Do lipids show state-dependent affinity to the voltage-gated potassium channel kvap?

Journal of Biological Chemistry

Volumn 289, Issue 23, 2014, Pages 16452-16461

  Faure, Élise ^a   Thompson, Christine ^a   Blunck, Rikard ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; LIPID BILAYERS; MOLECULAR BIOLOGY; PURIFICATION;

CHANNEL BEHAVIOR; ELECTROSTATIC CHARGES; GATING MECHANISMS; INTEGRAL MEMBRANE PROTEINS; LIPID COMPOSITION; PHYSICOCHEMICAL PROPERTY; VOLTAGE GATED ION CHANNELS; VOLTAGE-GATED POTASSIUM CHANNELS;

LIPIDS;

LIPID; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL KVAP;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHANNEL GATING; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; LIPID BILAYER; LIPID COMPOSITION; NONHUMAN; POTASSIUM CONDUCTANCE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PURIFICATION; SIGNAL TRANSDUCTION; STATIC ELECTRICITY;

DOTAP; ELECTROPHYSIOLOGY; GATING; ION CHANNEL; LIPID REGULATION; MEMBRANE RECONSTITUTION; POTASSIUM CHANNEL; VOLTAGE-GATED POTASSIUM CHANNEL;

ION CHANNEL GATING; LIPID METABOLISM; POTASSIUM CHANNELS;

EID: 84902175918     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.537134     Document Type: Article

References (40)

1. + channel. Science 309, 897-903
2. + channel in a lipid membrane-like environment. Nature 450, 376-382
3. Blunck, R., and Batulan, Z. (2012) Mechanism of electromechanical coupling in voltage-gated potassium channels. Front. Pharmacol. 3, 166
4. Schmidt, D., Jiang, Q. X., and MacKinnon, R. (2006) Phospholipids and the origin of cationic gating charges in voltage sensors. Nature 444, 775-779
5. Börjesson, S. I., Hammarström, S., and Elinder, F. (2008) Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids. Biophys. J. 95, 2242-2253
6. + channel in transmembrane signaling. J. Immunol. 166, 1009-1015
7. Faure, é., Starek, G., McGuire, H., Bernèche, S., and Blunck, R. (2012) A limited 4-Å radial displacement of the S4-S5 linker is sufficient for internal gate closing in Kv channels. J. Biol. Chem. 287, 40091-40098
8. Ramu, Y., Xu, Y., and Lu, Z. (2006) Enzymatic activation of voltage-gated potassium channels. Nature 442, 696-699
9. + channels. Nature 451, 826-829
10. Combs, D. J., Shin, H. G., Xu, Y., Ramu, Y., and Lu, Z. (2013) Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase. J. Gen. Physiol. 142, 367-380
11. Zheng, H., Liu, W., Anderson, L. Y., and Jiang, Q. X. (2011) Lipid-dependent gating of a voltage-gated potassium channel. Nat. Commun. 2, 250
12. + channel in a lipid bilayer. Science 306, 491-495
13. Freites, J. A., Tobias, D. J., von Heijne, G., and White, S. H. (2005) Interface connections of a transmembrane voltage sensor. Proc. Natl. Acad. Sci. U. S. A. 102, 15059-15064
14. Börjesson, S. I., Parkkari, T., Hammarström, S., and Elinder, F. (2010) Electrostatic tuning of cellular excitability. Biophys. J. 98, 396-403
15. Payandeh, J., Scheuer, T., Zheng, N., and Catterall, W. A. (2011) The crystal structure of a voltage-gated sodium channel. Nature 475, 353-358
16. Krepkiy, D., Gawrisch, K., and Swartz, K. J. (2012) Structural interactions between lipids, water and S1-S4 voltage-sensing domains. J. Mol. Biol. 423, 632-647
17. Krepkiy, D., Mihailescu, M., Freites, J. A., Schow, E. V., Worcester, D. L., Gawrisch, K., Tobias, D. J., White, S. H., and Swartz, K. J. (2009) Structure and hydration of membranes embedded with voltage-sensing domains. Nature 462, 473-479
18. van der Cruijsen, E. A., Nand, D., Weingarth, M., Prokofyev, A., Hornig, S., Cukkemane, A. A., Bonvin, A. M., Becker, S., Hulse, R. E., Perozo, E., Pongs, O., and Baldus, M. (2013) Importance of lipid-pore loop interface for potassium channel structure and function. Proc. Natl. Acad. Sci. U. S. A. 110, 13008-13013
19. Weingarth, M., Prokofyev, A., van der Cruijsen, E. A., Nand, D., Bonvin, A. M., Pongs, O., and Baldus, M. (2013) Structural determinants of specific lipid binding to potassium channels. J. Am. Chem. Soc. 135, 3983-3988
20. Groulx, N., Juteau, M., and Blunck, R. (2010) Rapid topology probing using fluorescence spectroscopy in planar lipid bilayer: the pore-forming mechanism of the toxin Cry1Aa of Bacillus thuringiensis. J. Gen. Physiol. 136, 497-513
21. Gaede, H. C., and Gawrisch, K. (2003) Lateral diffusion rates of lipid, water, and a hydrophobic drug in a multilamellar liposome. Biophys. J. 85, 1734-1740
22. Zuidam, N. J., and Barenholz, Y. (1997) Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin. Biochim. Biophys. Acta 1329, 211-222
23. Jensen, M. O., Jogini, V., Borhani, D. W., Leffler, A. E., Dror, R. O., and Shaw, D. E. (2012) Mechanism of voltage gating in potassium channels. Science 336, 229-233
24. Abbott, G. W. (2006) Molecular mechanisms of cardiac voltage-gated potassium channelopathies. Curr. Pharm. Des. 12, 3631-3644
25. Börjesson, S. I., and Elinder, F. (2011) An electrostatic potassium channel opener targeting the final voltage sensor transition. J. Gen. Physiol. 137, 563-577
26. Milescu, M., Bosmans, F., Lee, S., Alabi, A. A., Kim, J. I., and Swartz, K. J. (2009) Interactions between lipids and voltage sensor paddles detected with tarantula toxins. Nat. Struct. Mol. Biol. 16, 1080-1085
27. + channel KvAP in DPhPC and POPE: POPG decane lipid bilayers. J. Mol. Biol. 390, 902-912
28. Kučerka, N., Nieh, M. P., and Katsaras, J. (2011) Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature. Biochim. Biophys. Acta 1808, 2761-2771
29. Heberle, F. A., Petruzielo, R. S., Pan, J., Drazba, P., Kučerka, N., Standaert, R. F., Feigenson, G. W., and Katsaras, J. (2013) Bilayer thickness mismatch controls domain size in model membranes. J. Am. Chem. Soc. 135, 6853-6859
30. Salvati, A., Ristori, S., Oberdisse, J., Spalla, O., Ricciardi, G., Pietrangeli, D., Giustini, M., and Martini, G. (2007) Small angle scattering and ζ potential of liposomes loaded with octa (carboranyl) porphyrazine. J. Phys. Chem. B 111, 10357-10364
31. + channels. J. Biol. Chem. 285, 14005-14019
32. Zagotta, W. N., Hoshi, T., Dittman, J., and Aldrich, R. W. (1994) Shaker potassium channel gating: II: transitions in the activation pathway. J. Gen. Physiol. 103, 279-319
33. Schoppa, N. E., McCormack, K., Tanouye, M. A., and Sigworth, F. J. (1992) The size of gating charge in wild-type and mutant Shaker potassium channels. Science 255, 1712-1715
34. Schoppa, N. E., and Sigworth, F. J. (1998) Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J. Gen. Physiol. 111, 313-342
35. Kalstrup, T., and Blunck, R. (2013) Dynamics of internal pore opening in KV channels probed by a fluorescent unnatural amino acid. Proc. Natl. Acad. Sci. U. S. A. 110, 8272-8277
36. Pathak, M., Kurtz, L., Tombola, F., and Isacoff, E. (2005) The cooperative voltage sensor motion that gates a potassium channel. J. Gen. Physiol. 125, 57-69
37. Ledwell, J. L., and Aldrich, R. W. (1999) Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J. Gen. Physiol. 113, 389-414
38. Smith-Maxwell, C. J., Ledwell, J. L., and Aldrich, R. W. (1998) Role of the S4 in cooperativity of voltage-dependent potassium channel activation. J. Gen. Physiol. 111, 399-420
39. Bähring, R., and Covarrubias, M. (2011) Mechanisms of closed-state inactivation in voltage-gated ion channels. J. Physiol. 589, 461-479
40. Payandeh, J., Gamal El-Din, T. M., Scheuer, T., Zheng, N., and Catterall, W. A. (2012) Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature 486, 135-139