Platelet rich plasma enhances osteoconductive properties of a hydroxyapatite-β-tricalcium phosphate scaffold (Skelite™) for late healing of critical size rabbit calvarial defects

Journal of Cranio-Maxillofacial Surgery

Volumn 42, Issue 5, 2014, Pages

  El Backly, Rania M ^a,b   Zaky, Samer H ^a,b   Canciani, Barbara ^a   Saad, Manal M ^b,c   Eweida, Ahmed M ^b,d   Brun, Francesco ^e,f   Tromba, Giuliana ^f   Komlev, Vladimir S ^g   Mastrogiacomo, Maddalena ^a   Marei, Mona K ^b   Cancedda, Ranieri ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b University of Florida Health College of Medicine   (Egypt)

^c PHAROS UNIVERSITY IN ALEXANDRIA   (Egypt)

^d ALEXANDRIA UNIVERSITY   (Egypt)

^e UNIVERSITY OF TRIESTE   (Italy)

^f SINCROTRONE TRIESTE   (Italy)

^g BAIKOV INSTITUTE OF METALLURGY AND MATERIALS SCIENCE   (Russian Federation)

Author keywords

Bone regeneration; Critical size defect; Hydroxyapatite tricalcium phosphate scaffold; Local microenvironment; MicroCT phase analysis; Osteoconduction; Platelet rich plasma

Indexed keywords

COLLAGEN FIBER; HYDROXYAPATITE BETA TRICALCIUM PHOSPHATE; RESIN; SILICON; TISSUE SCAFFOLD; UNCLASSIFIED DRUG; CERAMICS; COLLAGEN; HYDROXYAPATITE; HYDROXYAPATITE-BETA TRICALCIUM PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE CONDUCTION; BONE MATRIX; BONE REGENERATION; CALVARIA; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL RABBIT; FRACTURE HEALING; IN VITRO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSTEOID; OSTEOPROGENITOR CELL; PERIOSTEUM; SKULL DEFECT; THROMBOCYTE RICH PLASMA; ANIMAL; BONE DEVELOPMENT; BONE DISEASES; CELL MOTION; CERAMICS; CHEMISTRY; HISTOLOGY; MESENCHYMAL STROMA CELL; OSTEOBLAST; PATHOLOGY; PHYSIOLOGY; PROCEDURES; RABBIT; SKULL; TIME; TISSUE ENGINEERING; TISSUE SCAFFOLD; TUMOR MICROENVIRONMENT; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; BONE DISEASES; BONE MATRIX; BONE REGENERATION; CELL MOVEMENT; CELLULAR MICROENVIRONMENT; CERAMICS; COLLAGEN; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HYDROXYAPATITES; MALE; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; OSTEOGENESIS; PLASTIC EMBEDDING; PLATELET-RICH PLASMA; RABBITS; SKULL; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; X-RAY MICROTOMOGRAPHY;

EID: 84902190602     PISSN: 10105182     EISSN: 18784119     Source Type: Journal    
DOI: 10.1016/j.jcms.2013.06.012     Document Type: Article

References (32)

1. M. Aaboe, E.M. Pinholt, and E. Hjorting-Hansen Healing of experimentally created defects: a review Br J Oral Maxillofac Surg 33 1995 312 318
2. N. Broggini, W. Hofstetter, E. Hunziker, D.D. Bosshardt, M.M. Bornstein, I. Seto, and et al The influence of PRP on early bone formation in membrane protected defects. A histological and histomorphometric study in the rabbit calvaria Clin Implant Dent Relat Res 13 2011 1 12
3. C.E. Dutra, M.M. Pereira, R. Serakides, and C.M. Rezende In vivo evaluation of bioactive glass foams associated with platelet-rich plasma in bone defects J Tissue Eng Regen Med 2 2008 221 227
4. R. El Backly, V. Ulivi, L. Tonachini, R. Cancedda, F. Descalzi, and M. Mastrogiacomo Platelet lysate induces in vitro wound healing of human keratinocytes associated with a strong proinflammatory response Tissue Eng Part A 17 2011 1787 1800
5. R.M. El Backly, S.H. Zaky, A. Muraglia, L. Tonachini, F. Brun, B. Canciani, and et al A platelet-rich plasma-based membrane as a periosteal substitute with enhanced osteogenic and angiogenic properties: a new concept for bone repair Tissue Eng Part A 19 2013 152 165
6. P.A. Everts, D. Delawi, C.B. Mahoney, A. van Erp, E.P. Overdevest, A. van Zundert, and et al Platelet leukocyte gel facilitates bone substitute growth and autologous bone growth in a goat model J Biomed Mater Res A 92 2010 746 753
7. A.F. Giovanini, T.M. Deliberador, C.C. Gonzaga, M.A. de Oliveira Filho, I. Gohringer, J. Kuczera, and et al Platelet-rich plasma diminishes calvarial bone repair associated with alterations in collagen matrix composition and elevated CD34+ cell prevalence Bone 46 2010 1597 1603
8. A.F. Giovanini, C.C. Gonzaga, J.C. Zielak, T.M. Deliberador, J. Kuczera, I. Goringher, and et al Platelet-rich plasma (PRP) impairs the craniofacial bone repair associated with its elevated TGF-beta levels and modulates the co-expression between collagen III and alpha-smooth muscle actin J Orthop Res 29 2011 457 463
9. A. Hokugo, Y. Sawada, R. Hokugo, H. Iwamura, M. Kobuchi, T. Kambara, and et al Controlled release of platelet growth factors enhances bone regeneration at rabbit calvaria Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104 2007 44 48
10. Y.J. Hwang, and J.Y. Choi Addition of mesenchymal stem cells to the scaffold of platelet-rich plasma is beneficial for the reduction of the consolidation period in mandibular distraction osteogenesis J Oral Maxillofac Surg 68 2010 1112 1124
11. P. Jungbluth, M. Wild, J.P. Grassmann, E. Ar, M. Sager, M. Herten, and et al Platelet-rich plasma on calcium phosphate granules promotes metaphyseal bone healing in mini-pigs J Orthop Res 28 2010 1448 1455
12. S.R. Kanthan, G. Kavitha, S. Addi, D.S. Choon, and T. Kamarul Platelet-rich plasma (PRP) enhances bone healing in non-united critical-sized defects: a preliminary study involving rabbit models Injury 42 2011 782 789
13. K. Kazakos, D.N. Lyras, V. Thomaidis, G. Agrogiannis, S. Botaitis, G. Drosos, and et al Application of PRP gel alone or in combination with guided bone regeneration does not enhance bone healing process: An experimental study in rabbits J Craniomaxillofac Surg 39 2011 49 53
14. E.S. Kim, J.J. Kim, and E.J. Park Angiogenic factor-enriched platelet-rich plasma enhances in vivo bone formation around alloplastic graft material J Adv Prosthodont 2 2010 7 13
15. E. Kon, G. Filardo, M. Delcogliano, M. Fini, F. Salamanna, G. Giavaresi, and et al Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model BMC Musculoskelet Disord 11 2010 220
16. L. Ma, L.W. Zheng, M.H. Sham, C.K. Lam, R.A. Zwahlen, and L.K. Cheung Effect of platelet-rich plasma on a rabbit model of nicotine-compromised bone healing J Oral Maxillofac Surg 69 2011 28 35
17. K.N. Malizos, and L.K. Papatheodorou The healing potential of the periosteum molecular aspects Injury 36 Suppl. 3 2005 S13 S19
18. R.E. Marx, E.R. Carlson, R.M. Eichstaedt, S.R. Schimmele, J.E. Strauss, and K.R. Georgeff Platelet-rich plasma: Growth factor enhancement for bone grafts Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85 1998 638 646
19. M. Mastrogiacomo, A. Papadimitropoulos, A. Cedola, F. Peyrin, P. Giannoni, S.G. Pearce, and et al Engineering of bone using bone marrow stromal cells and a silicon-stabilized tricalcium phosphate bioceramic: evidence for a coupling between bone formation and scaffold resorption Biomaterials 28 2007 1376 1384
20. R.E. Mooren, A.C. Dankers, M.A. Merkx, E.M. Bronkhorst, J.A. Jansen, and P.J. Stoelinga The effect of platelet-rich plasma on early and late bone healing using a mixture of particulate autogenous cancellous bone and Bio-Oss: an experimental study in goats Int J Oral Maxillofac Surg 39 2010 371 378
21. A. Naldini, E. Morena, M. Fimiani, G. Campoccia, V. Fossombroni, and F. Carraro The effects of autologous platelet gel on inflammatory cytokine response in human peripheral blood mononuclear cells Platelets 19 2008 268 274
22. M.A. Oliveira Filho, P.A. Nassif, O. Malafaia, J.M. Ribas Filho, C.A. Ribas, A.C. Camacho, and et al Effects of a highly concentrated platelet-rich plasma on the bone repair using non-critical defects in the calvaria of rabbits Acta Cir Bras 25 2010 28 33
23. N. Otsu A threshold selection method from grayscale histogram IEEE Transactions of the System, Man and Cybernetics 9 1979 62 66
24. A. Ozaki, M. Tsunoda, S. Kinoshita, and R. Saura Role of fracture hematoma and periosteum during fracture healing in rats: interaction of fracture hematoma and the periosteum in the initial step of the healing process J Orthop Sci 5 2000 64 70
25. A. Papadimitropoulos, M. Mastrogiacomo, F. Peyrin, E. Molinari, V.S. Komlev, F. Rustichelli, and et al Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: an X-ray computed microtomography study Biotechnol Bioeng 98 2007 271 281
26. R.S. Pessoa, S.R. Oliveira, H.H. Menezes, and D. de Magalhaes Effects of platelet-rich plasma on healing of alveolar socket: split-mouth histological and histometric evaluation in Cebus apella monkeys Indian J Dent Res 20 2009 442 447
27. A.S. Plachokova, J. van den Dolder, J.J. van den Beucken, and J.A. Jansen Bone regenerative properties of rat, goat and human platelet-rich plasma Int J Oral Maxillofac Surg 38 2009 861 869
28. J.D. Roh, R. Sawh-Martinez, M.P. Brennan, S.M. Jay, L. Devine, D.A. Rao, and et al Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling Proc Natl Acad Sci U S A 107 2010 4669 4674
29. S.E. Smith, and T.S. Roukis Bone and wound healing augmentation with platelet-rich plasma Clin Podiatr Med Surg 26 2009 559 588
30. P. Stockmann, J. Park, C. von Wilmowsky, E. Nkenke, E. Felszeghy, J.F. Dehner, and et al Guided bone regeneration in pig calvarial bone defects using autologous mesenchymal stem/progenitor cells - a comparison of different tissue sources J Craniomaxillofac Surg 40 2012 310 320
31. A.V. Volkov, I.S. Alekseeva, A.A. Kulakov, D.V. Gol'dshtein, S.A. Shustrov, A.I. Shuraev, and et al Regeneration of skull bones in adult rabbits after implantation of commercial osteoinductive materials and transplantation of a tissue-engineering construct Bull Exp Biol Med 149 2010 505 510
32. Y.D. Zhang, G. Wang, Y. Sun, and C.Q. Zhang Combination of platelet-rich plasma with degradable bioactive borate glass for segmental bone defect repair Acta Orthop Belg 77 2011 110 115