A platelet-rich plasma-based membrane as a periosteal substitute with enhanced osteogenic and angiogenic properties: A new concept for bone repair

Tissue Engineering - Part A

Volumn 19, Issue 1-2, 2013, Pages 152-165

  El Backly, Rania M ^a,b,c   Zaky, Samer H ^a,b   Muraglia, Anita ^d   Tonachini, Laura ^a,b   Brun, Francesco ^e,f   Canciani, Barbara ^a,b   Chiapale, Danilo ^b   Santolini, Federico ^b   Cancedda, Ranieri ^a,b   Mastrogiacomo, Maddalena ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c University of Florida Health College of Medicine   (Egypt)

^d Biorigen srl   (Italy)

^e UNIVERSITY OF TRIESTE   (Italy)

^f SINCROTRONE TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CYTOLOGY; DEFECTS; OPTIMIZATION; PLASMA (HUMAN); SCAFFOLDS (BIOLOGY); STEM CELLS;

BONE DEFECT; BONE DEVELOPMENT; BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; BONE MORPHOGENETIC PROTEIN-2; BONE REGENERATION; BONE REPAIR; GEL MEMBRANES; HUMAN ENDOTHELIAL CELLS; IN-VITRO; IN-VIVO; INTERLEUKIN-8; MOUSE MODELS; OPTIMAL RELEASE; OSTEOCONDUCTIVE SCAFFOLDS; OSTEOGENIC; OSTEOGENIC CAPACITY; OSTEOPROGENITOR CELLS; PDGF BB'S; PLATELET-RICH PLASMA; PROGENITOR CELL; SEGMENTAL BONE DEFECT; VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULARIZATION;

MEMBRANES;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

BIOMIMETIC MATERIAL;

ANGIOGENESIS; ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE PROSTHESIS; BONE REGENERATION; FRACTURE; HUMAN; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; METHODOLOGY; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PERIOSTEUM; PHYSIOLOGY; RABBIT; SYNTHESIS; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING; TREATMENT OUTCOME;

ANIMALS; BIOMIMETIC MATERIALS; BONE REGENERATION; BONE SUBSTITUTES; FRACTURES, BONE; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; PERIOSTEUM; PLATELET-RICH PLASMA; RABBITS; TISSUE ENGINEERING; TREATMENT OUTCOME;

EID: 84871689974     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0357     Document Type: Article

References (40)

1. Schmid, J., Wallkamm, B., Hammerle, C.H., Gogolewski, S., and Lang, N.P. The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment. Clin Oral Implants Res 8, 244, 1997.
2. Giannoni, P., Mastrogiacomo, M., Alini, M., Pearce, S.G., Corsi, A., Santolini, F., Muraglia, A., Bianco, P., and Cancedda, R. Regeneration of large bone defects in sheep using bone marrow stromal cells. J Tissue Eng Regen Med 2, 253, 2008.
3. Kannan, R.Y., Salacinski, H.J., Sales, K., Butler, P., and Seifalian, A.M. The roles of tissue engineering and vascularisation in the development of micro-vascular networks: A review. Biomaterials 26, 1857, 2005.
4. L'Heureux, N., Dusserre, N., Konig, G., Victor, B., Keire, P., Wight, T.N., Chronos, N.A., Kyles, A.E., Gregory, C.R., Hoyt, G., Robbins, R.C., and McAllister, T.N. Human tissueengineered blood vessels for adult arterial revascularization. Nat Med 12, 361, 2006.
5. Hofmann, A., Ritz, U., Verrier, S., Eglin, D., Alini, M., Fuchs, S., Kirkpatrick, C.J., and Rommens, P.M. The effect of human osteoblasts on proliferation and neo-vessel formation of human umbilical vein endothelial cells in a long-term 3D coculture on polyurethane scaffolds. Biomaterials 29, 4217, 2008.
6. Geiger, F., Bertram, H., Berger, I., Lorenz, H., Wall, O., Eckhardt, C., Simank, H.G., and Richter, W. Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res 20, 2028, 2005.
7. Gassling, V., Hedderich, J., Acil, Y., Purcz, N., Wiltfang, J., and Douglas, T. Comparison of platelet rich fibrin and collagen as osteoblast-seeded scaffolds for bone tissue engineering applications. Clin Oral Implants Res 2011 [Epub ahead of print]; Doi: 10.1111/j.1600-0501.2011.02333.x.
8. Guo, H., Li, X., Yuan, X., and Ma, X. Reconstruction of radial bone defects using the reinforced tissue-engineered periosteum: An experimental study on rabbit weight-bearing segment. J Trauma Acute Care Surg 72, E94, 2012.
9. Ma, D., Yao, H., Tian, W., Chen, F., Liu, Y., Mao, T., and Ren, L. Enhancing bone formation by transplantation of a scaffold-free tissue-engineered periosteum in a rabbit model. Clin Oral Implants Res 22, 1193, 2011.
10. Zhang, X., Awad, H.A., O'Keefe, R.J., Guldberg, R.E., and Schwarz, E.M. A perspective: Engineering periosteum for structural bone graft healing. Clin Orthop Relat Res 466, 1777, 2008.
11. Zhao, L., Zhao, J., Wang, S., Wang, J., and Liu, J. Comparative study between tissue-engineered periosteum and structural allograft in rabbit critical-sized radial defect model. J Biomed Mater Res B Appl Biomater 97, 1, 2011.
12. Colnot, C. Cell sources for bone tissue engineering: Insights from basic science. Tissue Eng Part B Rev 17, 449, 2011.
13. Kanczler, J.M., and Oreffo, R.O. Osteogenesis and angiogenesis: The potential for engineering bone. Eur Cell Mater 15, 100, 2008.
14. Maes, C., Kobayashi, T., Selig, M.K., Torrekens, S., Roth, S.I., Mackem, S., Carmeliet, G., and Kronenberg, H.M. Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell 19, 329, 2010.
15. Ozaki, A., Tsunoda, M., Kinoshita, S., and Saura, R. Role of fracture hematoma and periosteum during fracture healing in rats: Interaction of fracture hematoma and the periosteum in the initial step of the healing process. J Orthop Sci 5, 64, 2000.
16. Zhang, X., Xie, C., Lin, A.S., Ito, H., Awad, H., Lieberman, J.R., Rubery, P.T., Schwarz, E.M., O'Keefe, R.J., and Guldberg, R.E. Periosteal progenitor cell fate in segmental cortical bone graft transplantations: Implications for functional tissue engineering. J Bone Miner Res 20, 2124, 2005.
17. Mastrogiacomo, M., Papadimitropoulos, A., Cedola, A., Peyrin, F., Giannoni, P., Pearce, S.G., Alini, M., Giannini, C., Guagliardi, A., and Cancedda, R. Engineering of bone using bone marrow stromal cells and a silicon-stabilized tricalcium phosphate bioceramic: Evidence for a coupling between bone formation and scaffold resorption. Biomaterials 28, 1376, 2007.
18. Colnot, C. Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration. J Bone Miner Res 24, 274, 2009.
19. Hu, Z., Peel, S.A., Ho, S.K., Sandor, G.K., and Clokie, C.M. Platelet-rich plasma induces mRNA expression of VEGF and PDGF in rat bone marrow stromal cell differentiation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107, 43, 2009.
20. Arora, N.S., Ramanayake, T., Ren, Y.F., and Romanos, G.E. Platelet-rich plasma in sinus augmentation procedures: A systematic literature review: Part II. Implant Dent 19, 145, 2010.
21. Zaky, S.H., Ottonello, A., Strada, P., Cancedda, R., and Mastrogiacomo, M. Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineering. J Tissue Eng Regen Med 2, 472, 2008.
22. Martineau, I., Lacoste, E., and Gagnon, G. Effects of calcium and thrombin on growth factor release from platelet concentrates: Kinetics and regulation of endothelial cell proliferation. Biomaterials 25, 4489, 2004.
23. Laschke,M.W., Strohe, A., Menger,M.D., Alini,M., and Eglin, D. In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester- urethane) composite scaffold for bone tissue engineering. Acta Biomater 6, 2020, 2010.
24. Fan, W., Crawford, R., and Xiao, Y. Enhancing in vivo vascularized bone formation by cobalt chloride-treated bone marrow stromal cells in a tissue engineered periosteum model. Biomaterials 31, 3580, 2010.
25. Okuda, K., Yamamiya, K., Kawase, T., Mizuno, H., Ueda, M., and Yoshie, H. Treatment of human infrabony periodontal defects by grafting human cultured periosteum sheets combined with platelet-rich plasma and porous hydroxyapatite granules: Case series. J Int Acad Periodontol 11, 206, 2009.
26. Yamamiya, K., Okuda, K., Kawase, T., Hata, K., Wolff, L.F., and Yoshie, H. Tissue-engineered cultured periosteum used with platelet-rich plasma and hydroxyapatite in treating human osseous defects. J Periodontol 79, 811, 2008.
27. Zhou, Y., Chen, F., Ho, S.T., Woodruff, M.A., Lim, T.M., and Hutmacher, D.W. Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts. Biomaterials 28, 814, 2007.
28. Schonmeyr, B., Clavin, N., Avraham, T., Longo, V., and Mehrara, B.J. Synthesis of a tissue-engineered periosteum with acellular dermal matrix and cultured mesenchymal stem cells. Tissue Eng Part A 15, 1833, 2009.
29. El Backly, R., Ulivi, V., Tonachini, L., Cancedda, R., Descalzi, F., and Mastrogiacomo, M. Platelet lysate induces in vitro wound healing of human keratinocytes associated with a strong proinflammatory response. Tissue Eng Part A 17, 1787, 2011.
30. Sahni, A., and Francis, C.W. Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation. Blood 96, 3772, 2000.
31. Verrier, S., Meury, T.R., Kupcsik, L., Heini, P., Stoll, T., and Alini, M. Platelet-released supernatant induces osteoblastic differentiation of human mesenchymal stem cells: Potential role of BMP-2. Eur Cell Mater 20, 403, 2010.
32. Rawadi, G., Vayssiere, B., Dunn, F., Baron, R., and Roman-Roman, S. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res 18, 1842, 2003.
33. Karsenty, G. Minireview: Transcriptional control of osteoblast differentiation. Endocrinology 142, 2731, 2001.
34. Lian, J.B., and Stein, G.S. Development of the osteoblast phenotype: Molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop J 15, 118, 1995.
35. Gruber, R., Karreth, F., Kandler, B., Fuerst, G., Rot, A., Fischer, M.B., and Watzek, G. Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets 15, 29, 2004.
36. Osyczka, A.M., Diefenderfer, D.L., Bhargave, G., and Leboy, P.S. Different effects of BMP-2 on marrow stromal cells from human and rat bone. Cells Tissues Organs 176, 109, 2004.
37. Bir, S.C., Esaki, J., Marui, A., Sakaguchi, H., Kevil, C.G., Ikeda, T., Komeda, M., Tabata, Y., and Sakata, R. Therapeutic treatment with sustained-release platelet-rich plasma restores blood perfusion by augmenting ischemiainduced angiogenesis and arteriogenesis in diabetic mice. J Vasc Res 48, 195, 2011.
38. Cenni, E., Ciapetti, G., Granchi, D., Fotia, C., Perut, F., Giunti, A., and Baldini, N. Endothelial cells incubated with platelet-rich plasma express PDGF-B and ICAM-1 and induce bone marrow stromal cell migration. J Orthop Res 27, 493, 2009.
39. Caplan, A.I., and Correa, D. The MSC: An injury drugstore. Cell Stem Cell 9, 11, 2011.
40. Yu, Y.Y., Lieu, S., Lu, C., and Colnot, C. Bone morphogenetic protein 2 stimulates endochondral ossification by regulating periosteal cell fate during bone repair. Bone 47, 65, 2010.