Down-regulation of GRP78 enhances apoptosis via CHOP pathway in retinal ischemia-reperfusion injury

Neuroscience Letters

Volumn 575, Issue , 2014, Pages 68-73

  Li, Huiling ^a   Zhu, Xiaohua ^a   Fang, Fang ^a   Jiang, Deyong ^b   Tang, Luosheng ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Boya Eye Hospital   (China)

Author keywords

Antisense oligonucleotide; Apoptosis; CHOP; Endoplasmic reticulum stress; GRP78; Retinal ischemia reperfusion

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; DDIT3 PROTEIN, RAT; HEAT SHOCK PROTEIN; HSPA5 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; RETINA INJURY; RETINA ISCHEMIA; UPREGULATION; ANIMAL; GENETICS; METABOLISM; PATHOLOGY; RETINA; RETINA DISEASE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; MALE; OLIGONUCLEOTIDES, ANTISENSE; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RETINA; RETINAL DISEASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 84902143204     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.05.042     Document Type: Article

References (29)

1. Katsimpris J.M., Petropoulos I.K., Pournaras C.J. Ocular pulse amplitude measurement after retinal detachment surgery. Klin. Monbl. Augenheilkd. 2003, 220:127-130.
2. Osborne N.N., Casson R.J., Wood J.P., Chidlow G., Graham M., Melena J. Retinal ischemia mechanisms of damage and potential therapeutic strategies. Prog. Retin. Eye Res. 2004, 23:91-147.
3. Buchi E.R. Cell death in the rat retina after a pressure-induced ischaemia-reperfusion insult: an electron microscopic study. I. Ganglion cell layer and inner nuclear layer. Exp. Eye Res. 1992, 55:605-613.
4. Bonne C., Muller A., Villain M. Free radicals in retinal ischemia. Gen. Pharmacol. 1998, 30:275-280.
5. Takahashi R., Imai Y. Pael receptor, endoplasmic reticulum stress, and Parkinson's disease. J. Neurol. 2003, 250(Suppl. 3):I25-I29.
6. Taylor J.P., Hardy J., Fischbeck K.H. Toxic proteins in neurodegenerative disease. Science 2002, 296:1991-1995.
7. Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 2007, 8:519-529.
8. Gorlach A., Klappa P., Kietzmann T. The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid. Redox Signal. 2006, 8:1391-1418.
9. Bertolotti A., Zhang Y., Hendershot L.M., Harding H.P., Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2000, 2:326-332.
10. Kawahara K., Oyadomari S., Gotoh T., Kohsaka S., Nakayama H., Mori M. Induction of CHOP and apoptosis by nitric oxide in P53-deficient microglial cells. FEBS Lett. 2001, 506:135-139.
11. Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
12. Tajiri S., Oyadomari S., Yano S., Morioka M., Gotoh T., Hamada J.I., Ushio Y., Mori M. Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving chop. Cell Death Differ. 2004, 11:403-415.
13. Awai M., Koga T., Inomata Y., Oyadomari S., Gotoh T., Mori M., Tanihara H. NMDA-induced retinal injury is mediated by an endoplasmic reticulum stress-related protein, CHOP/GADD153. J. Neurochem. 2006, 96:43-52.
14. Doh S.H., Kim J.H., Lee K.M., Park H.Y., Park C.K. Retinal ganglion cell death induced by endoplasmic reticulum stress in a chronic glaucoma model. Brain Res. 2010, 1308:158-166.
15. Ryoo H.D., Domingos P.M., Kang M.J., Steller H. Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J. 2007, 26:242-252.
16. Shimazawa M., Inokuchi Y., Ito Y., Murata H., Aihara M., Miura M., Araie M., Hara H. Involvement of ER stress in retinal cell death. Mol. Vis. 2007, 13:578-587.
17. Hammond C., Helenius A. Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus. J. Cell Biol. 1994, 126:41-52.
18. Rao R.V., Bredesen D.E. Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr. Opin. Cell Biol. 2004, 16:653-662.
19. Li J., Wang J.J., Yu Q., Wang M., Zhang S.X. Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. FEBS Lett. 2009, 583:1521-1527.
20. Buchi E.R., Suivaizdis I., Fu J. Pressure-induced retinal ischemia in rats: an experimental model for quantitative study. Ophthalmologica 1991, 203:138-147.
21. Nucci C., Gasperi V., Tartaglione R., Cerulli A., Terrinoni A., Bari M., De Simone C., Agro A.F., Morrone L.A., Corasaniti M.T., Bagetta G., Maccarrone M. Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. Invest. Ophthalmol. Vis. Sci. 2007, 48:2997-3004.
22. Oida Y., Shimazawa M., Imaizumi K., Hara H. Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil. Neuroscience 2008, 151:111-119.
23. Prachasilchai W., Sonoda H., Yokota-Ikeda N., Oshikawa S., Aikawa C., Uchida K., Ito K., Kudo T., Imaizumi K., Ikeda M. A protective role of unfolded protein response in mouse ischemic acute kidney injury. Eur. J. Pharmacol. 2008, 592:138-145.
24. Karar J., Dolt K.S., Qadar Pasha M.A. Endoplasmic reticulum stress response in murine kidney exposed to acute hypobaric hypoxia. FEBS Lett. 2008, 582:2521-2526.
25. Hayashi T., Saito A., Okuno S., Ferrand-Drake M., Dodd R.L., Chan P.H. Oxidative injury to the endoplasmic reticulum in mouse brains after transient focal ischemia. Neurobiol. Dis. 2004, 15:229-239.
26. Inokuchi Y., Nakajima Y., Shimazawa M., Kurita T., Kubo M., Saito A., Sajiki H., Kudo T., Aihara M., Imaizumi K., Araie M., Hara H. Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death. Invest. Ophthalmol. Vis. Sci. 2009, 50:334-344.
27. Yu Z., Luo H., Fu W., Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 1999, 155:302-314.
28. Pan Y.X., Lin L., Ren A.J., Pan X.J., Chen H., Tang C.S., Yuan W.J. HSP70 and GRP78 induced by endothelin-1 pretreatment enhance tolerance to hypoxia in cultured neonatal rat cardiomyocytes. J. Cardiovasc. Pharmacol. 2004, 44(Suppl. 1):S117-S120.
29. 2+ disturbances, and cell death in renal epithelial cells. J. Biol. Chem. 1997, 272:21751-21759.