Synthesis and evaluation of a targeted nanoglobular dual-modal imaging agent for MR imaging and image-guided surgery of prostate cancer

Pharmaceutical Research

Volumn 31, Issue 6, 2014, Pages 1469-1476

  Tan, Mingqian ^a,b   Ye, Zhen ^a   Lindner, Daniel ^c   Brady Kalnay, Susann M ^d   Lu, Zheng Rong ^a  

^a Case Western Reserve University   (United States)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c LERNER RESEARCH INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

contrast agent; dual modal imaging agent; fluorescence imaging; image guided surgery; MRI

Indexed keywords

DENDRIMER; GADOLINIUM; NANOCONJUGATE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; POLYLYSINE; POLYPEPTIDE; TETRAXETAN; CARBOCYANINE; CONTRAST MEDIUM; CYANINE DYE 5; FLUORESCENT DYE; GADOLINIUM 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER TISSUE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG CONJUGATION; DRUG SYNTHESIS; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IMAGE GUIDED SURGERY; IMAGING SYSTEM; MALE; MOUSE; NANOIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; NUDE MOUSE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE SURGERY; SIGNAL NOISE RATIO; SURGICAL TECHNIQUE; ANIMAL; CHEMISTRY; COMPUTER ASSISTED SURGERY; DEVICES; FLUORESCENCE; PATHOLOGY; PROCEDURES; PROSTATIC NEOPLASMS; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; CARBOCYANINES; CELL LINE, TUMOR; CONTRAST MEDIA; FLUORESCENCE; FLUORESCENT DYES; HETEROCYCLIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, NUDE; ORGANOMETALLIC COMPOUNDS; PROSTATIC NEOPLASMS; SURGERY, COMPUTER-ASSISTED;

EID: 84902139093     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1008-5     Document Type: Article

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