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Volumn 4, Issue , 2014, Pages

Bax inhibitor-1-mediated inhibition of mitochondrial Ca2+ intake regulates mitochondrial permeability transition pore opening and cell death

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CALCIUM; CARRIER PROTEIN; CYTOCHROME C; MEMBRANE PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; TMBIM6 PROTEIN, HUMAN;

EID: 84902105427     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05194     Document Type: Article
Times cited : (32)

References (66)
  • 1
    • 0036877142 scopus 로고    scopus 로고
    • The endoplasmic reticulum:A multifunctional signaling organelle
    • Berridge, M. J. The endoplasmic reticulum:A ultifunctional signaling organelle.Cell Calcium 32, 235-49 (2002).
    • (2002) Cell Calcium , vol.32 , pp. 235-249
    • Berridge, M.J.1
  • 2
    • 4444234264 scopus 로고    scopus 로고
    • Ribosome-translocon complex mediates calcium leakagefrom endoplasmic reticulum stores
    • Van Coppenolle, F. et al. Ribosome-translocon complex mediates calcium leakagefrom endoplasmic reticulum stores. J Cell Sci 117, 4135-42 (2004).
    • (2004) J Cell Sci , vol.117 , pp. 4135-4142
    • Van Coppenolle, F.1
  • 3
    • 54949110895 scopus 로고    scopus 로고
    • Calcium andapoptosis: ER-mitochondria Ca21 transfer in the control of apoptosis
    • Pinton, P., Giorgi, C., Siviero, R., Zecchini, E. & Rizzuto, R. Calcium andapoptosis: ER-mitochondria Ca21 transfer in the control of apoptosis. Oncogene27, 6407-18 (2008).
    • (2008) Oncogene , vol.27 , pp. 6407-6418
    • Pinton, P.1    Giorgi, C.2    Siviero, R.3    Zecchini, E.4    Rizzuto, R.5
  • 4
    • 84856547009 scopus 로고    scopus 로고
    • Mitochondrial calcium homeostasis as potential target formitochondrial medicine
    • Giorgi, C. et al. Mitochondrial calcium homeostasis as potential target formitochondrial medicine. Mitochondrion 12, 77-85 (2012).
    • (2012) Mitochondrion , vol.12 , pp. 77-85
    • Giorgi, C.1
  • 5
    • 84893247772 scopus 로고    scopus 로고
    • Measurement of mitochondrialca21 transport mediated by three transport proteins: Vdac1, the na1/ca21 exchanger, and the ca21 uniporter
    • Ben-Hail, D., Palty, R. & Shoshan-Barmatz, V. Measurement of MitochondrialCa21 Transport Mediated by Three Transport Proteins: VDAC1, the Na1/Ca21 Exchanger, and the Ca21 Uniporter. Cold Spring Harb Protoc 2, 161-166(2014).
    • (2014) Cold Spring Harb Protoc , vol.2 , pp. 161-166
    • Ben-Hail, D.1    Palty, R.2    Shoshan-Barmatz, V.3
  • 6
    • 33745958168 scopus 로고    scopus 로고
    • Bcl-2 and Ca21 homeostasis in the endoplasmicreticulum
    • Pinton, P. & Rizzuto, R. Bcl-2 and Ca21 homeostasis in the endoplasmicreticulum. Cell Death Differ 13, 1409-18 (2006).
    • (2006) Cell Death Differ , vol.13 , pp. 1409-1418
    • Pinton, P.1    Rizzuto, R.2
  • 7
    • 33947394480 scopus 로고    scopus 로고
    • Bax and the mitochondrial permeability transitioncooperate in the release of cytochrome c during endoplasmic reticulum-stressinducedapoptosis
    • Zhang, D. & Armstrong, J. S. Bax and the mitochondrial permeability transitioncooperate in the release of cytochrome c during endoplasmic reticulum-stressinducedapoptosis. Cell Death Differ 14, 703-15 (2007).
    • (2007) Cell Death Differ , vol.14 , pp. 703-715
    • Zhang, D.1    Armstrong, J.S.2
  • 8
    • 4143087106 scopus 로고    scopus 로고
    • BI-1 regulates an apoptosis pathway linked to endoplasmicreticulum stress
    • Chae, H. J. et al. BI-1 regulates an apoptosis pathway linked to endoplasmicreticulum stress. Mol Cell 15, 355-66 (2004).
    • (2004) Mol Cell , vol.15 , pp. 355-366
    • Chae, H.J.1
  • 9
    • 33644515957 scopus 로고    scopus 로고
    • Cytoprotective gene bi-1 is required for intrinsic protectionfrom endoplasmic reticulum stress and ischemia-reperfusion injury
    • Bailly-Maitre, B. et al. Cytoprotective gene bi-1 is required for intrinsic protectionfrom endoplasmic reticulum stress and ischemia-reperfusion injury. Proc NatlAcad Sci USA 103, 2809-14 (2006).
    • (2006) Proc NatlAcad Sci USA , vol.103 , pp. 2809-2814
    • Bailly-Maitre, B.1
  • 10
    • 34547607269 scopus 로고    scopus 로고
    • Bax inhibitor-1 regulates endoplasmic reticulum stress-associatedreactive oxygen species and heme oxygenase-1 expression
    • Lee, G. H. et al. Bax inhibitor-1 regulates endoplasmic reticulum stress-associatedreactive oxygen species and heme oxygenase-1 expression. J Biol Chem 282,21618-28 (2007).
    • (2007) J Biol Chem , vol.282 , pp. 21618-21628
    • Lee, G.H.1
  • 11
    • 47049128540 scopus 로고    scopus 로고
    • Bax Inhibitor-1 Is a pH-dependent regulator of Ca21 channelactivity in the endoplasmic reticulum
    • Kim, H. R. et al. Bax Inhibitor-1 Is a pH-dependent regulator of Ca21 channelactivity in the endoplasmic reticulum. J Biol Chem 283, 15946-55 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 15946-15955
    • Kim, H.R.1
  • 12
    • 45549102988 scopus 로고    scopus 로고
    • BI-1 regulates endoplasmic reticulumCa21 homeostasis downstream of Bcl-2 family proteins
    • Xu, C., Xu, W., Palmer, A. E. & Reed, J. C. BI-1 regulates endoplasmic reticulumCa21 homeostasis downstream of Bcl-2 family proteins. J Biol Chem 283,11477-84 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 11477-11484
    • Xu, C.1    Xu, W.2    Palmer, A.E.3    Reed, J.C.4
  • 13
    • 38049162500 scopus 로고    scopus 로고
    • Involvement of mitochondria in endoplasmic reticulum stressinducedapoptotic cell death pathway triggered by the prion peptide PrP(106-126)
    • Ferreiro, E. et al. Involvement of mitochondria in endoplasmic reticulum stressinducedapoptotic cell death pathway triggered by the prion peptide PrP(106-126). J Neurochem 104, 766-76 (2008).
    • (2008) J Neurochem , vol.104 , pp. 766-776
    • Ferreiro, E.1
  • 15
    • 21744457239 scopus 로고    scopus 로고
    • Role of mitochondrial re-energization and Ca21influx in reperfusion injury of metabolically inhibited cardiac myocytes
    • Rodrigo, G. C. & Standen, N. B. Role of mitochondrial re-energization and Ca21influx in reperfusion injury of metabolically inhibited cardiac myocytes.Cardiovasc Res 67, 291-300 (2005).
    • (2005) Cardiovasc Res , vol.67 , pp. 291-300
    • Rodrigo, G.C.1    Standen, N.B.2
  • 16
    • 38449096946 scopus 로고    scopus 로고
    • Endothelialmitochondria as a possible target for potassium channel modulators
    • Glab, M., Lojek, A., Wrzosek, A., Dolowy, K. & Szewczyk, A. Endothelialmitochondria as a possible target for potassium channel modulators. PharmacolRep 58 Suppl, 89-95 (2006).
    • (2006) PharmacolRep , vol.58 , Issue.SUPPL. , pp. 89-95
    • Glab, M.1    Lojek, A.2    Wrzosek, A.3    Dolowy, K.4    Szewczyk, A.5
  • 17
    • 34548685366 scopus 로고    scopus 로고
    • The Bax lnhibitor-1 needs a functional electron transport chainfor cell death suppression
    • Oshima, R. et al. The Bax lnhibitor-1 needs a functional electron transport chainfor cell death suppression. FEBS Lett 581, 4627-32 (2007).
    • (2007) FEBS Lett , vol.581 , pp. 4627-4632
    • Oshima, R.1
  • 18
    • 77950865511 scopus 로고    scopus 로고
    • BAX inhibitor-1 enhances cancer metastasis by altering glucosemetabolism and activating the sodium-hydrogen exchanger: The alteration ofmitochondrial function
    • Lee, G. H. et al. BAX inhibitor-1 enhances cancer metastasis by altering glucosemetabolism and activating the sodium-hydrogen exchanger: the alteration ofmitochondrial function. Oncogene 29, 2130-41 (2010).
    • (2010) Oncogene , vol.29 , pp. 2130-2141
    • Lee, G.H.1
  • 19
    • 70350012303 scopus 로고    scopus 로고
    • Isolation of mitochondria-associated membranes and mitochondria from animaltissues and cells
    • Wieckowski, M. R., Giorgi, C., Lebiedzinska, M., Duszynski, J. & Pinton, P.Isolation of mitochondria-associated membranes and mitochondria from animaltissues and cells. Nat Protoc 4, 1582-90 (2009).
    • (2009) Nat Protoc , vol.4 , pp. 1582-1590
    • Wieckowski, M.R.1    Giorgi, C.2    Lebiedzinska, M.3    Duszynski, J.4    Pinton, P.5
  • 20
    • 84875365804 scopus 로고    scopus 로고
    • Autophagosomes form at ER-mitochondria contact sites
    • Hamasaki, M. et al. Autophagosomes form at ER-mitochondria contact sites.Nature 495, 389-93 (2013).
    • (2013) Nature , vol.495 , pp. 389-393
    • Hamasaki, M.1
  • 21
    • 84887589243 scopus 로고    scopus 로고
    • Identification of PTEN at the ER and MAMs and its regulation ofCa(21) signaling and apoptosis in a protein phosphatase-dependentmanner
    • Bononi, A. et al. Identification of PTEN at the ER and MAMs and its regulation ofCa(21) signaling and apoptosis in a protein phosphatase- dependentmanner. CellDeath Differ 20, 1631-43 (2013).
    • (2013) CellDeath Differ , vol.20 , pp. 1631-1643
    • Bononi, A.1
  • 22
    • 78651364538 scopus 로고    scopus 로고
    • Endoplasmic reticulum protein BI-1 modulates unfoldedprotein response signaling and protects against stroke and traumatic brain injury
    • Krajewska, M. et al. Endoplasmic reticulum protein BI-1 modulates unfoldedprotein response signaling and protects against stroke and traumatic brain injury.Brain Res 1370, 227-37 (2011).
    • (2011) Brain Res , vol.1370 , pp. 227-237
    • Krajewska, M.1
  • 23
    • 33748935959 scopus 로고    scopus 로고
    • Inhibition of Ca21influx is requiredfor mitochondrial reactive oxygen species-induced endoplasmic reticulum Ca21depletion and cell death in leukemia cells
    • Zhang, Y., Soboloff, J., Zhu, Z.&Berger, S. A. Inhibition of Ca21influx is requiredfor mitochondrial reactive oxygen species-induced endoplasmic reticulum Ca21depletion and cell death in leukemia cells. Mol Pharmacol 70, 1424-34 (2006).
    • (2006) Mol Pharmacol , vol.70 , pp. 1424-1434
    • Zhang, Y.1    Soboloff, J.2    Zhu, Z.3    Berger, S.A.4
  • 24
    • 38849119213 scopus 로고    scopus 로고
    • Calcium and cell death: The mitochondrial connection
    • Bernardi, P. & Rasola, A. Calcium and cell death: the mitochondrial connection.Subcell Biochem 45, 481-506 (2007).
    • (2007) Subcell Biochem , vol.45 , pp. 481-506
    • Bernardi, P.1    Rasola, A.2
  • 25
    • 38049155818 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces calcium-dependentpermeability transition, mitochondrial outer membrane permeabilization andapoptosis
    • Deniaud, A. et al. Endoplasmic reticulum stress induces calcium-dependentpermeability transition, mitochondrial outer membrane permeabilization andapoptosis. Oncogene 27, 285-99 (2008).
    • (2008) Oncogene , vol.27 , pp. 285-299
    • Deniaud, A.1
  • 26
    • 0141483378 scopus 로고    scopus 로고
    • Cholesterol impairs the adenine nucleotide translocator- mediatedmitochondrial permeability transition through altered membrane fluidity
    • Colell, A. et al. Cholesterol impairs the adenine nucleotide translocator-mediatedmitochondrial permeability transition through altered membrane fluidity. J BiolChem 278, 33928-35 (2003).
    • (2003) J BiolChem , vol.278 , pp. 33928-33935
    • Colell, A.1
  • 27
    • 32644447491 scopus 로고    scopus 로고
    • Release of cytochrome c from isolated mitochondria byetoposide
    • Park, J. H. & Kim, T. H. Release of cytochrome c from isolated mitochondria byetoposide. J Biochem Mol Biol 38, 619-23 (2005).
    • (2005) J Biochem Mol Biol , vol.38 , pp. 619-623
    • Park, J.H.1    Kim, T.H.2
  • 28
    • 0034671720 scopus 로고    scopus 로고
    • Bid-inducedcytochrome c release is mediated by a pathway independent of mitochondrialpermeability transition pore and Bax
    • Kim, T. H., Zhao, Y., Barber, M. J., Kuharsky, D. K. & Yin, X. M. Bid-inducedcytochrome c release is mediated by a pathway independent of mitochondrialpermeability transition pore and Bax. J Biol Chem 275, 39474-81 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 39474-39481
    • Kim, T.H.1    Zhao, Y.2    Barber, M.J.3    Kuharsky, D.K.4    Yin, X.M.5
  • 29
    • 0032874056 scopus 로고    scopus 로고
    • Adaptation of mouse skeletalmuscle to a novel functional overload test: Changes in myosin heavy chains andSERCA and physiological consequences
    • Awede, B., Berquin, A., Wuytack, F. & Lebacq, J. Adaptation of mouse skeletalmuscle to a novel functional overload test: changes in myosin heavy chains andSERCA and physiological consequences. Eur J Appl Physiol Occup Physiol 80,519-26 (1999).
    • (1999) Eur J Appl Physiol Occup Physiol , vol.80 , pp. 519-526
    • Awede, B.1    Berquin, A.2    Wuytack, F.3    Lebacq, J.4
  • 30
    • 0032514223 scopus 로고    scopus 로고
    • Modulation of mitochondrial ATPdependentK1 channels by protein kinase C
    • Sato, T., O'Rourke, B. & Marban, E. Modulation of mitochondrial ATPdependentK1 channels by protein kinase C. Circ Res 83, 110-4 (1998).
    • (1998) Circ Res , vol.83 , pp. 110-114
    • Sato, T.1    O'Rourke, B.2    Marban, E.3
  • 31
    • 74049131721 scopus 로고    scopus 로고
    • Potassium channels in brain mitochondria
    • Bednarczyk, P. Potassium channels in brain mitochondria. Acta Biochim Pol 56,385-92 (2009).
    • (2009) Acta Biochim Pol , vol.56 , pp. 385-392
    • Bednarczyk, P.1
  • 32
    • 63449092000 scopus 로고    scopus 로고
    • Calcium ions regulate K(1) uptake into brain mitochondria: Theevidence for a novel potassium channel
    • Skalska, J. et al. Calcium ions regulate K(1) uptake into brain mitochondria: theevidence for a novel potassium channel. Int J Mol Sci 10, 1104-20 (2009).
    • (2009) Int J Mol Sci , vol.10 , pp. 1104-1120
    • Skalska, J.1
  • 33
    • 1542343927 scopus 로고    scopus 로고
    • Evidence for mitochondrial K1 channels and their role incardioprotection
    • O'Rourke, B. Evidence for mitochondrial K1 channels and their role incardioprotection. Circ Res 94, 420-32 (2004).
    • (2004) Circ Res , vol.94 , pp. 420-432
    • O'Rourke, B.1
  • 34
    • 0032560651 scopus 로고    scopus 로고
    • Mitochondrial ATP-dependentpotassium channels: Novel effectors of cardioprotection
    • Liu, Y., Sato, T., O'Rourke, B. & Marban, E. Mitochondrial ATP-dependentpotassium channels: novel effectors of cardioprotection Circulation 97, 2463-9(1998).
    • (1998) Circulation , vol.97 , pp. 2463-2469
    • Liu, Y.1    Sato, T.2    O'Rourke, B.3    Marban, E.4
  • 35
    • 6444236250 scopus 로고    scopus 로고
    • Protein kinase Cinhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes
    • Kohro, S., Hogan, Q. H., Warltier, D. C. & Bosnjak, Z. J. Protein kinase Cinhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes.Anesth Analg 99, 1316-22 (2004).
    • (2004) Anesth Analg , vol.99 , pp. 1316-1322
    • Kohro, S.1    Hogan, Q.H.2    Warltier, D.C.3    Bosnjak, Z.J.4
  • 36
    • 44949247416 scopus 로고    scopus 로고
    • Effect of diazoxide on flavoprotein oxidation and reactive oxygenspecies generation during ischemia-reperfusion: A study on Langendorff-perfusedrat hearts using optic fibers
    • Pasdois, P. et al. Effect of diazoxide on flavoprotein oxidation and reactive oxygenspecies generation during ischemia-reperfusion: A study on Langendorff-perfusedrat hearts using optic fibers. Am J Physiol Heart Circ Physiol 294, H2088-97(2008).
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Pasdois, P.1
  • 37
    • 84861122472 scopus 로고    scopus 로고
    • Endoplasmic reticulum protein BI-1 regulates Ca(2)(1)- mediatedbioenergetics to promote autophagy
    • Sano, R. et al. Endoplasmic reticulum protein BI-1 regulates Ca(2)(1)-mediatedbioenergetics to promote autophagy. Genes Dev 26, 1041-54 (2012).
    • (2012) Genes Dev , vol.26 , pp. 1041-1054
    • Sano, R.1
  • 38
    • 33746594831 scopus 로고    scopus 로고
    • A role for mitochondrial aquaporins in cellular lifeand-death decisions
    • Lee, W. K. & Thevenod, F. A role for mitochondrial aquaporins in cellular lifeand-death decisions Am J Physiol Cell Physiol 291, C195-202 (2006).
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Lee, W.K.1    Thevenod, F.2
  • 39
    • 84871726622 scopus 로고    scopus 로고
    • Where the endoplasmic reticulum and themitochondrion tie the knot: The mitochondria-associated membrane (MAM)
    • Raturi, A. & Simmen, T. Where the endoplasmic reticulum and themitochondrion tie the knot: the mitochondria-associated membrane (MAM).Biochim Biophys Acta 1833, 213-24 (2013).
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 213-224
    • Raturi, A.1    Simmen, T.2
  • 40
    • 68649115556 scopus 로고    scopus 로고
    • Ca(21) transfer from the ER to mitochondria: When, how andwhy
    • Rizzuto, R. et al. Ca(21) transfer from the ER to mitochondria: when, how andwhy. Biochim Biophys Acta 1787, 1342-51 (2009).
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1342-1351
    • Rizzuto, R.1
  • 41
    • 0034668833 scopus 로고    scopus 로고
    • Mitochondria and calcium: From cell signalling to cell death
    • Duchen, M. R. Mitochondria and calcium: from cell signalling to cell death.J Physiol 529, 57-68 (2000).
    • (2000) J Physiol , vol.529 , Issue.1 , pp. 57-68
    • Duchen, M.R.1
  • 42
    • 78149450143 scopus 로고    scopus 로고
    • Characterization of membranepotential dependency of mitochondrial Ca21uptake by an improved biophysicalmodel of mitochondrial Ca21 uniporter
    • Pradhan, R. K., Qi, F., Beard, D. A. & Dash, R. K. Characterization of membranepotential dependency of mitochondrial Ca21uptake by an improved biophysicalmodel of mitochondrial Ca21 uniporter. PLoS One 5, e13278 (2010).
    • (2010) PLoS One , vol.5
    • Pradhan, R.K.1    Qi, F.2    Beard, D.A.3    Dash, R.K.4
  • 43
    • 77953811579 scopus 로고    scopus 로고
    • The regulation of OXPHOS by extramitochondrial calcium
    • Gellerich, F. N. et al. The regulation of OXPHOS by extramitochondrial calcium.Biochim Biophys Acta 1797, 1018-27 (2010).
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 1018-1027
    • Gellerich, F.N.1
  • 44
    • 70449088871 scopus 로고    scopus 로고
    • GM1-ganglioside accumulation at the mitochondria-associated ERmembranes links ER stress to Ca(21)-dependent mitochondrial apoptosis
    • Sano, R. et al. GM1-ganglioside accumulation at the mitochondria- associated ERmembranes links ER stress to Ca(21)-dependent mitochondrial apoptosis. MolCell 36, 500-11 (2009).
    • (2009) MolCell , vol.36 , pp. 500-511
    • Sano, R.1
  • 45
    • 0035163738 scopus 로고    scopus 로고
    • Roles ofphosphatidylethanolamine and of its several biosynthetic pathways inSaccharomyces cerevisiae
    • Birner, R., Burgermeister, M., Schneiter, R. & Daum, G. Roles ofphosphatidylethanolamine and of its several biosynthetic pathways inSaccharomyces cerevisiae. Mol Biol Cell 12, 997-1007 (2001).
    • (2001) Mol Biol Cell , vol.12 , pp. 997-1007
    • Birner, R.1    Burgermeister, M.2    Schneiter, R.3    Daum, G.4
  • 46
    • 28844440297 scopus 로고    scopus 로고
    • Disruption of the phosphatidylserine decarboxylase gene inmice causes embryonic lethality and mitochondrial defects
    • Steenbergen, R. et al. Disruption of the phosphatidylserine decarboxylase gene inmice causes embryonic lethality and mitochondrial defects. J Biol Chem 280,40032-40 (2005).
    • (2005) J Biol Chem , vol.280 , pp. 40032-40040
    • Steenbergen, R.1
  • 48
    • 12344276290 scopus 로고    scopus 로고
    • Mitochondrial Ca21-activated K1channels in cardiac myocytes: A mechanism of the cardioprotective effect andmodulation by protein kinase A
    • Sato, T., Saito, T., Saegusa, N. & Nakaya, H. Mitochondrial Ca21-activated K1channels in cardiac myocytes: A mechanism of the cardioprotective effect andmodulation by protein kinase A. Circulation 111, 198-203 (2005).
    • (2005) Circulation , vol.111 , pp. 198-203
    • Sato, T.1    Saito, T.2    Saegusa, N.3    Nakaya, H.4
  • 49
    • 0036826892 scopus 로고    scopus 로고
    • Cytoprotective role of Ca21-activated K1 channels in the cardiacinner mitochondrial membrane
    • Xu, W. et al. Cytoprotective role of Ca21-activated K1 channels in the cardiacinner mitochondrial membrane. Science 298, 1029-33 (2002).
    • (2002) Science , vol.298 , pp. 1029-1033
    • Xu, W.1
  • 50
    • 8844283373 scopus 로고    scopus 로고
    • Intermittent high altitude hypoxia protects the heart against lethalCa21 overload injury
    • Xie, Y. et al. Intermittent high altitude hypoxia protects the heart against lethalCa21 overload injury. Life Sci 76, 559-72 (2004).
    • (2004) Life Sci , vol.76 , pp. 559-572
    • Xie, Y.1
  • 51
    • 79551501900 scopus 로고    scopus 로고
    • Mitochondrial BKCa channels contribute toprotection of cardiomyocytes isolated from chronically hypoxic rats
    • Borchert, G. H., Yang, C. & Kolar, F. Mitochondrial BKCa channels contribute toprotection of cardiomyocytes isolated from chronically hypoxic rats. Am J PhysiolHeart Circ Physiol 300, H507-13 (2011).
    • (2011) Am J PhysiolHeart Circ Physiol , vol.300
    • Borchert, G.H.1    Yang, C.2    Kolar, F.3
  • 52
    • 0037280842 scopus 로고    scopus 로고
    • Protection of rat pancreatic islets by potassium channel openersagainst alloxan, sodium nitroprusside and interleukin-1beta mediatedsuppression-possible involvement of the mitochondrial membrane potential
    • Kullin, M. et al. Protection of rat pancreatic islets by potassium channel openersagainst alloxan, sodium nitroprusside and interleukin-1beta mediatedsuppression-possible involvement of the mitochondrial membrane potential.Diabetologia 46, 80-8 (2003).
    • (2003) Diabetologia , vol.46 , pp. 80-88
    • Kullin, M.1
  • 53
    • 74049140420 scopus 로고    scopus 로고
    • K(ATP) channel openers protect mesencephalic neurons againstMPP1-induced cytotoxicity via inhibition of ROS production
    • Xie, J. et al. K(ATP) channel openers protect mesencephalic neurons againstMPP1-induced cytotoxicity via inhibition of ROS production. J Neurosci Res 88,428-37 (2010).
    • (2010) J Neurosci Res , vol.88 , pp. 428-437
    • Xie, J.1
  • 55
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy, M. P. How mitochondria produce reactive oxygen species. Biochem J417, 1-13 (2009).
    • (2009) Biochem J417 , pp. 1-13
    • Murphy, M.P.1
  • 57
    • 79960157303 scopus 로고    scopus 로고
    • Bax inhibitor 1, a modulator of calcium homeostasis,confers affective resilience
    • Hunsberger, J. G. et al. Bax inhibitor 1, a modulator of calcium homeostasis,confers affective resilience. Brain Res 1403, 19-27 (2011).
    • (2011) Brain Res , vol.1403 , pp. 19-27
    • Hunsberger, J.G.1
  • 58
    • 79960216863 scopus 로고    scopus 로고
    • Baxinhibitor-1: A highly conserved endoplasmic reticulum-resident cell deathsuppressor
    • Ishikawa, T., Watanabe, N., Nagano, M., Kawai-Yamada, M. & Lam, E. Baxinhibitor-1: a highly conserved endoplasmic reticulum-resident cell deathsuppressor. Cell Death Differ 18, 1271-8 (2011).
    • (2011) Cell Death Differ , vol.18 , pp. 1271-1278
    • Ishikawa, T.1    Watanabe, N.2    Nagano, M.3    Kawai-Yamada, M.4    Lam, E.5
  • 59
    • 79960134603 scopus 로고    scopus 로고
    • Enhanced lysosomal activity is involved in Bax inhibitor-1-induced regulation of the endoplasmic reticulum (ER) stress response and celldeath against ER stress: Involvement of vacuolar H1-ATPase (V-ATPase)
    • Lee, G. H. et al. Enhanced lysosomal activity is involved in Bax inhibitor-1-induced regulation of the endoplasmic reticulum (ER) stress response and celldeath against ER stress: involvement of vacuolar H1-ATPase (V-ATPase). J BiolChem 286, 24743-53 (2011).
    • (2011) J BiolChem , vol.286 , pp. 24743-24753
    • Lee, G.H.1
  • 60
    • 79956321772 scopus 로고    scopus 로고
    • Ca21signaling tools acquired from prostasomes are required forprogesterone-induced sperm motility
    • Park, K. H. et al. Ca21signaling tools acquired from prostasomes are required forprogesterone-induced sperm motility. Sci Signal 4, ra31 (2011).
    • (2011) Sci Signal , vol.4
    • Park, K.H.1
  • 61
    • 78649425814 scopus 로고    scopus 로고
    • PML regulates apoptosis at endoplasmic reticulum by modulatingcalcium release
    • Giorgi, C. et al. PML regulates apoptosis at endoplasmic reticulum by modulatingcalcium release. Science 330, 1247-51 (2010).
    • (2010) Science , vol.330 , pp. 1247-1251
    • Giorgi, C.1
  • 62
    • 77955708533 scopus 로고    scopus 로고
    • Ero1alpha requires oxidizing and normoxic conditions tolocalize to the mitochondria-associated membrane (MAM)
    • Gilady, S. Y. et al. Ero1alpha requires oxidizing and normoxic conditions tolocalize to the mitochondria-associated membrane (MAM). Cell StressChaperones 15, 619-29 (2010).
    • (2010) Cell StressChaperones , vol.15 , pp. 619-629
    • Gilady, S.Y.1
  • 63
    • 0035310832 scopus 로고    scopus 로고
    • Recombinant aequorin and green fluorescent protein as valuabletools in the study of cell signalling
    • Chiesa, A. et al. Recombinant aequorin and green fluorescent protein as valuabletools in the study of cell signalling. Biochem J 355, 1-12 (2001).
    • (2001) Biochem J , vol.355 , pp. 1-12
    • Chiesa, A.1
  • 64
    • 84870621600 scopus 로고    scopus 로고
    • MCUR1 is an essential component of mitochondrialCa21 uptake that regulates cellular metabolism
    • Mallilankaraman, K. et al. MCUR1 is an essential component of mitochondrialCa21 uptake that regulates cellular metabolism. Nat Cell Biol 14, 1336-43(2012).
    • (2012) Nat Cell Biol , vol.14 , pp. 1336-1343
    • Mallilankaraman, K.1
  • 65
    • 84868629814 scopus 로고    scopus 로고
    • CaMKII determines mitochondrial stress responses in heart
    • Joiner, M. L. et al. CaMKII determines mitochondrial stress responses in heart.Nature 491, 269-73 (2012).
    • (2012) Nature , vol.491 , pp. 269-273
    • Joiner, M.L.1
  • 66
    • 77955486657 scopus 로고    scopus 로고
    • Autophagy induction and CHOP under-expression promotessurvival of fibroblasts from rheumatoid arthritis patients under endoplasmicreticulum stress
    • Shin, Y. J. et al. Autophagy induction and CHOP under-expression promotessurvival of fibroblasts from rheumatoid arthritis patients under endoplasmicreticulum stress. Arthritis Res Ther 12, R19 (2010).
    • (2010) Arthritis Res Ther , vol.12
    • Shin, Y.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.