A treatment with a protease inhibitor recombinant from the cattle tick (Rhipicephalus Boophilus microplus) ameliorates emphysema in mice

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Lourenço, Juliana D ^a   Neves, Luana P ^c   Olivo, Clarice R ^a   Duran, Adriana ^c   Almeida, Francine M ^a   Arantes, Petra M M ^a   Prado, Carla M ^b   Leick, Edna Aparecida ^a   Tanaka, Aparecida S ^b   Martins, Mílton A ^a   Sasaki, Sergio D ^c   Lopes, Fernanda D T Q S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSIDADE FEDERAL DO ABC   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBER; MACROPHAGE ELASTASE; RECOMBINANT PROTEIN BMTI A; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; COLLAGEN; GALECTIN 3; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN;

AIRWAY RESISTANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING MECHANICS; CELL COUNT; CONTROLLED STUDY; DRUG TARGETING; ELASTIC FIBER; EMPHYSEMA; FEMALE; LUNG COMPLIANCE; LUNG LAVAGE; MACROPHAGE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ANIMAL; BOVINAE; C57BL MOUSE; DRUG EFFECTS; ELASTICITY; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOPHYSIOLOGY; PULMONARY EMPHYSEMA; RHIPICEPHALUS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CATTLE; COLLAGEN; ELASTICITY; GALECTIN 3; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASE 12; MICE, INBRED C57BL; PROTEASE INHIBITORS; PULMONARY EMPHYSEMA; RECOMBINANT PROTEINS; RESPIRATORY MECHANICS; RHIPICEPHALUS;

EID: 84902308401     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098216     Document Type: Article

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