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Volumn 18, Issue 3, 2014, Pages 371-379

Dosage individualization of warfarin using artificial neural networks

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANTIFUNGAL AGENT; CARBAMAZEPINE; CYTOCHROME P450 2C9; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MACROLIDE; PHENYTOIN; PROTEIN; PROTEIN VKORC1; PYRROLE; RIFAMPICIN; SULFONAMIDE; UNCLASSIFIED DRUG; WARFARIN;

EID: 84902382974     PISSN: 11771062     EISSN: 11792000     Source Type: Journal    
DOI: 10.1007/s40291-014-0090-7     Document Type: Article
Times cited : (19)

References (50)
  • 1
    • 84866493944 scopus 로고    scopus 로고
    • A new warfarin dosing algorithm including VKORC1 3730 G>A polymorphism: Comparison with results obtained by other published algorithms
    • Cini M, Legnani C, Cosmi B, Guazzaloca G, Valdre L, Frascaro M, et al. A new warfarin dosing algorithm including VKORC1 3730 G>A polymorphism: comparison with results obtained by other published algorithms. Eur J Clin Pharmacol. 2012;68(8):1167-74.
    • (2012) Eur J Clin Pharmacol , vol.68 , Issue.8 , pp. 1167-1174
    • Cini, M.1    Legnani, C.2    Cosmi, B.3    Guazzaloca, G.4    Valdre, L.5    Frascaro, M.6
  • 2
    • 77953624552 scopus 로고    scopus 로고
    • Role of warfarin pharmacogenetic testing in clinical practice
    • Tan GM, Wu E, Lam YY, Yan BP. Role of warfarin pharmacogenetic testing in clinical practice. Pharmacogenomics. 2010;11(3):439-48.
    • (2010) Pharmacogenomics , vol.11 , Issue.3 , pp. 439-448
    • Tan, G.M.1    Wu, E.2    Lam, Y.Y.3    Yan, B.P.4
  • 4
    • 81855169543 scopus 로고    scopus 로고
    • Emergency hospitalizations for adverse drug events in older Americans
    • Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med. 2011;365(21):2002-12.
    • (2011) N Engl J Med , vol.365 , Issue.21 , pp. 2002-2012
    • Budnitz, D.S.1    Lovegrove, M.C.2    Shehab, N.3    Richards, C.L.4
  • 5
    • 84855663263 scopus 로고    scopus 로고
    • Anticoagulant management in the cardiovascular setting
    • Verheugt FW. Anticoagulant management in the cardiovascular setting. Fundam Clin Pharmacol. 2012;26(1):11-5.
    • (2012) Fundam Clin Pharmacol , vol.26 , Issue.1 , pp. 11-15
    • Verheugt, F.W.1
  • 6
    • 23044440450 scopus 로고    scopus 로고
    • The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: Proposal for a new dosing regimen
    • DOI 10.1182/blood-2005-03-1108
    • Sconce EA, Khan TI, Wynne HA, Avery P, Monkhouse L, King BP, et al. The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen. Blood. 2005;106(7):2329-33. (Pubitemid 41510803)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2329-2333
    • Sconce, E.A.1    Khan, T.I.2    Wynne, H.A.3    Avery, P.4    Monkhouse, L.5    King, B.P.6    Wood, P.7    Kesteven, P.8    Daly, A.K.9    Kamali, F.10
  • 9
    • 60849097257 scopus 로고    scopus 로고
    • Estimation of the warfarin dose with clinical and pharmacogenetic data
    • International Warfarin Pharmacogenetics C
    • International Warfarin Pharmacogenetics C, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE, et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med. 2009;360(8):753-64.
    • (2009) N Engl J Med , vol.360 , Issue.8 , pp. 753-764
    • Klein, T.E.1    Altman, R.B.2    Eriksson, N.3    Gage, B.F.4    Kimmel, S.E.5
  • 10
    • 41149090966 scopus 로고    scopus 로고
    • Principles of artificial neural networks
    • ebrary Inc. 2nd ed. Singapore; Hackensack, N.J.: World Scientific
    • Graupe D, ebrary Inc. Principles of artificial neural networks. Advanced series on circuits and systems vol 6. 2nd ed. Singapore; Hackensack, N.J.: World Scientific,; 2007. p. xv, 303 p.
    • (2007) Advanced Series on Circuits and Systems , vol.6
    • Graupe, D.1
  • 11
    • 0034213103 scopus 로고    scopus 로고
    • Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research
    • DOI 10.1016/S0731-7085(99)00272-1, PII S0731708599002721
    • Agatonovic-Kustrin S, Beresford R. Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research. J Pharma Biomed Anal. 2000;22(5):717-27. (Pubitemid 30193303)
    • (2000) Journal of Pharmaceutical and Biomedical Analysis , vol.22 , Issue.5 , pp. 717-727
    • Agatonovic-Kustrin, S.1    Beresford, R.2
  • 13
    • 0038355073 scopus 로고    scopus 로고
    • Pharmacodynamic population analysis in chronic renal failure using artificial neural networks - A comparative study
    • DOI 10.1016/S0893-6080(03)00084-4
    • Gaweda AE, Jacobs AA, Brier ME, Zurada JM. Pharmacodynamic population analysis in chronic renal failure using artificial neural networks-a comparative study. Neural Netw. 2003;16(5-6):841-5. (Pubitemid 36794360)
    • (2003) Neural Networks , vol.16 , Issue.5-6 , pp. 841-845
    • Gaweda, A.E.1    Jacobs, A.A.2    Brier, M.E.3    Zurada, J.M.4
  • 17
    • 77951758756 scopus 로고    scopus 로고
    • Validation and comparison of pharmacogenetics-based warfarin dosing algorithms for application of pharmacogenetic testing
    • Roper N, Storer B, Bona R, Fang M. Validation and comparison of pharmacogenetics-based warfarin dosing algorithms for application of pharmacogenetic testing. J Mol Diagn JMD. 2010;12(3):283-91.
    • (2010) J Mol Diagn JMD , vol.12 , Issue.3 , pp. 283-291
    • Roper, N.1    Storer, B.2    Bona, R.3    Fang, M.4
  • 19
    • 0027465617 scopus 로고
    • A genetic algorithm to improve a neural network to predict a patient's response to warfarin
    • Narayanan MN, Lucas SB. A genetic algorithm to improve a neural network to predict a patient's response to warfarin. Methods Inf Med. 1993;32(1):55-8. (Pubitemid 23117617)
    • (1993) Methods of Information in Medicine , vol.32 , Issue.1 , pp. 55-58
    • Naryanan, M.N.1    Lucas, S.B.2
  • 20
    • 84865552342 scopus 로고    scopus 로고
    • Predicting warfarin dosage from clinical data: A supervised learning approach
    • Hu YH, Wu F, Lo CL, Tai CT. Predicting warfarin dosage from clinical data: a supervised learning approach. Artif Intell Med. 2012;56(1):27-34.
    • (2012) Artif Intell Med , vol.56 , Issue.1 , pp. 27-34
    • Hu, Y.H.1    Wu, F.2    Lo, C.L.3    Tai, C.T.4
  • 21
    • 47949086046 scopus 로고    scopus 로고
    • Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
    • Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, Ridker PM, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther. 2008;84(3):326-31.
    • (2008) Clin Pharmacol Ther , vol.84 , Issue.3 , pp. 326-331
    • Gage, B.F.1    Eby, C.2    Johnson, J.A.3    Deych, E.4    Rieder, M.J.5    Ridker, P.M.6
  • 23
    • 0035128503 scopus 로고    scopus 로고
    • Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
    • Hirsh J, Dalen J, Anderson DR, Poller L, Bussey H, Ansell J, et al. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest. 2001;119(1 Suppl):8S-21S. (Pubitemid 32154192)
    • (2001) Chest , vol.119 , Issue.1 SUPPL.
    • Hirsh, J.1    Dalen, J.E.2    Anderson, D.R.3    Poller, L.4    Bussey, H.5    Ansell, J.6    Deykin, D.7
  • 26
    • 0026468933 scopus 로고
    • Aging and warfarin therapy
    • Mungall D, White R. Aging and warfarin therapy. Ann Intern Med. 1992;117(10):878-9.
    • (1992) Ann Intern Med , vol.117 , Issue.10 , pp. 878-879
    • Mungall, D.1    White, R.2
  • 28
    • 84856072430 scopus 로고    scopus 로고
    • Vitamin K antagonists in children with heart disease: Height and VKORC1 genotype are the main determinants of the warfarin dose requirement
    • Moreau C, Bajolle F, Siguret V, Lasne D, Golmard JL, Elie C, et al. Vitamin K antagonists in children with heart disease: height and VKORC1 genotype are the main determinants of the warfarin dose requirement. Blood. 2012;119(3):861-7.
    • (2012) Blood , vol.119 , Issue.3 , pp. 861-867
    • Moreau, C.1    Bajolle, F.2    Siguret, V.3    Lasne, D.4    Golmard, J.L.5    Elie, C.6
  • 30
    • 51749118719 scopus 로고    scopus 로고
    • Effect of race/ethnicity on the efficacy of warfarin: Potential implications for prevention of stroke in patients with atrial fibrillation
    • Shen AY, Chen W, Yao JF, Brar SS, Wang X, Go AS. Effect of race/ethnicity on the efficacy of warfarin: potential implications for prevention of stroke in patients with atrial fibrillation. CNS Drugs. 2008;22(10):815-25.
    • (2008) CNS Drugs , vol.22 , Issue.10 , pp. 815-825
    • Shen, A.Y.1    Chen, W.2    Yao, J.F.3    Brar, S.S.4    Wang, X.5    Go, A.S.6
  • 31
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • DOI 10.1016/S0163-7258(96)00140-4, PII S0163725896001404
    • Kaminsky LS, Zhang ZY. Human P450 metabolism of warfarin. Pharmacol Ther. 1997;73(1):67-74. (Pubitemid 26425815)
    • (1997) Pharmacology and Therapeutics , vol.73 , Issue.1 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.-Y.2
  • 32
    • 40949119786 scopus 로고    scopus 로고
    • VKORC1: A warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors
    • Wallin R, Wajih N, Hutson SM. VKORC1: a warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors. Vitam Horm. 2008;78:227-46.
    • (2008) Vitam Horm , vol.78 , pp. 227-246
    • Wallin, R.1    Wajih, N.2    Hutson, S.M.3
  • 33
    • 54249118120 scopus 로고    scopus 로고
    • Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: Interactions and the risk of hospitalization for gastrointestinal bleeding
    • Schelleman H, Bilker WB, Brensinger CM, Han X, Kimmel SE, Hennessy S. Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding. Clin Pharmacol Ther. 2008;84(5):581-8.
    • (2008) Clin Pharmacol Ther , vol.84 , Issue.5 , pp. 581-588
    • Schelleman, H.1    Bilker, W.B.2    Brensinger, C.M.3    Han, X.4    Kimmel, S.E.5    Hennessy, S.6
  • 34
    • 84862937732 scopus 로고    scopus 로고
    • Concurrent use of warfarin and antibiotics and the risk of bleeding in older adults
    • Baillargeon J, Holmes HM, Lin YL, Raji MA, Sharma G, Kuo YF. Concurrent use of warfarin and antibiotics and the risk of bleeding in older adults. Am J Med. 2012;125(2):183-9.
    • (2012) Am J Med , vol.125 , Issue.2 , pp. 183-189
    • Baillargeon, J.1    Holmes, H.M.2    Lin, Y.L.3    Raji, M.A.4    Sharma, G.5    Kuo, Y.F.6
  • 35
    • 0030824584 scopus 로고    scopus 로고
    • A review of enzyme induction of warfarin metabolism with recommendations for patient management
    • Cropp JS, Bussey HI. A review of enzyme induction of warfarin metabolism with recommendations for patient management. Pharmacotherapy. 1997;17(5):917-28. (Pubitemid 27415096)
    • (1997) Pharmacotherapy , vol.17 , Issue.5 I , pp. 917-928
    • Cropp, J.S.1    Bussey, H.I.2
  • 39
    • 82755166898 scopus 로고    scopus 로고
    • From pharmacogenomic knowledge acquisition to clinical applications: The PharmGKB as a clinical pharmacogenomic biomarker resource
    • McDonagh EM, Whirl-Carrillo M, Garten Y, Altman RB, Klein TE. From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource. Biomarkers Med. 2011;5(6):795-806.
    • (2011) Biomarkers Med , vol.5 , Issue.6 , pp. 795-806
    • McDonagh, E.M.1    Whirl-Carrillo, M.2    Garten, Y.3    Altman, R.B.4    Klein, T.E.5
  • 41
    • 27744516938 scopus 로고    scopus 로고
    • Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing
    • DOI 10.1182/blood-2005-04-1711
    • Chen LY, Eriksson N, Gwilliam R, Bentley D, Deloukas P, Wadelius M. Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing. Blood. 2005;106(10):3673-4. (Pubitemid 41609210)
    • (2005) Blood , vol.106 , Issue.10 , pp. 3673-3674
    • Chen, L.Y.1    Eriksson, N.2    Gwilliam, R.3    Bentley, D.4    Deloukas, P.5    Wadelius, M.6
  • 42
    • 1642335299 scopus 로고    scopus 로고
    • Association of pharmacokinetic (CY72C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity
    • DOI 10.1182/blood-2003-09-3043
    • Shikata E, Ieiri I, Ishiguro S, Aono H, Inoue K, Koide T, et al. Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gammaglutamyl carboxylase) gene variants with warfarin sensitivity. Blood. 2004;103(7):2630-5. (Pubitemid 38393017)
    • (2004) Blood , vol.103 , Issue.7 , pp. 2630-2635
    • Shikata, E.1    Ieiri, I.2    Ishiguro, S.3    Aono, H.4    Inoue, K.5    Koide, T.6    Ohgi, S.7    Otsubo, K.8
  • 43
    • 38349098717 scopus 로고    scopus 로고
    • Apolipoprotein E genotype and warfarin dosing among Caucasians and African Americans
    • Kimmel SE, Christie J, Kealey C, Chen Z, Price M, Thorn CF, et al. Apolipoprotein E genotype and warfarin dosing among Caucasians and African Americans. Pharmacogenomics J. 2008;8(1):53-60.
    • (2008) Pharmacogenomics J , vol.8 , Issue.1 , pp. 53-60
    • Kimmel, S.E.1    Christie, J.2    Kealey, C.3    Chen, Z.4    Price, M.5    Thorn, C.F.6
  • 44
    • 44949234553 scopus 로고    scopus 로고
    • Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans
    • DOI 10.2217/14622416.9.5.511
    • Limdi NA, Arnett DK, Goldstein JA, Beasley TM, McGwin G, Adler BK, et al. Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans. Pharmacogenomics. 2008;9(5):511-26. (Pubitemid 351803913)
    • (2008) Pharmacogenomics , vol.9 , Issue.5 , pp. 511-526
    • Limdi, N.A.1    Arnett, D.K.2    Goldstein, J.A.3    Beasley, T.M.4    McGwin, G.5    Adler, B.K.6    Acton, R.T.7
  • 45
    • 77952570889 scopus 로고    scopus 로고
    • Warfarin pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across 3 racial groups
    • Limdi NA, Wadelius M, Cavallari L, Eriksson N, Crawford DC, Lee MTM, et al. Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood. 2010;115(18):3827-34.
    • (2010) Blood , vol.115 , Issue.18 , pp. 3827-3834
    • Limdi, N.A.1    Wadelius, M.2    Cavallari, L.3    Eriksson, N.4    Crawford, D.C.5    Lee, M.T.M.6
  • 46
    • 84883135237 scopus 로고    scopus 로고
    • Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study
    • Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, et al. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet. 2013;382(9894):790-6.
    • (2013) Lancet , vol.382 , Issue.9894 , pp. 790-796
    • Perera, M.A.1    Cavallari, L.H.2    Limdi, N.A.3    Gamazon, E.R.4    Konkashbaev, A.5    Daneshjou, R.6
  • 47
    • 0017726993 scopus 로고
    • Predicting patients' warfarin requirements
    • Routledge PA, Davies DM, Bell SM, Cavanagh JS, Rawlins MD. Predicting patients' warfarin requirements. Lancet. 1977;2(8043):854-5. (Pubitemid 8199533)
    • (1977) Lancet , vol.2 , Issue.8043 , pp. 854-855
    • Routledge, P.A.1    Davies, D.M.2    Bell, S.M.3
  • 48
    • 0021970460 scopus 로고
    • Multicenter evaluation of six methods for predicting warfarin maintenance-dose requirements from initial response
    • Sawyer WT, Poe TE, Canaday BR, Weiner JS, Williams DM, Webb CE, et al. Multicenter evaluation of six methods for predicting warfarin maintenance-dose requirements from initial response. Clin Pharm. 1985;4(4):440-6. (Pubitemid 15234458)
    • (1985) Clinical Pharmacy , vol.4 , Issue.4 , pp. 440-446
    • Sawyer, W.T.1    Poe, T.E.2    Canaday, B.R.3
  • 49
    • 67949086757 scopus 로고    scopus 로고
    • Predicting warfarin maintenance dose in patients with venous thromboembolism based on the response to a standardized warfarin initiation nomogram
    • Lazo-Langner A, Monkman K, Kovacs MJ. Predicting warfarin maintenance dose in patients with venous thromboembolism based on the response to a standardized warfarin initiation nomogram. J Thromb Haemost. 2009;7(8):1276-83.
    • (2009) J Thromb Haemost , vol.7 , Issue.8 , pp. 1276-1283
    • Lazo-Langner, A.1    Monkman, K.2    Kovacs, M.J.3
  • 50
    • 73049115063 scopus 로고    scopus 로고
    • Prediction of the warfarin maintenance dose after completion of the 10 mg initiation nomogram: Do we really need genotyping?
    • Le Gal G, Carrier M, Tierney S, Majeed H, Rodger M, Wells PS. Prediction of the warfarin maintenance dose after completion of the 10 mg initiation nomogram: do we really need genotyping? J Thromb Haemost. 2010;8(1):90-4.
    • (2010) J Thromb Haemost , vol.8 , Issue.1 , pp. 90-94
    • Le Gal, G.1    Carrier, M.2    Tierney, S.3    Majeed, H.4    Rodger, M.5    Wells, P.S.6


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