MAdCAM-1 expressing sacral lymph node in the lymphotoxin β-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infection

Journal of Immunology

Volumn 173, Issue 3, 2004, Pages 1908-1913

  Soderberg, Kelly A ^a   Linehan, Melissa M ^a   Ruddle, Nancy H ^a   Iwasaki, Akiko ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN G; LYMPHOTOXIN; LYMPHOTOXIN BETA; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CERVICAL LYMPH NODE; CONTROLLED STUDY; FEMALE; HERPES; HERPES SIMPLEX VIRUS 2; ILIAC ARTERY; IMMUNE RESPONSE; LYMPH NODE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; ORGANOGENESIS; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 3242805019     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.3.1908     Document Type: Article

References (26)

1. Mebius, R. E. 2003. Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3:292.
2. Gommerman, J. L., and J. L. Browning. 2003. Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease. Nat. Rev. Immunol. 3:642.
3. Sacca, R., A. Kratz, A. Campos-Neto, M. S. Hanson, and N. H. Ruddle. 1995. Lymphotoxin: from chronic inflammation to lymphoid organs. J. Inflamm. 47:81.
4. Koni, P. A., R. Sacca, P. Lawton, J. L. Browning, N. H. Ruddle, and R. A. Flavell. 1997. Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity 6:491.
5. Fu, Y. X., G. Huang, M. Matsumoto, H. Molina, and D. D. Chaplin. 1997. Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph node. Proc. Natl. Acad. Sci. USA 94:5739.
6. Banks, T. A., B. T. Rouse, M. K. Kerley, P. J. Blair, V. L. Godfrey, N. A. Kuklin, D. M. Bouley, J. Thomas, S. Kanangat, and M. L. Mucenski. 1995. Lymphotoxin-α-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol 155:1685.
7. De Togni, P., J. Goellner, N. H. Ruddle, P. R. Streeter, A. Pick, S. Mariathasan, S. C. Smith, R. Carlson, L. P. Shornick, J. Strauss-Schoenberger, et al. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703.
8. Alimzhanov, M. B., D. V. Kuprash, M. H. Kosco-Vilbois, A. Luz, R. L. Turetskaya, A. Tarakhovsky, K. Rajewsky, S. A. Nedospasov, and K. Pfeffer. 1997. Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice. Proc. Natl. Acad. Sci. USA 94:9302.
9. Drayton, D. L., X. Ying, J. Lee, W. Lesslauer, and N. H. Ruddle. 2003. Ectopic LTαβ directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase. J. Exp. Med. 197:1153.
10. Cuff, C. A., J. Schwartz, C. M. Bergman, K. S. Russell, J. R. Bender, and N. H. Ruddle. 1998. Lymphotoxin α3 induces chemokines and adhesion molecules: insight into the role of LTα in inflammation and lymphoid organ development. J. Immunol. 161:6853.
11. - cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93:11019.
12. McDermott, M. R., C. H. Goldsmith, K. L. Rosenthal, and L. J. Brais. 1989. T lymphocytes in genital lymph nodes protect mice from intravaginal infection with herpes simplex virus type 2. J. Infect. Dis. 159:460.
13. Jones, C. A., T. J. Taylor, and D. M. Knipe. 2000. Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model. Virology 278:137.
14. Zhao, X., E. Deak, K. Soderberg, M. Linehan, D. Spezzano, J. Zhu, D. M. Knipe, and A. Iwasaki. 2003. Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2. J. Exp. Med. 197:153.
15. Warnock, R. A., S. Askari, E. C. Butcher, and U. H. von Andrian. 1998. Molecular mechanisms of lymphocyte homing to peripheral lymph nodes. J. Exp. Med. 187:205.
16. Kraal, G., and R. E. Mebius. 1997. High endothelial venules: lymphocyte traffic control and controlled traffic. Adv. Immunol. 65:347.
17. 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined, Immunity 3:99.
18. Girard, J. P., and T. A. Springer. 1995. High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol. Today 16:449.
19. Abe, K., F. O. Yarovinsky, T. Murakami, A. N. Shakhov, A. V. Tumanov, D. Ito, L. N. Drutskaya, K. Pfeffer, D. V. Kuprash, K. L. Komschlies, and S. A. Nedospasov. 2003. Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo. Blood 101:1477.
20. Futterer, A., K. Mink, A. Luz, M. H. Kosco-Vilbois. and K. Pfeffer. 1998. The lymphotoxin β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9:59.
21. Koni, P. A., and R. A. Flavell. 1998. A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymphotoxin β. J. Exp. Med. 187:1977.
22. Kuprash, D. V., M. B. Alimzhanov, A. V. Tumanov, A. O. Anderson, K. Pfeffer, and S. A. Nedospasov. 1999. TNF and lymphotoxin β cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes. J. Immunol. 163:6575.
23. Kuprash, D. V., M. B. Alimzhanov, A. V. Tumanov, S. I. Grivennikov, A. N. Shakhov, L. N. Drutskaya, M. W. Marino, R. L. Turetskaya, A. O. Anderson, K. Rajewsky, et al. 2002. Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice. Mol. Cell. Biol. 22:8626.
24. Drayton, D. L., K. Chan, W. Lesslauer, J. Lee, X. Y. Ying, and N. H. Ruddle. 2002. Lymphocyte traffic in lymphoid organ neogenesis: differential roles of Ltα and LTαβ. Adv. Exp. Med. Biol. 512:43.
25. Scheu, S., J. Alferink, T. Potzel, W. Barchet, U. Kalinke, and K. Pfeffer. 2002. Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin β in mesenteric lymph node genesis. J. Exp. Med. 195:1613.
26. Wang, Y., G. Huang, J. Wang, H. Molina, D. D. Chaplin, and Y. X. Fu. 2000. Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin. Eur. J. Immunol. 30:2226.