Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

Molecular Cell

Volumn 54, Issue 5, 2014, Pages 751-765

  Mathys, Hansruedi ^a,b   Basquin, JérÔme ^c   Ozgur, Sevim ^c   Czarnocki Cieciura, Mariusz ^d,e,f   Bonneau, Fabien ^c   Aartse, Aafke ^a   Dziembowski, Andrzej ^d,e   Nowotny, Marcin ^f   Conti, Elena ^c   Filipowicz, Witold ^a,b  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^e UNIVERSITY OF WARSAW   (Poland)

^f INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BINDING PROTEIN; CHEMOKINE RECEPTOR CCR4; CNOT1 PROTEIN; CNOT9 PROTEIN; DDX6 ADENOSINE TRIPHOSPHATASE; DEAD BOX PROTEIN; INITIATION FACTOR 4A; MESSENGER RNA; MICRORNA; PHOSPHOPROTEIN PHOSPHATASE 2A; POLYADENYLIC ACID; SCAFFOLD PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; GENE REPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; REPORTER GENE; RNA STABILITY; RNA TRANSLATION; STEREOCHEMISTRY; TRANSLATION REGULATION;

AMINO ACID SUBSTITUTION; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DEAD-BOX RNA HELICASES; HEK293 CELLS; HUMANS; MICRORNAS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

EID: 84901940130     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.03.036     Document Type: Article

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