Comparison of Bone Marrow Stromal Cells Derived from Stroke and Normal Rats for Stroke Treatment

Stroke

Volumn 41, Issue 3, 2010, Pages 524-530

  Zacharek, Alex ^a   Shehadah, Amjad ^a   Chen, Jieli ^a   Cui, Xu ^a   Roberts, Cynthia ^a   Lu, Mei ^b,c   Chopp, Michael ^a,b  

^a Departments of Neurology   (United States)

^b HENRY FORD HEALTH SCIENCES CENTER   (United States)

^c OAKLAND UNIVERSITY   (United States)

Author keywords

Ang1; Angiogenesis; Axonal regeneration; Bone marrow stromal cell; Cerebral infarct; Tie2

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; BASIC FIBROBLAST GROWTH FACTOR; NEUROTROPHIC FACTOR; SMALL INTERFERING RNA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CELL MIGRATION; CELL THERAPY; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; GLIA CELL; HISTOPATHOLOGY; MALE; MIDDLE CEREBRAL ARTERY; NERVE FIBER REGENERATION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; STROMA CELL;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELLS, CULTURED; MALE; RATS; RATS, WISTAR; STROKE; STROMAL CELLS; TREATMENT OUTCOME;

EID: 77649092027     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.109.568881     Document Type: Article

References (22)

1. Takahashi K, Yasuhara T, Shingo T, Muraoka K, Kameda M, Takeuchi A, Yano A, Kurozumi K, Agari T, Miyoshi Y, Kinugasa K, Date I. Embryonic neural stem cells transplanted in middle cerebral artery occlusion model of rats demonstrated potent therapeutic effects, compared to adult neural stem cells. Brain Res. 2008;1234:172-182.
2. Mochizuki N, Takagi N, Kurokawa K, Onozato C, Moriyama Y, Tanonaka K, Takeo S. Injection of neural progenitor cells improved learning and memory dysfunction after cerebral ischemia. Exp Neurol. 2008;211:194-202.
3. Kozlowska H, Jablonka J, Janowski M, Jurga M, Kossut M, Domanska-Janik K. Transplantation of a novel human cord blood-derived neural-like stem cell line in a rat model of cortical infarct. Stem Cells Dev. 2007;16:481-488.
4. Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol. 2002;174:11-20.
5. Taguchi A, Soma T, Tanaka H, Kanda T, Nishimura H, Yoshikawa H, Tsukamoto Y, Iso H, Fujimori Y, Stern DM, Naritomi H, Matsuyama T. Administration of cd34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest. 2004;114:330-338.
6. Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;57:874-882.
7. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke. 2001;32:1005-1011. (Pubitemid 32285175)
8. Zacharek A, Chen J, Cui X, Li A, Li Y, Roberts C, Feng Y, Gao Q, Chopp M. Angiopoietin1/Tie2 and VEGF/flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke. J Cereb Blood Flow Metab. 2007;27:1684-1691.
9. Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD. Requisite role of Angiopoietin-1, a ligand for the Tie2 receptor, during embryonic angiogenesis. Cell. 1996;87:1171-1180. (Pubitemid 27010101)
10. Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989;20: 84-91.
11. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR. A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab. 1990;10:290-293.
12. Zhang J, Li Y, Lu M, Cui Y, Chen J, Noffsinger L, Elias SB, Chopp M. Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice. J Neurosci Res. 2006;84:587-595.
13. Wu Z, Hofman FM, Zlokovic BV. A simple method for isolation and characterization of mouse brain microvascular endothelial cells. J Neurosci Methods. 2003;130:53-63.
14. Legrand C, Bour JM, Jacob C, Capiaumont J, Martial A, Marc A, Wudtke M, Kretzmer G, Demangel C, Duval D, et al. Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]. J Biotechnol. 1992;25:231-243.
15. Chen J, Cui X, Zacharek A, Roberts C, Chopp M. eNOS mediates to90317 treatment-induced angiogenesis and functional outcome after stroke in mice. Stroke. 2009;40:2532-2538.
16. Chen J, Zhang ZG, Li Y, Wang L, Xu YX, Gautam SC, Lu M, Zhu Z, Chopp M. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res. 2003;92:692-699. (Pubitemid 36417705)
17. Patan S. Vasculogenesis and angiogenesis. Cancer Treat Res. 2004; 117:3-32.
18. Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, Wang JA, Wei L. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg. 2008;135:799-808.
19. Rosova I, Dao M, Capoccia B, Link D, Nolta JA. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells. 2008;26:2173-2182.
20. Uemura R, Xu M, Ahmad N, Ashraf M. Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res. 2006;98:1414-1421.
21. Sun L, Cui M, Wang Z, Feng X, Mao J, Chen P, Kangtao M, Chen F, Zhou C. Mesenchymal stem cells modified with Angiopoietin-1 improve remodeling in a rat model of acute myocardial infarction. Biochem Biophys Res Commun. 2007;357:779-784.
22. Gluzman Z, Koren B, Preis M, Cohen T, Tsaba A, Cosset FL, Shofti R, Lewis BS, Virmani R, Flugelman MY. Endothelial cells are activated by Angiopoeitin-1 gene transfer and produce coordinated sprouting in vitro and arteriogenesis in vivo. Biochem Biophys Res Commun. 2007;359: 263-268.