메뉴 건너뛰기




Volumn 20, Issue 11, 2014, Pages 3023-3032

Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern Cooperative Oncology Group E2303

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CARBOPLATIN; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN NRAS; PROTEIN P53; PROTEIN P85; PROTEIN PI3KP110A; RAS PROTEIN; RETINOBLASTOMA PROTEIN; SCATTER FACTOR RECEPTOR; SOMATOMEDIN C RECEPTOR; STAT3 PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MONOCLONAL ANTIBODY;

EID: 84901811387     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-0113     Document Type: Article
Times cited : (30)

References (36)
  • 2
    • 84875267472 scopus 로고    scopus 로고
    • Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): A randomised phase 3 trial
    • Haddad R, O'Neill A, Rabinowits G, Tishler R, Khuri F, Adkins D, et al. Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial. Lancet Oncol 2013;14:257-64.
    • (2013) Lancet Oncol , vol.14 , pp. 257-264
    • Haddad, R.1    O'Neill, A.2    Rabinowits, G.3    Tishler, R.4    Khuri, F.5    Adkins, D.6
  • 3
    • 79151485327 scopus 로고    scopus 로고
    • Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: Long-term results of the TAX 324 randomised phase 3 trial
    • Lorch JH, Goloubeva O, Haddad RI, Cullen K, Sarlis N, Tishler R, et al. Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. Lancet Oncol 2011;12:153-9.
    • (2011) Lancet Oncol , vol.12 , pp. 153-159
    • Lorch, J.H.1    Goloubeva, O.2    Haddad, R.I.3    Cullen, K.4    Sarlis, N.5    Tishler, R.6
  • 6
    • 0037115674 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
    • Ang KK, Berkey BA, Tu X, Zhang HZ, Katz R, Hammond EH, et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002;62:7350-6. (Pubitemid 36025259)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7350-7356
    • Ang, K.K.1    Berkey, B.A.2    Tu, X.3    Zhang, H.-Z.4    Katz, R.5    Hammond, E.H.6    Fu, K.K.7    Milas, L.8
  • 7
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • Herbst RS, Kim ES, Harari PM. IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer. Expert Opin Biol Ther 2001;1:719-32. (Pubitemid 33769082)
    • (2001) Expert Opinion on Biological Therapy , vol.1 , Issue.4 , pp. 719-732
    • Herbst, R.S.1    Kim, E.S.2    Harari, P.M.3
  • 11
    • 33748188459 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology in head and neck cancer
    • DOI 10.1200/JCO.2005.04.8306
    • Kalyankrishna S, Grandis JR. Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 2006;24:2666-72. (Pubitemid 46622088)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.17 , pp. 2666-2672
    • Kalyankrishna, S.1    Grandis, J.R.2
  • 12
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • DOI 10.1038/sj.onc.1210414, PII 1210414
    • Meloche S, Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007;26:3227-39. (Pubitemid 46763017)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 13
    • 77951744287 scopus 로고    scopus 로고
    • New strategies in head and neck cancer: Understanding resistance to epidermal growth factor receptor inhibitors
    • Chen LF, Cohen EE, Grandis JR. New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors. Clin Cancer Res 2010;16:2489-95.
    • (2010) Clin Cancer Res , vol.16 , pp. 2489-2495
    • Chen, L.F.1    Cohen, E.E.2    Grandis, J.R.3
  • 16
    • 4344680669 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells
    • DOI 10.1074/jbc.M405123200
    • Lorch JH, Klessner J, Park JK, Getsios S, Wu YL, Stack MS, et al. Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells. J Biol Chem 2004;279:37191-200. (Pubitemid 39129070)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.35 , pp. 37191-37200
    • Lorch, J.H.1    Klessner, J.2    Park, J.K.3    Getsios, S.4    Wu, Y.L.5    Stack, M.S.6    Green, K.J.7
  • 18
    • 78650842574 scopus 로고    scopus 로고
    • Mechanisms underlying resistance to cetuximab in the HNSCC cell line: Role of AKT inhibition in bypassing this resistance
    • Rebucci M, Peixoto P, Dewitte A, Wattez N, De Nuncques MA, Rezvoy N, et al. Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance. Int J Oncol 2011;38:189-200.
    • (2011) Int J Oncol , vol.38 , pp. 189-200
    • Rebucci, M.1    Peixoto, P.2    Dewitte, A.3    Wattez, N.4    De Nuncques, M.A.5    Rezvoy, N.6
  • 19
    • 0035418622 scopus 로고    scopus 로고
    • Activated extracellular signal-regulated kinases: Association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments
    • Albanell J, Codony-Servat J, Rojo F, Del Campo JM, Sauleda S, Anido J, et al. Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments. Cancer Res 2001;61:6500-10. (Pubitemid 32783257)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6500-6510
    • Albanell, J.1    Codony-Servat, J.2    Rojo, F.3    Del, C.J.M.4    Sauleda, S.5    Anido, J.6    Raspall, G.7    Giralt, J.8    Rosello, J.9    Nicholson, R.I.10    Mendelsohn, J.11    Baselga, J.12
  • 20
    • 84859872673 scopus 로고    scopus 로고
    • Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma
    • Wheeler S, Siwak DR, Chai R, LaValle C, Seethala RR, Wang L, et al. Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. Clin Cancer Res 2012;18:2278-89.
    • (2012) Clin Cancer Res , vol.18 , pp. 2278-2289
    • Wheeler, S.1    Siwak, D.R.2    Chai, R.3    LaValle, C.4    Seethala, R.R.5    Wang, L.6
  • 21
    • 66149135285 scopus 로고    scopus 로고
    • The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma
    • Seiwert TY, Jagadeeswaran R, Faoro L, Janamanchi V, Nallasura V, El Dinali M, et al. The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma. Cancer Res 2009;69:3021-31.
    • (2009) Cancer Res , vol.69 , pp. 3021-3031
    • Seiwert, T.Y.1    Jagadeeswaran, R.2    Faoro, L.3    Janamanchi, V.4    Nallasura, V.5    El Dinali, M.6
  • 22
    • 81255136527 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma
    • Chung CH, Pohlmann PR, Rothenberg ML, Burkey BB, Parker J, Palka K, et al. Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma. Head Neck 2011;33:1804-8.
    • (2011) Head Neck , vol.33 , pp. 1804-1808
    • Chung, C.H.1    Pohlmann, P.R.2    Rothenberg, M.L.3    Burkey, B.B.4    Parker, J.5    Palka, K.6
  • 23
    • 65549125308 scopus 로고    scopus 로고
    • Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor
    • Dudek AZ, Lesniewski-Kmak K, Shehadeh NJ, Pandey ON, Franklin M, Kratzke RA, et al. Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor. Br J Cancer 2009;100:1379-84.
    • (2009) Br J Cancer , vol.100 , pp. 1379-1384
    • Dudek, A.Z.1    Lesniewski-Kmak, K.2    Shehadeh, N.J.3    Pandey, O.N.4    Franklin, M.5    Kratzke, R.A.6
  • 24
    • 78649972439 scopus 로고    scopus 로고
    • Cellular response to cetuximab in PTEN-silenced head and neck squamous cell carcinoma cell line
    • Mriouah J, Boura C, Pinel S, Chretien AS, Fifre A, Merlin JL, et al. Cellular response to cetuximab in PTEN-silenced head and neck squamous cell carcinoma cell line. Int J Oncol 2010;37:1555-63.
    • (2010) Int J Oncol , vol.37 , pp. 1555-1563
    • Mriouah, J.1    Boura, C.2    Pinel, S.3    Chretien, A.S.4    Fifre, A.5    Merlin, J.L.6
  • 25
    • 0036852721 scopus 로고    scopus 로고
    • Automated subcellular localization and quantification of protein expression in tissue microarrays
    • DOI 10.1038/nm791
    • Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med 2002;8:1323-7. (Pubitemid 35373567)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1323-1327
    • Camp, R.L.1    Chung, G.G.2    Rimm, D.L.3
  • 26
    • 84901779304 scopus 로고    scopus 로고
    • Activity of cetuximab (C) in head and neck squamous cell carcinoma (HNSCC) patients (pts) with PTEN loss or PIK3CA mutation treated on E5397, a phase III trial of cisplatin (CDDP) with placebo (P) or C
    • abstr 6028
    • Burtness BA J-WL, Yang Donghua, Zhu Fang, Garcia Joaquin J, Forastiere Arlene A, Chung Christine H. Activity of cetuximab (C) in head and neck squamous cell carcinoma (HNSCC) patients (pts) with PTEN loss or PIK3CA mutation treated on E5397, a phase III trial of cisplatin (CDDP) with placebo (P) or C. J Clin Oncol 31, 2013 (suppl; abstr 6028).
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL.
    • Burtness, B.A.1    L, J.-W.2    Yang, D.3    Zhu, F.4    Garcia, J.J.5    Forastiere, A.A.6    Chung, C.H.7
  • 27
    • 0036212767 scopus 로고    scopus 로고
    • Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors
    • DOI 10.1038/nbt0402-370
    • Schoeberl B, Eichler-Jonsson C, Gilles ED, Muller G. Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors. Nat Biotechnol 2002;20:370-5. (Pubitemid 34286330)
    • (2002) Nature Biotechnology , vol.20 , Issue.4 , pp. 370-375
    • Schoeberl, B.1    Eichler-Jonsson, C.2    Gilles, E.D.3    Muller, G.4
  • 28
    • 77950977952 scopus 로고    scopus 로고
    • Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis
    • Pectasides E, Egloff AM, Sasaki C, Kountourakis P, Burtness B, Fountzilas G, et al. Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis. Clin Cancer Res 2010;16:2427-34.
    • (2010) Clin Cancer Res , vol.16 , pp. 2427-2434
    • Pectasides, E.1    Egloff, A.M.2    Sasaki, C.3    Kountourakis, P.4    Burtness, B.5    Fountzilas, G.6
  • 29
    • 77949464718 scopus 로고    scopus 로고
    • From basic research to clinical development of MEK1/2 inhibitors for cancer therapy
    • Fremin C, Meloche S. From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. J Hematol Oncol 2010;3:8.
    • (2010) J Hematol Oncol , vol.3 , pp. 8
    • Fremin, C.1    Meloche, S.2
  • 30
    • 42649137241 scopus 로고    scopus 로고
    • Mechanisms of disease: Epithelial-mesenchymal transition - Does cellular plasticity fuel neoplastic progression?
    • DOI 10.1038/ncponc1089, PII NCPONC1089
    • Turley EA, Veiseh M, Radisky DC, Bissell MJ. Mechanisms of disease: epithelial-mesenchymal transition-does cellular plasticity fuel neoplastic progression? Nat Clin Pract Oncol 2008;5:280-90. (Pubitemid 351594144)
    • (2008) Nature Clinical Practice Oncology , vol.5 , Issue.5 , pp. 280-290
    • Turley, E.A.1    Veiseh, M.2    Radisky, D.C.3    Bissell, M.J.4
  • 31
    • 70449651958 scopus 로고    scopus 로고
    • Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway
    • Hoover AC, Strand GL, Nowicki PN, Anderson ME, Vermeer PD, Klingelhutz AJ, et al. Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway. Oncogene 2009;28:3960-70.
    • (2009) Oncogene , vol.28 , pp. 3960-3970
    • Hoover, A.C.1    Strand, G.L.2    Nowicki, P.N.3    Anderson, M.E.4    Vermeer, P.D.5    Klingelhutz, A.J.6
  • 33
    • 79959260166 scopus 로고    scopus 로고
    • Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas
    • Basu D, Montone KT, Wang LP, Gimotty PA, Hammond R, Diehl JA, et al. Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell Cycle 2011;10:2008-16.
    • (2011) Cell Cycle , vol.10 , pp. 2008-2016
    • Basu, D.1    Montone, K.T.2    Wang, L.P.3    Gimotty, P.A.4    Hammond, R.5    Diehl, J.A.6
  • 34
    • 0033635157 scopus 로고    scopus 로고
    • Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
    • Pacold ME, Suire S, Perisic O, Lara-Gonzalez S, Davis CT, Walker EH, et al. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma. Cell 2000;103:931-43.
    • (2000) Cell , vol.103 , pp. 931-943
    • Pacold, M.E.1    Suire, S.2    Perisic, O.3    Lara-Gonzalez, S.4    Davis, C.T.5    Walker, E.H.6
  • 35
    • 30044446979 scopus 로고    scopus 로고
    • Quantitative model of Ras-phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly
    • DOI 10.1042/BJ20051022
    • Kaur H, Park CS, Lewis JM, Haugh JM. Quantitative model of Ras-phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly. Biochem J 2006;393:235-43. (Pubitemid 43049320)
    • (2006) Biochemical Journal , vol.393 , Issue.1 , pp. 235-243
    • Kaur, H.1    Park, C.S.2    Lewis, J.M.3    Haugh, J.M.4
  • 36
    • 84879936681 scopus 로고    scopus 로고
    • Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway
    • Holzinger D, Flechtenmacher C, Henfling N, Kaden I, Grabe N, Lahrmann B, et al. Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway. Int J Cancer 2013;133:1389-99.
    • (2013) Int J Cancer , vol.133 , pp. 1389-1399
    • Holzinger, D.1    Flechtenmacher, C.2    Henfling, N.3    Kaden, I.4    Grabe, N.5    Lahrmann, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.