The relationships between clinical characteristics, alcohol and psychotropic exposure, and circadian gene expression in human postmortem samples of affective disorder and control subjects

Psychiatry Research

Volumn 218, Issue 3, 2014, Pages 359-362

  Gonzalez, Robert ^a   Bernardo, Carmina ^b   Cruz, Dianne ^c   Walss Bass, Consuelo ^c   Thompson, Peter M ^c  

^a Texas Tech University Health Sciences Center El Paso   (United States)

^b MAKATI MEDICAL CENTER   (Philippines)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Bipolar disorder; Circadian genes; Major depressive disorder

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; CRYPTOCHROME 1; CRYPTOCHROME 2; GLYCOGEN SYNTHASE KINASE 3BETA; MEMBRANE PROTEIN; MOOD STABILIZER; NEUROLEPTIC AGENT; PER1 PROTEIN; PER2 PROTEIN; PER3 PROTEIN; PROTEIN TIMELESS; PSYCHOTROPIC AGENT; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR BETA; UNCLASSIFIED DRUG; CIRCADIAN RHYTHM SIGNALING PROTEIN;

ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ALCOHOLISM; ANTERIOR CINGULATE; ARTICLE; BIPOLAR DISORDER; CIRCADIAN RHYTHM; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ETHNICITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INSOMNIA; MAJOR DEPRESSION; MOOD DISORDER; PREFRONTAL CORTEX; PRIORITY JOURNAL; ZONA INCERTA; AUTOPSY; BRAIN; CASE CONTROL STUDY; DRINKING BEHAVIOR; FEMALE; GENE EXPRESSION PROFILING; GENETICS; MALE; PATHOLOGY; POSTMORTEM CHANGE; REFERENCE VALUE;

ALCOHOL DRINKING; AUTOPSY; BIPOLAR DISORDER; BRAIN; CASE-CONTROL STUDIES; CIRCADIAN CLOCKS; CIRCADIAN RHYTHM; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MALE; MOOD DISORDERS; PERIOD CIRCADIAN PROTEINS; POSTMORTEM CHANGES; REFERENCE VALUES;

EID: 84902079038     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2014.04.048     Document Type: Article

References (45)

1. Archer S.N., Robilliard D.L., Skene D.J., Smits M., Williams A., Arendt J., von Schantz M. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 2003, 26(4):413-415.
2. Best J.D., Maywood E.S., Smith K.L., Hastings M.H. Rapid resetting of the mammalian circadian clock. Journal of Neuroscience 1999, 19(2):828-835.
3. Bowden C.L., Singh V., Thompson P., Gonzalez J.M., Katz M.M., Dahl M., Prihoda T.J., Chang X. Development of the bipolar inventory of symptoms scale. Acta Psychiatrica Scandinavica 2007, 116(3):189-194.
4. Buijs R.M., Kalsbeek A., van der Woude T.P., van Heerikhuize J.J., Shinn S. Suprachiasmatic nucleus lesion increases corticosterone secretion. American Journal of Physiology 1993, 264(6 Pt 2):R1186-1192.
5. Cheng M.Y., Bittman E.L., Hattar S., Zhou Q.Y. Regulation of prokineticin 2 expression by light and the circadian clock. BMC Neuroscience 2005, 6(1):17.
6. Cheng M.Y., Bullock C.M., Li C., Lee A.G., Bermak J.C., Belluzzi J., Weaver D.R., Leslie F.M., Zhou Q.Y. Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 2002, 417(6887):405-410.
7. Etain B., Milhiet V., Bellivier F., Leboyer M. Genetics of circadian rhythms and mood spectrum disorders. European Neuropsychopharmacology 2011, 21(Suppl. 4):S676-682.
8. Fagiolini A., Frank E., Scott J.A., Turkin S., Kupfer D.J. Metabolic syndrome in bipolar disorder: findings from the bipolar disorder center for Pennsylvanians. Bipolar Disorder 2005, 7(5):424-430.
9. Gekakis N., Staknis D., Nguyen H.B., Davis F.C., Wilsbacher L.D., King D.P., Takahashi J.S., Weitz C.J. Role of the CLOCK protein in the mammalian circadian mechanism. Science 1998, 280(5369):1564-1569.
10. Gould T.D., Manji H.K. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology 2005, 30(7):1223-1237.
11. Hamilton M. Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychology 1967, 6(4):278-296.
12. Hastings M., Maywood E.S. Circadian clocks in the mammalian brain. BioEssays 2000, 22(1):23-31.
13. Jin X., Shearman L.P., Weaver D.R., Zylka M.J., de Vries G.J., Reppert S.M. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 1999, 96(1):57-68.
14. Johansson A.S., Brask J., Owe-Larsson B., Hetta J., Lundkvist G.B. Valproic acid phase shifts the rhythmic expression of Period2::Luciferase. Journal of Biological Rhythms 2011, 26(6):541-551.
15. Jolkkonen J., Tuomisto L., van Wimersma Greidanus T.B., Riekkinen P.J. Vasopressin levels in the cerebrospinal fluid of rats with lesions of the paraventricular and suprachiasmatic nuclei. Neuroscience Letters 1988, 86(2):184-188.
16. Kornhauser J.M., Mayo K.E., Takahashi J.S. Light, immediate-early genes, and circadian rhythms. Behavior Genetics 1996, 26(3):221-240.
17. Kripke D.F., Nievergelt C.M., Joo E., Shekhtman T., Kelsoe J.R. Circadian polymorphisms associated with affective disorders. Journal of Circadian Rhythms 2009, 7:2.
18. Li J.Z., Bunney B.G., Meng F., Hagenauer M.H., Walsh D.M., Vawter M.P., Evans S.J., Choudary P.V., Cartagena P., Barchas J.D., Schatzberg A.F., Jones E.G., Myers R.M., Watson S.J., Akil H., Bunney W.E. Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. Proceedings of the National Acadamy of Science United States of America 2013, 110(24):9950-9955.
19. Marballi K., Cruz D., Thompson P., Walss-Bass C. Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings. PLoS One 2012, 7(5):e36431.
20. McIntyre R.S., Rasgon N.L., Kemp D.E., Nguyen H.T., Law C.W., Taylor V.H., Woldeyohannes H.O., Alsuwaidan M.T., Soczynska J.K., Kim B., Lourenco M.T., Kahn L.S., Goldstein B.I. Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap. Current Diabetes Reports 2009, 9(1):51-59.
21. Nievergelt C.M., Kripke D.F., Barrett T.B., Burg E., Remick R.A., Sadovnick A.D., McElroy S.L., Keck P.E., Schork N.J., Kelsoe J.R. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2006, 141B(3):234-241.
22. O'Brien W.T., Harper A.D., Jove F., Woodgett J.R., Maretto S., Piccolo S., Klein P.S. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. Journal of Neuroscience 2004, 24(30):6791-6798.
23. Osland T.M., Ferno J., Havik B., Heuch I., Ruoff P., Laerum O.D., Steen V.M. Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. Journal of Psychopharmacology 2011, 25(7):924-933.
24. Patel S.D., Le-Niculescu H., Koller D.L., Green S.D., Lahiri D.K., McMahon F.J., Nurnberger J.I., Niculescu A.B. Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2010, 153B(4):850-877.
25. Perreau-Lenz S., Spanagel R. The effects of drugs of abuse on clock genes. Drug News and Perspectives 2008, 21(4):211-217.
26. Pickard B.S., Christoforou A., Thomson P.A., Fawkes A., Evans K.L., Morris S.W., Porteous D.J., Blackwood D.H., Muir W.J. Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder. Molecular Psychiatry 2009, 14(9):874-884.
27. Ralph M.R., Foster R.G., Davis F.C., Menaker M. Transplanted suprachiasmatic nucleus determines circadian period. Science 1990, 247(4945):975-978.
28. Rosenwasser A.M. Alcohol, antidepressants, and circadian rhythms. Human and animal models. Alcohol Research and Health 2001, 25(2):126-135.
29. Rosenwasser A.M., Fecteau M.E., Logan R.W. Effects of ethanol intake and ethanol withdrawal on free-running circadian activity rhythms in rats. Physiology and Behavior 2005, 84(4):537-542.
30. Roybal K., Theobold D., Graham A., DiNieri J.A., Russo S.J., Krishnan V., Chakravarty S., Peevey J., Oehrlein N., Birnbaum S., Vitaterna M.H., Orsulak P., Takahashi J.S., Nestler E.J., Carlezon W.A., McClung C.A. Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Science United States of America. 2007, 104(15):6406-6411.
31. Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nature Protocols 2008, 3(6):1101-1108.
32. Serretti A., Benedetti F., Mandelli L., Lorenzi C., Pirovano A., Colombo C., Smeraldi E. Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2003, 121(1):35-38.
33. Sibille E., Morris H.M., Kota R.S., Lewis D.A. GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders. International Journal of Neuropsychopharmacology 2011, 14(6):721-734.
34. Soria V., Martinez-Amoros E., Escaramis G., Valero J., Perez-Egea R., Garcia C., Gutierrez-Zotes A., Puigdemont D., Bayes M., Crespo J.M., Martorell L., Vilella E., Labad A., Vallejo J., Perez V., Menchon J.M., Estivill X., Gratacos M., Urretavizcaya M. Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology 2010, 35(6):1279-1289.
35. Spanagel R., Rosenwasser A.M., Schumann G., Sarkar D.K. Alcohol consumption and the body[U+05F3]s biological clock. Alcohol: Clinical and Experimental Research 2005, 29(8):1550-1557.
36. Spencer S., Falcon E., Kumar J., Krishnan V., Mukherjee S., Birnbaum S.G., McClung C.A. Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. European Journal of Neuroscience 2013, 37(2):242-250.
37. Spurgeon S.L., Jones R.C., Ramakrishnan R. High throughput gene expression measurement with real time PCR in a microfluidic dynamic array. PLoS One 2008, 3(2):e1662.
38. Thompson P.M., Gillin J.C., Golshan S., Irwin M. Polygraphic sleep measures differentiate alcoholics and stimulant abusers during short-term abstinence. Biological Psychiatry 1995, 38(12):831-836.
39. Thompson P.M., Gonzalez J.M., Singh V., Schoolfield J.D., Katz M.M., Bowden C.L. Principal domains of behavioral psychopathology identified by the bipolar inventory of signs and symptoms scale (BISS). Psychiatry Research 2010, 175(3):221-226.
40. Toh K.L., Jones C.R., He Y., Eide E.J., Hinz W.A., Virshup D.M., Ptacek L.J., Fu Y.H. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science 2001, 291(5506):1040-1043.
41. Ueda H.R., Hayashi S., Chen W., Sano M., Machida M., Shigeyoshi Y., Iino M., Hashimoto S. System-level identification of transcriptional circuits underlying mammalian circadian clocks. Nature Genetics 2005, 37(2):187-192.
42. Vitaterna M.H., King D.P., Chang A.M., Kornhauser J.M., Lowrey P.L., McDonald J.D., Dove W.F., Pinto L.H., Turek F.W., Takahashi J.S. Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 1994, 264(5159):719-725.
43. Williams J.B. Standardizing the hamilton depression rating scale: past, present, and future. European Archives of Psychiatry and Clinical Neuroscience 2001, 251(Suppl 2):II6-12.
44. Young R.C., Biggs J.T., Ziegler V.E., Meyer D.A. A rating scale for mania: reliability, validity and sensitivity. British Journal of Psychiatry 1978, 133:429-435.
45. Zhou Q.Y., Cheng M.Y. Prokineticin 2 and circadian clock output. FEBS Journal 2005, 272(22):5703-5709.