Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP+

International Journal of Biological Macromolecules

Volumn 69, Issue , 2014, Pages 171-175

  Deng, Qi ^a   Yang, Xinling ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Gynostemma pentaphyllum; Neuroprotective activities; Polysaccharides

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CASPASE 3; CASPASE 9; CYTOCHROME C; GYNOSTEMMA PENTAPHYLLUM POLYSACCHARIDE; LACTATE DEHYDROGENASE; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; POLYSACCHARIDE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; METABOLIC INHIBITION; NEUROPROTECTION; PARKINSON DISEASE; PC12 CELL LINE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; ANIMAL; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GYNOSTEMMA; METABOLISM; NERVE CELL; RAT; SECRETION (PROCESS); TOXICITY;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL SURVIVAL; CYTOCHROMES C; GENE EXPRESSION REGULATION; GYNOSTEMMA; L-LACTATE DEHYDROGENASE; NEURONS; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; PC12 CELLS; POLY(ADP-RIBOSE) POLYMERASES; POLYSACCHARIDES; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

EID: 84901984259     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2014.05.049     Document Type: Article

References (28)

1. Braak H., Del Tredici K., Rub U., de Vos R.A., Jansen Steur E.N., Braak E. Neurobiol. Aging 2003, 24:197-211.
2. Lang A.E., Lozano A.M. N. Engl. J. Med. 1998, 339:1044-1053.
3. Schapira A.H. Mitochondria in the aetiology and pathogenesis of Parkinson' disease. Lancet Neurol. 2008, 7:97-109.
4. Chung V., Liu L., Bian Z., Zhao Z., Leuk Fong W., Kum W.F., Gao J., Li M. Mov. Disord. 2006, 21:1709-1715.
5. Li X.L., Cheng W.D., Li J., Guo X.L., Guo C.J., Meng X.H., Sun S.G., Wang L.X. Clin. Invest. Med. 2008, 31:258-264.
6. Levites Y., Weinreb O., Maor G., Youdim M.B., Mandel S. J. Neurochem. 2001, 78:1073-1082.
7. Van Kampen J., Robertson H., Hagg T., Drobitch R. Exp. Neurol. 2003, 184:521-529.
8. Houghton P.J., Howes M.J. Neurosignals 2005, 14:6-22.
9. Chen L.W., Wang Y.Q., Wei L.C., Shi M., Chan Y.S. CNS Neurol. Disord.: Drug Targets 2007, 6:273-281.
10. Hu L.H., Chen Z.L., Xie Y.Y. J. Nat. Prod. 1996, 59:1143-1145.
11. Circosta C., De Pasquale R., Occhiuto F. Phytomedicine 2005, 12:638-643.
12. Zhou H.H., Liang J.X., Hu W.H. J. Xiamen Univ. 2001, 40:990-993.
13. Rujjanawate C., Kanjanapothi D., Amornlerdpison D. Phytomedicine 2004, 11:431-435.
14. Qian X.H., Wang Y.X., Tang X.L. J. China Pharm. Univ. 1998, 30:51-53.
15. la Cour B., Mølgaard P., Yi Z. J. Ethnopharmacol. 1995, 46:125-129.
16. Wang P., Niu L., Guo X.D., Gao L., Li W.X., Jia D., Wang X.L., Ma L.T., Gao G.D. Brain Res. Bull. 2010, 83:266-271.
17. Choi H.S., Park M.S., Kim S.H., Hwang B.Y., Lee C.K., Lee M.K. Molecules 2010, 15:2814-2824.
18. Datki Z., Juhász A., Gálfi M., Soós K., Papp R., Zádori D., Penke B. Brain Res. Bull. 2003, 62:223-229.
19. Qi F., Li A., Zhao L., Xu H., Inagaki H., Wang D., Cui X., Gao B., Kokudo N., Nakata M., Tang W. J. Ethnopharmacol. 2010, 128:654-661.
20. Faff-Michalak L., Albrecht J. Mol. Chem. Neuropathol. 1993, 18:257-265.
21. Nunez G., Benedict M.A., Hu Y., Inohara N. Oncogene 1998, 17:3237-3245.
22. Grütter M.G. Curr. Opin. Struct. Biol. 2000, 10:649-655.
23. Cory S., Adams J.M. Nat. Rev. Cancer 2002, 2:647-656.
24. Nicotra A., Parvez S. Neurotoxicol. Teratol. 2002, 24:599-605.
25. O'Malley K.L., Liu J., Lotharius J., Holtz W. Neurobiol. Dis. 2003, 14:43-51.
26. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Nature 1994, 371:346-347.
27. Le D.A., Wu Y., Huang Z., Matsushita K., Plesnila N., Augustinack J.C., Hyman B.T., Yuan J., Kuida K., Flavell R.A., Moskowitz M.A. Proc. Nat. Acad. Sci. U.S. A. 2002, 99:15188-15193.
28. Kitamura Y., Kosaka T., Kakimura J.I., Matsuoka Y., Kohno Y., Nomura Y., Taniguchi T. Mol. Pharmacol. 1998, 54:1046-1054.