Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions

Pediatric Research

Volumn 63, Issue 1, 2008, Pages 26-32

  Ambalavanan, Namasivayam ^a,b,e   Nicola, Teodora ^a   Li, Peng ^c   Bulger, Arlene ^a   Murphy Ullrich, Joanne ^d   Oparil, Suzanne ^c   Chen, Yiu Fai ^c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; DOXYCYCLINE; ELASTIN; GELATINASE A; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY WALL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; HYPOXIA; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL; LUNG DEVELOPMENT; LUNG MALFORMATION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PULMONARY ARTERY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOLOGY; TISSUE REPAIR; ZYMOGRAPHY;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; COLLAGEN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DOXYCYCLINE; ELASTIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LUNG; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEASE INHIBITORS; PULMONARY ALVEOLI; PULMONARY ARTERY; RNA, MESSENGER; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 37549053643     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31815b690d     Document Type: Article

References (38)

1. Haworth SG, Hislop AA 2003 Lung development-the effects of chronic hypoxia. Semin Neonatol 8:1-8
2. Walsh-Sukys MC 1993 Persistent pulmonary hypertension of the newborn. The black box revisited. Clin Perinatol 20:127-143
3. Goodman G, Perkin RM, Anas NG, Sperling DR, Hicks DA, Rowen M 1988 Pulmonary hypertension in infants with bronchopulmonary dysplasia. J Pediatr 112:67-71
4. Hoffmeister HM, Apitz J, Hoffmeister HE, Fischbach H 1981 The correlation between blood pressure and morphometric findings in children with congenital heart disease and pulmonary hypertension. Basic Res Cardiol 76:647-656
5. Steinhorn RH, Fineman JR 1999 The pathophysiology of pulmonary hypertension in congenital heart disease. Artif Organs 23:970-974
6. Blanco LN, Massaro D, Massaro GD 1991 Alveolar size, number, and surface area: developmentally dependent response to 13% O2. Am J Physiol 261:L370-L377
7. Massaro D, Massaro GD 2002 Invited review: pulmonary alveoli: formation, the "call for oxygen," and other regulators. Am J Physiol Lung Cell Mol Physiol 282:L345-L358
8. Thurlbeck WM 1975 Postnatal growth and development of the lung. Am Rev Respir Dis 111:803-844
9. Burri P. 1997 Structural aspects of prenatal and postnatal development and growth for the lung. In: McDonald JA (ed) Lung Growth and Development. Dekker, New York, pp 1-35
10. Stetler-Stevenson WG, Yu AE 2001 Proteases in invasion: matrix metalloproteinases. Semin Cancer Biol 11:143-152
11. Herget J, Novotna J, Bibova J, Povysilova V, Vankova M, Hampl V 2003 Metalloproteinase inhibition by Batimastat attenuates pulmonary hypertension in chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 285:L199-L208
12. Mackay AR, Hartzler JL, Pelina MD, Thorgeirsson UP 1990 Studies on the ability of 65-kDa and 92-kDa tumor cell gelatinases to degrade type IV collagen. J Biol Chem 265:21929-21934
13. Fukuda Y, Ishizaki M, Okada Y, Seiki M, Yamanaka N 2000 Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung. Am J Physiol Lung Cell Mol Physiol 279:L555-L561
14. Ryu J, Vicencio AG, Yeager ME, Kashgarian M, Haddad GG, Eickelberg O 2005 Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development. Thromb Haemost 94:175-183
15. Senior RM, Griffin GL, Fliszar CJ, Shapiro SD, Goldberg GI, Welgus HG 1991 Human 92- and 72-kilodalton type IV collagenases are elastases. J Biol Chem 266:7870-7875
16. Pardo A, Selman M 1996 Matrix metalloproteinases and lung injury. Braz J Med Biol Res 29:1109-1115
17. Frisdal E, Gest V, Vieillard-Baron A, Levame M, Lepetit H, Eddahibi S, Lafuma C, Harf A, Adnot S, Dortho MP 2001 Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension. Eur Respir J 18:838-845
18. Murphy G, Stanton H, Cowell S, Butler G, Knauper V, Atkinson S, Gavrilovic J 1999 Mechanisms for pro matrix metalloproteinase activation. APMIS 107:38-44
19. Nagase H 1998 Cell surface activation of progelatinase A (proMMP-2) and cell migration. Cell Res 8:179-186
20. Corcoran ML, Hewitt RE, Kleiner DE, Jr. Stetler-Stevenson WG 1996 MMP-2: expression, activation and inhibition. Enzyme Protein 49:7-19
21. Butler GS, Butler MJ, Atkinson SJ, Will H, Tamura T, van Westrum SS, Crabbe T, Clements J, d'Ortho MP, Murphy G 1998 The TIMP-2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J Biol Chem 273:871-880
22. Ambalavanan N, Bulger A, Murphy-Ullrich J, Oparil S, Chen YF 2005 Endothelin-A receptor blockade prevents and partially reverses neonatal hypoxic pulmonary vascular remodeling. Pediatr Res 57:631-636
23. Itoh T, Ikeda T, Gomi H, Nakao S, Suzuki T, Itohara S 1997 Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. J Biol Chem 272:22389-22392
24. Manning MW, Cassis LA, Daugherty A 2003 Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 23:483-488
25. Brey EM, Lalani Z, Johnston C, Wong M, McIntire LV, Duke PJ, Patrick CW Jr. 2003 Automated selection of DAB-labeled tissue for immunohistochemical quantification. J Histochem Cytochem 51:575-584
26. McGowan S, Jackson SK, Jenkins-Moore M, Dai HH, Chambon P, Snyder JM 2000 Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am J Respir Cell Mol Biol 23:162-167
27. Cooney TP, Thurlbeck WM 1982 The radial alveolar count method of Emery and Mithal: a reappraisal 1; postnatal lung growth. Thorax 37:572-579
28. Ambalavanan N, Li P, Bulger A, Murphy-Ullrich J, Anderson PG, Oparil S, Chen YF 2007 Endothelin-1 mediates hypoxia-induced increases in vascular collagen in the newborn mouse lung. Pediatr Res 61:559-564
29. Miller AP, Feng W, Xing D, Feng W, Weathington NM, Blalock JE, Chen YF, Oparil S 2004 Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteries. Circulation 110:1664-1669
30. Zaidi SH, You XM, Ciura S, Husain M, Rabinovitch M 2002 Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension. Circulation 105:516-521
31. Crossno JT Jr, Garat CV, Reusch JE, Morris KG, Dempsey EC, McMurtry IF, Stenmark KR, Klemm DJ 2007 Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling. Am J Physiol Lung Cell Mol Physiol 292:L885-L897
32. Rabinovitch M, Gamble WJ, Miettinen OS, Reid L 1981 Age and sex influence on pulmonary hypertension of chronic hypoxia and on recovery. Am J Physiol 240:H62-H72
33. Gebb SA, Fox K, Vaughn J, McKean D, Jones PL 2005 Fetal oxygen tension promotes tenascin-C-dependent lung branching morphogenesis. Dev Dyn 234:1-10
34. Kheradmand F, Rishi K, Werb Z 2002 Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2. J Cell Sci 115:839-848
35. Atkinson JJ, Holmbeck K, Yamada S, Birkedal-Hansen H, Parks WC, Senior RM 2005 Membrane-type 1 matrix metalloproteinase is required for normal alveolar development. Dev Dyn 232:1079-1090
36. Caterina JJ, Yamada S, Caterina NC, Longenecker G, Holmback K, Shi J, Yermovsky AE, Engler JA, Birkedal-Hansen H 2000 Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2 (Timp-2) gene alters proMMP-2 activation. J Biol Chem 275:26416-26422
37. Coalson JJ 2003 Pathology of new bronchopulmonary dysplasia. Semin Neonatol 8:73-81
38. Danan C, Jarreau PH, Franco ML, Dassieu G, Grillon C, Abd Alsamad I, Lafuma C, Harf A, Delacourt C 2002 Gelatinase activities in the airways of premature infants and development of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol 283:L1086-L1093