Sugars as bulking agents to prevent nano-crystal aggregation during spray or freeze-drying

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 303-311

  Kumar, Sumit ^a   Gokhale, Rajeev ^b   Burgess, Diane J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b ABBVIE INC   (United States)

Author keywords

Freeze drying; Nano crystal powder; Nano crystalline suspension; Spray drying; Sugars

Indexed keywords

BULKING AGENT; CARBOHYDRATE; DISACCHARIDE; INDOMETACIN; NANOCRYSTAL; POLYSACCHARIDE; SUGAR ALCOHOL; EXCIPIENT; NANOPARTICLE;

ARTICLE; CONTACT ANGLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; INFRARED SPECTROSCOPY; MEASUREMENT; MOLECULAR WEIGHT; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; SPRAY DRYING; TECHNOLOGY; X RAY DIFFRACTION; CHEMISTRY; CRYSTALLIZATION; PROCEDURES;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBOHYDRATES; CRYSTALLIZATION; DRUG COMPOUNDING; EXCIPIENTS; FREEZE DRYING; INDOMETHACIN; NANOPARTICLES; PARTICLE SIZE;

EID: 84902122556     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.060     Document Type: Article

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