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Volumn 18, Issue 7, 2014, Pages 959-964

Effects of fasudil on hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats

Author keywords

Fasudil; Pulmonary arterial hypertension (PAH); Pulmonary vascular remodeling

Indexed keywords

COLLAGEN FIBER; FASUDIL; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; PROTEIN KINASE INHIBITOR; RHO KINASE;

EID: 84902185458     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (23)

References (22)
  • 3
    • 79961067803 scopus 로고    scopus 로고
    • Rho-kinase: Important new therapeutic target in cardiovascular diseases
    • SATOH K, FUKUMOTO Y, SHIMOKAWA H. Rho-kinase: important new therapeutic target in cardiovascular diseases. Am J Physiol Heart Circ Physiol 2011; 301: H287-H296.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Satoh, K.1    Fukumoto, Y.2    Shimokawa, H.3
  • 4
    • 80052191711 scopus 로고    scopus 로고
    • Pulmonary hypertension: Current therapy and future prospects
    • MATHEW R. Pulmonary hypertension: current therapy and future prospects. Cardiovasc Hematol Agents Med Chem 2011; 9: 165-182.
    • (2011) Cardiovasc Hematol Agents Med Chem , vol.9 , pp. 165-182
    • Mathew, R.1
  • 6
    • 84863551553 scopus 로고    scopus 로고
    • Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension
    • RAJA SG. Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension. Recent Pat Cardiovasc Drug Discov 2012; 7: 100-104.
    • (2012) Recent Pat Cardiovasc Drug Discov , vol.7 , pp. 100-104
    • Raja, S.G.1
  • 7
    • 79952281574 scopus 로고    scopus 로고
    • The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension
    • SAKAO S, TATSUMI K. The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension. Respiration 2011; 81: 253-261.
    • (2011) Respiration , vol.81 , pp. 253-261
    • Sakao, S.1    Tatsumi, K.2
  • 9
    • 42649085057 scopus 로고    scopus 로고
    • Changes and distributions of peptides derived from proadrenomedullin in left-to-right shunt pulmonary hypertension of rats
    • DOI 10.1253/circj.72.476
    • CUIFEN Z, LIJUAN W, LI G., WEI X, ZHIYU W, FUHAI L. Changes and distributions of peptides derived from proadrenomedullin in left-to-right shunt pulmonary hypertension of rats. Circ J 2008; 72: 476-481. (Pubitemid 351600646)
    • (2008) Circulation Journal , vol.72 , Issue.3 , pp. 476-481
    • Cuifen, Z.1    Lijuan, W.2    Li, G.3    Wei, X.4    Zhiyu, W.5    Fuhai, L.6
  • 10
    • 78649759302 scopus 로고    scopus 로고
    • Rescue treatment with a rho-kinase inhibitor Normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension
    • XU EZ, KANTORES C, IVANOVSKA J., ENGELBERTS D, KAVANAGH B P, MCNAMARA PJ, JANKOV RP. Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension. Am J Physiol Heart Circ Physiol 2010; 299: H1854-H1864.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Xu, E.Z.1    Kantores, C.2    Ivanovska, J.3    Engelberts, D.4    Kavanagh, B.P.5    McNamara, P.J.6    Jankov, R.P.7
  • 11
    • 0036875930 scopus 로고    scopus 로고
    • Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension
    • DOI 10.1053/pcad.2002.130041
    • JEFFERY TK, MORRELL NW Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension. Prog Cardiovasc Dis 2002; 45: 173-202. (Pubitemid 36139815)
    • (2002) Progress in Cardiovascular Diseases , vol.45 , Issue.3 , pp. 173-202
    • Jeffery, T.K.1    Morrell, N.W.2
  • 12
    • 1642453778 scopus 로고    scopus 로고
    • Endothelial Dysfunction in Pulmonary Hypertension
    • DOI 10.1161/01.CIR.0000102381.57477.50
    • BUDHIRAJA R, TUDER RM, HASSOUN PM Endothelial dysfunction in pulmonary hypertension. Circulation 2004; 109: 159-165. (Pubitemid 38114133)
    • (2004) Circulation , vol.109 , Issue.2 , pp. 159-165
    • Budhiraja, R.1    Tuder, R.M.2    Hassoun, P.M.3
  • 13
    • 22744457972 scopus 로고    scopus 로고
    • Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: A time for reappraisal?
    • DOI 10.1161/01.RES.00000175934.68087.29
    • STENMARK KR, MCMURTRY IF Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: A time for reappraisal? Circ Res 2005; 97: 95-98. (Pubitemid 41033463)
    • (2005) Circulation Research , vol.97 , Issue.2 , pp. 95-98
    • Stenmark, K.R.1    McMurtry, I.F.2
  • 14
    • 0036092602 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide
    • EARLEY S, NELIN LD, CHICOINE L.G., WALKER BR Hy-poxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide. J Appl Physiol 2002; 92: 1152-1158. (Pubitemid 34670974)
    • (2002) Journal of Applied Physiology , vol.92 , Issue.3 , pp. 1152-1158
    • Earley, S.1    Nelin, L.D.2    Chicoine, L.G.3    Walker, B.R.4
  • 16
    • 79960792540 scopus 로고    scopus 로고
    • Recent progress in the management of pulmonary hypertension
    • FUKUMOTO Y, SHIMOKAWA H. Recent progress in the management of pulmonary hypertension. Circ J 2011; 75: 1801-1810.
    • (2011) Circ J , vol.75 , pp. 1801-1810
    • Fukumoto, Y.1    Shimokawa, H.2
  • 17
    • 79953686516 scopus 로고    scopus 로고
    • New perspectives for the treatment of pulmonary hypertension
    • BALIGA RS, MACALLISTER RJ, HOBBS AJ New perspectives for the treatment of pulmonary hypertension. Br J Pharmacol 2011; 163: 125-140.
    • (2011) Br J Pharmacol , vol.163 , pp. 125-140
    • Baliga, R.S.1    Macallister, R.J.2    Hobbs, A.J.3
  • 18
    • 84859607472 scopus 로고    scopus 로고
    • Targeting RhoA/ROCK pathway in pulmonary arterial hypertension
    • ANTONIU SA. Targeting RhoA/ROCK pathway in pulmonary arterial hypertension. Expert Opin Ther Targets 2012; 16: 355-363.
    • (2012) Expert Opin Ther Targets , vol.16 , pp. 355-363
    • Antoniu, S.A.1
  • 19
    • 84922685388 scopus 로고    scopus 로고
    • Development of rho kinase inhibitors for pulmonary arterial hypertension
    • SETO M. Development of Rho kinase inhibitors for pulmonary arterial hypertension. Nihon Yakuri-gaku Zasshi 2012; 139: 251-255.
    • (2012) Nihon Yakuri-gaku Zasshi , vol.139 , pp. 251-255
    • Seto, M.1
  • 20
    • 70350724182 scopus 로고    scopus 로고
    • RhoA/Rho-kinase signaling: A therapeutic target in pulmonary hypertension
    • BARMAN SA, ZHU S, WHITE RE RhoA/Rho-kinase signaling: A therapeutic target in pulmonary hypertension. Vasc Health Risk Manag 2009; 5: 663-671.
    • (2009) Vasc Health Risk Manag , vol.5 , pp. 663-671
    • Barman, S.A.1    Zhu, S.2    White, R.E.3
  • 22
    • 77950921360 scopus 로고    scopus 로고
    • Acute vasodilator effects of inhaled fasudil, a specific rho-kinase inhibitor, in patients with pulmonary arterial hypertension
    • FUJITA H, FUKUMOTO Y, SAJI K., SUGIMURA K, DEMACHI J, NAWATA J., SHIMOKAWA H. Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension. Heart Vessels 2010; 25: 144-149.
    • (2010) Heart Vessels , vol.25 , pp. 144-149
    • Fujita, H.1    Fukumoto, Y.2    Saji, K.3    Sugimura, K.4    Demachi, J.5    Nawata, J.6    Shimokawa, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.