Tumour necrosis factor-α inhibition with lenalidomide alleviates tissue oxidative injury and apoptosis in ob/ob obese mice

Clinical and Experimental Pharmacology and Physiology

Volumn 41, Issue 7, 2014, Pages 489-501

  Zhu, Xiaoling ^a,b   Jiang, Shasha ^b,c   Hu, Nan ^b   Luo, Fuling ^b   Dong, Hailong ^a   Kang, Yu Ming ^d   Jones, Kyla R ^b   Zou, Yunzeng ^c   Xiong, Lize ^a   Ren, Jun ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

^c FUDAN UNIVERSITY   (China)

^d MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Lenalidomide; Oxidative injury; Protein damage; Tumour necrosis factor

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE; GLUTATHIONE DISULFIDE; INTERLEUKIN 6; LENALIDOMIDE; PROTEIN BAX; PROTEIN BCL 2; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; GLUCOSE BLOOD LEVEL; IMMUNOLOGIC FACTOR; THALIDOMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CYTOKINE PRODUCTION; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; KIDNEY; LIPID PEROXIDATION; LIVER; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN EXPRESSION; SMALL INTESTINE; TISSUE INJURY; TISSUE OXIDATIVE INJURY; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; SKELETAL MUSCLE;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; GENE EXPRESSION REGULATION; GLUCOSE; IMMUNOLOGIC FACTORS; INTESTINE, SMALL; KIDNEY; MICE; MICE, OBESE; MUSCLE, SKELETAL; OBESITY; OXIDATIVE STRESS; THALIDOMIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84902140474     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12240     Document Type: Article

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