Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes

Diabetes

Volumn 61, Issue 8, 2012, Pages 2134-2145

  Wang, Zongwei ^a   Cheng, Zhiyong ^b   Cristofaro, Vivian ^c   Li, Jijun ^a,d   Xiao, Xingyuan ^a,e   Gomez, Pablo ^b   Ge, Rongbin ^a   Gong, Edward ^b   Strle, Klemen ^a   Sullivan, Maryrose P ^c   Adam, Rosalyn M ^b   White, Morris F ^b   Olumi, Aria F ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; METFORMIN; MYOSIN LIGHT CHAIN; RHO KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; BLADDER DYSFUNCTION; BLADDER FILLING; CLINICAL FEATURE; CONTROLLED STUDY; DIABETIC BLADDER DYSFUNCTION; DRUG POTENTIATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; FEMALE; GENE DELETION; GENE INACTIVATION; HYPERGLYCEMIA; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; UPREGULATION; URINE VOLUME;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; INSULIN RECEPTOR SUBSTRATE PROTEINS; METFORMIN; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MYOSIN LIGHT CHAINS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RHO-ASSOCIATED KINASES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; URINARY BLADDER; URINARY BLADDER DISEASES; URINARY BLADDER, OVERACTIVE;

EID: 84864390275     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1763     Document Type: Article

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