Preexisting cerebral microbleeds on susceptibility-weighted magnetic resonance imaging and post-thrombolysis bleeding risk in 392 patients

Stroke

Volumn 45, Issue 6, 2014, Pages 1684-1688

  Gratz, Pascal P ^a   El Koussy, Marwan ^a   Hsieh, Kety ^a   Von Arx, Sebastian ^a   Mono, Marie Luise ^a   Heldner, Mirjam Rachel ^a   Fischer, Urs ^a   Mattle, Heinrich P ^a   Zubler, Christoph ^a   Schroth, Gerhard ^a   Gralla, Jan ^a   Arnold, Marcel ^a   Jung, Simon ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

mechanical thrombolysis; outcome assessment

Indexed keywords

ALTEPLASE; UROKINASE;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; FEMALE; HUMAN; INTRAVENOUS THROMBOLYSIS; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE SCANNER; OUTCOME ASSESSMENT; PREMEDICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SUSCEPTIBILITY WEIGHTED IMAGING;

MECHANICAL THROMBOLYSIS; OUTCOME ASSESSMENT;

AGED; AGED, 80 AND OVER; CEREBRAL ANGIOGRAPHY; CEREBRAL HEMORRHAGE; FEMALE; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; STROKE; THROMBOLYTIC THERAPY;

EID: 84901925344     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.004796     Document Type: Article

References (25)

1. Mullen MT, Pisapia JM, Tilwa S, Messé SR, Stein SC. Systematic review of outcome after ischemic stroke due to anterior circulation occlusion treated with intravenous, intra-arterial, or combined intravenous+intra-arterial thrombolysis. Stroke. 2012;43:2350-2355.
2. Fazekas F, Kleinert R, Roob G, Kleinert G, Kapeller P, Schmidt R, et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds. Am J Neuroradiol. 1999;20:637-642.
3. Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi Salman R, Warach S, et al; Microbleed Study Group. Cerebral micro-bleeds: a guide to detection and interpretation. Lancet Neurol. 2009;8:165-174.
4. Fiehler J, Albers GW, Boulanger JM, Derex L, Gass A, Hjort N, et al; MR STROKE Group. Bleeding risk analysis in stroke imaging before thromboLysis (BRASIL): pooled analysis of T2*-weighted magnetic resonance imaging data from 570 patients. Stroke. 2007;38:2738-2744.
5. Kidwell CS, Saver JL, Villablanca JP, Duckwiler G, Fredieu A, Gough K, et al. Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke. 2002;33:95-98.
6. Kakuda W, Thijs VN, Lansberg MG, Bammer R, Wechsler L, Kemp S, et al; DEFUSE Investigators. Clinical importance of microbleeds in patients receiving IV thrombolysis. Neurology. 2005;65:1175-1178.
7. Kim HS, Lee DH, Ryu CW, Lee JH, Choi CG, Kim SJ, et al. Multiple cerebral microbleeds in hyperacute ischemic stroke: impact on prevalence and severity of early hemorrhagic transformation after throm-bolytic treatment. Am J Roentgenol. 2006;186:1443-1449.
8. Derex L, Nighoghossian N, Hermier M, Adeleine P, Philippeau F, Honnorat J, et al. Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI. Cerebrovasc Dis. 2004;17:238-241.
9. Charidimou A, Kakar P, Fox Z, Werring DJ. Cerebral microbleeds and the risk of intracerebral haemorrhage after thrombolysis for acute isch-aemic stroke: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2013;84:277-280.
10. Shoamanesh A, Kwok CS, Lim PA, Benavente OR. Postthrombolysis intracranial hemorrhage risk of cerebral microbleeds in acute stroke patients: a systematic review and meta-analysis. Int J Stroke. 2013;8:348-356.
11. Knudsen KA, Rosand J, Karluk D, Greenberg SM. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology. 2001;56:537-539.
12. Cordonnier C, Al-Shahi Salman R, Wardlaw J. Spontaneous brain micro-bleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain. 2007;130(pt 8):1988-2003.
13. Nandigam RN, Viswanathan A, Delgado P, Skehan ME, Smith EE, Rosand J, et al. MR imaging detection of cerebral microbleeds: effect of susceptibility- weighted imaging, section thickness, and feld strength. Am J Neuroradiol. 2009;30:338-343.
14. Cheng A, Batool S, Mccreary CR, Lauzon ML, Frayne R, Smith EE. Susceptibility-weighted imaging is more reliable than T2* weighted gradient-recalled echo MRI for detecting microbleeds. Stroke. 2013;2782-2786.
15. Galimanis A, Jung S, Mono ML, Fischer U, Findling O, Weck A, et al. Endovascular therapy of 623 patients with anterior circulation stroke. Stroke. 2012;43:1052-1057.
16. Jung S, Mono ML, Fischer U, Galimanis A, Findling O, De Marchis GM, et al. Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis. Stroke. 2011;42:1946-1951.
17. Jung S, Schindler K, Findling O, Mono ML, Fischer U, Gralla J, et al. Adverse effect of early epileptic seizures in patients receiving endovas-cular therapy for acute stroke. Stroke. 2012;43:1584-1590.
18. Jung S, Gralla J, Fischer U, Mono ML, Weck A, Lüdi R, et al. Safety of endovascular treatment beyond the 6-h time window in 205 patients. Eur J Neurol. 2013;20:865-871.
19. Gregoire SM, Chaudhary UJ, Brown MM, Yousry TA, Kallis C, Jäger HR, et al. The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds. Neurology. 2009;73:1759-1766.
20. Furlan A, Higashida R, Wechsler L, Gent M, Rowley H, Kase C, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA. 1999;282:2003-2011.
21. Shoamanesh A, Kwok CS, Benavente O. Cerebral microbleeds: histopathological correlation of neuroimaging. Cerebrovasc Dis. 2011;32:528-534.
22. Lovelock CE, Cordonnier C, Naka H, Al-Shahi Salman R, Sudlow CL, Sorimachi T, et al; Edinburgh Stroke Study Group. Antithrombotic drug use, cerebral microbleeds, and intracerebral hemorrhage: a systematic review of published and unpublished studies. Stroke. 2010;41:1222-1228.
23. Soo YO, Yang SR, Lam WW, Wong A, Fan YH, Leung HH, et al. Risk vs beneft of anti-thrombotic therapy in ischaemic stroke patients with cerebral microbleeds. J Neurol. 2008;255:1679-1686.
24. Jeerakathil T, Wolf PA, Beiser A, Hald JK, Au R, Kase CS, et al. Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke. 2004;35:1831-1835.
25. Kimura K, Aoki J, Shibazaki K, Saji N, Uemura J, Sakamoto Y. New appearance of extraischemic microbleeds on T2*-weighted magnetic resonance imaging 24 hours after tissue-type plasminogen activator administration. Stroke. 2013;44:2776-2781.