Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice

Biochemical and Biophysical Research Communications

Volumn 448, Issue 4, 2014, Pages 414-417

  Zhao, Ran Ran ^a,b   Xu, Xiao Chen ^b   Xu, Fei ^b   Zhang, Wei Li ^a   Zhang, Wen Lin ^a   Liu, Liang Min ^a   Wang, Wei Ping ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b First Hospital of Handan   (China)

Author keywords

Cognition; Epilepsy; Metformin; Morris water maze; Oxidative stress

Indexed keywords

GLUTATHIONE; MALONALDEHYDE; METFORMIN; PENTETRAZOLE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ESCAPE BEHAVIOR; KINDLING; LATENT PERIOD; LEARNING DISORDER; LIPID PEROXIDATION; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SEIZURE; TONIC CLONIC SEIZURE;

ANIMALIA; MUS;

COGNITION; EPILEPSY; METFORMIN; MORRIS WATER MAZE; OXIDATIVE STRESS;

ANIMALS; ANTIOXIDANTS; BRAIN; CONVULSANTS; GLUTATHIONE; KINDLING, NEUROLOGIC; LEARNING DISORDERS; MALE; MALONDIALDEHYDE; MAZE LEARNING; MEMORY DISORDERS; METFORMIN; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PENTYLENETETRAZOLE; SEIZURES;

EID: 84901849879     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.130     Document Type: Article

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