Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of α2β1 integrin and E-cadherin function

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Bassagañas, Sònia ^a   Carvalho, Sandra ^b   Dias, Ana M ^b   Pérez Garay, Marta ^a   Ortiz, M Rosa ^c   Figueras, Joan ^d   Reis, Celso A ^b,e   Pinho, Salomé S ^b   Peracaula, Rosa ^a  

^a UNIVERSITY OF GIRONA   (Spain)

^b UNIVERSITY OF PORTO   (Portugal)

^c HOSPITAL JOSEP TRUETA   (Spain)

^d Dr Josep Trueta University Hospital   (Spain)

^e University of Porto   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2,6 SIALIC ACID; ALPHA2 INTEGRIN; COLLAGEN TYPE 1; FOCAL ADHESION KINASE; GLYCAN; GLYCOSYLTRANSFERASE; SIALIC ACID DERIVATIVE; SIALYL LEWIS X ANTIGEN; ST3GAL III GLYCOSYLTRANSFERASE; UNCLASSIFIED DRUG; UVOMORULIN; VERY LATE ACTIVATION ANTIGEN 2; CADHERIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CELL ADHESION; CELL AGGREGATION; CELL CONTACT; CELL MIGRATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR DYNAMICS; PANCREATIC CANCER CELL LINE; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIALYLATION; TUMOR INVASION; GLYCOSYLATION; METABOLISM; PANCREAS TUMOR; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

CADHERINS; CELL ADHESION; CELL AGGREGATION; COLLAGEN TYPE I; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLYCOSYLATION; HUMANS; INTEGRIN ALPHA2BETA1; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84902337828     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098595     Document Type: Article

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