Liquid chromatography-high resolution/high accuracy (tandem) mass spectrometrybased identification of in vivo generated metabolites of the selective androgen receptor modulator ACP-105 for doping control purposes

European Journal of Mass Spectrometry

Volumn 20, Issue 1, 2014, Pages 73-83

  Thevis, Mario ^a,c   Thomas, Andreas As ^a   Piper, Thomas S ^a   Krug, Oliver R ^a,c   Delahaut, Philippe Ppe ^b   Schänzer, Wilhelm Lm ^a  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b CER Groupe   (Belgium)

^c European Monitoring Center for Emerging Doping Agents   (Germany)

Author keywords

Anabolic agent; Doping; Mass spectrometry; SARMs; Sport

Indexed keywords

BIOMOLECULES; CONTROLLED DRUG DELIVERY; DOPING (ADDITIVES); DRUG PRODUCTS; ENZYMATIC HYDROLYSIS; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; MODULATORS; SPORTS; TESTING;

ANABOLIC AGENTS; CHEMICAL DERIVATIZATION; COLLISIONAL ACTIVATION; DISSOCIATION PATHWAYS; LIQUID-LIQUID EXTRACTION; ORAL ADMINISTRATION; SARMS; WORLD ANTI-DOPING AGENCY;

LIQUID CHROMATOGRAPHY;

2-CHLORO-4-(3-HYDROXY-3-METHYL-8-AZABICYCLO(3.2.1)OCT-8-YL)-3-METHYLBENZONITRILE; 2 CHLORO 4 (3 HYDROXY 3 METHYL 8 AZABICYCLO(3.2.1)OCT 8 YL) 3 METHYLBENZONITRILE; ANABOLIC AGENT; ANDROGEN RECEPTOR; AZABICYCLO DERIVATIVE;

ANIMAL; ARTICLE; DOPING; DRUG EFFECT; FEMALE; HUMAN; HYDROLYSIS; HYDROXYLATION; LIQUID CHROMATOGRAPHY; MALE; METHODOLOGY; RAT; SPRAGUE DAWLEY RAT; SUBSTANCE ABUSE; TANDEM MASS SPECTROMETRY; URINE;

ANABOLIC AGENTS; ANIMALS; AZABICYCLO COMPOUNDS; CHROMATOGRAPHY, LIQUID; DOPING IN SPORTS; FEMALE; HUMANS; HYDROLYSIS; HYDROXYLATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 84902332756     PISSN: None     EISSN: 17516838     Source Type: Journal    
DOI: 10.1255/ejms.1236     Document Type: Article

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