Enhancement of solubility, antioxidant ability and bioavailability of taxifolin nanoparticles by liquid antisolvent precipitation technique

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 366-376

  Zu, Yuangang ^a   Wu, Weiwei ^a   Zhao, Xiuhua ^a   Li, Yong ^a   Wang, Weiguo ^a   Zhong, Chen ^a   Zhang, Yin ^a   Zhao, Xue ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

Author keywords

Antioxidant ability; Bioavailability; Dissolution rate; LAP; Nanoparticles; Taxifolin

Indexed keywords

ALCOHOL; GAMMA CYCLODEXTRIN; GLUCOSE; LACTOSE; MANNITOL; NANOPARTICLE; POLOXAMER; TAXIFOLIN; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ANTIOXIDANT; BIPHENYL DERIVATIVE; DRUG CARRIER; PICRIC ACID; QUERCETIN; SOLVENT; WATER;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG SOLUBILITY; DRUG SYNTHESIS; FEMALE; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; IN VIVO STUDY; INFRARED SPECTROSCOPY; LIQUID ANTISOLVENT PRECIPITATION; MASS SPECTROMETRY; NONHUMAN; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TEMPERATURE; THERMOGRAVIMETRY; X RAY DIFFRACTION; ANALOGS AND DERIVATIVES; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DRUG FORMULATION; PROCEDURES; SOLUBILITY; SPRAGUE DAWLEY RAT; SURFACE PROPERTY; TISSUE DISTRIBUTION;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL AVAILABILITY; BIPHENYL COMPOUNDS; CHEMICAL PRECIPITATION; DRUG CARRIERS; DRUG COMPOUNDING; ETHANOL; FEMALE; NANOPARTICLES; PARTICLE SIZE; PICRATES; QUERCETIN; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOLVENTS; SURFACE PROPERTIES; TISSUE DISTRIBUTION; WATER;

EID: 84902186150     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.049     Document Type: Article

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