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Volumn 4, Issue , 2013, Pages 269-287

Exercise training and adverse cardiac remodeling and dysfunction in mice

Author keywords

Cardiac hypertrophy; Cardiac remodeling; eNOS deficiency; eNOS overexpression; Exercise training; Myocardial infarction; Pressure overload

Indexed keywords


EID: 84901951793     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-5203-4_14     Document Type: Chapter
Times cited : (1)

References (100)
  • 1
    • 1842579393 scopus 로고    scopus 로고
    • Hypertrophy of the heart: A new therapeutic target
    • Frey N, Katus HA, Olson EN, Hill JA (2004) Hypertrophy of the heart: a new therapeutic target? Circulation 109:1580-1589
    • (2004) Circulation , vol.109 , pp. 1580-1589
    • Frey, N.1    Katus, H.A.2    Olson, E.N.3    Hill, J.A.4
  • 2
    • 0016681078 scopus 로고
    • Wall stress and patterns of hypertrophy in the human left ventricle
    • Grossman W, Jones D, McLaurin LP (1975) Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 56:56-64
    • (1975) J Clin Invest , vol.56 , pp. 56-64
    • Grossman, W.1    Jones, D.2    McLaurin, L.P.3
  • 3
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7:589-600
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 5
    • 0036946741 scopus 로고    scopus 로고
    • Prevention and reversal of left ventricular remodeling: Summation
    • Konstam MA, Udelson JE, Sharpe N (2002) Prevention and reversal of left ventricular remodeling: summation. J Card Fail 8:S506-S511
    • (2002) J Card Fail , vol.8 , pp. S506-S511
    • Konstam, M.A.1    Udelson, J.E.2    Sharpe, N.3
  • 6
    • 33846966331 scopus 로고    scopus 로고
    • Differences between pathological and physiological cardiac hypertrophy: Novel therapeutic strategies to treat heart failure
    • McMullen JR, Jennings GL (2007) Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. Clin Exp Pharmacol Physiol 34:255-262
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 255-262
    • McMullen, J.R.1    Jennings, G.L.2
  • 7
    • 42549090747 scopus 로고    scopus 로고
    • Alterations in vasomotor control of coronary resistance vessels in remodelled myocardium of swine with a recent myocardial infarction
    • Duncker DJ, de Beer VJ, Merkus D (2008) Alterations in vasomotor control of coronary resistance vessels in remodelled myocardium of swine with a recent myocardial infarction. Med Biol Eng Comput 46:485-497
    • (2008) Med Biol Eng Comput , vol.46 , pp. 485-497
    • Duncker, D.J.1    de Beer, V.J.2    Merkus, D.3
  • 8
    • 0029091633 scopus 로고
    • Effect of exercise on coronary pressure-flow relationship in hypertrophied left ventricle
    • Duncker DJ, Zhang J, Pavek TJ, Crampton MJ, Bache RJ (1995) Effect of exercise on coronary pressure-flow relationship in hypertrophied left ventricle. Am J Physiol 269:H271- H281
    • (1995) Am J Physiol , vol.269 , pp. H271-H281
    • Duncker, D.J.1    Zhang, J.2    Pavek, T.J.3    Crampton, M.J.4    Bache, R.J.5
  • 10
    • 21644488539 scopus 로고    scopus 로고
    • Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction
    • van der Velden J, Merkus D, Klarenbeek BR et al (2004) Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction. Circ Res 95:e85-e95
    • (2004) Circ Res , vol.95 , pp. e85-e95
    • van der Velden, J.1    Merkus, D.2    Klarenbeek, B.R.3
  • 11
    • 39749142663 scopus 로고    scopus 로고
    • Sarcomeric dysfunction in heart failure
    • Hamdani N, Kooij V, van Dijk S et al (2008) Sarcomeric dysfunction in heart failure. Cardiovasc Res 77:649-658
    • (2008) Cardiovasc Res , vol.77 , pp. 649-658
    • Hamdani, N.1    Kooij, V.2    van Dijk, S.3
  • 12
    • 35748974863 scopus 로고    scopus 로고
    • Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function
    • Spinale FG (2007) Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol Rev 87:1285
    • (2007) Physiol Rev , vol.87 , pp. 1285
    • Spinale, F.G.1
  • 13
    • 0035793176 scopus 로고    scopus 로고
    • Exercise training in coronary artery disease and coronary vasomotion
    • Gielen S, Schuler G, Hambrecht R (2001) Exercise training in coronary artery disease and coronary vasomotion. Circulation 103:E1-E6
    • (2001) Circulation , vol.103 , pp. E1-E6
    • Gielen, S.1    Schuler, G.2    Hambrecht, R.3
  • 15
    • 0029055786 scopus 로고
    • Cellular adaptations of the myocardium to chronic exercise
    • Moore RL, Korzick DH (1995) Cellular adaptations of the myocardium to chronic exercise. Prog Cardiovasc Dis 37:371-396
    • (1995) Prog Cardiovasc Dis , vol.37 , pp. 371-396
    • Moore, R.L.1    Korzick, D.H.2
  • 17
    • 0038742067 scopus 로고    scopus 로고
    • Mechanisms of exercise training in patients with heart failure
    • You Fang Z, Marwick TH (2003) Mechanisms of exercise training in patients with heart failure. Am Heart J 145:904-911
    • (2003) Am Heart J , vol.145 , pp. 904-911
    • You Fang, Z.1    Marwick, T.H.2
  • 18
    • 0027406234 scopus 로고
    • Physical training improves skeletal muscle metabolism in patients with chronic heart failure
    • Adamopoulos S, Coats AJ, Brunotte F et al (1993) Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol 21:1101-1106
    • (1993) J Am Coll Cardiol , vol.21 , pp. 1101-1106
    • Adamopoulos, S.1    Coats, A.J.2    Brunotte, F.3
  • 19
    • 0027376136 scopus 로고
    • Long-term physical training and left ventricular remodeling after anterior myocardial infarction: Results of the exercise in anterior myocardial infarction (EAMI) trial
    • Giannuzzi P, Tavazzi L, Temporelli PL et al (1993) Long-term physical training and left ventricular remodeling after anterior myocardial infarction: results of the exercise in anterior myocardial infarction (EAMI) trial. EAMI study group. J Am Coll Cardiol 22:1821-1829
    • (1993) EAMI study group. J Am Coll Cardiol , vol.22 , pp. 1821-1829
    • Giannuzzi, P.1    Tavazzi, L.2    Temporelli, P.L.3
  • 20
    • 0030880962 scopus 로고    scopus 로고
    • Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: Results of the exercise in left ventricular dysfunction (ELVD) trial
    • Giannuzzi P, Temporelli PL, Corra U et al (1997) Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: results of the exercise in left ventricular dysfunction (ELVD) trial. Circulation 96:1790-1797
    • (1997) Circulation , vol.96 , pp. 1790-1797
    • Giannuzzi, P.1    Temporelli, P.L.2    Corra, U.3
  • 21
    • 0042074080 scopus 로고    scopus 로고
    • Antiremodeling effect of long-term exercise training in patients with stable chronic heart failure: Results of the exercise in left ventricular dysfunction and chronic heart failure (ELVD-CHF) trial
    • Giannuzzi P, Temporelli PL, Corra U, Tavazzi L (2003) Antiremodeling effect of long-term exercise training in patients with stable chronic heart failure: results of the exercise in left ventricular dysfunction and chronic heart failure (ELVD-CHF) trial. Circulation 108:554-559
    • (2003) Circulation , vol.108 , pp. 554-559
    • Giannuzzi, P.1    Temporelli, P.L.2    Corra, U.3    Tavazzi, L.4
  • 22
    • 34249981756 scopus 로고    scopus 로고
    • A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: The benefit depends on the type of training performed
    • Haykowsky MJ, Liang Y, Pechter D et al (2007) A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed. J Am Coll Cardiol 49:2329-2336
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2329-2336
    • Haykowsky, M.J.1    Liang, Y.2    Pechter, D.3
  • 23
    • 0023685232 scopus 로고
    • Exercise training after anterior Q wave myocardial infarction: Importance of regional left ventricular function and topography
    • Jugdutt BI, Michorowski BL, Kappagoda CT (1988) Exercise training after anterior Q wave myocardial infarction: importance of regional left ventricular function and topography. J Am Coll Cardiol 12:362-372
    • (1988) J Am Coll Cardiol , vol.12 , pp. 362-372
    • Jugdutt, B.I.1    Michorowski, B.L.2    Kappagoda, C.T.3
  • 24
    • 0021052452 scopus 로고
    • The effect of early exercise on myocardial infarct scar formation
    • Kloner RA, Kloner JA (1983) The effect of early exercise on myocardial infarct scar formation. Am Heart J 106:1009-1013
    • (1983) Am Heart J , vol.106 , pp. 1009-1013
    • Kloner, R.A.1    Kloner, J.A.2
  • 25
    • 0028140237 scopus 로고
    • Effect of endurance training early or late after coronary artery occlusion on left ventricular remodeling, hemodynamics, and survival in rats with chronic transmural myocardial infarction
    • Gaudron P, Hu K, Schamberger R et al (1994) Effect of endurance training early or late after coronary artery occlusion on left ventricular remodeling, hemodynamics, and survival in rats with chronic transmural myocardial infarction. Circulation 89:402-412
    • (1994) Circulation , vol.89 , pp. 402-412
    • Gaudron, P.1    Hu, K.2    Schamberger, R.3
  • 26
    • 0346156031 scopus 로고    scopus 로고
    • Exercise at ventilatory threshold aggravates left ventricular remodeling in patients with extensive anterior acute myocardial infarction
    • Kubo N, Ohmura N, Nakada I et al (2004) Exercise at ventilatory threshold aggravates left ventricular remodeling in patients with extensive anterior acute myocardial infarction. Am Heart J 147:113-120
    • (2004) Am Heart J , vol.147 , pp. 113-120
    • Kubo, N.1    Ohmura, N.2    Nakada, I.3
  • 27
    • 34547641000 scopus 로고    scopus 로고
    • Effects of excessive long-term exercise on cardiac function and myocyte remodeling in hypertensive heart failure rats
    • Schultz RL, Swallow JG, Waters RP et al (2007) Effects of excessive long-term exercise on cardiac function and myocyte remodeling in hypertensive heart failure rats. Hypertension 50:410-416
    • (2007) Hypertension , vol.50 , pp. 410-416
    • Schultz, R.L.1    Swallow, J.G.2    Waters, R.P.3
  • 28
    • 23944495053 scopus 로고    scopus 로고
    • A novel model of cryoinjury-induced myocardial infarction in the mouse: A comparison with coronary artery ligation
    • van den Bos EJ, Mees BM, de Waard MC, de Crom R, Duncker DJ (2005) A novel model of cryoinjury-induced myocardial infarction in the mouse: a comparison with coronary artery ligation. Am J Physiol Heart Circ Physiol 289:H1291-H1300
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H1291-H1300
    • van den Bos, E.J.1    Mees, B.M.2    de Waard, M.C.3    de Crom, R.4    Duncker, D.J.5
  • 29
    • 34247101627 scopus 로고    scopus 로고
    • Early exercise training normalizes myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction
    • de Waard MC, van der Velden J, Bito V, Ozdemir S et al (2007) Early exercise training normalizes myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction. Circ Res 100:1079-1088
    • (2007) Circ Res , vol.100 , pp. 1079-1088
    • de Waard, M.C.1    van der Velden, J.2    Bito, V.3    Ozdemir, S.4
  • 30
    • 66149101525 scopus 로고    scopus 로고
    • Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction
    • de Waard MC, van der Velden J, Boontje NM et al (2009) Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction. Am J Physiol Heart Circ Physiol 296:H1513-H1523
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , pp. H1513-H1523
    • de Waard, M.C.1    van der Velden, J.2    Boontje, N.M.3
  • 31
    • 77952639447 scopus 로고    scopus 로고
    • Beneficial effects of exercise training after myocardial infarction require full eNOS expression
    • de Waard MC, van Haperen R, Soullie T et al (2010) Beneficial effects of exercise training after myocardial infarction require full eNOS expression. J Mol Cell Cardiol 48:1041-1049
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 1041-1049
    • de Waard, M.C.1    van Haperen, R.2    Soullie, T.3
  • 32
    • 0025873338 scopus 로고
    • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
    • Rockman HA, Ross RS, Harris AN et al (1991) Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc Natl Acad Sci USA 88:8277-8281
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8277-8281
    • Rockman, H.A.1    Ross, R.S.2    Harris, A.N.3
  • 33
    • 79955649525 scopus 로고    scopus 로고
    • Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis
    • van Deel ED, de Boer M, Kuster DW et al (2011) Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis. J Mol Cell Cardiol 50:1017-1025
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 1017-1025
    • van Deel, E.D.1    de Boer, M.2    Kuster, D.W.3
  • 34
    • 0037711391 scopus 로고    scopus 로고
    • Exercise assessment of transgenic models of human cardiovascular disease
    • Bernstein D (2003) Exercise assessment of transgenic models of human cardiovascular disease. Physiol Genomics 13:217-226
    • (2003) Physiol Genomics , vol.13 , pp. 217-226
    • Bernstein, D.1
  • 35
    • 77949346018 scopus 로고    scopus 로고
    • Early exercise training after myocardial infarction prevents contractile but not electrical remodelling or hypertrophy
    • Bito V, de Waard MC, Biesmans L et al (2010) Early exercise training after myocardial infarction prevents contractile but not electrical remodelling or hypertrophy. Cardiovasc Res 86:72-81
    • (2010) Cardiovasc Res , vol.86 , pp. 72-81
    • Bito, V.1    de Waard, M.C.2    Biesmans, L.3
  • 36
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH (1994) Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res 74:349-353
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 37
    • 0037232585 scopus 로고    scopus 로고
    • Modulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): Lessons from genetically modified mice
    • Massion PB, Balligand JL (2003) Modulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice. J Physiol 546:63-75
    • (2003) J Physiol , vol.546 , pp. 63-75
    • Massion, P.B.1    Balligand, J.L.2
  • 38
    • 0032102292 scopus 로고    scopus 로고
    • Nitric oxide synthase modulates angiogenesis in response to tissue ischemia
    • Murohara T, Asahara T, Silver M (1998) et all. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101:2567-2578
    • (1998) J Clin Invest , vol.101 , pp. 2567-2578
    • Murohara, T.1    Asahara, T.2    Silver, M.3
  • 39
    • 0033082589 scopus 로고    scopus 로고
    • Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide
    • Kim NN, Villegas S, Summerour SR, Villarreal FJ (1999) Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide. J Mol Cell Cardiol 31:457-466
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 457-466
    • Kim, N.N.1    Villegas, S.2    Summerour, S.R.3    Villarreal, F.J.4
  • 40
    • 33750884859 scopus 로고    scopus 로고
    • Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide
    • Ritchie RH, Schiebinger RJ, LaPointe MC, Marsh JD (1998) Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide. Am J Physiol 1998(275):H1370-H1374
    • (1998) Am J Physiol , vol.1998 , Issue.275 , pp. H1370-H1374
    • Ritchie, R.H.1    Schiebinger, R.J.2    LaPointe, M.C.3    Marsh, J.D.4
  • 41
    • 0037447249 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice
    • Jones SP, Greer JJ, van Haperen R et al (2003) Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice. Proc Natl Acad Sci USA 100:4891-4896
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4891-4896
    • Jones, S.P.1    Greer, J.J.2    van Haperen, R.3
  • 42
    • 34547909936 scopus 로고    scopus 로고
    • Vasomotor control in mice overexpressing human endothelial nitric oxide synthase
    • van Deel ED, Merkus D, van Haperen R et al (2007) Vasomotor control in mice overexpressing human endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol 293:H1144-H1153
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H1144-H1153
    • van Deel, E.D.1    Merkus, D.2    van Haperen, R.3
  • 43
    • 2442678986 scopus 로고    scopus 로고
    • Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction
    • Janssens S, Pokreisz P, Schoonjans L et al (2004) Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circ Res 94:1256-1262
    • (2004) Circ Res , vol.94 , pp. 1256-1262
    • Janssens, S.1    Pokreisz, P.2    Schoonjans, L.3
  • 44
    • 36348964192 scopus 로고    scopus 로고
    • Preconditioning results in S- nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport
    • Sun J, Morgan M, Shen RF, Steenbergen C, Murphy E (2007) Preconditioning results in S- nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport. Circ Res 101:1155-1163
    • (2007) Circ Res , vol.101 , pp. 1155-1163
    • Sun, J.1    Morgan, M.2    Shen, R.F.3    Steenbergen, C.4    Murphy, E.5
  • 45
    • 33750905662 scopus 로고    scopus 로고
    • S-nitrosylation: NO-related redox signaling to protect against oxidative stress
    • Sun J, Steenbergen C, Murphy E (2006) S-nitrosylation: NO-related redox signaling to protect against oxidative stress. Antioxid Redox Signal 8:1693-1705
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1693-1705
    • Sun, J.1    Steenbergen, C.2    Murphy, E.3
  • 46
    • 0033801011 scopus 로고    scopus 로고
    • Effects of ACE inhibitor, AT1 antagonist, and combined treatment in mice with heart failure
    • Cavasin MA, Yang XP, Liu YH et al (2000) Effects of ACE inhibitor, AT1 antagonist, and combined treatment in mice with heart failure. J Cardiovasc Pharmacol 36:472-480
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 472-480
    • Cavasin, M.A.1    Yang, X.P.2    Liu, Y.H.3
  • 47
    • 0035849576 scopus 로고    scopus 로고
    • Dysfunctional regulation of endothelial nitric oxide synthase (eNOS) expression in response to exercise in mice lacking one eNOS gene
    • Kojda G, Cheng YC, Burchfield J, Harrison DG (2001) Dysfunctional regulation of endothelial nitric oxide synthase (eNOS) expression in response to exercise in mice lacking one eNOS gene. Circulation 103:2839-2844
    • (2001) Circulation , vol.103 , pp. 2839-2844
    • Kojda, G.1    Cheng, Y.C.2    Burchfield, J.3    Harrison, D.G.4
  • 48
    • 0032897665 scopus 로고    scopus 로고
    • Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: Contributions of NOS isoforms to blood pressure and heart rate control
    • Kojda G, Laursen JB, Ramasamy S et al (1999) Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart rate control. Cardiovasc Res 42:206-213
    • (1999) Cardiovasc Res , vol.42 , pp. 206-213
    • Kojda, G.1    Laursen, J.B.2    Ramasamy, S.3
  • 49
    • 0035845630 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase limits left ventricular remodeling after myocardial infarction in mice
    • Scherrer-Crosbie M, Ullrich R, Bloch KD et al (2001) Endothelial nitric oxide synthase limits left ventricular remodeling after myocardial infarction in mice. Circulation 104:1286-1291
    • (2001) Circulation , vol.104 , pp. 1286-1291
    • Scherrer-Crosbie, M.1    Ullrich, R.2    Bloch, K.D.3
  • 50
    • 0036175376 scopus 로고    scopus 로고
    • Effect of ACE inhibitors and angiotensin II type 1 receptor antagonists on endothelial NO synthase knockout mice with heart failure
    • Liu YH, Xu J, Yang XP et al (2002) Effect of ACE inhibitors and angiotensin II type 1 receptor antagonists on endothelial NO synthase knockout mice with heart failure. Hypertension 39:375-381
    • (2002) Hypertension , vol.39 , pp. 375-381
    • Liu, Y.H.1    Xu, J.2    Yang, X.P.3
  • 51
    • 0345310069 scopus 로고    scopus 로고
    • Coronary hemodynamics in endothelial NO synthase knockout mice
    • Godecke A, Decking UK, Ding Z et al (1998) Coronary hemodynamics in endothelial NO synthase knockout mice. Circ Res 82:186-194
    • (1998) Circ Res , vol.82 , pp. 186-194
    • Godecke, A.1    Decking, U.K.2    Ding, Z.3
  • 52
    • 0036081648 scopus 로고    scopus 로고
    • Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice
    • Huang A, Sun D, Shesely EG et al (2002) Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice. Am J Physiol Heart Circ Physiol 282:H429- H436
    • (2002) Am J Physiol Heart Circ Physiol , vol.282 , pp. H429-H436
    • Huang, A.1    Sun, D.2    Shesely, E.G.3
  • 53
    • 0033679780 scopus 로고    scopus 로고
    • Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice
    • Lamping KG, Nuno DW, Shesely EG, Maeda N, Faraci FM (2000) Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice. Am J Physiol Heart Circ Physiol 279:H1906-H1912
    • (2000) Am J Physiol Heart Circ Physiol , vol.279 , pp. H1906-H1912
    • Lamping, K.G.1    Nuno, D.W.2    Shesely, E.G.3    Maeda, N.4    Faraci, F.M.5
  • 54
    • 33750730317 scopus 로고    scopus 로고
    • ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms
    • Meng W, Ma J, Ayata C et al (1996) ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. Am J Physiol 271:H1145-H1150
    • (1996) Am J Physiol , vol.271 , pp. H1145-H1150
    • Meng, W.1    Ma, J.2    Ayata, C.3
  • 56
    • 34250843129 scopus 로고    scopus 로고
    • Exercise-induced activation of cardiac sympathetic nerve triggers cardioprotection via redox-sensitive activation of eNOS and upregulation of iNOS
    • Akita Y, Otani H, Matsuhisa S et al (2007) Exercise-induced activation of cardiac sympathetic nerve triggers cardioprotection via redox-sensitive activation of eNOS and upregulation of iNOS. Am J Physiol Heart Circ Physiol 292:H2051-H2059
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H2051-H2059
    • Akita, Y.1    Otani, H.2    Matsuhisa, S.3
  • 57
    • 0141648341 scopus 로고    scopus 로고
    • Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice
    • van Haperen R, Cheng C, Mees BM et al (2003) Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice. Am J Pathol 163:1677-1686
    • (2003) Am J Pathol , vol.163 , pp. 1677-1686
    • van Haperen, R.1    Cheng, C.2    Mees, B.M.3
  • 58
    • 84857561592 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase of the bone marrow regulates myocardial hypertrophy, fibrosis, and angiogenesis
    • Kazakov A, Muller P, Jagoda P et al (2012) Endothelial nitric oxide synthase of the bone marrow regulates myocardial hypertrophy, fibrosis, and angiogenesis. Cardiovasc Res 93:397-405
    • (2012) Cardiovasc Res , vol.93 , pp. 397-405
    • Kazakov, A.1    Muller, P.2    Jagoda, P.3
  • 59
    • 84857539523 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase and cardiac remodelling: Location, location, location
    • Duncker DJ, van Deel ED (2012) Endothelial nitric oxide synthase and cardiac remodelling: location, location, location? Cardiovasc Res 93:383-385
    • (2012) Cardiovasc Res , vol.93 , pp. 383-385
    • Duncker, D.J.1    van Deel, E.D.2
  • 60
    • 48049117781 scopus 로고    scopus 로고
    • Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis
    • Werner C, Hanhoun M, Widmann T et al (2008) Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis. J Am Coll Cardiol 52:470-482
    • (2008) J Am Coll Cardiol , vol.52 , pp. 470-482
    • Werner, C.1    Hanhoun, M.2    Widmann, T.3
  • 61
    • 4744373765 scopus 로고    scopus 로고
    • Physical activity and cardiovascular disease
    • Wannamethee SG, Shaper AG (2002) Physical activity and cardiovascular disease. Semin Vasc Med 2:257-266
    • (2002) Semin Vasc Med , vol.2 , pp. 257-266
    • Wannamethee, S.G.1    Shaper, A.G.2
  • 62
    • 45549108083 scopus 로고    scopus 로고
    • Reduced physical activity and risk of chronic disease: The biology behind the consequences
    • Booth FW, Laye MJ, Lees SJ, Rector RS, Thyfault JP (2008) Reduced physical activity and risk of chronic disease: the biology behind the consequences. Eur J Appl Physiol 102:381-390
    • (2008) Eur J Appl Physiol , vol.102 , pp. 381-390
    • Booth, F.W.1    Laye, M.J.2    Lees, S.J.3    Rector, R.S.4    Thyfault, J.P.5
  • 63
    • 0032495586 scopus 로고    scopus 로고
    • Effects of walking on mortality among nonsmoking retired men
    • Hakim AA, Petrovitch H, Burchfiel CM et al (1998) Effects of walking on mortality among nonsmoking retired men. N Engl J Med 338:94-99
    • (1998) N Engl J Med , vol.338 , pp. 94-99
    • Hakim, A.A.1    Petrovitch, H.2    Burchfiel, C.M.3
  • 64
    • 18644385210 scopus 로고    scopus 로고
    • Walking compared with vigorous exercise for the prevention of cardiovascular events in women
    • Manson JE, Greenland P, LaCroix AZ et al (2002) Walking compared with vigorous exercise for the prevention of cardiovascular events in women. N Engl J Med 347:716-725
    • (2002) N Engl J Med , vol.347 , pp. 716-725
    • Manson, J.E.1    Greenland, P.2    LaCroix, A.Z.3
  • 65
    • 34247621859 scopus 로고    scopus 로고
    • Exercise and acute cardiovascular events placing the risks into perspective: A scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism and the Council on Clinical Cardiology
    • Thompson PD, Franklin BA, Balady GJ et al (2007) Exercise and acute cardiovascular events placing the risks into perspective: a scientific statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism and the Council on Clinical Cardiology. Circulation 115:2358-2368
    • (2007) Circulation , vol.115 , pp. 2358-2368
    • Thompson, P.D.1    Franklin, B.A.2    Balady, G.J.3
  • 66
    • 0022527323 scopus 로고
    • Improvement of left ventricular contractile function by exercise training in patients with coronary artery disease
    • Ehsani AA, Biello DR, Schultz J, Sobel BE, Holloszy JO (1986) Improvement of left ventricular contractile function by exercise training in patients with coronary artery disease. Circulation 74:350-358
    • (1986) Circulation , vol.74 , pp. 350-358
    • Ehsani, A.A.1    Biello, D.R.2    Schultz, J.3    Sobel, B.E.4    Holloszy, J.O.5
  • 67
    • 0037347967 scopus 로고    scopus 로고
    • Improvement of left ventricular dysfunction during exercise by walking in patients with successful percutaneous coronary intervention for acute myocardial infarction
    • Koizumi T, Miyazaki A, Komiyama N et al (2003) Improvement of left ventricular dysfunction during exercise by walking in patients with successful percutaneous coronary intervention for acute myocardial infarction. Circ J 67:233-237
    • (2003) Circ J , vol.67 , pp. 233-237
    • Koizumi, T.1    Miyazaki, A.2    Komiyama, N.3
  • 68
    • 0027446425 scopus 로고
    • Myocardial hypertrophy in the ischemic zone induced by exercise in rats after coronary reperfusion
    • Oh BH, Ono S, Rockman HA, Ross J Jr (1993) Myocardial hypertrophy in the ischemic zone induced by exercise in rats after coronary reperfusion. Circulation 87:598-607
    • (1993) Circulation , vol.87 , pp. 598-607
    • Oh, B.H.1    Ono, S.2    Rockman, H.A.3    Ross, J.4
  • 70
    • 0036217327 scopus 로고    scopus 로고
    • Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2 + sensitivity and SERCA-2 in rat after myocardial infarction
    • Wisloff U, Loennechen JP, Currie S, Smith GL, Ellingsen O (2002) Aerobic exercise reduces cardiomyocyte hypertrophy and increases contractility, Ca2 + sensitivity and SERCA-2 in rat after myocardial infarction. Cardiovasc Res 54:162-174
    • (2002) Cardiovasc Res , vol.54 , pp. 162-174
    • Wisloff, U.1    Loennechen, J.P.2    Currie, S.3    Smith, G.L.4    Ellingsen, O.5
  • 71
    • 0034494127 scopus 로고    scopus 로고
    • Sprint training restores normal contractility in postinfarction rat myocytes
    • Zhang LQ, Zhang XQ, Musch TI, Moore RL, Cheung JY (2000) Sprint training restores normal contractility in postinfarction rat myocytes. J Appl Physiol 89:1099-1105
    • (2000) J Appl Physiol , vol.89 , pp. 1099-1105
    • Zhang, L.Q.1    Zhang, X.Q.2    Musch, T.I.3    Moore, R.L.4    Cheung, J.Y.5
  • 72
    • 0024335652 scopus 로고
    • An overview of randomized trials of rehabilitation with exercise after myocardial infarction
    • O'Connor GT, Buring JE, Yusuf S et al (1989) An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation 80:234-244
    • (1989) Circulation , vol.80 , pp. 234-244
    • O'Connor, G.T.1    Buring, J.E.2    Yusuf, S.3
  • 73
    • 2342589486 scopus 로고    scopus 로고
    • Exercise-based rehabilitation for patients with coronary heart disease: Systematic review and meta-analysis of randomized controlled trials
    • Taylor RS, Brown A, Ebrahim S et al (2004) Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. Am J Med 116:682-692
    • (2004) Am J Med , vol.116 , pp. 682-692
    • Taylor, R.S.1    Brown, A.2    Ebrahim, S.3
  • 74
    • 0031794194 scopus 로고    scopus 로고
    • Exercise training improves myocardial tolerance to in vivo ischemia-reperfusion in the rat
    • Powers SK, Demirel HA, Vincent HK et al (1998) Exercise training improves myocardial tolerance to in vivo ischemia-reperfusion in the rat. Am J Physiol 275:R1468
    • (1998) Am J Physiol , vol.275 , pp. R1468
    • Powers, S.K.1    Demirel, H.A.2    Vincent, H.K.3
  • 75
    • 0033532699 scopus 로고    scopus 로고
    • Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation
    • Yamashita N, Hoshida S, Otsu K et al (1999) Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation. J Exp Med 189:1699-1706
    • (1999) J Exp Med , vol.189 , pp. 1699-1706
    • Yamashita, N.1    Hoshida, S.2    Otsu, K.3
  • 76
    • 0345708299 scopus 로고    scopus 로고
    • Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart
    • Brown DA, Jew KN, Sparagna GC, Musch TI, Moore RL (2003) Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart. J Appl Physiol 95:2510-2518
    • (2003) J Appl Physiol , vol.95 , pp. 2510-2518
    • Brown, D.A.1    Jew, K.N.2    Sparagna, G.C.3    Musch, T.I.4    Moore, R.L.5
  • 77
    • 34547121683 scopus 로고    scopus 로고
    • Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism
    • Zhang KR, Liu HT, Zhang HF et al (2007) Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism. Apoptosis 12:1579-1588
    • (2007) Apoptosis , vol.12 , pp. 1579-1588
    • Zhang, K.R.1    Liu, H.T.2    Zhang, H.F.3
  • 78
    • 0036023631 scopus 로고    scopus 로고
    • Exercise induces early and late myocardial preconditioning in dogs
    • Domenech R, Macho P, Schwarze H, Sanchez G (2002) Exercise induces early and late myocardial preconditioning in dogs. Cardiovasc Res 55:561-566
    • (2002) Cardiovasc Res , vol.55 , pp. 561-566
    • Domenech, R.1    Macho, P.2    Schwarze, H.3    Sanchez, G.4
  • 79
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124-1136
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 80
    • 0031890756 scopus 로고    scopus 로고
    • Hypothermia extends the cardioprotection by ischaemic preconditioning to coronary artery occlusions of longer duration
    • van den Doel MA, Gho BC, Duval SY et al (1998) Hypothermia extends the cardioprotection by ischaemic preconditioning to coronary artery occlusions of longer duration. Cardiovasc Res 37:76-82
    • (1998) Cardiovasc Res , vol.37 , pp. 76-82
    • van den Doel, M.A.1    Gho, B.C.2    Duval, S.Y.3
  • 81
    • 0017815123 scopus 로고
    • Exercise-induced reduction in myocardial infarct size after coronary artery occlusion in the rat
    • McElroy CL, Gissen SA, Fishbein MC (1978) Exercise-induced reduction in myocardial infarct size after coronary artery occlusion in the rat. Circulation 57:958-962
    • (1978) Circulation , vol.57 , pp. 958-962
    • McElroy, C.L.1    Gissen, S.A.2    Fishbein, M.C.3
  • 83
    • 50449111231 scopus 로고    scopus 로고
    • Regulation of coronary blood flow during exercise
    • Duncker DJ, Bache RJ (2008) Regulation of coronary blood flow during exercise. Physiol Rev 88:1009-1086
    • (2008) Physiol Rev , vol.88 , pp. 1009-1086
    • Duncker, D.J.1    Bache, R.J.2
  • 84
    • 69749126039 scopus 로고    scopus 로고
    • Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction
    • de Waard MC, Duncker DJ (2009) Prior exercise improves survival, infarct healing, and left ventricular function after myocardial infarction. J Appl Physiol 107:928-936
    • (2009) J Appl Physiol , vol.107 , pp. 928-936
    • de Waard, M.C.1    Duncker, D.J.2
  • 85
    • 0017294079 scopus 로고
    • Heart functional responses to pressure overload in exercised and sedentary rats
    • Dowell RT, Cutilletta AF, Rudnik MA, Sodt PC (1976) Heart functional responses to pressure overload in exercised and sedentary rats. Am J Physiol 230:199-204
    • (1976) Am J Physiol , vol.230 , pp. 199-204
    • Dowell, R.T.1    Cutilletta, A.F.2    Rudnik, M.A.3    Sodt, P.C.4
  • 86
    • 67649644862 scopus 로고    scopus 로고
    • Mechanisms by which exercise training benefits patients with heart failure
    • Crimi E, Ignarro LJ, Cacciatore F, Napoli C (2009) Mechanisms by which exercise training benefits patients with heart failure. Nat Rev Cardiol 6:292-300
    • (2009) Nat Rev Cardiol , vol.6 , pp. 292-300
    • Crimi, E.1    Ignarro, L.J.2    Cacciatore, F.3    Napoli, C.4
  • 87
    • 40849139513 scopus 로고    scopus 로고
    • Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats
    • Chicco AJ, McCune SA, Emter CA et al (2008) Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats. Hypertension 51:1096-1102
    • (2008) Hypertension , vol.51 , pp. 1096-1102
    • Chicco, A.J.1    McCune, S.A.2    Emter, C.A.3
  • 88
    • 21544448585 scopus 로고    scopus 로고
    • Improved myocardial beta-adrenergic responsiveness and signaling with exercise training in hypertension
    • MacDonnell SM, Kubo H, Crabbe DL et al (2005) Improved myocardial beta-adrenergic responsiveness and signaling with exercise training in hypertension. Circulation 111:3420-3428
    • (2005) Circulation , vol.111 , pp. 3420-3428
    • MacDonnell, S.M.1    Kubo, H.2    Crabbe, D.L.3
  • 89
    • 64849096300 scopus 로고    scopus 로고
    • Exercise training alters left ventricular geometry and attenuates heart failure in dahl salt-sensitive hypertensive rats
    • Miyachi M, Yazawa H, Furukawa M et al (2009) Exercise training alters left ventricular geometry and attenuates heart failure in dahl salt-sensitive hypertensive rats. Hypertension 53:701-707
    • (2009) Hypertension , vol.53 , pp. 701-707
    • Miyachi, M.1    Yazawa, H.2    Furukawa, M.3
  • 90
    • 67449096041 scopus 로고    scopus 로고
    • Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: The LIFE study
    • Boman K, Gerdts E, Wachtell K et al (2009) Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study. Eur J Cardiovasc Prev Rehabil 16:242-248
    • (2009) Eur J Cardiovasc Prev Rehabil , vol.16 , pp. 242-248
    • Boman, K.1    Gerdts, E.2    Wachtell, K.3
  • 91
    • 58649092842 scopus 로고    scopus 로고
    • Regular physical activity prevents development of left ventricular hypertrophy in hypertension
    • Palatini P, Visentin P, Dorigatti F et al (2009) Regular physical activity prevents development of left ventricular hypertrophy in hypertension. Eur Heart J 30:225-232
    • (2009) Eur Heart J , vol.30 , pp. 225-232
    • Palatini, P.1    Visentin, P.2    Dorigatti, F.3
  • 93
    • 17144419297 scopus 로고    scopus 로고
    • Aortic stenosis
    • Chambers J (2005) Aortic stenosis. BMJ 330:801-802
    • (2005) BMJ , vol.330 , pp. 801-802
    • Chambers, J.1
  • 94
    • 33645417788 scopus 로고    scopus 로고
    • Bicuspid aortic valve: Evaluation of the ability to participate in competitive sports: Case reports of two soccer players
    • Scharhag J, Meyer T, Kindermann I et al (2006) Bicuspid aortic valve: evaluation of the ability to participate in competitive sports: case reports of two soccer players. Clin Res Cardiol 95:228-234
    • (2006) Clin Res Cardiol , vol.95 , pp. 228-234
    • Scharhag, J.1    Meyer, T.2    Kindermann, I.3
  • 95
    • 33646441475 scopus 로고    scopus 로고
    • Bicuspid aortic valve: An innocent finding or a potentially life-threatening anomaly whose complications may be elicited by sports activity
    • Zeppilli P, Bianco M, Bria S, Palmieri V (2006) Bicuspid aortic valve: an innocent finding or a potentially life-threatening anomaly whose complications may be elicited by sports activity? J Cardiovasc Med (Hagerstown) 7:282-287
    • (2006) J Cardiovasc Med (Hagerstown) , vol.7 , pp. 282-287
    • Zeppilli, P.1    Bianco, M.2    Bria, S.3    Palmieri, V.4
  • 96
    • 0014114746 scopus 로고
    • Influence of hypertension on the hemodynamic response to exercise
    • Amery A, Julius S, Whitlock LS, Conway J (1967) Influence of hypertension on the hemodynamic response to exercise. Circulation 36:231-237
    • (1967) Circulation , vol.36 , pp. 231-237
    • Amery, A.1    Julius, S.2    Whitlock, L.S.3    Conway, J.4
  • 97
    • 33645282296 scopus 로고    scopus 로고
    • Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy
    • Konhilas JP, Watson PA, Maass A et al (2006) Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res 98:540-548
    • (2006) Circ Res , vol.98 , pp. 540-548
    • Konhilas, J.P.1    Watson, P.A.2    Maass, A.3
  • 98
    • 64849083165 scopus 로고    scopus 로고
    • Endurance training in the spontaneously hypertensive rat: Conversion of pathological into physiological cardiac hypertrophy
    • Garciarena CD, Pinilla OA, Nolly MB et al (2009) Endurance training in the spontaneously hypertensive rat: conversion of pathological into physiological cardiac hypertrophy. Hypertension 53:708-714
    • (2009) Hypertension , vol.53 , pp. 708-714
    • Garciarena, C.D.1    Pinilla, O.A.2    Nolly, M.B.3
  • 99
    • 37249033853 scopus 로고    scopus 로고
    • Central adaptations to exercise training in patients with chronic heart failure
    • Mezzani A, Corra U, Giannuzzi P (2008) Central adaptations to exercise training in patients with chronic heart failure. Heart Fail Rev 13:13-20
    • (2008) Heart Fail Rev , vol.13 , pp. 13-20
    • Mezzani, A.1    Corra, U.2    Giannuzzi, P.3
  • 100
    • 79953260009 scopus 로고    scopus 로고
    • A meta-analysis of the effects of exercise training on left ventricular remodeling following myocardial infarction: Start early and go longer for greatest exercise benefits on remodeling
    • Haykowsky M, Scott J, Esch B et al (2011) A meta-analysis of the effects of exercise training on left ventricular remodeling following myocardial infarction: start early and go longer for greatest exercise benefits on remodeling. Trials 12:92
    • (2011) Trials , vol.12 , pp. 92
    • Haykowsky, M.1    Scott, J.2    Esch, B.3


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