메뉴 건너뛰기




Volumn 192, Issue 12, 2014, Pages 6045-6052

ARF6 inhibition stabilizes the vasculature and enhances survival During endotoxic shock

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MYELOID DIFFERENTIATION FACTOR 88;

EID: 84902156978     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400309     Document Type: Article
Times cited : (37)

References (50)
  • 2
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420:885-891.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 3
    • 77956635947 scopus 로고    scopus 로고
    • Sepsis and endothelial permeability
    • Lee, W. L., and A. S. Slutsky. 2010. Sepsis and endothelial permeability. N. Engl. J. Med. 363:689-691.
    • (2010) N. Engl. J. Med. , vol.363 , pp. 689-691
    • Lee, W.L.1    Slutsky, A.S.2
  • 4
    • 84873714375 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock, 2012
    • Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup
    • Dellinger, R. P., M. M. Levy, A. Rhodes, D. Annane, H. Gerlach, S. M. Opal, J. E. Sevransky, C. L. Sprung, I. S. Douglas, R. Jaeschke, et al; Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. 2013. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 39:165-228.
    • (2013) Intensive Care Med , vol.39 , pp. 165-228
    • Dellinger, R.P.1    Levy, M.M.2    Rhodes, A.3    Annane, D.4    Gerlach, H.5    Opal, S.M.6    Sevransky, J.E.7    Sprung, C.L.8    Douglas, I.S.9    Jaeschke, R.10
  • 6
    • 84883076264 scopus 로고    scopus 로고
    • Severe sepsis and septic shock
    • Angus, D. C., and T. Van Der Poll. 2013. Severe sepsis and septic shock. N. Engl. J. Med. 369:840-851.
    • (2013) N. Engl. J. Med. , vol.369 , pp. 840-851
    • Angus, D.C.1    Van Der Poll, T.2
  • 7
    • 0038578608 scopus 로고    scopus 로고
    • Novel strategies for the treatment of sepsis
    • Riedemann, N. C., R. F. Guo, and P. A. Ward. 2003. Novel strategies for the treatment of sepsis. Nat. Med. 9:517-524.
    • (2003) Nat. Med. , vol.9 , pp. 517-524
    • Riedemann, N.C.1    Guo, R.F.2    Ward, P.A.3
  • 8
    • 84859946349 scopus 로고    scopus 로고
    • Corticosteroids for severe sepsis: An evidence-based guide for physicians
    • Annane, D. 2011. Corticosteroids for severe sepsis: an evidence-based guide for physicians. Ann. Intensive care 1:7.
    • (2011) Ann. Intensive Care , vol.1 , pp. 7
    • Annane, D.1
  • 9
    • 84875124740 scopus 로고    scopus 로고
    • Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: The ACCESS randomized trial
    • ACCESS Study Group
    • Opal, S. M., P. F. Laterre, B. Francois, S. P. La Rosa, D. C. Angus, J. P. Mira, X. Wittebole, T. Dugernier, D. Perrotin, M. Tidswell, et al; ACCESS Study Group. 2013. Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA 309:1154-1162.
    • (2013) JAMA , vol.309 , pp. 1154-1162
    • Opal, S.M.1    Laterre, P.F.2    Francois, B.3    La Rosa, S.P.4    Angus, D.C.5    Mira, J.P.6    Wittebole, X.7    Dugernier, T.8    Perrotin, D.9    Tidswell, M.10
  • 10
    • 0034913364 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapy in sepsis: Update on clinical trials and lessons learned
    • Reinhart, K., and W. Karzai. 2001. Anti-tumor necrosis factor therapy in sepsis: update on clinical trials and lessons learned. Crit. Care Med. 29 (7, Suppl.) S121-S125.
    • (2001) Crit. Care Med. , vol.29 , Issue.7 SUPPL.
    • Reinhart, K.1    Karzai, W.2
  • 11
    • 0030877935 scopus 로고    scopus 로고
    • Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group
    • Opal, S. M., C. J. Fischer, Jr., J. F. Dhainaut, J. L. Vincent, R. Brase, S. F. Lowry, J. C. Sadoff, G. J. Slotman, H. Levy, R. A. Balk, et al 1997. Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit. Care Med. 25:1115-1124.
    • (1997) Crit. Care Med. , vol.25 , pp. 1115-1124
    • Opal, S.M.1    Fischer Jr., C.J.2    Dhainaut, J.F.3    Vincent, J.L.4    Brase, R.5    Lowry, S.F.6    Sadoff, J.C.7    Slotman, G.J.8    Levy, H.9    Balk, R.A.10
  • 12
  • 13
    • 39149097579 scopus 로고    scopus 로고
    • Host-pathogen interactions in sepsis
    • Van Der Poll, T., and S. M. Opal. 2008. Host-pathogen interactions in sepsis. Lancet Infect. Dis. 8:32-43.
    • (2008) Lancet Infect. Dis. , vol.8 , pp. 32-43
    • Van Der Poll, T.1    Opal, S.M.2
  • 14
    • 84871839728 scopus 로고    scopus 로고
    • MyD88: A critical adaptor protein in innate immunity signal transduction
    • Warner, N., and G. Núñez. 2013. MyD88: a critical adaptor protein in innate immunity signal transduction. J. Immunol. 190:3-4.
    • (2013) J. Immunol. , vol.190 , pp. 3-4
    • Warner, N.1    Núñez, G.2
  • 16
    • 52049120787 scopus 로고    scopus 로고
    • An assay system for in vitro detection of permeability in human "endothelium"
    • Martins-Green, M., M. Petreaca, and M. Yao. 2008. An assay system for in vitro detection of permeability in human "endothelium." Methods Enzymol. 443:137-153.
    • (2008) Methods Enzymol , vol.443 , pp. 137-153
    • Martins-Green, M.1    Petreaca, M.2    Yao, M.3
  • 17
    • 33750529948 scopus 로고    scopus 로고
    • VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin
    • Gavard, J., and J. S. Gutkind. 2006. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Nat. Cell Biol. 8:1223-1234.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1223-1234
    • Gavard, J.1    Gutkind, J.S.2
  • 18
    • 0023908222 scopus 로고
    • Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin
    • Moake, J. L., N. A. Turner, N. A. Stathopoulos, L. Nolasco, and J. D. Hellums. 1988. Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin. Blood 71:1366-1374.
    • (1988) Blood , vol.71 , pp. 1366-1374
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3    Nolasco, L.4    Hellums, J.D.5
  • 20
    • 0022337475 scopus 로고
    • Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro
    • Zimmerman, G. A., T. M. McIntyre, and S. M. Prescott. 1985. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J. Clin. Invest. 76:2235-2246.
    • (1985) J. Clin. Invest. , vol.76 , pp. 2235-2246
    • Zimmerman, G.A.1    McIntyre, T.M.2    Prescott, S.M.3
  • 21
    • 4544346050 scopus 로고    scopus 로고
    • Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: A mechanism for translational control of transcriptional events
    • Yost, C. C., M. M. Denis, S. Lindemann, F. J. Rubner, G. K. Marathe, M. Buerke, T. M. McIntyre, A. S. Weyrich, and G. A. Zimmerman. 2004. Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events. J. Exp. Med. 200:671-680.
    • (2004) J. Exp. Med. , vol.200 , pp. 671-680
    • Yost, C.C.1    Denis, M.M.2    Lindemann, S.3    Rubner, F.J.4    Marathe, G.K.5    Buerke, M.6    McIntyre, T.M.7    Weyrich, A.S.8    Zimmerman, G.A.9
  • 22
    • 0004045209 scopus 로고
    • Williams and Wilkins, Baltimore
    • Milnor, W. R. 1982. Hemodynamics. Williams and Wilkins, Baltimore.
    • (1982) Hemodynamics
    • Milnor, W.R.1
  • 23
    • 84886931464 scopus 로고    scopus 로고
    • An in vivo assay to test blood vessel permeability
    • Radu, M., and J. Chernoff. 2013. An in vivo assay to test blood vessel permeability. J. Vis. Exp. 16:e50062.
    • (2013) J. Vis. Exp. , vol.16
    • Radu, M.1    Chernoff, J.2
  • 24
    • 0036122075 scopus 로고    scopus 로고
    • Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor
    • Han, E. D., R. C. MacFarlane, A. N. Mulligan, J. Scafidi, and A. E. Davis, III. 2002. Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor. J. Clin. Invest. 109:1057-1063.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1057-1063
    • Han, E.D.1    MacFarlane, R.C.2    Mulligan, A.N.3    Scafidi, J.4    Davis III, A.E.5
  • 25
    • 77951212625 scopus 로고    scopus 로고
    • Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers
    • Adam, A. P., A. L. Sharenko, K. Pumiglia, and P. A. Vincent. 2010. Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J. Biol. Chem. 285:7045-7055.
    • (2010) J. Biol. Chem. , vol.285 , pp. 7045-7055
    • Adam, A.P.1    Sharenko, A.L.2    Pumiglia, K.3    Vincent, P.A.4
  • 26
    • 43149123808 scopus 로고    scopus 로고
    • Human skin endothelial cells can express all 10 TLR genes and respond to respective ligands
    • Fitzner, N., S. Clauberg, F. Essmann, J. Liebmann, and V. Kolb-Bachofen. 2008. Human skin endothelial cells can express all 10 TLR genes and respond to respective ligands. Clin. Vaccine Immunol. 15:138-146.
    • (2008) Clin. Vaccine Immunol. , vol.15 , pp. 138-146
    • Fitzner, N.1    Clauberg, S.2    Essmann, F.3    Liebmann, J.4    Kolb-Bachofen, V.5
  • 27
    • 84891051959 scopus 로고    scopus 로고
    • Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia
    • Zhao, H., A. R. Anand, and R. K. Ganju. 2014. Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia. J. Immunol. 192:385-393.
    • (2014) J. Immunol. , vol.192 , pp. 385-393
    • Zhao, H.1    Anand, A.R.2    Ganju, R.K.3
  • 28
    • 0034646695 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells
    • Faure, E., O. Equils, P. A. Sieling, L. Thomas, F. X. Zhang, C. J. Kirschning, N. Polentarutti, M. Muzio, and M. Arditi. 2000. Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J. Biol. Chem. 275:11058-11063.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11058-11063
    • Faure, E.1    Equils, O.2    Sieling, P.A.3    Thomas, L.4    Zhang, F.X.5    Kirschning, C.J.6    Polentarutti, N.7    Muzio, M.8    Arditi, M.9
  • 29
    • 76249121522 scopus 로고    scopus 로고
    • Cytohesin-1 regulates the Arf6-phospholipase D signaling axis in human neutrophils: Impact on superoxide anion production and secretion
    • El Azreq, M.-A., V. Garceau, D. Harbour, C. Pivot-Pajot, and S. G. Bourgoin. 2010. Cytohesin-1 regulates the Arf6-phospholipase D signaling axis in human neutrophils: impact on superoxide anion production and secretion. J. Immunol. 184:637-649.
    • (2010) J. Immunol. , vol.184 , pp. 637-649
    • El Azreq, M.-A.1    Garceau, V.2    Harbour, D.3    Pivot-Pajot, C.4    Bourgoin, S.G.5
  • 32
    • 0036709969 scopus 로고    scopus 로고
    • A universal role for MyD88 in TLR/IL-1Rmediated signaling
    • Janssens, S., and R. Beyaert. 2002. A universal role for MyD88 in TLR/IL-1Rmediated signaling. Trends Biochem. Sci. 27:474-482.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 474-482
    • Janssens, S.1    Beyaert, R.2
  • 33
    • 67649823926 scopus 로고    scopus 로고
    • Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: A distinct upstream kinase mediates Ser-172 phosphorylation and activation
    • Clark, K., L. Plater, M. Peggie, and P. Cohen. 2009. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. J. Biol. Chem. 284:14136-14146.
    • (2009) J. Biol. Chem. , vol.284 , pp. 14136-14146
    • Clark, K.1    Plater, L.2    Peggie, M.3    Cohen, P.4
  • 34
    • 0041355495 scopus 로고    scopus 로고
    • A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts
    • Kishore, N., C. Sommers, S. Mathialagan, J. Guzova, M. Yao, S. Hauser, K. Huynh, S. Bonar, C. Mielke, L. Albee, et al. 2003. A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts. J. Biol. Chem. 278:32861-32871.
    • (2003) J. Biol. Chem. , vol.278 , pp. 32861-32871
    • Kishore, N.1    Sommers, C.2    Mathialagan, S.3    Guzova, J.4    Yao, M.5    Hauser, S.6    Huynh, K.7    Bonar, S.8    Mielke, C.9    Albee, L.10
  • 35
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta, D., and A. B. Malik. 2006. Signaling mechanisms regulating endothelial permeability. Physiol. Rev. 86:279-367.
    • (2006) Physiol. Rev. , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 36
    • 33645736307 scopus 로고    scopus 로고
    • Arf6 plays an early role in platelet activation by collagen and convulxin
    • Choi, W., Z. A. Karim, and S. W. Whiteheart. 2006. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood 107:3145-3152.
    • (2006) Blood , vol.107 , pp. 3145-3152
    • Choi, W.1    Karim, Z.A.2    Whiteheart, S.W.3
  • 37
    • 0029007101 scopus 로고
    • The myristoylated amino terminus of ADP-ribosylation factor 1 is a phospholipid- and GTP-sensitive switch
    • Randazzo, P. A., T. Terui, S. Sturch, H. M. Fales, A. G. Ferrige, and R. A. Kahn. 1995. The myristoylated amino terminus of ADP-ribosylation factor 1 is a phospholipid- and GTP-sensitive switch. J. Biol. Chem. 270:14809-14815.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14809-14815
    • Randazzo, P.A.1    Terui, T.2    Sturch, S.3    Fales, H.M.4    Ferrige, A.G.5    Kahn, R.A.6
  • 38
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • Komarova, Y., and A. B. Malik. 2010. Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu. Rev. Physiol. 72:463-493.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 39
    • 37848998838 scopus 로고    scopus 로고
    • Angiopoietin-1 prevents VEGFinduced endothelial permeability by sequestering Src through mDia
    • Gavard, J., V. Patel, and J. S. Gutkind. 2008. Angiopoietin-1 prevents VEGFinduced endothelial permeability by sequestering Src through mDia. Dev. Cell 14:25-36.
    • (2008) Dev. Cell , vol.14 , pp. 25-36
    • Gavard, J.1    Patel, V.2    Gutkind, J.S.3
  • 41
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
    • Kagan, J. C., and R. Medzhitov. 2006. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125:943-955.
    • (2006) Cell , vol.125 , pp. 943-955
    • Kagan, J.C.1    Medzhitov, R.2
  • 47
    • 84865097997 scopus 로고    scopus 로고
    • ARF6-dependent regulation of P2Y receptor traffic and function in human platelets
    • Kanamarlapudi, V., S. E. Owens, K. Saha, R. J. Pope, and S. J. Mundell. 2012. ARF6-dependent regulation of P2Y receptor traffic and function in human platelets. PLoS ONE 7:e43532.
    • (2012) PLoS ONE , vol.7
    • Kanamarlapudi, V.1    Owens, S.E.2    Saha, K.3    Pope, R.J.4    Mundell, S.J.5
  • 50
    • 0344961161 scopus 로고    scopus 로고
    • Blood-brain barrier disruption in multiple sclerosis
    • Minagar, A., and J. S. Alexander. 2003. Blood-brain barrier disruption in multiple sclerosis. Mult. Scler. 9:540-549
    • (2003) Mult. Scler. , vol.9 , pp. 540-549
    • Minagar, A.1    Alexander, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.