메뉴 건너뛰기




Volumn 111, Issue 22, 2014, Pages

DA-Raf-dependent inhibition of the Ras-ERK signaling pathway in type 2 alveolar epithelial cells controls alveolar formation

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; RAF PROTEIN; RAS PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 4;

EID: 84901825573     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321574111     Document Type: Article
Times cited : (15)

References (57)
  • 1
    • 74049139927 scopus 로고    scopus 로고
    • Preparing for the first breath: Genetic and cellular mechanisms in lung development
    • Morrisey EE, Hogan BL (2010) Preparing for the first breath: Genetic and cellular mechanisms in lung development. Dev Cell 18(1):8-23.
    • (2010) Dev Cell , vol.18 , Issue.1 , pp. 8-23
    • Morrisey, E.E.1    Hogan, B.L.2
  • 2
    • 33744524149 scopus 로고    scopus 로고
    • Regulation of early lung morphogenesis: Questions, facts and controversies
    • DOI 10.1242/dev.02310
    • Cardoso WV, Lü J (2006) Regulation of early lung morphogenesis: Questions, facts and controversies. Development 133(9):1611-1624. (Pubitemid 43810969)
    • (2006) Development , vol.133 , Issue.9 , pp. 1611-1624
    • Cardoso, W.V.1    Lu, J.2
  • 3
    • 0030730837 scopus 로고    scopus 로고
    • Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development
    • Lindahl P, et al. (1997) Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development 124(20):3943-3953. (Pubitemid 27483322)
    • (1997) Development , vol.124 , Issue.20 , pp. 3943-3953
    • Lindahl, P.1    Karlsson, L.2    Hellstrom, M.3    Gebre-Medhin, S.4    Willetts, K.5    Heath, J.K.6    Betsholtz, C.7
  • 5
    • 77649241067 scopus 로고    scopus 로고
    • PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts
    • Kimani PW, Holmes AJ, Grossmann RE, McGowan SE (2009) PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts. Respir Res 10:119.
    • (2009) Respir Res , vol.10 , pp. 119
    • Kimani, P.W.1    Holmes, A.J.2    Grossmann, R.E.3    McGowan, S.E.4
  • 6
    • 58149394472 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-alpha-expressing cells localize to the alveolar entry ring and have characteristics of myofibroblasts during pulmonary alveolar septal formation
    • McGowan SE, Grossmann RE, Kimani PW, Holmes AJ (2008) Platelet-derived growth factor receptor-alpha-expressing cells localize to the alveolar entry ring and have characteristics of myofibroblasts during pulmonary alveolar septal formation. Anat Rec (Hoboken) 291(12):1649-1661.
    • (2008) Anat Rec (Hoboken) , vol.291 , Issue.12 , pp. 1649-1661
    • McGowan, S.E.1    Grossmann, R.E.2    Kimani, P.W.3    Holmes, A.J.4
  • 7
    • 33745069841 scopus 로고    scopus 로고
    • Structural aspects of postnatal lung development-Alveolar formation and growth
    • Burri PH (2006) Structural aspects of postnatal lung development-Alveolar formation and growth. Biol Neonate 89(4):313-322.
    • (2006) Biol Neonate , vol.89 , Issue.4 , pp. 313-322
    • Burri, P.H.1
  • 9
    • 17844398531 scopus 로고    scopus 로고
    • Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia
    • Bourbon J, Boucherat O, Chailley-Heu B, Delacourt C (2005) Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia. Pediatr Res 57(5 Pt 2):38R-46R. (Pubitemid 40593244)
    • (2005) Pediatric Research , vol.57 , Issue.5 II
    • Bourbon, J.1    Boucherat, O.2    Chailley-Heu, B.3    Delacourt, C.4
  • 10
    • 37549053643 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions
    • Ambalavanan N, et al. (2008) Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions. Pediatr Res 63(1):26-32.
    • (2008) Pediatr Res , vol.63 , Issue.1 , pp. 26-32
    • Ambalavanan, N.1
  • 12
    • 0037084399 scopus 로고    scopus 로고
    • Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2
    • Kheradmand F, Rishi K, Werb Z (2002) Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2. J Cell Sci 115(Pt 4):839-848. (Pubitemid 34196343)
    • (2002) Journal of Cell Science , vol.115 , Issue.4 , pp. 839-848
    • Kheradmand, F.1    Rishi, K.2    Werb, Z.3
  • 13
    • 80155137529 scopus 로고    scopus 로고
    • Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization
    • Ding BS, et al. (2011) Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147(3):539-553.
    • (2011) Cell , vol.147 , Issue.3 , pp. 539-553
    • Ding, B.S.1
  • 15
    • 79960487665 scopus 로고    scopus 로고
    • Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape
    • Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR (2011) Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape. Science 333(6040):342-345.
    • (2011) Science , vol.333 , Issue.6040 , pp. 342-345
    • Tang, N.1    Marshall, W.F.2    McMahon, M.3    Metzger, R.J.4    Martin, G.R.5
  • 16
    • 84887308205 scopus 로고    scopus 로고
    • Lung epithelial branching program antagonizes alveolar differentiation
    • Chang DR, et al. (2013) Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci USA 110(45):18042-18051.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.45 , pp. 18042-18051
    • Chang, D.R.1
  • 17
    • 84862294189 scopus 로고    scopus 로고
    • ERK1/2 MAP kinases: Structure, function, and regulation
    • Roskoski R, Jr. (2012) ERK1/2 MAP kinases: Structure, function, and regulation. Pharmacol Res 66(2):105-143.
    • (2012) Pharmacol Res , vol.66 , Issue.2 , pp. 105-143
    • Roskoski Jr., R.1
  • 18
    • 84855795110 scopus 로고    scopus 로고
    • MEK1/2 dual-specificity protein kinases: Structure and regulation
    • Roskoski R, Jr. (2012) MEK1/2 dual-specificity protein kinases: Structure and regulation. Biochem Biophys Res Commun 417(1):5-10.
    • (2012) Biochem Biophys Res Commun , vol.417 , Issue.1 , pp. 5-10
    • Roskoski Jr., R.1
  • 19
    • 77956124562 scopus 로고    scopus 로고
    • RAF protein-serine/threonine kinases: Structure and regulation
    • Roskoski R, Jr. (2010) RAF protein-serine/threonine kinases: Structure and regulation. Biochem Biophys Res Commun 399(3):313-317.
    • (2010) Biochem Biophys Res Commun , vol.399 , Issue.3 , pp. 313-317
    • Roskoski Jr., R.1
  • 20
    • 34249880794 scopus 로고    scopus 로고
    • DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation
    • DOI 10.1083/jcb.200703195
    • Yokoyama T, et al. (2007) DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation. J Cell Biol 177(5):781-793. (Pubitemid 46873085)
    • (2007) Journal of Cell Biology , vol.177 , Issue.5 , pp. 781-793
    • Yokoyama, T.1    Takano, K.2    Yoshida, A.3    Katada, F.4    Sun, P.5    Takenawa, T.6    Andoh, T.7    Endo, T.8
  • 22
    • 60849098434 scopus 로고    scopus 로고
    • Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts
    • Kim Y, et al. (2009) Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. J Cell Biol 184(2):309-322.
    • (2009) J Cell Biol , vol.184 , Issue.2 , pp. 309-322
    • Kim, Y.1
  • 23
    • 70349441112 scopus 로고    scopus 로고
    • Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
    • Tanjore H, et al. (2009) Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med 180(7):657-665.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.7 , pp. 657-665
    • Tanjore, H.1
  • 24
    • 84855511323 scopus 로고    scopus 로고
    • Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
    • Rock JR, et al. (2011) Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci USA 108(52):E1475-E1483.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.52
    • Rock, J.R.1
  • 25
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21(1):70-71.
    • (1999) Nat Genet , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 28
    • 0030904130 scopus 로고    scopus 로고
    • 'Green mice' as a source of ubiquitous green cells
    • DOI 10.1016/S0014-5793(97)00313-X, PII S001457939700313X
    • Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y (1997) 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407(3):313-319. (Pubitemid 27199450)
    • (1997) FEBS Letters , vol.407 , Issue.3 , pp. 313-319
    • Okabe, M.1    Ikawa, M.2    Kominami, K.3    Nakanishi, T.4    Nishimune, Y.5
  • 30
    • 81255188391 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases
    • Murphy G (2011) Tissue inhibitors of metalloproteinases. Genome Biol 12(11):233.
    • (2011) Genome Biol , vol.12 , Issue.11 , pp. 233
    • Murphy, G.1
  • 31
    • 77957281923 scopus 로고    scopus 로고
    • Coordinate action of membrane-type matrix metal-loproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion
    • Sato H, Takino T (2010) Coordinate action of membrane-type matrix metal-loproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion. Cancer Sci 101(4):843-847.
    • (2010) Cancer Sci , vol.101 , Issue.4 , pp. 843-847
    • Sato, H.1    Takino, T.2
  • 34
    • 23844494402 scopus 로고    scopus 로고
    • The duration, magnitude and compartmentalization of ERK MAP kinase activity: Mechanisms for providing signaling specificity
    • DOI 10.1242/jcs.02505
    • Ebisuya M, Kondoh K, Nishida E (2005) The duration, magnitude and compartmentalization of ERK MAP kinase activity: Mechanisms for providing signaling specificity. J Cell Sci 118(Pt 14):2997-3002. (Pubitemid 41149904)
    • (2005) Journal of Cell Science , vol.118 , Issue.14 , pp. 2997-3002
    • Ebisuya, M.1    Kondoh, K.2    Nishida, E.3
  • 35
    • 0030133927 scopus 로고    scopus 로고
    • Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene
    • Pritchard CA, Bolin L, Slattery R, Murray R, McMahonM(1996) Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene. Curr Biol 6(5):614-617. (Pubitemid 126656319)
    • (1996) Current Biology , vol.6 , Issue.5 , pp. 614-617
    • Pritchard, C.A.1    Bolin, L.2    Slattery, R.3    Murray, R.4    McMahon, M.5
  • 40
    • 84862913236 scopus 로고    scopus 로고
    • Enhanced expression of tissue inhibitor of metalloproteinases-4 gene in human osteoarthritic synovial membranes and its differential regulation by cytokines in chondrocytes
    • Huang W, Mabrouk ME, Sylvester J, Dehnade F, Zafarullah M (2011) Enhanced expression of tissue inhibitor of metalloproteinases-4 gene in human osteoarthritic synovial membranes and its differential regulation by cytokines in chondrocytes. Open Rheumatol J 5:81-87.
    • (2011) Open Rheumatol J , vol.5 , pp. 81-87
    • Huang, W.1    Mabrouk, M.E.2    Sylvester, J.3    Dehnade, F.4    Zafarullah, M.5
  • 42
    • 0033146396 scopus 로고    scopus 로고
    • Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma
    • Kim TS, Kim YB (1999) Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma. J Korean Med Sci 14(3):263-270.
    • (1999) J Korean Med Sci , vol.14 , Issue.3 , pp. 263-270
    • Kim, T.S.1    Kim, Y.B.2
  • 45
    • 0036741135 scopus 로고    scopus 로고
    • Molecular determinants of metalloproteinase substrate specificity: Matrix metalloproteinase substrate binding domains, modules, and exosites
    • Overall CM (2002) Molecular determinants of metalloproteinase substrate specificity: Matrix metalloproteinase substrate binding domains, modules, and exosites. Mol Biotechnol 22(1):51-86.
    • (2002) Mol Biotechnol , vol.22 , Issue.1 , pp. 51-86
    • Overall, C.M.1
  • 46
    • 77953045672 scopus 로고    scopus 로고
    • Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis
    • Srisuma S, et al. (2010) Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis. Am J Respir Crit Care Med 181(8):838-850.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.8 , pp. 838-850
    • Srisuma, S.1
  • 47
    • 0031700905 scopus 로고    scopus 로고
    • FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
    • Weinstein M, Xu X, Ohyama K, Deng CX (1998) FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125(18):3615-3623. (Pubitemid 28469962)
    • (1998) Development , vol.125 , Issue.18 , pp. 3615-3623
    • Weinstein, M.1    Xu, X.2    Ohyama, K.3    Deng, C.-X.4
  • 48
    • 3242773564 scopus 로고    scopus 로고
    • Mechanisms and limits of induced postnatal lung growth
    • Ad Hoc Statement Committee of the American Thoracic Society
    • Ad Hoc Statement Committee of the American Thoracic Society (2004) Mechanisms and limits of induced postnatal lung growth. Am J Respir Crit Care Med 170(3):319-343.
    • (2004) Am J Respir Crit Care Med , vol.170 , Issue.3 , pp. 319-343
  • 49
    • 84863992207 scopus 로고    scopus 로고
    • Evidence for adult lung growth in humans
    • Butler JP, et al. (2012) Evidence for adult lung growth in humans. N Engl J Med 367(3):244-247.
    • (2012) N Engl J Med , vol.367 , Issue.3 , pp. 244-247
    • Butler, J.P.1
  • 50
    • 84867002819 scopus 로고    scopus 로고
    • Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization
    • Chen L, Acciani T, Le Cras T, Lutzko C, Perl AK (2012) Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization. Am J Respir Cell Mol Biol 47(4):517-527.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , Issue.4 , pp. 517-527
    • Chen, L.1    Acciani, T.2    Le Cras, T.3    Lutzko, C.4    Perl, A.K.5
  • 51
    • 75749129053 scopus 로고    scopus 로고
    • Assessment of air space size characteristics by intercept (chord) measurement: An accurate and efficient stereological approach
    • Knudsen L, Weibel ER, Gundersen HJ, Weinstein FV, Ochs M (2010) Assessment of air space size characteristics by intercept (chord) measurement: An accurate and efficient stereological approach. J Appl Physiol 108(2):412-421.
    • (2010) J Appl Physiol , vol.108 , Issue.2 , pp. 412-421
    • Knudsen, L.1    Weibel, E.R.2    Gundersen, H.J.3    Weinstein, F.V.4    Ochs, M.5
  • 52
    • 76149084817 scopus 로고    scopus 로고
    • An official research policy statement of the American Thoracic Society/European Respiratory Society: Standards for quantitative assessment of lung structure
    • ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure
    • Hsia CC, Hyde DM, Ochs M, Weibel ER; ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure (2010) An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med 181(4):394-418.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.4 , pp. 394-418
    • Hsia, C.C.1    Hyde, D.M.2    Ochs, M.3    Weibel, E.R.4
  • 53
    • 42949099909 scopus 로고    scopus 로고
    • Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice
    • Fehrenbach H, et al. (2008) Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice. Eur Respir J 31(3):515-522.
    • (2008) Eur Respir J , vol.31 , Issue.3 , pp. 515-522
    • Fehrenbach, H.1
  • 55
    • 0023258851 scopus 로고
    • Isolation, biochemical characterization, and culture of lung Type II cells of the rat
    • Richards RJ, Davies N, Atkins J, Oreffo VI (1987) Isolation, biochemical characterization, and culture of lung type II cells of the rat. Lung 165(3):143-158. (Pubitemid 17083611)
    • (1987) Lung , vol.165 , Issue.3 , pp. 143-158
    • Richards, R.J.1    Davies, N.2    Atkins, J.3    Oreffo, V.I.C.4
  • 56
    • 72149091706 scopus 로고    scopus 로고
    • M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation
    • Watanabe-Takano H, Takano K, Keduka E, Endo T (2010) M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation. Exp Cell Res 316(3):477-490.
    • (2010) Exp Cell Res , vol.316 , Issue.3 , pp. 477-490
    • Watanabe-Takano, H.1    Takano, K.2    Keduka, E.3    Endo, T.4
  • 57
    • 67650498443 scopus 로고    scopus 로고
    • Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations
    • Ciuffreda L, et al. (2009) Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations. Neoplasia 11(8):720-731.
    • (2009) Neoplasia , vol.11 , Issue.8 , pp. 720-731
    • Ciuffreda, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.