Protective effect of estrogen on apoptosis in a cell culture model of Parkinson's disease

Clinical and Investigative Medicine

Volumn 31, Issue 5, 2008, Pages

  Li, Xue Li ^a   Cheng, Wei Dong ^a   Li, Juan ^a   Guo, Xian Ling ^a   Guo, Cun Ju ^a   Meng, Xian Hui ^a   Sun, Sheng Gang ^b   Wang, Le Xin ^c  

^a LIAOCHENG PEOPLE'S HOSPITAL   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c CHARLES STURT UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ESTROGEN; INTERLEUKIN 1BETA; PROTEIN BCL X; TYROSINE 3 MONOOXYGENASE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; PARKINSON DISEASE; PRIORITY JOURNAL;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CASPASE 1; CELL SURVIVAL; ESTROGENS; HERBICIDES; MODELS, BIOLOGICAL; PARKINSON DISEASE; PC12 CELLS; RATS; TYROSINE 3-MONOOXYGENASE;

EID: 52949142726     PISSN: 0147958X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ramirez AD, Liu X, Menniti FS. Repeated Estradiol Treatment Prevents MPTP-Induced Dopamine Depletion in Male Mice. Neuroendocrinology 2003;77:223-31.
2. Gelinas S, Martinoli MG. Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells. J Neurosci Res 2002;70:90-6.
3. Horstink MW, Strijks E, Dluzen DE. Estrogen and Parkinson's disease. Adv Neurol 2003;91:107-14.
4. + Parkinson's disease model. Neuropharmacology 2002;42:1056-64.
5. Green L, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 1976;73:2424-8.
6. Timothy JS, William DA. Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: a model for neurotoxicological studies. Neurotoxicology 1991;12:473-92.
7. Yamamoto N, Sawada H, Izumi Y, et al. Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease. J Biological Chemistry 2007;282:4364-72.
8. Seegal RF, Brosch K, Bush B, Ritz M, Shain W. Effects of Aroclor 1254 on dopamine and norepinephrine concentrations in pheochromocytoma (PC-12) cells. Neurotoxicology 1989;10:757-64.
9. Shafer TJ, Atchison WD. Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: a model for neurotoxicological studies. Neurotoxicology 1991;12:473-92.
10. Nickals WJ, Heikkila RE. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenylpyridine: a metabolite of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin. Life Sci 1985;36:2503-8.
11. Tipton KF, Singer TP. Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J Neurochem 1993;61:1191-206.
12. Obata T. Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping. Toxicol Lett 2002;132:83-93.
13. Christis Chinopiulos, Vera Adam-Vizi. Mitochondria deficient in complex-I activity is depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease. J Neurochem 2001;76:302-6.
14. Ragonese P, D'Amelio M, Savettieri G. Implications for estrogens in Parkinson's disease: an epidemiological approach. Ann New York Acad Sci 2006;1089:373-82.
15. Nicoletti A, Arabia G, Pugliese P, et al. Hormonal replacement therapy in women with Parkinson disease and levodopa-induced dyskinesia: a crossover trial. Clin Neuropharmacol 2007;30:276-80.
16. Pau KY, Hess DL, Kohama S, Bao J, Pau CY, Spies HG. Oestrogen upregulates noradrenaline release in the mediobasal hypothalamus and tyrosine hydroxylase gene expression in the brainstem of ovariectomized rhesus macaques. J Neuroendocrinol 2000;12:899-909.
17. Ivanova T, Beyer C. Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain. J Neurobiol 2003;54:638-47.
18. Yanagihara N, Toyohira Y, Ueno S, et al. Stimulation of catecholamine synthesis by environmental estrogenic pollutants. Endocrinology 2005;146:265-72.
19. Tripanichkul W, Jaroensuppaperch EO, Finkelstein DI. Estrogen enhances the number of nigral dopaminergic neurons of adult male mice without affecting nigral neuroglial number and morphology. Neurosci Lett 2008;25:435:210-4.
20. Chan CR, Hsu JT, Chang IT, Young YC, Lin CM, Ying C. The effects of glutamate can be attenuated by estradiol via estrogen receptor dependent pathway in rat adrenal pheochromocytoma cells. Endocrine 2007;31:44-51.
21. Merot Y, Ferriere F, Debroas E, Flouriot G, Duval D, Saligaut C. Estrogen receptor alpha mediates neuronal differentiation and neuroprotection in PC12 cells: critical role of the A/B domain of the receptor. J Mol Endocrinol 2005;35:257-67.
22. Alexaki VI, Charalampopoulos I, Kampa M, et al. Estrogen exerts neuroprotective effects via membrane estrogen receptors and rapid Akt/NOS activation. FASEB J 2004;18:1594-6.