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Volumn 2014, Issue , 2014, Pages

Low-dose decitabine-based chemoimmunotherapy for patients with refractory advanced solid tumors: A phase I/II report

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; IRINOTECAN; OXALIPLATIN; PEMETREXED; PREDNISONE; RITUXIMAB; VINCRISTINE; VINDESINE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; AZACITIDINE; DNA METHYLTRANSFERASE;

EID: 84902201862     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2014/371087     Document Type: Article
Times cited : (50)

References (38)
  • 1
  • 2
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • DOI 10.1002/path.1706
    • Longley D. B., Johnston P. G., Molecular mechanisms of drug resistance. Journal of Pathology 2005 205 2 275 292 2-s2.0-13644254794 10.1002/path.1706 (Pubitemid 40227997)
    • (2005) Journal of Pathology , vol.205 , Issue.2 , pp. 275-292
    • Longley, D.B.1    Johnston, P.G.2
  • 3
    • 64349095390 scopus 로고    scopus 로고
    • An operational definition of epigenetics
    • 2-s2.0-64349095390 10.1101/gad.1787609
    • Berger S. L., Kouzarides T., Shiekhattar R., Shilatifard A., An operational definition of epigenetics. Genes and Development 2009 23 7 781 783 2-s2.0-64349095390 10.1101/gad.1787609
    • (2009) Genes and Development , vol.23 , Issue.7 , pp. 781-783
    • Berger, S.L.1    Kouzarides, T.2    Shiekhattar, R.3    Shilatifard, A.4
  • 4
    • 74049141478 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • 2-s2.0-74049141478 10.1093/carcin/bgp220
    • Sharma S., Kelly T. K., Jones P. A., Epigenetics in cancer. Carcinogenesis 2009 31 1 27 36 2-s2.0-74049141478 10.1093/carcin/bgp220
    • (2009) Carcinogenesis , vol.31 , Issue.1 , pp. 27-36
    • Sharma, S.1    Kelly, T.K.2    Jones, P.A.3
  • 5
    • 78649383152 scopus 로고    scopus 로고
    • Cancer epigenetics
    • 2-s2.0-78649383152 10.3322/caac.20085
    • Taby R., Issa J.-P., Cancer epigenetics. CA Cancer Journal for Clinicians 2010 60 6 376 392 2-s2.0-78649383152 10.3322/caac.20085
    • (2010) CA Cancer Journal for Clinicians , vol.60 , Issue.6 , pp. 376-392
    • Taby, R.1    Issa, J.-P.2
  • 6
    • 84897056300 scopus 로고    scopus 로고
    • Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung
    • Gomes A., Reis-Silva M., Alarcao A., Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung. Revista Portuguesa de Pneumologia 2014 20 1 20 30
    • (2014) Revista Portuguesa de Pneumologia , vol.20 , Issue.1 , pp. 20-30
    • Gomes, A.1    Reis-Silva, M.2    Alarcao, A.3
  • 7
    • 84867783393 scopus 로고    scopus 로고
    • The role of DNA methylation in the pathogenesis and treatment of cancer
    • Peedicayil J., The role of DNA methylation in the pathogenesis and treatment of cancer. Current Clinical Pharmacology 2012 7 4 333 340
    • (2012) Current Clinical Pharmacology , vol.7 , Issue.4 , pp. 333-340
    • Peedicayil, J.1
  • 8
    • 84893296472 scopus 로고    scopus 로고
    • Multiple MAGE-A genes as surveillance marker for the detection of circulating tumor cells in patients with ovarian cancer
    • Sang M., Wu X., Fan X., Multiple MAGE-A genes as surveillance marker for the detection of circulating tumor cells in patients with ovarian cancer. Biomarkers 2014 19 1 34 42
    • (2014) Biomarkers , vol.19 , Issue.1 , pp. 34-42
    • Sang, M.1    Wu, X.2    Fan, X.3
  • 9
    • 76549092572 scopus 로고    scopus 로고
    • 5-Azacitidine prolongs overall survival in patients with myelodysplastic syndrome - A systematic review and meta-analysis
    • 2-s2.0-76549092572 10.3324/haematol.2009.010611
    • Gurion R., Vidal L., Gafter-Gvili A., Yeshurun Y. B., Raanani P., Shpilberg O., 5-Azacitidine prolongs overall survival in patients with myelodysplastic syndrome-a systematic review and meta-analysis. Haematologica 2010 95 2 303 310 2-s2.0-76549092572 10.3324/haematol.2009.010611
    • (2010) Haematologica , vol.95 , Issue.2 , pp. 303-310
    • Gurion, R.1    Vidal, L.2    Gafter-Gvili, A.3    Yeshurun, Y.B.4    Raanani, P.5    Shpilberg, O.6
  • 10
    • 77449149374 scopus 로고    scopus 로고
    • Multicenter, phase II study of decitabine for the first-line treatment of older patients with Acute Myeloid Leukemia
    • 2-s2.0-77449149374 10.1200/JCO.2009.23.9178
    • Cashen A. F., Schiller G. J., O'Donnell M. R., DiPersio J. F., Multicenter, phase II study of decitabine for the first-line treatment of older patients with Acute Myeloid Leukemia. Journal of Clinical Oncology 2010 28 4 556 561 2-s2.0-77449149374 10.1200/JCO.2009.23.9178
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.4 , pp. 556-561
    • Cashen, A.F.1    Schiller, G.J.2    O'Donnell, M.R.3    Dipersio, J.F.4
  • 11
    • 84883306098 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors and their emerging role in epigenetic therapy of cancer
    • Gnyszka A., Jastrzebski Z., Flis S., DNA methyltransferase inhibitors and their emerging role in epigenetic therapy of cancer. Anticancer Research 2013 33 8 2989 2996
    • (2013) Anticancer Research , vol.33 , Issue.8 , pp. 2989-2996
    • Gnyszka, A.1    Jastrzebski, Z.2    Flis, S.3
  • 12
    • 77957937450 scopus 로고    scopus 로고
    • Epigenetic modifications as therapeutic targets
    • 2-s2.0-77957937450 10.1038/nbt.1678
    • Kelly T. K., de Carvalho D. D., Jones P. A., Epigenetic modifications as therapeutic targets. Nature Biotechnology 2010 28 10 1069 1078 2-s2.0-77957937450 10.1038/nbt.1678
    • (2010) Nature Biotechnology , vol.28 , Issue.10 , pp. 1069-1078
    • Kelly, T.K.1    De Carvalho, D.D.2    Jones, P.A.3
  • 14
    • 84877355904 scopus 로고    scopus 로고
    • Low dose decitabine treatment induces CD80 expression in cancer cells and stimulates tumor specific cytotoxic T Lymphocyte Responses
    • e62924
    • Wang L.-X., Mei Z.-Y., Zhou J.-H., Low dose decitabine treatment induces CD80 expression in cancer cells and stimulates tumor specific cytotoxic T Lymphocyte Responses. PLoS ONE 2013 8 5 e62924
    • (2013) PLoS ONE , vol.8 , Issue.5
    • Wang, L.-X.1    Mei, Z.-Y.2    Zhou, J.-H.3
  • 15
    • 17444452612 scopus 로고    scopus 로고
    • Low-dose 5-Aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter phase II study in elderly patients
    • Wijermans P., Lübbert M., Verhoef G., Bosly A., Ravoet C., Andre M., Ferrant A., Low-dose 5-Aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients. Journal of Clinical Oncology 2000 18 5 956 962 2-s2.0-17444452612 (Pubitemid 30123770)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.5 , pp. 956-962
    • Wijermans, P.1    Lubbert, M.2    Verhoef, G.3    Bosly, A.4    Ravoet, C.5    Andre, M.6    Ferrant, A.7
  • 17
    • 84872316231 scopus 로고    scopus 로고
    • Phase i study of 5-aza-2′-deoxycytidine in combination with valproic acid in non-small-cell lung cancer
    • Chu B. F., Karpenko M. J., Liu Z., Phase I study of 5-aza-2′- deoxycytidine in combination with valproic acid in non-small-cell lung cancer. Cancer Chemotherapy and Pharmacology 2013 71 1 115 121
    • (2013) Cancer Chemotherapy and Pharmacology , vol.71 , Issue.1 , pp. 115-121
    • Chu, B.F.1    Karpenko, M.J.2    Liu, Z.3
  • 18
    • 84872224552 scopus 로고    scopus 로고
    • Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions
    • Kopp L. M., Ray A., Denman C. J., Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions. Molecular Immunology 2013 54 3-4 296 301
    • (2013) Molecular Immunology , vol.54 , Issue.3-4 , pp. 296-301
    • Kopp, L.M.1    Ray, A.2    Denman, C.J.3
  • 19
    • 84893207600 scopus 로고    scopus 로고
    • Autologous CIK cell immunotherapy in patients with renal cell carcinoma after radical nephrectomy
    • 195691 10.1155/2013/195691
    • Zhang Y., Wang J., Wang Y., Autologous CIK cell immunotherapy in patients with renal cell carcinoma after radical nephrectomy. Clinical and Developmental Immunology 2013 2013 12 195691 10.1155/2013/195691
    • (2013) Clinical and Developmental Immunology , vol.2013 , pp. 12
    • Zhang, Y.1    Wang, J.2    Wang, Y.3
  • 20
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M., Corn P. G., Baylin S. B., Herman J. G., A gene hypermethylation profile of human cancer. Cancer Research 2001 61 8 3225 3229 2-s2.0-0035870248 (Pubitemid 32695003)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 21
    • 33845712622 scopus 로고    scopus 로고
    • Epigenetics and the plasticity of differentiation in normal and cancer stem cells
    • DOI 10.1038/sj.onc.1209816, PII 1209816
    • Lotem J., Sachs L., Epigenetics and the plasticity of differentiation in normal and cancer stem cells. Oncogene 2006 25 59 7663 7672 2-s2.0-33845712622 10.1038/sj.onc.1209816 (Pubitemid 44967961)
    • (2006) Oncogene , vol.25 , Issue.59 , pp. 7663-7672
    • Lotem, J.1    Sachs, L.2
  • 23
    • 76249090605 scopus 로고    scopus 로고
    • Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer
    • 2-s2.0-76249090605
    • Chun S. G., Zhou W., Yee N. S., Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer. Cancer Biology & Therapy 2009 8 14 1328 1339 2-s2.0-76249090605
    • (2009) Cancer Biology & Therapy , vol.8 , Issue.14 , pp. 1328-1339
    • Chun, S.G.1    Zhou, W.2    Yee, N.S.3
  • 24
    • 33746917919 scopus 로고    scopus 로고
    • Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: A novel method to potentiate natural killer cell tumor cytotoxicity
    • DOI 10.1158/0008-5472.CAN-06-0680
    • Lundqvist A., Abrams S. I., Schrump D. S., Alvarez G., Suffredini D., Berg M., Childs R., Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Research 2006 66 14 7317 7325 2-s2.0-33746917919 10.1158/0008-5472.CAN-06-0680 (Pubitemid 44197714)
    • (2006) Cancer Research , vol.66 , Issue.14 , pp. 7317-7325
    • Lundqvist, A.1    Abrams, S.I.2    Schrump, D.S.3    Alvarez, G.4    Suffredini, D.5    Berg, M.6    Childs, R.7
  • 25
    • 34250621776 scopus 로고    scopus 로고
    • Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: Immunotherapeutic implications
    • DOI 10.1158/1078-0432.CCR-06-3091
    • Fonsatti E., Nicolay H. J. M., Sigalotti L., Calabrò L., Pezzani L., Colizzi F., Altomonte M., Guidoboni M., Marincola F. M., Maio M., Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. Clinical Cancer Research 2007 13 11 3333 3338 2-s2.0-34250621776 10.1158/1078-0432.CCR-06-3091 (Pubitemid 46944920)
    • (2007) Clinical Cancer Research , vol.13 , Issue.11 , pp. 3333-3338
    • Fonsatti, E.1    Nicolay, H.J.M.2    Sigalotti, L.3    Calabro, L.4    Pezzani, L.5    Colizzi, F.6    Altomonte, M.7    Guidoboni, M.8    Marincola, F.M.9    Maio, M.10
  • 27
    • 79952050717 scopus 로고    scopus 로고
    • Safety and efficacy of azacitidine in myelodysplastic syndromes
    • 2-s2.0-79952050717 10.2147/DDDT.S3143
    • Vigil C. E., Martin-Santos T., Garcia-Manero G., Safety and efficacy of azacitidine in myelodysplastic syndromes. Drug Design, Development and Therapy 2010 4 221 229 2-s2.0-79952050717 10.2147/DDDT.S3143
    • (2010) Drug Design, Development and Therapy , vol.4 , pp. 221-229
    • Vigil, C.E.1    Martin-Santos, T.2    Garcia-Manero, G.3
  • 29
    • 77957039745 scopus 로고    scopus 로고
    • Phase i study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: A children's oncology group study
    • 2-s2.0-77957039745 10.1002/pbc.22607
    • George R. E., Lahti J. M., Adamson P. C., Zhu K., Finkelstein D., Ingle A. M., Reid J. M., Krailo M., Neuberg D., Blaney S. M., Diller L., Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a children's oncology group study. Pediatric Blood and Cancer 2010 55 4 629 638 2-s2.0-77957039745 10.1002/pbc.22607
    • (2010) Pediatric Blood and Cancer , vol.55 , Issue.4 , pp. 629-638
    • George, R.E.1    Lahti, J.M.2    Adamson, P.C.3    Zhu, K.4    Finkelstein, D.5    Ingle, A.M.6    Reid, J.M.7    Krailo, M.8    Neuberg, D.9    Blaney, S.M.10    Diller, L.11
  • 31
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • 2-s2.0-33644856123 10.1038/nrd1930
    • Yoo C. B., Jones P. A., Epigenetic therapy of cancer: past, present and future. Nature Reviews Drug Discovery 2006 5 1 37 50 2-s2.0-33644856123 10.1038/nrd1930
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.1 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 32
    • 34250213859 scopus 로고    scopus 로고
    • DNA methylation as a therapeutic target in cancer
    • DOI 10.1158/1078-0432.CCR-06-2076
    • Issa J.-P. J., DNA methylation as a therapeutic target in cancer. Clinical Cancer Research 2007 13 6 1634 1637 2-s2.0-34250213859 10.1158/1078-0432.CCR-06-2076 (Pubitemid 46952927)
    • (2007) Clinical Cancer Research , vol.13 , Issue.6 , pp. 1634-1637
    • Issa, J.-P.J.1
  • 33
    • 52049102456 scopus 로고    scopus 로고
    • Evolution of decitabine development: Accomplishments, ongoing investigations, and future strategies
    • 2-s2.0-52049102456 10.1002/cncr.23463
    • Jabbour E., Issa J.-P., Garcia-Manero G., Kantarjian H., Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. Cancer 2008 112 11 2341 2351 2-s2.0-52049102456 10.1002/cncr.23463
    • (2008) Cancer , vol.112 , Issue.11 , pp. 2341-2351
    • Jabbour, E.1    Issa, J.-P.2    Garcia-Manero, G.3    Kantarjian, H.4
  • 34
    • 84879783987 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic analysis of 5-aza-2′- deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy
    • Karahoca M., Momparler R. L., Pharmacokinetic and pharmacodynamic analysis of 5-aza-2′-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy. Clin Epigenetics 2013 5 1, article 3
    • (2013) Clin Epigenetics , vol.5 , Issue.1 ARTICLE 3
    • Karahoca, M.1    Momparler, R.L.2
  • 37
    • 84904757855 scopus 로고    scopus 로고
    • Decitabine facilitates immune recognition of sarcoma cells by upregulating CT antigens, MHC molecules, and ICAM-1
    • 10.1007/s13277-014-1764-9
    • Krishnadas D. K., Bao L., Bai F., Decitabine facilitates immune recognition of sarcoma cells by upregulating CT antigens, MHC molecules, and ICAM-1. Tumor Biology 2014 10.1007/s13277-014-1764-9
    • (2014) Tumor Biology
    • Krishnadas, D.K.1    Bao, L.2    Bai, F.3
  • 38
    • 0035799382 scopus 로고    scopus 로고
    • Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
    • Santini V., Kantarjian H. M., Issa J.-P., Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Annals of Internal Medicine 2001 134 7 573 586 2-s2.0-0035799382 (Pubitemid 32245319)
    • (2001) Annals of Internal Medicine , vol.134 , Issue.7 , pp. 573-586
    • Santini, V.1    Kantarjian, H.M.2    Issa, J.-P.3


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