메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages 1229-1244

3D mouse embryonic stem cell culture for generating inner ear organoids

Author keywords

[No Author keywords available]

Indexed keywords

SCLEROPROTEIN;

EID: 84901849749     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2014.100     Document Type: Article
Times cited : (110)

References (72)
  • 1
    • 84872534651 scopus 로고    scopus 로고
    • Cytosystems dynamics in self-organization of tissue architecture
    • Sasai, Y. Cytosystems dynamics in self-organization of tissue architecture. Nature 493, 318-326 (2013).
    • (2013) Nature , vol.493 , pp. 318-326
    • Sasai, Y.1
  • 2
    • 84867865709 scopus 로고    scopus 로고
    • In vitro organogenesis in three dimensions: Self-organising stem cells
    • Sasai, Y., Eiraku, M. & Suga, H. In vitro organogenesis in three dimensions: self-organising stem cells. Development 139, 4111-4121 (2012).
    • (2012) Development , vol.139 , pp. 4111-4121
    • Sasai, Y.1    Eiraku, M.2    Suga, H.3
  • 3
    • 84881474378 scopus 로고    scopus 로고
    • Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
    • Koehler, K.R., Mikosz, A.M., Molosh, A.I., Patel, D. & Hashino, E. Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature 500, 217-221 (2013).
    • (2013) Nature , vol.500 , pp. 217-221
    • Koehler, K.R.1    Mikosz, A.M.2    Molosh, A.I.3    Patel, D.4    Hashino, E.5
  • 4
    • 84883433950 scopus 로고    scopus 로고
    • Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina
    • Gonzalez-Cordero, A. et al. Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina. Nat. Biotechnol. 31, 741-747 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 741-747
    • Gonzalez-Cordero, A.1
  • 5
    • 79953749322 scopus 로고    scopus 로고
    • Self-organizing optic-cup morphogenesis in three-dimensional culture
    • Eiraku, M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51-56 (2011).
    • (2011) Nature , vol.472 , pp. 51-56
    • Eiraku, M.1
  • 6
    • 54949102049 scopus 로고    scopus 로고
    • Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals
    • Eiraku, M. et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 3, 519-532 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 519-532
    • Eiraku, M.1
  • 7
    • 84860233475 scopus 로고    scopus 로고
    • Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues
    • Eiraku, M. & Sasai, Y. Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues. Nat. Protoc. 7, 69-79 (2012).
    • (2012) Nat. Protoc. , vol.7 , pp. 69-79
    • Eiraku, M.1    Sasai, Y.2
  • 8
    • 84862526635 scopus 로고    scopus 로고
    • Self-formation of optic cups and storable stratified neural retina from human ESCs
    • Nakano, T. et al. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 10, 771-785 (2012).
    • (2012) Cell Stem Cell , vol.10 , pp. 771-785
    • Nakano, T.1
  • 9
    • 82555187011 scopus 로고    scopus 로고
    • Self-formation of functional adenohypophysis in three-dimensional culture
    • Suga, H. et al. Self-formation of functional adenohypophysis in three-dimensional culture. Nature 480, 57-62 (2011).
    • (2011) Nature , vol.480 , pp. 57-62
    • Suga, H.1
  • 10
    • 84871777952 scopus 로고    scopus 로고
    • Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture
    • Nasu, M. et al. Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture. PLoS ONE 7, e53024 (2012).
    • (2012) PLoS ONE , vol.7
    • Nasu, M.1
  • 11
    • 84884414984 scopus 로고    scopus 로고
    • Cerebral organoids model human brain development and microcephaly
    • Lancaster, M. et al. Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379 (2013).
    • (2013) Nature , vol.501 , pp. 373-379
    • Lancaster, M.1
  • 12
    • 79551686425 scopus 로고    scopus 로고
    • Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
    • Spence, J.R. et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 470, 105-109 (2010).
    • (2010) Nature , vol.470 , pp. 105-109
    • Spence, J.R.1
  • 13
    • 80955137949 scopus 로고    scopus 로고
    • Generating human intestinal tissue from pluripotent stem cells in vitro
    • McCracken, K.W., Howell, J.C., Wells, J.M. & Spence, J.R. Generating human intestinal tissue from pluripotent stem cells in vitro. Nat. Protoc. 6, 1920-1928 (2011).
    • (2011) Nat. Protoc. , vol.6 , pp. 1920-1928
    • McCracken, K.W.1    Howell, J.C.2    Wells, J.M.3    Spence, J.R.4
  • 14
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009).
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1
  • 15
    • 84873712443 scopus 로고    scopus 로고
    • In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
    • Huch, M. et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 494, 247-250 (2013).
    • (2013) Nature , vol.494 , pp. 247-250
    • Huch, M.1
  • 16
    • 84887150842 scopus 로고    scopus 로고
    • Location of transient ectodermal progenitor potential in mouse development
    • Li, L. et al. Location of transient ectodermal progenitor potential in mouse development. Development 140, 4533-4543 (2013).
    • (2013) Development , vol.140 , pp. 4533-4543
    • Li, L.1
  • 17
    • 83755186011 scopus 로고    scopus 로고
    • Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo
    • Cajal, M. et al. Clonal and molecular analysis of the prospective anterior neural boundary in the mouse embryo. Development 139, 423-436 (2012).
    • (2012) Development , vol.139 , pp. 423-436
    • Cajal, M.1
  • 18
    • 0019604166 scopus 로고
    • An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo
    • Beddington, S.P. An autoradiographic analysis of the potency of embryonic ectoderm in the 8th day postimplantation mouse embryo. J. Embryol. Exp. Morphol. 64, 87-104 (1981).
    • (1981) J. Embryol. Exp. Morphol. , vol.64 , pp. 87-104
    • Beddington, S.P.1
  • 19
    • 0020002205 scopus 로고
    • An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse
    • Beddington, R.S. An autoradiographic analysis of tissue potency in different regions of the embryonic ectoderm during gastrulation in the mouse. J. Embryol Exp. Morphol. 69, 265-285 (1982).
    • (1982) J. Embryol Exp. Morphol. , vol.69 , pp. 265-285
    • Beddington, R.S.1
  • 20
    • 0029059425 scopus 로고
    • Induction of epidermis and inhibition of neural fate by Bmp-4
    • Wilson, P.A. & Hemmati-Brivanlou, A. Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333 (1995).
    • (1995) Nature , vol.376 , pp. 331-333
    • Wilson, P.A.1    Hemmati-Brivanlou, A.2
  • 21
    • 0030886059 scopus 로고    scopus 로고
    • Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1
    • Wilson, P.A., Lagna, G., Suzuki, A. & Hemmati-Brivanlou, A. Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development 124, 3177-3184 (1997).
    • (1997) Development , vol.124 , pp. 3177-3184
    • Wilson, P.A.1    Lagna, G.2    Suzuki, A.3    Hemmati-Brivanlou, A.4
  • 22
    • 78049442567 scopus 로고    scopus 로고
    • Identification of early requirements for preplacodal ectoderm and sensory organ development
    • Kwon, H.-J., Bhat, N., Sweet, E.M., Cornell, R.A. & Riley, B.B. Identification of early requirements for preplacodal ectoderm and sensory organ development. PLoS Genet. 6, e1001133 (2010).
    • (2010) PLoS Genet. , vol.6
    • Kwon, H.-J.1    Bhat, N.2    Sweet, E.M.3    Cornell, R.A.4    Riley, B.B.5
  • 23
    • 0033405806 scopus 로고    scopus 로고
    • Bmp activity establishes a gradient of positional information throughout the entire neural plate
    • Barth, K.A. et al. Bmp activity establishes a gradient of positional information throughout the entire neural plate. Development 126, 4977-4987 (1999).
    • (1999) Development , vol.126 , pp. 4977-4987
    • Barth, K.A.1
  • 24
    • 0030919925 scopus 로고    scopus 로고
    • A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish
    • Neave, B., Holder, N. & Patient, R. A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish. Mech. Dev. 62, 183-195 (1997).
    • (1997) Mech. Dev. , vol.62 , pp. 183-195
    • Neave, B.1    Holder, N.2    Patient, R.3
  • 25
    • 77952341830 scopus 로고    scopus 로고
    • Response to BMP4 signalling during ES cell differentiation defines intermediates of the ectoderm lineage
    • Harvey, N.T. et al. Response to BMP4 signalling during ES cell differentiation defines intermediates of the ectoderm lineage. J. Cell Sci. 123, 1796-1804 (2010).
    • (2010) J. Cell Sci. , vol.123 , pp. 1796-1804
    • Harvey, N.T.1
  • 26
    • 84857286576 scopus 로고    scopus 로고
    • Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm
    • Pieper, M., Ahrens, K., Rink, E., Peter, A. & Schlosser, G. Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm. Development 139, 1175-1187 (2012).
    • (2012) Development , vol.139 , pp. 1175-1187
    • Pieper, M.1    Ahrens, K.2    Rink, E.3    Peter, A.4    Schlosser, G.5
  • 27
    • 84885659822 scopus 로고    scopus 로고
    • A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border
    • Reichert, S., Randall, R.A. & Hill, C.S. A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border. Development 140, 4435-4444 (2013).
    • (2013) Development , vol.140 , pp. 4435-4444
    • Reichert, S.1    Randall, R.A.2    Hill, C.S.3
  • 28
    • 84865649528 scopus 로고    scopus 로고
    • The peripheral sensory nervous system in the vertebrate head: A gene regulatory perspective
    • Grocott, T., Tambalo, M. & Streit, A. The peripheral sensory nervous system in the vertebrate head: a gene regulatory perspective. Dev. Biol. 370, 3-23 (2012).
    • (2012) Dev. Biol. , vol.370 , pp. 3-23
    • Grocott, T.1    Tambalo, M.2    Streit, A.3
  • 29
    • 27144532442 scopus 로고    scopus 로고
    • Tissues and signals involved in the induction of placodal Six1 expression in Xenopus laevis
    • Ahrens, K. & Schlosser, G. Tissues and signals involved in the induction of placodal Six1 expression in Xenopus laevis. Dev. Biol. 288, 40-59 (2005).
    • (2005) Dev. Biol. , vol.288 , pp. 40-59
    • Ahrens, K.1    Schlosser, G.2
  • 30
    • 12344249105 scopus 로고    scopus 로고
    • Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor
    • Brugmann, S.A., Pandur, P.D., Kenyon, K.L., Pignoni, F. & Moody, S.A. Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. Development 131, 5871-5881 (2004).
    • (2004) Development , vol.131 , pp. 5871-5881
    • Brugmann, S.A.1    Pandur, P.D.2    Kenyon, K.L.3    Pignoni, F.4    Moody, S.A.5
  • 31
    • 27144449720 scopus 로고    scopus 로고
    • A balance of FGF, BMP and WNT signalling positions the future placode territory in the head
    • Litsiou, A., Hanson, S. & Streit, A. A balance of FGF, BMP and WNT signalling positions the future placode territory in the head. Development 132, 4051-4062 (2005).
    • (2005) Development , vol.132 , pp. 4051-4062
    • Litsiou, A.1    Hanson, S.2    Streit, A.3
  • 32
    • 33744992190 scopus 로고    scopus 로고
    • Induction and specification of cranial placodes
    • Schlosser, G. Induction and specification of cranial placodes. Dev. Biol. 294, 303-351 (2006).
    • (2006) Dev. Biol. , vol.294 , pp. 303-351
    • Schlosser, G.1
  • 33
    • 81855192739 scopus 로고    scopus 로고
    • Specification and regionalisation of the neural plate border
    • Patthey, C. & Gunhaga, L. Specification and regionalisation of the neural plate border. Eur. J. Neurosci. 34, 1516-1528 (2011).
    • (2011) Eur. J. Neurosci. , vol.34 , pp. 1516-1528
    • Patthey, C.1    Gunhaga, L.2
  • 34
    • 60849138439 scopus 로고    scopus 로고
    • Competence specification and commitment to an olfactory placode fate
    • Bhattacharyya, S. & Bronner-Fraser, M. Competence, specification and commitment to an olfactory placode fate. Development 135, 4165-4177 (2008).
    • (2008) Development , vol.135 , pp. 4165-4177
    • Bhattacharyya, S.1    Bronner-Fraser, M.2
  • 35
    • 0032934999 scopus 로고    scopus 로고
    • Competence specification and induction of Pax-3 in the trigeminal placode
    • Baker, C.V., Stark, M.R., Marcelle, C. & Bronner-Fraser, M. Competence, specification and induction of Pax-3 in the trigeminal placode. Development 126, 147-156 (1999).
    • (1999) Development , vol.126 , pp. 147-156
    • Baker, C.V.1    Stark, M.R.2    Marcelle, C.3    Bronner-Fraser, M.4
  • 36
    • 77952225103 scopus 로고    scopus 로고
    • From shared lineage to distinct functions: The development of the inner ear and epibranchial placodes
    • Ladher, R.K., O'Neill, P. & Begbie, J. From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes. Development 137, 1777-1785 (2010).
    • (2010) Development , vol.137 , pp. 1777-1785
    • Ladher, R.K.1    O'Neill, P.2    Begbie, J.3
  • 37
    • 0042831024 scopus 로고    scopus 로고
    • Fgf3 and Fgf10 are required for mouse otic placode induction
    • Wright, T.J. & Mansour, S.L. Fgf3 and Fgf10 are required for mouse otic placode induction. Development 130, 3379-3390 (2003).
    • (2003) Development , vol.130 , pp. 3379-3390
    • Wright, T.J.1    Mansour, S.L.2
  • 38
    • 77951207217 scopus 로고    scopus 로고
    • FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a
    • Urness, L.D., Paxton, C.N., Wang, X., Schoenwolf, G.C. & Mansour, S.L. FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev. Biol. 340, 595-604 (2010).
    • (2010) Dev. Biol. , vol.340 , pp. 595-604
    • Urness, L.D.1    Paxton, C.N.2    Wang, X.3    Schoenwolf, G.C.4    Mansour, S.L.5
  • 39
    • 33645542086 scopus 로고    scopus 로고
    • Wnt signals mediate a fate decision between otic placode and epidermis
    • Ohyama, T., Mohamed, O.A., Taketo, M.M., Dufort, D. & Groves, A.K. Wnt signals mediate a fate decision between otic placode and epidermis. Development 133, 865-875 (2006).
    • (2006) Development , vol.133 , pp. 865-875
    • Ohyama, T.1    Mohamed, O.A.2    Taketo, M.M.3    Dufort, D.4    Groves, A.K.5
  • 40
    • 22344451138 scopus 로고    scopus 로고
    • Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh
    • Riccomagno, M.M., Takada, S. & Epstein, D.J. Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. Genes Dev. 19, 1612-1623 (2005).
    • (2005) Genes Dev. , vol.19 , pp. 1612-1623
    • Riccomagno, M.M.1    Takada, S.2    Epstein, D.J.3
  • 41
    • 58149241397 scopus 로고    scopus 로고
    • Progressive restriction of otic fate: The role of FGF and Wnt in resolving inner ear potential
    • Freter, S., Muta, Y., Mak, S.-S., Rinkwitz, S. & Ladher, R.K. Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential. Development 135, 3415-3424 (2008).
    • (2008) Development , vol.135 , pp. 3415-3424
    • Freter, S.1    Muta, Y.2    Mak, S.-S.3    Rinkwitz, S.4    Ladher, R.K.5
  • 42
    • 0033833143 scopus 로고    scopus 로고
    • Competence specification and commitment in otic placode induction
    • Groves, A.K. & Bronner-Fraser, M. Competence, specification and commitment in otic placode induction. Development 127, 3489-3499 (2000).
    • (2000) Development , vol.127 , pp. 3489-3499
    • Groves, A.K.1    Bronner-Fraser, M.2
  • 43
    • 83755206463 scopus 로고    scopus 로고
    • Shaping sound in space: The regulation of inner ear patterning
    • Groves, A.K. & Fekete, D.M. Shaping sound in space: the regulation of inner ear patterning. Development 139, 245-257 (2011).
    • (2011) Development , vol.139 , pp. 245-257
    • Groves, A.K.1    Fekete, D.M.2
  • 44
    • 79951529175 scopus 로고    scopus 로고
    • Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: A mechanism for sensory organ specification
    • Neves, J., Parada, C., Chamizo, M. & Giraldez, F. Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification. Development 138, 735-744 (2011).
    • (2011) Development , vol.138 , pp. 735-744
    • Neves, J.1    Parada, C.2    Chamizo, M.3    Giraldez, F.4
  • 45
    • 79953070455 scopus 로고    scopus 로고
    • Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly
    • Appler, J.M. & Goodrich, L.V. Connecting the ear to the brain: molecular mechanisms of auditory circuit assembly. Prog. Neurobiol. 93, 488-508 (2011).
    • (2011) Prog. Neurobiol. , vol.93 , pp. 488-508
    • Appler, J.M.1    Goodrich, L.V.2
  • 46
    • 70450221492 scopus 로고    scopus 로고
    • Cell cycle regulation in the inner ear sensory epithelia: Role of cyclin D1 and cyclin-dependent kinase inhibitors
    • Laine, H., Sulg, M., Kirjavainen, A. & Pirvola, U. Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors. Dev. Biol. 337, 134-146 (2010).
    • (2010) Dev. Biol. , vol.337 , pp. 134-146
    • Laine, H.1    Sulg, M.2    Kirjavainen, A.3    Pirvola, U.4
  • 48
    • 0031770385 scopus 로고    scopus 로고
    • Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
    • Xiang, M., Gao, W.Q., Hasson, T. & Shin, J.J. Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development 125, 3935-3946 (1998).
    • (1998) Development , vol.125 , pp. 3935-3946
    • Xiang, M.1    Gao, W.Q.2    Hasson, T.3    Shin, J.J.4
  • 49
    • 14544296563 scopus 로고    scopus 로고
    • Directed differentiation of telencephalic precursors from embryonic stem cells
    • Watanabe, K. et al. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat. Neurosci. 8, 288-296 (2005).
    • (2005) Nat. Neurosci. , vol.8 , pp. 288-296
    • Watanabe, K.1
  • 50
    • 0036546980 scopus 로고    scopus 로고
    • Neural induction, the default model and embryonic stem cells
    • Muñoz-Sanjuán, I. & Brivanlou, A.H. Neural induction, the default model and embryonic stem cells. Nat. Rev. Neurosci. 3, 271-280 (2002).
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 271-280
    • Muñoz-Sanjuán, I.1    Brivanlou, A.H.2
  • 51
    • 16244400050 scopus 로고    scopus 로고
    • TGF-β/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James, D., Levine, A.J., Besser, D. & Hemmati-Brivanlou, A. TGF-β/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132, 1273-1282 (2005).
    • (2005) Development , vol.132 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 52
    • 33745256758 scopus 로고    scopus 로고
    • Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo
    • Camus, A., Perea-Gomez, A., Moreau, A. & Collignon, J. Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo. Dev. Biol. 295, 743-755 (2006).
    • (2006) Dev. Biol. , vol.295 , pp. 743-755
    • Camus, A.1    Perea-Gomez, A.2    Moreau, A.3    Collignon, J.4
  • 53
    • 62149125434 scopus 로고    scopus 로고
    • Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
    • Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27, 275-280 (2009).
    • (2009) Nat. Biotechnol , vol.27 , pp. 275-280
    • Chambers, S.M.1
  • 54
    • 77957274777 scopus 로고    scopus 로고
    • Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells
    • Muguruma, K. et al. Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells. Nat. Neurosci. 13, 1171-1180 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 1171-1180
    • Muguruma, K.1
  • 55
  • 57
    • 59949087742 scopus 로고    scopus 로고
    • Expression of the Pax2 transcription factor is associated with vestibular phenotype in the avian inner ear
    • Warchol, M.E. & Richardson, G.P. Expression of the Pax2 transcription factor is associated with vestibular phenotype in the avian inner ear. Dev. Neurobiol. 69, 191-202 (2009).
    • (2009) Dev. Neurobiol. , vol.69 , pp. 191-202
    • Warchol, M.E.1    Richardson, G.P.2
  • 58
    • 79960045681 scopus 로고    scopus 로고
    • Molecular microdomains in a sensory terminal, the vestibular calyx ending
    • Lysakowski, A. et al. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J. Neurosci. 31, 10101-10114 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 10101-10114
    • Lysakowski, A.1
  • 59
    • 39149139311 scopus 로고    scopus 로고
    • Architecture of the mouse utricle: Macular organization and hair bundle heights
    • Li, A., Xue, J. & Peterson, E.H. Architecture of the mouse utricle: macular organization and hair bundle heights. J. Neurophysiol. 99, 718-733 (2008).
    • (2008) J. Neurophysiol , vol.99 , pp. 718-733
    • Li, A.1    Xue, J.2    Peterson, E.H.3
  • 60
    • 0344633590 scopus 로고    scopus 로고
    • Generation of hair cells by stepwise differentiation of embryonic stem cells
    • Li, H., Roblin, G., Liu, H. & Heller, S. Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. USA 100, 13495-13500 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13495-13500
    • Li, H.1    Roblin, G.2    Liu, H.3    Heller, S.4
  • 61
    • 77952493569 scopus 로고    scopus 로고
    • Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells
    • Oshima, K. et al. Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell 141, 704-716 (2010).
    • (2010) Cell , vol.141 , pp. 704-716
    • Oshima, K.1
  • 62
    • 84861562959 scopus 로고    scopus 로고
    • In vitro differentiation of mouse embryonic stem cells into inner ear hair cell-like cells using stromal cell conditioned medium
    • Ouji, Y., Ishizaka, S., Nakamura-Uchiyama, F. & Yoshikawa, M. In vitro differentiation of mouse embryonic stem cells into inner ear hair cell-like cells using stromal cell conditioned medium. Cell Death Dis. 3, e314 (2012).
    • (2012) Cell Death Dis. , vol.3
    • Ouji, Y.1    Ishizaka, S.2    Nakamura-Uchiyama, F.3    Yoshikawa, M.4
  • 63
    • 84867337075 scopus 로고    scopus 로고
    • Restoration of auditory evoked responses by human ES-cell-derived otic progenitors
    • Chen, W. et al. Restoration of auditory evoked responses by human ES-cell-derived otic progenitors. Nature 490, 278-282 (2012).
    • (2012) Nature , vol.490 , pp. 278-282
    • Chen, W.1
  • 65
    • 66749086828 scopus 로고    scopus 로고
    • Quo vadis, hair cell regeneration?
    • Brigande, J.V. & Heller, S. Quo vadis, hair cell regeneration? Nat. Neurosci. 12, 679-685 (2009).
    • (2009) Nat. Neurosci. , vol.12 , pp. 679-685
    • Brigande, J.V.1    Heller, S.2
  • 66
    • 84873733109 scopus 로고    scopus 로고
    • A TALEN genome-editing system for generating human stem cell-based disease models
    • Ding, Q. et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell 12, 238-251 (2013).
    • (2013) Cell Stem Cell , vol.12 , pp. 238-251
    • Ding, Q.1
  • 67
    • 84875963894 scopus 로고    scopus 로고
    • Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs
    • Ding, Q. et al. Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. Cell Stem Cell 12, 393-394 (2013).
    • (2013) Cell Stem Cell , vol.12 , pp. 393-394
    • Ding, Q.1
  • 68
    • 77952581962 scopus 로고    scopus 로고
    • Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse
    • Trowe, M.-O. et al. Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse. Dev. Biol. 342, 51-62 (2010).
    • (2010) Dev. Biol. , vol.342 , pp. 51-62
    • Trowe, M.-O.1
  • 69
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying, Q.-L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519-523 (2008).
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.-L.1
  • 70
    • 18844390247 scopus 로고    scopus 로고
    • Three-dimensional culture of newborn rat utricle using an extracellular matrix promotes formation of a cyst
    • Gaboyard, S. et al. Three-dimensional culture of newborn rat utricle using an extracellular matrix promotes formation of a cyst. Neuroscience 133, 253-265 (2005).
    • (2005) Neuroscience , vol.133 , pp. 253-265
    • Gaboyard, S.1
  • 72
    • 84863181231 scopus 로고    scopus 로고
    • Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos
    • Yokomizo, T. et al. Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos. Nat. Protoc. 7, 421-431 (2012).
    • (2012) Nat. Protoc. , vol.7 , pp. 421-431
    • Yokomizo, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.