka, M.2    Fischer, I.3    Prockop, D.J.4
  • 3
    • 0034737742 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase
    • DOI 10.1074/jbc.275.13.9645
    • Jaiswal RK, Jaiswal N, Bruder SP, Mbalaviele G, Marshak DR, Pittenger MF. Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase. J Biol Chem 2000, 275: 9645-9652. (Pubitemid 30185197)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9645-9652
    • Jaiswal, R.K.1    Jaiswal, N.2    Bruder, S.P.3    Mbalaviele, G.4    Marshak, D.R.5    Pittenger, M.F.6
  • 5
    • 0035954362 scopus 로고    scopus 로고
    • Treatment of stroke in rat with intracarotid administration of marrow stromal cells
    • Li Y, Chen J, Wang L, Lu M, Chopp M. Treatment of stroke in rat with intracarotid administration of marrow stromal cells. Neurology 2001, 56: 1666-1672. (Pubitemid 32574564)
    • (2001) Neurology , vol.56 , Issue.12 , pp. 1666-1672
    • Li, Y.1    Chen, J.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 6
    • 0037106144 scopus 로고    scopus 로고
    • Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis
    • DOI 10.1002/jnr.10365
    • Woodbury D, Reynolds K, Black IB. Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis. J Neurosci Res 2002, 69: 908-917. (Pubitemid 34984707)
    • (2002) Journal of Neuroscience Research , vol.69 , Issue.6 , pp. 908-917
    • Woodbury, D.1    Reynolds, K.2    Black, I.B.3
  • 7
    • 0034856553 scopus 로고    scopus 로고
    • Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering
    • DOI 10.1046/j.1525-1594.2001.025003187.x
    • Fukuda K. Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif Organs 2001, 25: 187-193. (Pubitemid 32852966)
    • (2001) Artificial Organs , vol.25 , Issue.3 , pp. 187-193
    • Fukuda, K.1
  • 9
    • 50849090271 scopus 로고    scopus 로고
    • Transplanted bone marrow stromal cells migrate, differentiate and improve motor function in rats with experimentally induced cerebral stroke
    • Chen JR, Cheng GY, Sheu CC, Tseng GF, Wang TJ, Huang YS. Transplanted bone marrow stromal cells migrate, differentiate and improve motor function in rats with experimentally induced cerebral stroke. J Anat 2008, 213: 249-258.
    • (2008) J Anat , vol.213 , pp. 249-258
    • Chen, J.R.1    Cheng, G.Y.2    Sheu, C.C.3    Tseng, G.F.4    Wang, T.J.5    Huang, Y.S.6
  • 10
    • 79960979925 scopus 로고    scopus 로고
    • BMSC and CoQ10 improve behavioural recovery and histological outcome in rat model of Parkinson's disease
    • Nezhadi A, Ghazi F, Rassoli H, Bakhtiari M, Ataiy Z, Soleimani S, et al. BMSC and CoQ10 improve behavioural recovery and histological outcome in rat model of Parkinson's disease. Pathophysiology 2011, 18: 317-324.
    • (2011) Pathophysiology , vol.18 , pp. 317-324
    • Nezhadi, A.1    Ghazi, F.2    Rassoli, H.3    Bakhtiari, M.4    Ataiy, Z.5    Soleimani, S.6
  • 11
    • 77649092027 scopus 로고    scopus 로고
    • Comparison of bone marrow stromal cells derived from stroke and normal rats for stroke treatment
    • Zacharek A, Shehadah A, Chen J, Cui X, Roberts C, Lu M, et al. Comparison of bone marrow stromal cells derived from stroke and normal rats for stroke treatment. Stroke 2010, 41: 524-530.
    • (2010) Stroke , vol.41 , pp. 524-530
    • Zacharek, A.1    Shehadah, A.2    Chen, J.3    Cui, X.4    Roberts, C.5    Lu, M.6
  • 12
    • 84867723350 scopus 로고    scopus 로고
    • Bone marrow stromal cells enhance the angiogenesis in ischaemic cortex after stroke: Involvement of notch signalling
    • Guo F, Lv S, Lou Y, Tu W, Liao W, Wang Y, et al. Bone marrow stromal cells enhance the angiogenesis in ischaemic cortex after stroke: involvement of notch signalling. Cell Biol Int 2012, 36: 997-1004.
    • (2012) Cell Biol Int , vol.36 , pp. 997-1004
    • Guo, F.1    Lv, S.2    Lou, Y.3    Tu, W.4    Liao, W.5    Wang, Y.6
  • 13
    • 51949107296 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
    • Yoo SW, Kim SS, Lee SY, Lee HS, Kim HS, Lee YD, et al. Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model. Exp Mol Med 2008, 40: 387-397.
    • (2008) Exp Mol Med , vol.40 , pp. 387-397
    • Yoo, S.W.1    Kim, S.S.2    Lee, S.Y.3    Lee, H.S.4    Kim, H.S.5    Lee, Y.D.6
  • 14
    • 0033844402 scopus 로고    scopus 로고
    • Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice
    • Li Y, Chopp M, Chen J, Wang L, Gautam SC, Xu YX, et al. Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice. J Cereb Blood Flow Metab 2000, 20: 1311-1319.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1311-1319
    • Li, Y.1    Chopp, M.2    Chen, J.3    Wang, L.4    Gautam, S.C.5    Xu, Y.X.6
  • 15
    • 2342566505 scopus 로고    scopus 로고
    • Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats
    • DOI 10.1016/j.brainres.2004.02.072, PII S0006899304004275
    • Borlongan CV, Lind JG, Dillon-Carter O, Yu G, Hadman M, Cheng C, et al. Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res 2004, 1010: 108-116. (Pubitemid 38569858)
    • (2004) Brain Research , vol.1010 , Issue.1-2 , pp. 108-116
    • Borlongan, C.V.1    Lind, J.G.2    Dillon-Carter, O.3    Yu, G.4    Hadman, M.5    Cheng, C.6    Carroll, J.7    Hess, D.C.8
  • 16
    • 29744441582 scopus 로고    scopus 로고
    • Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke
    • DOI 10.1016/j.neuroscience.2005.08.092, PII S0306452205009875
    • Shen LH, Li Y, Chen J, Zhang J, Vanguri P, Borneman J, et al. Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke. Neuroscience 2006, 137: 393-399. (Pubitemid 43031506)
    • (2006) Neuroscience , vol.137 , Issue.2 , pp. 393-399
    • Shen, L.H.1    Li, Y.2    Chen, J.3    Zhang, J.4    Vanguri, P.5    Borneman, J.6    Chopp, M.7
  • 17
    • 84866013566 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow stromal cells ameliorates tissue plasminogen activator-induced brain damage after cerebral ischemia in mice detected by in vivo and ex vivo optical imaging
    • Liu N, Deguchi K, Yamashita T, Liu W, Ikeda Y, Abe K. Intracerebral transplantation of bone marrow stromal cells ameliorates tissue plasminogen activator-induced brain damage after cerebral ischemia in mice detected by in vivo and ex vivo optical imaging. J Neurosci Res 2012, 90: 2086-2093.
    • (2012) J Neurosci Res , vol.90 , pp. 2086-2093
    • Liu, N.1    Deguchi, K.2    Yamashita, T.3    Liu, W.4    Ikeda, Y.5    Abe, K.6
  • 18
    • 68549098095 scopus 로고    scopus 로고
    • Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cells
    • Liu N, Chen R, Du H, Wang J, Zhang Y, Wen J. Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cells. Cell Mol Immunol 2009, 6: 207-213.
    • (2009) Cell Mol Immunol , vol.6 , pp. 207-213
    • Liu, N.1    Chen, R.2    Du, H.3    Wang, J.4    Zhang, Y.5    Wen, J.6
  • 19
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • DOI 10.1006/exnr.2001.7853
    • Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 2002, 174: 11-20. (Pubitemid 34218904)
    • (2002) Experimental Neurology , vol.174 , Issue.1 , pp. 11-20
    • Zhao, L.-R.1    Duan, W.-M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6
  • 20
    • 2442425347 scopus 로고    scopus 로고
    • Intracerebral Xenotransplantation of GFP Mouse Bone Marrow Stromal Cells in Intact and Stroke Rat Brain: Graft Survival and Immunologic Response
    • Irons H, Lind JG, Wakade CG, Yu G, Hadman M, Carroll J, et al. Intracerebral xenotransplantation of GFP mouse bone marrow stromal cells in intact and stroke rat brain: graft survival and immunologic response. Cell Transplant 2004, 13: 283-294. (Pubitemid 38620970)
    • (2004) Cell Transplantation , vol.13 , Issue.3 , pp. 283-294
    • Irons, H.1    Lind, J.G.2    Wakade, C.G.3    Yu, G.4    Hadman, M.5    Carroll, J.6    Hess, D.C.7    Borlongan, C.V.8
  • 21
    • 3543083969 scopus 로고    scopus 로고
    • In vivo tracking of bone marrow stromal cells transplanted into mice cerebral infarct by fluorescence optical imaging
    • DOI 10.1016/j.brainresprot.2004.04.004, PII S1385299X04000431
    • Shichinohe H, Kuroda S, Lee JB, Nishimura G, Yano S, Seki T, et al. In vivo tracking of bone marrow stromal cells transplanted into mice cerebral infarct by fluorescence optical imaging. Brain Res Brain Res Protoc 2004, 13: 166-175. (Pubitemid 39030777)
    • (2004) Brain Research Protocols , vol.13 , Issue.3 , pp. 166-175
    • Shichinohe, H.1    Kuroda, S.2    Lee, J.-B.3    Nishimura, G.4    Yano, S.5    Seki, T.6    Ikeda, J.7    Tamura, M.8    Iwasaki, Y.9
  • 22
    • 0035881367 scopus 로고    scopus 로고
    • Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats
    • DOI 10.1016/S0022-510X(01)00557-3, PII S0022510X01005573
    • Chen J, Li Y, Wang L, Lu M, Zhang X, Chopp M. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats. J Neurol Sci 2001, 189: 49-57. (Pubitemid 32776649)
    • (2001) Journal of the Neurological Sciences , vol.189 , Issue.1-2 , pp. 49-57
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Zhang, X.5    Chopp, M.6
  • 23
    • 84872032344 scopus 로고    scopus 로고
    • Bone marrow stromal cell transplantation enhances recovery of local glucose metabolism after cerebral infarction in rats: A serial 18F-FDG PET study
    • Miyamoto M, Kuroda S, Zhao S, Magota K, Shichinohe H, Houkin K, et al. Bone marrow stromal cell transplantation enhances recovery of local glucose metabolism after cerebral infarction in rats: a serial 18F-FDG PET study. J Nucl Med 2013, 54: 145-150.
    • (2013) J Nucl Med , vol.54 , pp. 145-150
    • Miyamoto, M.1    Kuroda, S.2    Zhao, S.3    Magota, K.4    Shichinohe, H.5    Houkin, K.6
  • 24
    • 33746001384 scopus 로고    scopus 로고
    • Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats
    • DOI 10.1016/j.neuroscience.2006.04.054, PII S0306452206004982
    • Zhang C, Li Y, Chen J, Gao Q, Zacharek A, Kapke A, et al. Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats. Neuroscience 2006, 141: 687-695. (Pubitemid 44066656)
    • (2006) Neuroscience , vol.141 , Issue.2 , pp. 687-695
    • Zhang, C.1    Li, Y.2    Chen, J.3    Gao, Q.4    Zacharek, A.5    Kapke, A.6    Chopp, M.7
  • 25
    • 58849166174 scopus 로고    scopus 로고
    • Early transient presence of implanted bone marrow stem cells reduces lesion size after cerebral ischaemia in adult rats
    • Keimpema E, Fokkens MR, Nagy Z, Agoston V, Luiten PG, Nyakas C, et al. Early transient presence of implanted bone marrow stem cells reduces lesion size after cerebral ischaemia in adult rats. Neuropathol Appl Neurobiol 2009, 35: 89-102.
    • (2009) Neuropathol Appl Neurobiol , vol.35 , pp. 89-102
    • Keimpema, E.1    Fokkens, M.R.2    Nagy, Z.3    Agoston, V.4    Luiten, P.G.5    Nyakas, C.6
  • 26
    • 0035075998 scopus 로고    scopus 로고
    • Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001, 32: 1005-1011. (Pubitemid 32285175)
    • (2001) Stroke , vol.32 , Issue.4 , pp. 1005-1011
    • Chen, J.1    Li, Y.2    Wang, L.3    Zhang, Z.4    Lu, D.5    Lu, M.6    Chopp, M.7
  • 27
    • 0036323779 scopus 로고    scopus 로고
    • Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture
    • DOI 10.1016/S0301-472X(02)00829-9, PII S0301472X02008299
    • Wang L, Li Y, Chen J, Gautam SC, Zhang Z, Lu M, et al. Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture. Exp Hematol 2002, 30: 831-836. (Pubitemid 34831705)
    • (2002) Experimental Hematology , vol.30 , Issue.7 , pp. 831-836
    • Wang, L.1    Li, Y.2    Chen, J.3    Gautam, S.C.4    Zhang, Z.5    Lu, M.6    Chopp, M.7
  • 28
    • 0037418936 scopus 로고    scopus 로고
    • Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
    • DOI 10.1161/01.RES.0000063425.51108.8D
    • Chen J, Zhang ZG, Li Y, Wang L, Xu YX, Gautam SC, et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003, 92: 692-699. (Pubitemid 36417705)
    • (2003) Circulation Research , vol.92 , Issue.6 , pp. 692-699
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3    Wang, L.4    Xu, Y.X.5    Gautam, S.C.6    Lu, M.7    Zhu, Z.8    Chopp, M.9
  • 29
    • 1642319466 scopus 로고    scopus 로고
    • Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis
    • DOI 10.1016/j.brainres.2003.11.080, PII S0006899304001167
    • Chen J, Li Y, Zhang R, Katakowski M, Gautam SC, Xu Y, et al. Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis. Brain Res 2004, 1005: 21-28. (Pubitemid 38388396)
    • (2004) Brain Research , vol.1005 , Issue.1-2 , pp. 21-28
    • Chen, J.1    Li, Y.2    Zhang, R.3    Katakowski, M.4    Gautam, S.C.5    Xu, Y.6    Lu, M.7    Zhang, Z.8    Chopp, M.9
  • 30
    • 9444267155 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells
    • DOI 10.1016/j.brainres.2004.09.061, PII S0006899304015719
    • Zhang J, Li Y, Chen J, Yang M, Katakowski M, Lu M, et al. Expression of insulin-like growth factor 1 and receptor in ischemic rats treated with human marrow stromal cells. Brain Res 2004, 1030: 19-27. (Pubitemid 39563824)
    • (2004) Brain Research , vol.1030 , Issue.1 , pp. 19-27
    • Zhang, J.1    Li, Y.2    Chen, J.3    Yang, M.4    Katakowski, M.5    Lu, M.6    Chopp, M.7
  • 31
    • 84887117028 scopus 로고    scopus 로고
    • Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats
    • Xin H, Li Y, Cui Y, Yang JJ, Zhang ZG, Chopp M. Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats. J Cereb Blood Flow Metab 2013, 33(11): 1711-1715.
    • (2013) J Cereb Blood Flow Metab , vol.33 , Issue.11 , pp. 1711-1715
    • Xin, H.1    Li, Y.2    Cui, Y.3    Yang, J.J.4    Zhang, Z.G.5    Chopp, M.6
  • 32
    • 0041336932 scopus 로고    scopus 로고
    • Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat
    • DOI 10.1002/jnr.10691
    • Chen J, Li Y, Katakowski M, Chen X, Wang L, Lu D, et al. Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat. J Neurosci Res 2003, 73: 778-786. (Pubitemid 37071731)
    • (2003) Journal of Neuroscience Research , vol.73 , Issue.6 , pp. 778-786
    • Chen, J.1    Li, Y.2    Katakowski, M.3    Chen, X.4    Wang, L.5    Lu, D.6    Lu, M.7    Gautam, S.C.8    Chopp, M.9
  • 33
    • 37549062215 scopus 로고    scopus 로고
    • Intravenous administration of bone marrow stromal cells increases survivin and Bcl-2 protein expression and improves sensorimotor function following ischemia in rats
    • Okazaki T, Magaki T, Takeda M, Kajiwara Y, Hanaya R, Sugiyama K, et al. Intravenous administration of bone marrow stromal cells increases survivin and Bcl-2 protein expression and improves sensorimotor function following ischemia in rats. Neurosci Lett 2008, 430: 109-114.
    • (2008) Neurosci Lett , vol.430 , pp. 109-114
    • Okazaki, T.1    Magaki, T.2    Takeda, M.3    Kajiwara, Y.4    Hanaya, R.5    Sugiyama, K.6
  • 34
    • 73149097202 scopus 로고    scopus 로고
    • Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia
    • Zheng W, Honmou O, Miyata K, Harada K, Suzuki J, Liu H, et al. Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia. Brain Res 2010, 1310: 8-16.
    • (2010) Brain Res , vol.1310 , pp. 8-16
    • Zheng, W.1    Honmou, O.2    Miyata, K.3    Harada, K.4    Suzuki, J.5    Liu, H.6
  • 35
    • 84875813306 scopus 로고    scopus 로고
    • Timing and cell dose determine therapeutic effects of bone marrow stromal cell transplantation in rat model of cerebral infarct
    • Kawabori M, Kuroda S, Ito M, Shichinohe H, Houkin K, Kuge Y, et al. Timing and cell dose determine therapeutic effects of bone marrow stromal cell transplantation in rat model of cerebral infarct. Neuropathology 2013, 33: 140-148.
    • (2013) Neuropathology , vol.33 , pp. 140-148
    • Kawabori, M.1    Kuroda, S.2    Ito, M.3    Shichinohe, H.4    Houkin, K.5    Kuge, Y.6
  • 36
    • 80052648782 scopus 로고    scopus 로고
    • Motor-evoked potential confirmation of functional improvement by transplanted bone marrow mesenchymal stem cell in the ischemic rat brain
    • Jang DK, Park SI, Han YM, Jang KS, Park MS, Chung YA, et al. Motor-evoked potential confirmation of functional improvement by transplanted bone marrow mesenchymal stem cell in the ischemic rat brain. J Biomed Biotechnol 2011, 2011: 238409.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 238409
    • Jang, D.K.1    Park, S.I.2    Han, Y.M.3    Jang, K.S.4    Park, M.S.5    Chung, Y.A.6
  • 37
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss TM, Andres RH, Steinberg GK. Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis 2010, 37: 275-283.
    • (2010) Neurobiol Dis , vol.37 , pp. 275-283
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 38
    • 44349145552 scopus 로고    scopus 로고
    • Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats
    • DOI 10.3727/000000007783472435
    • Wu J, Sun Z, Sun HS, Weisel RD, Keating A, Li ZH, et al. Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats. Cell Transplant 2008, 16: 993-1005. (Pubitemid 351732841)
    • (2008) Cell Transplantation , vol.16 , Issue.10 , pp. 993-1005
    • Wu, J.1    Sun, Z.2    Sun, H.-S.3    Wu, J.4    Weisel, R.D.5    Keating, A.6    Li, Z.-H.7    Feng, Z.-P.8    Li, R.-K.9
  • 39
    • 66249096305 scopus 로고    scopus 로고
    • Pulmonary passage is a major obstacle for intravenous stem cell delivery: The pulmonary first-pass effect
    • Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI, et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev 2009, 18: 683-692.
    • (2009) Stem Cells Dev , vol.18 , pp. 683-692
    • Fischer, U.M.1    Harting, M.T.2    Jimenez, F.3    Monzon-Posadas, W.O.4    Xue, H.5    Savitz, S.I.6
  • 40
    • 33745187411 scopus 로고    scopus 로고
    • Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat
    • Honma T, Honmou O, Iihoshi S, Harada K, Houkin K, Hamada H, et al. Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp Neurol 2006, 199: 56-66.
    • (2006) Exp Neurol , vol.199 , pp. 56-66
    • Honma, T.1    Honmou, O.2    Iihoshi, S.3    Harada, K.4    Houkin, K.5    Hamada, H.6
  • 41
    • 33645739092 scopus 로고    scopus 로고
    • Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats
    • Li Y, McIntosh K, Chen J, Zhang C, Gao Q, Borneman J, et al. Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats. Exp Neurol 2006, 198: 313-325.
    • (2006) Exp Neurol , vol.198 , pp. 313-325
    • Li, Y.1    McIntosh, K.2    Chen, J.3    Zhang, C.4    Gao, Q.5    Borneman, J.6
  • 43
    • 51649129232 scopus 로고    scopus 로고
    • Mesenchymal stem cells transplantation could be beneficial for treatment of experimental ischemic stroke in rats
    • Pavlichenko N, Sokolova I, Vijde S, Shvedova E, Alexandrov G, Krouglyakov P, et al. Mesenchymal stem cells transplantation could be beneficial for treatment of experimental ischemic stroke in rats. Brain Res 2008, 1233: 203-213.
    • (2008) Brain Res , vol.1233 , pp. 203-213
    • Pavlichenko, N.1    Sokolova, I.2    Vijde, S.3    Shvedova, E.4    Alexandrov, G.5    Krouglyakov, P.6
  • 44
    • 53049098859 scopus 로고    scopus 로고
    • Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats
    • Omori Y, Honmou O, Harada K, Suzuki J, Houkin K, Kocsis JD. Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats. Brain Res 2008, 1236: 30-38.
    • (2008) Brain Res , vol.1236 , pp. 30-38
    • Omori, Y.1    Honmou, O.2    Harada, K.3    Suzuki, J.4    Houkin, K.5    Kocsis, J.D.6
  • 46
    • 33644684038 scopus 로고    scopus 로고
    • Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in rats
    • Ikeda N, Nonoguchi N, Zhao MZ, Watanabe T, Kajimoto Y, Furutama D, et al. Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in rats. Stroke 2005, 36: 2725-2730.
    • (2005) Stroke , vol.36 , pp. 2725-2730
    • Ikeda, N.1    Nonoguchi, N.2    Zhao, M.Z.3    Watanabe, T.4    Kajimoto, Y.5    Furutama, D.6
  • 48
    • 65049083651 scopus 로고    scopus 로고
    • Synergistic effects of granulocyte-colony stimulating factor on bone marrow stromal cell transplantation for mice cerebral infarct
    • Hokari M, Kuroda S, Chiba Y, Maruichi K, Iwasaki Y. Synergistic effects of granulocyte-colony stimulating factor on bone marrow stromal cell transplantation for mice cerebral infarct. Cytokine 2009, 46: 260-266.
    • (2009) Cytokine , vol.46 , pp. 260-266
    • Hokari, M.1    Kuroda, S.2    Chiba, Y.3    Maruichi, K.4    Iwasaki, Y.5
  • 49
    • 26944484409 scopus 로고    scopus 로고
    • I.v. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat
    • DOI 10.1016/j.neuroscience.2005.06.062, PII S0306452205007128
    • Nomura T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005, 136: 161-169. (Pubitemid 41483844)
    • (2005) Neuroscience , vol.136 , Issue.1 , pp. 161-169
    • Nomura, T.1    Honmou, O.2    Harada, K.3    Houkin, K.4    Hamada, H.5    Kocsis, J.D.6
  • 50
    • 33750587812 scopus 로고    scopus 로고
    • Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat
    • DOI 10.1002/jnr.21056
    • Horita Y, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat. J Neurosci Res 2006, 84: 1495-1504. (Pubitemid 44683142)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.7 , pp. 1495-1504
    • Horita, Y.1    Honmou, O.2    Harada, K.3    Houkin, K.4    Hamada, H.5    Kocsis, J.D.6
  • 51
    • 33749455560 scopus 로고    scopus 로고
    • Neuroprotection by PIGF gene-modified human mesenchymal stem cells after cerebral ischaemia
    • DOI 10.1093/brain/awl207
    • Liu H, Honmou O, Harada K, Nakamura K, Houkin K, Hamada H, et al. Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia. Brain 2006, 129: 2734-2745. (Pubitemid 44522106)
    • (2006) Brain , vol.129 , Issue.10 , pp. 2734-2745
    • Liu, H.1    Honmou, O.2    Harada, K.3    Nakamura, K.4    Houkin, K.5    Hamada, H.6    Kocsis, J.D.7
  • 52
    • 38549154182 scopus 로고    scopus 로고
    • Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia
    • DOI 10.1038/sj.jcbfm.9600527, PII 9600527
    • Onda T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD. Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia. J Cereb Blood Flow Metab 2008, 28: 329-340. (Pubitemid 351161284)
    • (2008) Journal of Cerebral Blood Flow and Metabolism , vol.28 , Issue.2 , pp. 329-340
    • Onda, T.1    Honmou, O.2    Harada, K.3    Houkin, K.4    Hamada, H.5    Kocsis, J.D.6
  • 53
    • 33644798952 scopus 로고    scopus 로고
    • Behavioral and histological evaluation of a focal cerebral infarction rat model transplanted with neurons induced from bone marrow stromal cells
    • Mimura T, Dezawa M, Kanno H, Yamamoto I. Behavioral and histological evaluation of a focal cerebral infarction rat model transplanted with neurons induced from bone marrow stromal cells. J Neuropathol Exp Neurol 2005, 64: 1108-1117.
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 1108-1117
    • Mimura, T.1    Dezawa, M.2    Kanno, H.3    Yamamoto, I.4
  • 54
    • 0029101747 scopus 로고
    • Ministrokes in rat barrel cortex
    • Wei L, Rovainen CM, Woolsey TA. Ministrokes in rat barrel cortex. Stroke 1995, 26: 1459-1462.
    • (1995) Stroke , vol.26 , pp. 1459-1462
    • Wei, L.1    Rovainen, C.M.2    Woolsey, T.A.3
  • 55
    • 84886376667 scopus 로고    scopus 로고
    • Restoration of intracortical and thalamocortical circuits after transplantation of bone marrow mesenchymal stem cells into the ischemic brain of mice
    • Song M, Mohamad O, Gu X, Wei L, Yu SP. Restoration of intracortical and thalamocortical circuits after transplantation of bone marrow mesenchymal stem cells into the ischemic brain of mice. Cell Transplant 2013, 22(11): 2001-2015.
    • (2013) Cell Transplant , vol.22 , Issue.11 , pp. 2001-2015
    • Song, M.1    Mohamad, O.2    Gu, X.3    Wei, L.4    Yu, S.P.5
  • 56
    • 84877709953 scopus 로고    scopus 로고
    • Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice
    • Wei N, Yu SP, Gu X, Taylor TM, Song D, Liu XF, et al. Delayed intranasal delivery of hypoxic-preconditioned bone marrow mesenchymal stem cells enhanced cell homing and therapeutic benefits after ischemic stroke in mice. Cell Transplant 2013, 22: 977-991.
    • (2013) Cell Transplant , vol.22 , pp. 977-991
    • Wei, N.1    Yu, S.P.2    Gu, X.3    Taylor, T.M.4    Song, D.5    Liu, X.F.6
  • 57
    • 79957812970 scopus 로고    scopus 로고
    • Transfection of Noggin in bone marrow stromal cells (BMSCs) enhances BMSC-induced functional outcome after stroke in rats
    • Chen C, Cheng Y, Chen J. Transfection of Noggin in bone marrow stromal cells (BMSCs) enhances BMSC-induced functional outcome after stroke in rats. J Neurosci Res 2011, 89: 1194-1202.
    • (2011) J Neurosci Res , vol.89 , pp. 1194-1202
    • Chen, C.1    Cheng, Y.2    Chen, J.3
  • 58
    • 84862832130 scopus 로고    scopus 로고
    • Overexpression of CXCR4 in mesenchymal stem cells promotes migration, neuroprotection and angiogenesis in a rat model of stroke
    • Yu X, Chen D, Zhang Y, Wu X, Huang Z, Zhou H, et al. Overexpression of CXCR4 in mesenchymal stem cells promotes migration, neuroprotection and angiogenesis in a rat model of stroke. J Neurol Sci 2012, 316: 141-149.
    • (2012) J Neurol Sci , vol.316 , pp. 141-149
    • Yu, X.1    Chen, D.2    Zhang, Y.3    Wu, X.4    Huang, Z.5    Zhou, H.6
  • 60
    • 59749103836 scopus 로고    scopus 로고
    • Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia
    • Toyama K, Honmou O, Harada K, Suzuki J, Houkin K, Hamada H, et al. Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia. Exp Neurol 2009, 216: 47-55.
    • (2009) Exp Neurol , vol.216 , pp. 47-55
    • Toyama, K.1    Honmou, O.2    Harada, K.3    Suzuki, J.4    Houkin, K.5    Hamada, H.6
  • 62
    • 78650225880 scopus 로고    scopus 로고
    • Effects of nerve growth factor and Noggin-modified bone marrow stromal cells on stroke in rats
    • Ding J, Cheng Y, Gao S, Chen J. Effects of nerve growth factor and Noggin-modified bone marrow stromal cells on stroke in rats. J Neurosci Res 2011, 89: 222-230.
    • (2011) J Neurosci Res , vol.89 , pp. 222-230
    • Ding, J.1    Cheng, Y.2    Gao, S.3    Chen, J.4
  • 63
    • 79955946614 scopus 로고    scopus 로고
    • Human embryonic stem cell neural differentiation and enhanced cell survival promoted by hypoxic preconditioning
    • Francis KR, Wei L. Human embryonic stem cell neural differentiation and enhanced cell survival promoted by hypoxic preconditioning. Cell Death Dis 2010, 1: e22.
    • (2010) Cell Death Dis , vol.1
    • Francis, K.R.1    Wei, L.2
  • 64
    • 84860834913 scopus 로고    scopus 로고
    • Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats
    • Wei L, Fraser JL, Lu ZY, Hu X, Yu SP. Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats. Neurobiol Dis 2012, 46: 635-645.
    • (2012) Neurobiol Dis , vol.46 , pp. 635-645
    • Wei, L.1    Fraser, J.L.2    Lu, Z.Y.3    Hu, X.4    Yu, S.P.5
  • 65
    • 84863167179 scopus 로고    scopus 로고
    • Roles of chemokine CXCL12 and its receptors in ischemic stroke
    • Wang Y, Huang J, Li Y, Yang GY. Roles of chemokine CXCL12 and its receptors in ischemic stroke. Curr Drug Targets 2012, 13: 166-172.
    • (2012) Curr Drug Targets , vol.13 , pp. 166-172
    • Wang, Y.1    Huang, J.2    Li, Y.3    Yang, G.Y.4
  • 66
    • 39149131038 scopus 로고    scopus 로고
    • SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model
    • Wang Y, Deng Y, Zhou GQ. SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model. Brain Res 2008, 1195: 104-112.
    • (2008) Brain Res , vol.1195 , pp. 104-112
    • Wang, Y.1    Deng, Y.2    Zhou, G.Q.3
  • 67
    • 0037099784 scopus 로고    scopus 로고
    • Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats
    • DOI 10.1016/S0022-510X(02)00075-8, PII S0022510X02000758
    • Chen J, Li Y, Wang L, Lu M, Chopp M. Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats. J Neurol Sci 2002, 199: 17-24. (Pubitemid 34669838)
    • (2002) Journal of the Neurological Sciences , vol.199 , Issue.1-2 , pp. 17-24
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 68
    • 36248932105 scopus 로고    scopus 로고
    • Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke
    • DOI 10.1634/stemcells.2007-0169
    • Cui X, Chen J, Zacharek A, Li Y, Roberts C, Kapke A, et al. Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke. Stem Cells 2007, 25: 2777-2785. (Pubitemid 350127862)
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2777-2785
    • Cui, X.1    Chen, J.2    Zacharek, A.3    Li, Y.4    Roberts, C.5    Kapke, A.6    Savant-Bhonsale, S.7    Chopp, M.8
  • 69
    • 51249108621 scopus 로고    scopus 로고
    • Treatment of stroke with (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate and bone marrow stromal cells upregulates angiopoietin-1/Tie2 and enhances neovascularization
    • Cui X, Chen J, Zacharek A, Roberts C, Savant-Bhonsale S, Chopp M. Treatment of stroke with (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) amino] diazen-1-ium-1, 2-diolate and bone marrow stromal cells upregulates angiopoietin-1/Tie2 and enhances neovascularization. Neuroscience 2008, 156: 155-164.
    • (2008) Neuroscience , vol.156 , pp. 155-164
    • Cui, X.1    Chen, J.2    Zacharek, A.3    Roberts, C.4    Savant-Bhonsale, S.5    Chopp, M.6
  • 70
    • 38749116949 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats
    • Shyu WC, Lin SZ, Yen PS, Su CY, Chen DC, Wang HJ, et al. Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats. J Pharmacol Exp Ther 2008, 324: 834-849.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 834-849
    • Shyu, W.C.1    Lin, S.Z.2    Yen, P.S.3    Su, C.Y.4    Chen, D.C.5    Wang, H.J.6
  • 71
    • 84862825091 scopus 로고    scopus 로고
    • Sodium Ferulate combined with bone marrow stromal cell treatment ameliorating rat brain ischemic injury after stroke
    • Zhao Y, Guan Y, Xu Y, Li Y, Wu W. Sodium Ferulate combined with bone marrow stromal cell treatment ameliorating rat brain ischemic injury after stroke. Brain Res 2012, 1450: 157-165.
    • (2012) Brain Res , vol.1450 , pp. 157-165
    • Zhao, Y.1    Guan, Y.2    Xu, Y.3    Li, Y.4    Wu, W.5
  • 72
    • 77952995365 scopus 로고    scopus 로고
    • Noninvasive transplantation of bone marrow stromal cells for ischemic stroke: Preliminary study with a thermoreversible gelation polymer hydrogel
    • discussion 1147
    • Osanai T, Kuroda S, Yasuda H, Chiba Y, Maruichi K, Hokari M, et al. Noninvasive transplantation of bone marrow stromal cells for ischemic stroke: preliminary study with a thermoreversible gelation polymer hydrogel. Neurosurgery 2010, 66: 1140-1147; discussion 1147.
    • (2010) Neurosurgery , vol.66 , pp. 1140-1147
    • Osanai, T.1    Kuroda, S.2    Yasuda, H.3    Chiba, Y.4    Maruichi, K.5    Hokari, M.6
  • 73
    • 84861318561 scopus 로고    scopus 로고
    • Therapeutic effects of a combinatorial treatment of simvastatin and bone marrow stromal cells on experimental embolic stroke
    • Pirzad Jahromi G, Seidi S, Sadr SS, Shabanzadeh AP, Keshavarz M, Kaka GR, et al. Therapeutic effects of a combinatorial treatment of simvastatin and bone marrow stromal cells on experimental embolic stroke. Basic Clin Pharmacol Toxicol 2012, 110: 487-493.
    • (2012) Basic Clin Pharmacol Toxicol , vol.110 , pp. 487-493
    • Pirzad Jahromi, G.1    Seidi, S.2    Sadr, S.S.3    Shabanzadeh, A.P.4    Keshavarz, M.5    Kaka, G.R.6
  • 74
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • DOI 10.1002/ana.20501
    • Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 2005, 57: 874-882. (Pubitemid 40798626)
    • (2005) Annals of Neurology , vol.57 , Issue.6 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 75
    • 77956638921 scopus 로고    scopus 로고
    • A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke
    • Lee JS, Hong JM, Moon GJ, Lee PH, Ahn YH, Bang OY. A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Stem Cells 2010, 28: 1099-1106.
    • (2010) Stem Cells , vol.28 , pp. 1099-1106
    • Lee, J.S.1    Hong, J.M.2    Moon, G.J.3    Lee, P.H.4    Ahn, Y.H.5    Bang, O.Y.6
  • 78
    • 84864284648 scopus 로고    scopus 로고
    • Intra-arterial bone marrow mononuclear cells in ischemic stroke: A pilot clinical trial
    • Moniche F, Gonzalez A, Gonzalez-Marcos JR, Carmona M, Pinero P, Espigado I, et al. Intra-arterial bone marrow mononuclear cells in ischemic stroke: a pilot clinical trial. Stroke 2012, 43: 2242-2244.
    • (2012) Stroke , vol.43 , pp. 2242-2244
    • Moniche, F.1    Gonzalez, A.2    Gonzalez-Marcos, J.R.3    Carmona, M.4    Pinero, P.5    Espigado, I.6
  • 79
    • 84930486490 scopus 로고    scopus 로고
    • Intra-arterial infusion of autologous bone marrow mononuclear cells in patients with moderate to severe middle cerebral artery acute ischemic stroke
    • Friedrich MA, Martins MP, Araujo MD, Klamt C, Vedolin L, Garicochea B, et al. Intra-arterial infusion of autologous bone marrow mononuclear cells in patients with moderate to severe middle cerebral artery acute ischemic stroke. Cell Transplant 2012, 21 Suppl 1: S13-21.
    • (2012) Cell Transplant , vol.21 , Issue.SUPPL. 1
    • Friedrich, M.A.1    Martins, M.P.2    Araujo, M.D.3    Klamt, C.4    Vedolin, L.5    Garicochea, B.6


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