Nerve conduits for peripheral nerve surgery

Plastic and Reconstructive Surgery

Volumn 133, Issue 6, 2014, Pages 1420-1430

  Pabari, Amit ^a,b   Lloyd Hughes, Hawys ^b   Seifalian, Alexander M ^b   Mosahebi, Ash ^b  

^a ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL PEPTIDE; TISSUE SCAFFOLD;

ARTICLE; HUMAN; METHODOLOGY; NERVE REGENERATION; PERIPHERAL NERVE; PERIPHERAL NERVE INJURY; TISSUE ENGINEERING;

HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE REGENERATION; PERIPHERAL NERVE INJURIES; PERIPHERAL NERVES; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84902177382     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0000000000000226     Document Type: Article

References (105)

1. Schlosshauer B, Dreesmann L, Schaller HE, Sinis N.Synthetic nerve guide implants in humans: A comprehensivesurvey. Neurosurgery 2006;59:740-747; discussion 747.
2. Deal DN, Griffin JW, Hogan MV. Nerve conduits for nerverepair or reconstruction. J Am Acad Orthop Surg. 2012;20:63-68.
3. Millesi H. Nerve grafting. Clin Plast Surg. 1984;11:105-113.
4. Siemionow M, Brzezicki G. Chapter 8: Current techniquesand concepts in peripheral nerve repair. Int Rev Neurobiol. 2009;87:141-172.
5. Panseri S, Cunha C, Lowery J, et al. Electrospun micro-andnanofiber tubes for functional nervous regeneration in sciaticnerve transections. BMC Biotechnol. 2008;8:39.
6. Kehoe S, Zhang XF, Boyd D. FDA approved guidance conduitsand wraps for peripheral nerve injury: A review ofmaterials and efficacy. Injury 2012;43:553-572.
7. Lohmeyer JA, Siemers F, Machens HG, Mailänder P. Theclinical use of artificial nerve conduits for digital nerverepair: A prospective cohort study and literature review.J Reconstr Microsurg. 2009;25:55-61.
8. Bertleff MJ, Meek MF, Nicolai JP. A prospective clinical evaluationof biodegradable neurolac nerve guides for sensorynerve repair in the hand. J Hand Surg Am. 2005;30:513-518.
9. Bushnell BD, McWilliams AD, Whitener GB, Messer TM.Early clinical experience with collagen nerve tubes in digitalnerve repair. J Hand Surg Am. 2008;33:1081-1087.
10. Rosson GD, Williams EH, Dellon AL. Motor nerve regenerationacross a conduit. Microsurgery 2009;29:107-114.
11. Smith RM, Wiedl C, Chubb P, Greene CH. Role of smallintestine submucosa (SIS) as a nerve conduit: Preliminaryreport. J Invest Surg. 2004;17:339-344.
12. Merle M, Dellon AL, Campbell JN, Chang PS. Complicationsfrom silicon-polymer intubulation of nerves. Microsurgery1989;10:130-133.
13. Meek MF, Coert JH. Clinical use of nerve conduits inperipheral-nerve repair: Review of the literature. J ReconstrMicrosurg. 2002;18:97-109.
14. Taras JS, Nanavati V, Steelman P. Nerve conduits. J HandTher. 2005;18:191-197.
15. Mackinnon SE, Dellon AL. Clinical nerve reconstructionwith a bioabsorbable polyglycolic acid tube. Plast ReconstrSurg. 1990;85:419-424.
16. Weber RA, Breidenbach WC, Brown RE, Jabaley ME, MassDP. A randomized prospective study of polyglycolic acidconduits for digital nerve reconstruction in humans. PlastReconstr Surg. 2000;106:1036-1045; discussion 1046.
17. Meek MF, Coert JH. US Food and Drug Administration/Conformit Europe-approved absorbable nerve conduits forclinical repair of peripheral and cranial nerves. Ann PlastSurg. 2008;60:466-472.
18. Wolford LM, Stevao EL. Considerations in nerve repair. Proc(Bayl Univ Med Cent.) 2003;16:152-156.
19. Waitayawinyu T, Parisi DM, Miller B, et al. A comparison ofpolyglycolic acid versus type 1 collagen bioabsorbable nerveconduits in a rat model: An alternative to autografting.J Hand Surg Am. 2007;32:1521-1529.
20. Hadlock TA, Sundback CA, Hunter DA, Vacanti JP, CheneyML. A new artificial nerve graft containing rolled Schwanncell monolayers. Microsurgery 2001;21:96-101.
21. Kokkalis ZT, Pu C, Small GA, Weiser RW, Venouziou AI,Sotereanos DG. Assessment of processed porcine extracellularmatrix as a protective barrier in a rabbit nerve wrapmodel. J Reconstr Microsurg. 2011;27:19-28.
22. Stang F, Fansa H, Wolf G, Keilhoff G. Collagen nerve conduits:Assessment of biocompatibility and axonal regeneration.Biomed Mater Eng. 2005;15:3-12.
23. Keilhoff G, Stang F, Wolf G, Fansa H. Bio-compatibility oftype I/III collagen matrix for peripheral nerve reconstruction.Biomaterials 2003;24:2779-2787.
24. Farole A, Jamal BT. A bioabsorbable collagen nerve cuff(NeuraGen) for repair of lingual and inferior alveolarnerve injuries: A case series. J Oral Maxillofac Surg. 2008;66:2058-2062.
25. Whitlock EL, Tuffaha SH, Luciano JP, et al. Processedallografts and type I collagen conduits for repair of peripheralnerve gaps. Muscle Nerve 2009;39:787-799.
26. Kim DH, Connolly SE, Zhao S, Beuerman RW, Voorhies RM,Kline DG. Comparison of macropore, semipermeable, andnonpermeable collagen conduits in nerve repair. J ReconstrMicrosurg. 1993;9:415-420.
27. Luis AL, Rodrigues JM, Lobato JV, et al. Evaluation of twobiodegradable nerve guides for the reconstruction of the ratsciatic nerve. Biomed Mater Eng. 2007;17:39-52.
28. Shin RH, Friedrich PF, Crum BA, Bishop AT, Shin AY.Treatment of a segmental nerve defect in the rat with useof bioabsorbable synthetic nerve conduits: A comparisonof commercially available conduits. J Bone Joint Surg Am. 2009;91:2194-2204.
29. Meek MF, Jansen K. Two years after in vivo implantation ofpoly(DL-lactide-epsilon-caprolactone) nerve guides: Has thematerial finally resorbed J Biomed Mater Res A 2009;89:734-738.
30. Brooks DN, Weber RV, Chao JD, et al. Processed nerveallografts for peripheral nerve reconstruction: A multicenterstudy of utilization and outcomes in sensory, mixed, andmotor nerve reconstructions. Microsurgery 2012;32:1-14.
31. Bian YZ, Wang Y, Aibaidoula G, Chen GQ, Wu Q. Evaluationof poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) conduitsfor peripheral nerve regeneration. Biomaterials2009;30:217-225.
32. Reid AJ, de Luca AC, Faroni A, et al. Long term peripheralnerve regeneration using a novel PCL nerve conduit.Neurosci Lett. 2013;544:125-130.
33. Smahel J, Meyer VE, Bachem U. Glueing of peripheralnerves with fibrin: Experimental studies. J Reconstr Microsurg. 1987;3:211-220.
34. Martins RS, Siqueira MG, Da Silva CF, Plese JP. Overallassessment of regeneration in peripheral nerve lesion repairusing fibrin glue, suture, or a combination of the 2 techniquesin a rat model: Which is the ideal choice Surg Neurol. 2005;64(Suppl 1):S1:10-16; discussion S1:16.
35. Ornelas L, Padilla L, Di Silvio M, et al. Fibrin glue: Analternative technique for nerve coaptation-Part I. Waveamplitude, conduction velocity, and plantar-length factors.J Reconstr Microsurg. 2006;22:119-122.
36. Ornelas L, Padilla L, Di Silvio M, et al. Fibrin glue: Analternative technique for nerve coaptation-Part II. Nerveregeneration and histomorphometric assessment. J ReconstrMicrosurg. 2006;22:123-128.
37. Bozorg Grayeli A, Mosnier I, Julien N, El Garem H, BouccaraD, Sterkers O. Long-term functional outcome in facial nervegraft by fibrin glue in the temporal bone and cerebellopontineangle. Eur Arch Otorhinolaryngol. 2005;262:404-407.
38. Sameem M, Wood TJ, Bain JR. A systematic review on the useof fibrin glue for peripheral nerve repair. Plast Reconstr Surg. 2011;127:2381-2390.
39. Chaudhry V, Glass JD, Griffin JW. Wallerian degeneration inperipheral nerve disease. Neurol Clin. 1992;10:613-627.
40. Fenrich K, Gordon T. Canadian Association of Neurosciencereview: Axonal regeneration in the peripheral and centralnervous systems. Current issues and advances. Can J NeurolSci. 2004;31:142-156.
41. Fu SY, Gordon T. The cellular and molecular basis of peripheralnerve regeneration. Mol Neurobiol. 1997;14:67-116.
42. Belkas JS, Shoichet MS, Midha R. Peripheral nerve regenerationthrough guidance tubes. Neurol Res. 2004;26:151-160.
43. Evans GR. Peripheral nerve injury: A review and approach totissue engineered constructs. Anat Rec. 2001;263:396-404.
44. Moore AM, Kasukurthi R, Magill CK, Farhadi HF, BorschelGH, Mackinnon SE. Limitations of conduits in peripheralnerve repairs. Hand (NY) 2009;4:180-186.
45. Jenq CB, Coggeshall RE. Nerve regeneration through holeysilicone tubes. Brain Res. 1985;361:233-241.
46. Aebischer P, Guénard V, Valentini RF. The morphology ofregenerating peripheral nerves is modulated by the surfacemicrogeometry of polymeric guidance channels. Brain Res. 1990;531:211-218.
47. Dellon AL, Mackinnon SE. An alternative to the classicalnerve graft for the management of the short nerve gap. PlastReconstr Surg. 1988;82:849-856.
48. Rodríguez FJ, Gómez N, Perego G, Navarro X. Highly permeablepolylactide-caprolactone nerve guides enhance peripheralnerve regeneration through long gaps. Biomaterials1999;20:1489-1500.
49. Widmer MS, Gupta PK, Lu L, et al. Manufacture ofporous biodegradable polymer conduits by an extrusionprocess for guided tissue regeneration. Biomaterials1998;19:1945-1955.
50. Wang A, Ao Q, Wei Y, et al. Physical properties and biocompatibilityof a porous chitosan-based fiber-reinforced conduitfor nerve regeneration. Biotechnol Lett. 2007;29:1697-1702.
51. Belkas JS, Munro CA, Shoichet MS, Johnston M, Midha R.Long-term in vivo biomechanical properties and biocompatibilityof poly(2-hydroxyethyl methacrylate-co-methyl methacrylate)nerve conduits. Biomaterials 2005;26:1741-1749.
52. Meek MF, Jansen K, Steendam R, van Oeveren W, vanWachem PB, van Luyn MJ. In vitro degradation and biocompatibilityof poly(DL-lactide-epsilon- caprolactone) nerveguides. J Biomed Mater Res A 2004;68:43-51.
53. Uebersax L, Mattotti M, Papaloïzos M, Merkle HP, Gander B,Meinel L. Silk fibroin matrices for the controlled release ofnerve growth factor (NGF). Biomaterials 2007;28:4449-4460.
54. Wang S, Cai L. Polymers for fabricating nerve conduits. Int JPolym Sci. 2010.
55. Chew SY, Mi R, Hoke A, Leong KW. Aligned protein-polymercomposite fibers enhance nerve regeneration: A potential tissue-engineering platform. Adv Funct Mater. 2007;17:1288-1296.
56. Bozkurt A, Deumens R, Beckmann C, et al. In vitro cellalignment obtained with a Schwann cell enriched microstructurednerve guide with longitudinal guidance channels.Biomaterials 2009;30:169-179.
57. Hisasue S, Kato R, Sato Y, Suetomi T, Tabata Y, TsukamotoT. Cavernous nerve reconstruction with a biodegradableconduit graft and collagen sponge in the rat. J Urol. 2005;173:286-291.
58. Yu TT, Shoichet MS. Guided cell adhesion and outgrowthin peptide-modified channels for neural tissue engineering.Biomaterials 2005;26:1507-1514.
59. Nakamura T, Inada Y, Fukuda S, et al. Experimental studyon the regeneration of peripheral nerve gaps through apolyglycolic acid-collagen (PGA-collagen) tube. Brain Res. 2004;1027:18-29.
60. Hadlock T, Sundback C, Hunter D, Cheney M, Vacanti JP.A polymer foam conduit seeded with Schwann cells promotesguided peripheral nerve regeneration. Tissue Eng. 2000;6:119-127.
61. Ansselin AD, Fink T, Davey DF. Peripheral nerve regenerationthrough nerve guides seeded with adult Schwann cells.Neuropathol Appl Neurobiol. 1997;23:387-398.
62. Evans GR, Brandt K, Katz S, et al. Bioactive poly(L-lacticacid) conduits seeded with Schwann cells for peripheralnerve regeneration. Biomaterials 2002;23:841-848.
63. Sinis N, Schaller HE, Schulte-Eversum C, et al. Nerveregeneration across a 2-cm gap in the rat median nerveusing a resorbable nerve conduit filled with Schwann cells.J Neurosurg. 2005;103:1067-1076.
64. Pfister BJ, Iwata A, Taylor AG, Wolf JA, Meaney DF, SmithDH. Development of transplantable nervous tissue constructscomprised of stretch-grown axons. J Neurosci Methods2006;153:95-103.
65. Zhang Y, Ouyang H, Lim CT, Ramakrishna S, Huang ZM.Electrospinning of gelatin fibers and gelatin/PCL compositefibrous scaffolds. J Biomed Mater Res B Appl Biomater. 2005;72:156-165.
66. Nie X, Zhang YJ, Tian WD, et al. Improvement of peripheralnerve regeneration by a tissue-engineered nerve filledwith ectomesenchymal stem cells. Int J Oral Maxillofac Surg. 2007;36:32-38.
67. Phillips JB, Bunting SC, Hall SM, Brown RA. Neural tissueengineering: A self-organizing collagen guidance conduit.Tissue Eng. 2005;11:1611-1617.
68. You H, Wei L, Liu Y, et al. Olfactory ensheathing cellsenhance Schwann cell-mediated anatomical and functionalrepair after sciatic nerve injury in adult rats. Exp Neurol. 2011;229:158-167.
69. Udina E, Rodríguez FJ, Verdú E, Espejo M, Gold BG,Navarro X. FK506 enhances regeneration of axonsacross long peripheral nerve gaps repaired with collagenguides seeded with allogeneic Schwann cells. Glia2004;47:120-129.
70. Apel PJ, Garrett JP, Sierpinski P, et al. Peripheral nerveregeneration using a keratin-based scaffold: Long-term functionaland histological outcomes in a mouse model. J HandSurg Am. 2008;33:1541-1547.
71. Kalbermatten DF, Erba P, Mahay D, Wiberg M, Pierer G,Terenghi G. Schwann cell strip for peripheral nerve repair.J Hand Surg Eur Vol. 2008;33:587-594.
72. di Summa PG, Kingham PJ, Raffoul W, Wiberg M, TerenghiG, Kalbermatten DF. Adipose-derived stem cells enhanceperipheral nerve regeneration. J Plast Reconstr Aesthet Surg. 2010;63:1544-1552.
73. Ruitenberg MJ, Vukovic J, Sarich J, Busfield SJ, PlantGW. Olfactory ensheathing cells: Characteristics, geneticengineering, and therapeutic potential. J Neurotrauma2006;23:468-478.
74. Byrnes KR, Wu X, Waynant RW, Ilev IK, Anders JJ. Lowpower laser irradiation alters gene expression of olfactoryensheathing cells in vitro. Lasers Surg Med. 2005;37:161-171.
75. Akiyama Y, Lankford K, Radtke C, Greer CA, Kocsis JD.Remyelination of spinal cord axons by olfactory ensheathingcells and Schwann cells derived from a transgenic ratexpressing alkaline phosphatase marker gene. Neuron GliaBiol. 2004;1:47-55.
76. Pabari A, Yang SY, Seifalian AM, Mosahebi A. Modern surgicalmanagement of peripheral nerve gap. J Plast ReconstrAesthet Surg. 2010;63:1941-1948.
77. Amoh Y, Kanoh M, Niiyama S, et al. Human hair folliclepluripotent stem (hfPS) cells promote regeneration ofperipheral-nerve injury: An advantageous alternative to ESand iPS cells. J Cell Biochem. 2009;107:1016-1020.
78. Keilhoff G, Goihl A, Langnäse K, Fansa H, Wolf G. Transdifferentiation of mesenchymal stem cells into Schwanncell-like myelinating cells. Eur J Cell Biol. 2006;85:11-24.
79. Caddick J, Kingham PJ, Gardiner NJ, Wiberg M, Terenghi G.Phenotypic and functional characteristics of mesenchymalstem cells differentiated along a Schwann cell lineage. Glia2006;54:840-849.
80. Wang J, Ding F, Gu Y, Liu J, Gu X. Bone marrow mesenchymalstem cells promote cell proliferation and neurotrophic functionof Schwann cells in vitro and in vivo. Brain Res. 2009;1262:7-15.
81. Tohill M, Mantovani C, Wiberg M, Terenghi G. Rat bone marrowmesenchymal stem cells express glial markers and stimulatenerve regeneration. Neurosci Lett. 2004;362:200-203.
82. Ribeiro-Resende VT, Carrier-Ruiz A, Lemes RM, Reis RA,Mendez-Otero R. Bone marrow-derived fibroblast growthfactor-2 induces glial cell proliferation in the regeneratingperipheral nervous system. Mol Neurodegener. 2012;7:34.
83. Raivich G, Kreutzberg GW. Peripheral nerve regeneration:Role of growth factors and their receptors. Int J Dev Neurosci. 1993;11:311-324.
84. Pfister LA, Papaloïzos M, Merkle HP, Gander B. Nerve conduitsand growth factor delivery in peripheral nerve repair.J Peripher Nerv Syst. 2007;12:65-82.
85. Madduri S, Feldman K, Tervoort T, Papaloïzos M, Gander B.Collagen nerve conduits releasing the neurotrophic factorsGDNF and NGF. J Control Release 2010;143:168-174.
86. Midha R, Munro CA, Dalton PD, Tator CH, Shoichet MS.Growth factor enhancement of peripheral nerve regenerationthrough a novel synthetic hydrogel tube. J Neurosurg. 2003;99:555-565.
87. Vögelin E, Baker JM, Gates J, Dixit V, Constantinescu MA,Jones NF. Effects of local continuous release of brain derivedneurotrophic factor (BDNF) on peripheral nerve regenerationin a rat model. Exp Neurol. 2006;199:348-353.
88. Ho PR, Coan GM, Cheng ET, et al. Repair with collagentubules linked with brain-derived neurotrophic factor andciliary neurotrophic factor in a rat sciatic nerve injury model.Arch Otolaryngol Head Neck Surg. 1998;124:761-766.
89. Goraltchouk A, Scanga V, Morshead CM, Shoichet MS.Incorporation of protein-eluting microspheres into biodegradablenerve guidance channels for controlled release.J Control Release 2006;110:400-407.
90. Ohta M, Suzuki Y, Chou H, et al. Novel heparin/alginategel combined with basic fibroblast growth factor promotesnerve regeneration in rat sciatic nerve. J Biomed Mater Res A2004;71:661-668.
91. Zhou L, Du HD, Tian HB, Li C, Tian J, Jiang JJ. Experimentalstudy on repair of the facial nerve with Schwann cells transfectedwith GDNF genes and PLGA conduits. Acta Otolaryngol. 2008;128:1266-1272.
92. Mohanna PN, Terenghi G, Wiberg M. Composite PHB-GGFconduit for long nerve gap repair: A long-term evaluation.Scand J Plast Reconstr Surg Hand Surg. 2005;39:129-137.
93. Fansa H, Schneider W, Wolf G, Keilhoff G. Influence ofinsulin-like growth factor-I (IGF-I) on nerve autografts andtissue-engineered nerve grafts. Muscle Nerve 2002;26:87-93.
94. McKay Hart A, Wiberg M, Terenghi G. Exogenous leukaemiainhibitory factor enhances nerve regeneration after latesecondary repair using a bioartificial nerve conduit. Br J PlastSurg. 2003;56:444-450.
95. Kemp SW, Walsh SK, Zochodne DW, Midha R. A novelmethod for establishing daily in vivo concentration gradientsof soluble nerve growth factor (NGF). J Neurosci Methods2007;165:83-88.
96. Dodla MC, Bellamkonda RV. Differences between the effectof anisotropic and isotropic laminin and nerve growth factorpresenting scaffolds on nerve regeneration across longperipheral nerve gaps. Biomaterials 2008;29:33-46.
97. Wells MR, Kraus K, Batter DK, et al. Gel matrix vehiclesfor growth factor application in nerve gap injuries repairedwith tubes: A comparison of biomatrix, collagen, and methylcellulose.Exp Neurol. 1997;146:395-402.
98. Hobson MI. Increased vascularisation enhances axonalregeneration within an acellular nerve conduit. Ann R CollSurg Engl. 2002;84:47-53.
99. Aebischer P, Valentini RF, Dario P, Domenici C, Galletti PM.Piezoelectric guidance channels enhance regeneration in themouse sciatic nerve after axotomy. Brain Res. 1987;436:165-168.
100. Schmidt CE, Shastri VR, Vacanti JP, Langer R. Stimulation ofneurite outgrowth using an electrically conducting polymer.Proc Natl Acad Sci USA 1997;94:8948-8953.
101. de Ruiter GC, Malessy MJ, Yaszemski MJ, Windebank AJ,Spinner RJ. Designing ideal conduits for peripheral nerverepair. Neurosurg Focus 2009;26:E5.
102. Al-Majed AA, Neumann CM, Brushart TM, Gordon T. Briefelectrical stimulation promotes the speed and accuracy ofmotor axonal regeneration. J Neurosci. 2000;20:2602-2608.
103. Huang J, Lu L, Zhang J, et al. Electrical stimulation to conductivescaffold promotes axonal regeneration and remyelinationin a rat model of large nerve defect. PLoS One2012;7:e39526.
104. Krarup C, Archibald SJ, Madison RD. Factors that influenceperipheral nerve regeneration: An electrophysiologicalstudy of the monkey median nerve. Ann Neurol. 2002;51:69-81.
105. Brenner MJ, Moradzadeh A, Myckatyn TM, et al. Role oftiming in assessment of nerve regeneration. Microsurgery2008;28:265-272.