Diet-induced obesity may affect the uterine immune environment in early-mid pregnancy, reducing NK-cell activity and potentially compromising uterine vascularization

International Journal of Obesity

Volumn 38, Issue 6, 2014, Pages 766-774

  Parker, V J ^a   Solano, M E ^b   Arck, P C ^b   Douglas, A J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

cytokines; IFN ; immune milieu; mice; pregnancy

Indexed keywords

GAMMA INTERFERON; PROGESTERONE; PROLACTIN;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CD8+ T LYMPHOCYTE; CELL COUNT; CELLULAR IMMUNITY; DISEASE MODEL; FEMALE; FIRST TRIMESTER PREGNANCY; FLOW CYTOMETRY; IMMUNOASSAY; INFANT; INGUINAL LYMPH NODE; LEUKOCYTE; LIPID DIET; LYMPHOCYTE COUNT; MALE; MATERNAL OBESITY; MOUSE; MOUSE MODEL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROGESTERONE RELEASE; PROLACTIN BLOOD LEVEL; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY; UTERINE BLOOD VESSEL; UTERUS BLOOD FLOW; ADVERSE EFFECTS; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; COMPLICATION; FETOMATERNAL TRANSFUSION; FETUS; GENE EXPRESSION REGULATION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; OBESITY; PATHOLOGY; PREGNANCY; SECRETION (PROCESS); UTERUS;

MUS;

ANALYSIS OF VARIANCE; ANIMALS; DIET, HIGH-FAT; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNE TOLERANCE; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MATERNAL-FETAL EXCHANGE; MICE; MICE, INBRED C57BL; OBESITY; PREGNANCY; PROGESTERONE; UTERUS;

EID: 84902259727     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2013.164     Document Type: Article

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