Peripheral nervous system origin of phantom limb pain

Pain

Volumn 155, Issue 7, 2014, Pages 1384-1391

  Vaso, Apostol ^a   Adahan, Haim Moshe ^b   Gjika, Artan ^a   Zahaj, Skerdi ^a   Zhurda, Tefik ^a   Vyshka, Gentian ^c   Devor, Marshall ^d  

^a UNIVERSITY HOSPITAL CENTER MOTHER TERESA   (Albania)

^b SHEBA MEDICAL CENTER   (Israel)

^c University of Medicine   (Albania)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

DRG; Ectopic firing; Electrogenesis; Intraforaminal; Neuropathic pain; Phantom limb pain

Indexed keywords

LIDOCAINE; LOCAL ANESTHETIC AGENT;

ADULT; AGED; AGNOSIA; ARTICLE; CENTRAL NERVOUS SYSTEM; CLINICAL ARTICLE; DISABLED PERSON; ECTOPIC TISSUE; FEMALE; HUMAN; MALE; NERVE BLOCK; NEUROPATHIC PAIN; PERIPHERAL NERVOUS SYSTEM; PHANTOM PAIN; PRIORITY JOURNAL; SENSORY NERVE; SPINAL ANESTHESIA; SPINAL GANGLION; INTRASPINAL DRUG ADMINISTRATION; MIDDLE AGED; NEURALGIA; PATHOPHYSIOLOGY; PERIPHERAL NERVE; PHANTOM LIMB; PHYSIOLOGY; SENSORY NERVE CELL; YOUNG ADULT;

ADULT; AGED; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; FEMALE; GANGLIA, SPINAL; HUMANS; INJECTIONS, SPINAL; LIDOCAINE; MALE; MIDDLE AGED; NERVE BLOCK; NEURALGIA; NEURONS, AFFERENT; PERIPHERAL NERVES; PHANTOM LIMB; YOUNG ADULT;

EID: 84902299742     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2014.04.018     Document Type: Article

References (66)

1. V.C. Anderson-Barnes, C. McAuliffe, K.M. Swanberg, and J.W. Tsao Phantom limb pain - a phenomenon of proprioceptive memory? Med Hypotheses 73 2009 555 558
2. R.C. Babbedge, A.J. Soper, C.T. Gentry, V.C. Hood, E.A. Campbell, and L. Urban In vitro characterization of a peripheral afferent pathway of the rat after chronic sciatic nerve section J Neurophysiol 76 1996 3169 3177
3. A.M. Binshtok, B.P. Bean, and C.J. Woolf Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers Nature 449 2007 607 610
4. N. Birbaumer, W. Lutzenberger, P. Montoya, W. Larbig, K. Unertl, S. Töpfner, W. Grodd, E. Taub, and H. Flor Effects of regional anesthesia on phantom limb pain are mirrored in changes in cortical reorganization J Neurosci 17 1997 5503 5508
5. J.A. Black, L. Nikolajsen, K. Kroner, T.S. Jensen, and S.G. Waxman Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas Ann Neurol 64 2008 644 653
6. G. Byrod, B. Rydevik, B.R. Johansson, and K. Olmarker Transport of epidurally applied horseradish peroxidase to the endoneurial space of dorsal root ganglia: a light and electron microscopic study J Periph Nerv Syst 5 2000 218 226
7. R.L. Clark, F.L. Bowling, F. Jepson, and S. Rajbhandari Phantom limb pain after amputation in diabetic patients does not differ from that after amputation in nondiabetic patients PAIN® 154 2013 729 732
8. L. Colloca, L. Lopiano, M. Lanotte, and F. Benedetti Overt versus covert treatment for pain, anxiety, and Parkinson's disease Lancet Neurol 3 2004 679 684
9. B. Cronholm Phantom limb in amputees: study of changes in integration of centripetal impulses with special reference to referred sensations Acta Psychiatr Neurol Scand 72 1951 1 85
10. A. Dalal, M. Tata, G. Allègre, F. Gekiere, N. Bons, and D. Albe-Fessard Spontaneous activity of rat dorsal horn cells in spinal segments of sciatic projection following transection of sciatic nerve or of corresponding dorsal roots Neuroscience 94 1999 217 228
11. deJong RH. Local anaesthetics. St Louis: Mosby; 1994.
12. M. Devor Central changes after nerve injury W. Willis, R. Schmidt, Encyclopedia of pain 2007 Springer Verlag Berlin
13. M. Devor Centralization, central sensitization and neuropathic pain. Focus on "sciatic chronic constriction injury produces cell-type-specific changes in the electrophysiological properties of rat substantia gelatinosa neurons" J Neurophysiol 96 2006 522 523
14. M. Devor Neuropathic pain: pathophysiological response of nerves to injury S.L. McMahon, M. Koltzenburg, I. Tracey, D.T. Turk, Wall and Melzack's textbook of pain 6th ed. 2013 Churchill Livingstone London 861 888
15. M. Devor, R. Govrin-Lippmann, and P. Raber Corticosteroids suppress ectopic neuronal discharge originating in experimental neuromas PAIN® 22 1985 127 137
16. M. Devor, and P.D. Wall Reorganization of the spinal cord sensory map after peripheral nerve injury Nature 276 1978 76
17. M. Devor, P.D. Wall, and N. Catalan Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction PAIN® 48 1992 261 268
18. H. Ehrsson, K. Wiech, N. Weiskopf, R.J. Dolan, and R.E. Passingham Threatening a rubber hand that you feel is yours elicits a cortical anxiety response Proc Natl Acad Sci U S A 104 2007 9828 9833
19. B.M. Faggin, K.T. Nguyen, and M.A. Nicolelis Immediate and simultaneous sensory reorganization at cortical and subcortical levels of the somatosensory system Proc Natl Acad Sci U S A 94 1997 9428 9433
20. N.B. Finnerup, L. Nikolajsen, and T.S. Jensen Are we neglecting spinal reorganization following nerve damage? PAIN® 153 2012 269 272
21. N.B. Finnerup, C. Norrbrink, A. Fuglsang-Frederiksen, A.J. Terkelsen, A.P. Hojlund, and T.S. Jensen Pain, referred sensations, and involuntary muscle movements in brachial plexus injury Acta Neurol Scand 121 2010 320 327
22. H. Flor, T. Elbert, S. Knecht, C. Wienbruch, C. Pantev, N. Birbaumer, W. Larbig, and E. Taub Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation Nature 375 1995 482 484
23. H. Flor, L. Nikolajsen, and T. Staehelin Jensen Phantom limb pain: a case of maladaptive CNS plasticity? Nat Rev Neurosci 7 2006 873 881
24. S.L. Florence, T.A. Hackett, and F. Strata Thalamic and cortical contributions to neural plasticity after limb amputation J Neurophysiol 83 2000 3154 3159
25. S.L. Florence, and J.H. Kaas Large-scale reorganization at multiple levels of the somatosensory pathway follows therapeutic amputation of the hand in monkeys J Neurosci 15 1995 8083 8095
26. S.A. Greenberg The history of dermatome mapping Arch Neurol 60 2003 126 131
27. J. Halbert, M. Crotty, and I.D. Cameron Evidence for the optimal management of acute and chronic phantom pain: a systematic review Clin J Pain 18 2002 84 92
28. A.J. Harris Cortical origin of pathological pain Lancet 354 1999 1464 1466
29. W.R. Henderson, and G.E. Smyth Phantom limbs J Neurol Neurosurg Psychiatry 11 1948 88 112
30. W. Jenkins, M. Merzenich, M. Ochs, T. Allard, and E. Guíc-Robles Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation J Neurophysiol 63 1990 82 104
31. E.G. Jones Cortical and subcortical contributions to activity-dependent plasticity in primate somatosensory cortex Annu Rev Neurosci 23 2000 1 37
32. J. Kaas, M. Merzenich, and H. Killackey The reorganization of somatosensory cortex following peripheral nerve damage in adult and developing mammals Ann Rev Neurosci 6 1983 325 356
33. K.C. Kajander, S. Wakisaka, and G.J. Bennett Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat Neurosci Lett 138 1992 225 228
34. J. Katz, and R. Melzack Pain, "memories" in phantom limbs: review and clinical observations PAIN® 43 1990 319 336
35. J.J. Keegan, and F.D. Garrett The segmental distribution of the cutaneous nerves in the limbs of man Anat Rec 102 1948 409 437
36. W.S. Kingery, G.S. Agashe, S. Sawamura, M.F. Davies, J.D. Clark, and M. Maze Glucocorticoid inhibition of neuropathic hyperalgesia and spinal Fos Anesth Analg 92 2001 476 482
37. E. Kirk Impulses in dorsal spinal nerve rootlets in cats and rabbits arising from dorsal root ganglia isolated from the periphery J Comp Neurol 2 1974 165 176
38. E.J. Kirk, and D. Denny-Brown Functional variation in dermatomes in the macaque monkey following dorsal root lesions J Comp Neurol 139 1970 307 320
39. H. Knotkova, R.A. Cruciani, V.M. Tronnier, and D. Rasche Current and future options for the management of phantom-limb pain J Pain Res 5 2012 39 49
40. S. Kuslich, C. Ulstro, and C. Michael The tissue origin of low back pain and sciatica Orth Clin North Am 22 1991 181 187
41. J.Y. Li, W. Xie, J.A. Strong, Q.L. Guo, and J.M. Zhang Mechanical hypersensitivity, sympathetic sprouting, and glial activation are attenuated by local injection of corticosteroid near the lumbar ganglion in a rat model of neuropathic pain Reg Anesth Pain Med 36 2011 56 62
42. C.N. Liu, P.D. Wall, E. Ben-Dor, M. Michaelis, R. Amir, and M. Devor Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury PAIN® 85 2000 503 521
43. J.D. Loeser, A.A. Ward, and L.E. White Chronic deafferentation of human spinal cord neurons J Neurosurg 29 1968 48 50
44. P. Lund Principles and practice of spinal anesthesia 1971 Charles C. Thomas Springfield
45. Makin TR, Scholz J, Filippini N, Henderson Slater D, Tracey I, Johansen-Berg H. Phantom pain is associated with preserved structure and function in the former hand area. Nat Commun 2013;4:1570.
46. R. Melzack Phantom limbs, the self and the brain Can Psychol 30 1989 1 16
47. G.L. Moseley, and P. Brugger Interdependence of movement and anatomy persists when amputees learn a physiologically impossible movement of their phantom limb Proc Natl Acad Sci U S A 106 2009 18798 18802
48. G.L. Moseley, A. Gallace, and C. Spence Is mirror therapy all it is cracked up to be? Current evidence and future directions PAIN® 138 2008 7 10
49. M. Nordin, B. Nyström, U. Wallin, and K.E. Hagbarth Ectopic sensory discharges and paresthesiae in patients with disorders of peripheral nerves, dorsal roots and dorsal columns PAIN® 20 1984 231 245
50. B. Nystrom, and K. Hagbarth Microelectrode recordings from transected nerves in amputees with phantom limb pain Neurosci Lett 27 1981 211 216
51. W. Penfield, and T. Rasmussen The cerebral cortex of man 1955 Macmillan New York
52. G.M. Pitcher, and J.L. Henry Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy Exp Neurol 214 2008 219 228
53. V. Ramachandran, M. Stewart, and D. Rogers-Ramachandran Perceptual correlates of massive cortical reorganization Neuroreport 3 1992 583 586
54. R. Sherman, M. Devor, C. Jones, J. Katz, and J. Marbach Phantom pain 1996 Plenum New York
55. R.A. Sherman, and J.G. Arena Phantom limb pain: mechanisms, incidence and treatment Rev Phys Med 4 1992 1 26
56. R.A. Sherman, V.D. Griffin, C.B. Evans, and A.S. Grana Temporal relationships between changes in phantom limb pain intensity and changes in surface electromyogram of the residual limb Int J Psychophysiol 13 1992 71 77
57. P. Soros, S. Knecht, C. Bantel, T. Imai, R. Wüsten, C. Pantev, B. Lütkenhöner, H. Bürkle, and H. Henningsen Functional reorganization of the human primary somatosensory cortex after acute pain demonstrated by magnetoencephalography Neurosci Lett 298 2001 195 198
58. T.S. Szasz Pain and pleasure: a study of bodily feeling 1957 Basic Books New York
59. D.L. Tanelian, and M.B. MacIver Analgesic concentrations of lidocaine suppress tonic A-delta and C-fiber discharges produced by acute injury Anesthesia 74 1991 934 936
60. M.J. Tessler, and S.J. Kleiman Spinal anaesthesia for patients with previous lower limb amputations Anaesthesia 49 1994 439 441
61. T.D. Waberski, R. Gobbelé, W. Kawohl, C. Cordes, and H. Buchner Immediate cortical reorganization after local anesthetic block of the thumb: source localization of somatosensory evoked potentials in human subjects Neurosci Lett 347 2003 151 154
62. P.D. Wall, and M. Devor Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats PAIN® 17 1983 321 339
63. P.D. Wall, and M. Gutnick Properties of afferent nerve impulses originating from a neuroma Nature 248 1974 740 743
64. M.S. Wallace, J.B. Dyck, S.S. Rossi, and T.L. Yaksh Computer-controlled lidocaine infusion for the evaluation of neuropathic pain after peripheral nerve injury PAIN® 66 1996 69 77
65. C.J. Woolf, and M.W. Salter Plasticity and pain: role of the dorsal horn S.B. McMahon, M. Koltzenberg, Wall and Melzack's textbook of pain 5th ed. 2006 Elsevier Churchill Livingstone London 91 105
66. T.T. Yang, C.C. Gallen, V.S. Ramachandran, S. Cobb, B.J. Schwartz, and F.E. Bloom Noninvasive detection of cerebral plasticity in adult human somatosensory cortex Neuroreport 5 1994 701 704