In vitro characterization of a peripheral afferent pathway of the rat after chronic sciatic nerve section

Journal of Neurophysiology

Volumn 76, Issue 5, 1996, Pages 3169-3177

  Babbedge, Rachel C ^a   Soper, Amanda J ^a   Gentry, Clive T ^a   Hood, Vivianne C ^a   Campbell, Elizabeth A ^a   Urban, Laszlo ^a  

^a Sandoz Institute for Medical Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; FREQUENCY ANALYSIS; MALE; NERVE INJURY; NEURECTOMY; NONHUMAN; PRIMARY AFFERENT DEPOLARIZATION; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SENSORY NERVE; SPINAL GANGLION;

EID: 0029970810     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.76.5.3169     Document Type: Article

References (43)

1. ALDSKOGIUS, H., AVIDSSON, J., AND GRANT, G. Axotomy induced changes in primary sensory neurons. In: Sensory Neurons: Diversity, Development, and Plasticity, edited by S. A. Scott. London: Oxford University Press, 1992, p. 363-383.
2. BABBEDGE, R. C., DRAY, A., AND URBAN, L. Complex regional pain syndromes (CRPS): mechanisms and therapy from experimental models of peripheral nerve injury. Pain Rev. 2: 298-309, 1996.
3. BELMONTE, C, GALLEGO, R., AND MORALES, A. Membrane properties of primary sensory neurons of the cat after peripheral reinnervation. J. Physiol. Lond 405: 219-232, 1988.
4. BENNETT, G. Neuropathic pain. In: The Textbook of Pain, edited by P. D. Wall and R. Melzack. New York: Churchill Livingstone, 1994, p. 201-224.
5. BENNETT, G. J. AND XIE, Y.-K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33: 87-107, 1988.
6. BIELLA, G. AND SOTGIU, M. L. Central effects of systemic lidocaine mediated by glycine spinal receptors: an iontophoretic study in the rat spinal cord. Brain Res. 603: 201-206, 1993.
7. BLUMBERG, W. AND JÄNIG, W. Discharge pattern of afferent fibers from a neuroma. Pain 20: 335-353, 1984.
8. BURCHIEL, K. J. AND RUSSEL, L. C. Has the amount of spontaneous electrical activity in experimental neuromas been overestimated? Somatosens. Res. 5: 63-75, 1987.
9. CALVIN, W. H., DEVOR, M., AND HOWE, J. W. Can neuralgias arise from minor demyelination? Spontaneous firing, mechanosensitivity, and after-discharge from conducting axons. Exp. Neurol. 75: 55-63, 1982.
10. CHABAL, C., JACOBSON, L., RUSSEL, L. C., AND BURCHIEL, K. J. Pain in response to perineuromal injection of normal saline, epinephrine, and lidocaine in humans. Pain 49: 9-12, 1992.
11. CHAPLAN, S. R., BACH, F. W., SHAFER, S. L., AND YAKSH, T. L. Prolonged alleviation of tactile allodynia by intravenous lidocaine in neuropathic rats. Anesthesiology 83: 775-785, 1995.
12. DEVOR, M. The pathophysiology of damaged peripheral nerves. In: The Textbook of Pain, edited by P. D. Wall and R. Melzack. New York: Churchill Livingstone, 1994, p. 79-100.
13. DEVOR, M., JÄNIG, W., AND MICHAELIS, M. Modulation of activity in dorsal root ganglion neurons by sympathetic activation in nerve-injured rats. J. Neurophysiol. 71: 38-47, 1994.
14. GALLEGO, R., IVORRA, I., AND MORALES, A. Effects of central or peripheral axotomy on membrane properties of sensory neurons in the petrosal ganglion of the cat. J. Physiol. Lond. 391: 39-56, 1987.
15. GOVRIN-LIPPMANN, R. AND DEVOR, M. Ongoing activity in severed nerve sources and variation with time. Brain Res. 159: 406-410, 1978.
16. GRACELY, R.H., LYNCH, S.A. AND BENNETT, G. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain 51: 175-194, 1992.
17. GURTU, S. AND SMITH, P. A. Electrophysiological characteristics of hamster dorsal root ganglion cells and their response to axotomy. J. Neurophysiol. 59: 408-423, 1988.
18. HAO, J.-X. AND WIESENFELD-HALLIN, Z. Variability in the occurrence of ongoing discharges in primary afferents originating in the neuroma after peripheral nerve section in different strains of rats. Neurosci. Lett. 169: 119-121, 1994.
19. HÖKFELT, T., ZHANG, X., AND WIESENFELD-HALLIN, Z. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci. 17: 22-30, 1994.
20. JÄNIG, W. Pathophysiology of nerve following mechanical injury. In: Proceedings of the Vth World Congress on Pain, edited by R. Dubner, G. F. Gebhart, and M. R. Bond. New York: Elsevier Science Publishers, 1988, chapt. 11.
21. KAJANDER, K. C. AND BENNETT, G. J. Onset of painful peripheral neuropathy in rat: a partial differential deafferentation and spontaneous discharge in A-beta and A-delta primary afferent neurons. J. Neurophysiol. 68: 734-744, 1992.
22. KAJANDER, K. C., WAKISAKA, S., AND BENNETT, G. J. Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat. Neurosci. Lett. 138: 225-228, 1992.
23. KIM, S. H. AND CHUNG, J. M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50: 355-363, 1992.
24. + channels. J. Neurophysiol. 72: 349-359, 1994.
25. MCLACHLAN, E. M., JÄNIG, W., DEVOR, M., AND MICHAELIS, M. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature Lond. 363: 543-546, 1993.
26. MICHAELIS, M., BLENK, K. H., JÄNIG, W., AND VOGEL, C. Development of spontaneous activity and mechanosensitivity in axotomised afferent nerve fibers during the first hours after nerve transection in rats. J. Neurophysiol. 74: 1020-1027, 1996.
27. NA, H. S., HAN, J. S., KO, K. H., AND HONG, S. K. A behavioural peripheral neuropathy produced in rat tail by inferior caudal trunk injury. Neurosci. Lett. 177: 50-52, 1994.
28. NAGY, I. AND WOOLF, C. J. Lignocaine selectively reduces C fiber-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics. Pain 64: 59-70, 1996.
29. SATO, J. AND PERL, E. R. Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury. Science Wash. DC 251: 1608-1610, 1991.
30. SCADDING, J. W. The development of ongoing activity, mechanosensitivity and adrenaline sensitivity in severed peripheral axons. Exp. Neurol. 73: 345-364, 1981.
31. SELTZER, Z., DUBNER, R., AND SHIR, Y. A novel behavioural model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43: 205-218, 1990.
32. SHEEN, K. AND CHUNG, J. M. Signs of neuropathic pain depend on signals from injured nerve fibers in a rat model. Brain Res. 610: 62-68, 1993.
33. TRACEY, D. J., ROMM, M. A., AND YAO, N. M. Peripheral hyperalgesia in experimental neuropathy: exacerbation by neuropeptide Y. Brain Res. 669: 245-254, 1995.
34. WALL, P. D. AND DEVOR, M. Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. Pain 17: 321-329, 1983.
35. WALL, P. D., DEVOR, M., INBAL, R., SCADDING, J. W., SCHOFIELD, D., SELTZER, Z., AND TOMKIEWICZ, M. M. Autotomy following peripheral nerve lesions: experimental anaesthesia dolorosa. Pain 7: 103-113, 1979.
36. WALL, P. D. AND GUTNICK, M. Properties of afferent nerve impulses originating from a neuroma. Nature Lond. 248: 740-743, 1974.
37. WELK, E., LEAH, J. D,. AND ZIMMERMANN, M. Characteristics of A- and C- fibers ending in a sensory nerve neuroma in the rat. J. Neurophysiol. 63: 759-765, 1990.
38. WIESENFELD, Z. AND LINDBLOM, U. Behavioural and electrophysiological effects of various types of peripheral nerve lesions in the rat: a comparison of models for chronic pain. Pain 8: 283-298, 1980.
39. WILLIS, W. D. AND COGGESHALL, R. E. Sensory Mechanisms of the Spinal Cord (2nd ed.). New York: Plenum Press, 1991.
40. WOOLF, C. J. AND DOUBELL, T. P. The pathophysiology of chronic pain: increased sensitivity to low threshold A beta-fiber inputs. Curr. Opin. Neurobiol. 4: 525-534, 1995.
41. WOOLF, C. J., SHORTLAND, P., AND COGGESHALL, R. E. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature Lond. 355: 75-77, 1992.
42. XIE, F., ZHANG, J., PETERSEN, M., AND LAMOTTE, R. H. Funtional changes in dorsal root ganglion cells after chronic nerve constriction in the rat. J. Neurophysiol. 73: 1811-1820, 1995.
43. ZHANG, J. AND LAMOTTE, R. H. Abnormal spontaneous activity and adrenergic sensitivity in intact nerve-injured dorsal root ganglion cells in vitro. Soc. Neurosci. Abstr. 158.3: 383, 1995.