-
1
-
-
0027340385
-
Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts
-
Alblas, J., E.J. van Corven, P.L. Hordijk, G. Milligan, and W.H. Moolenaar. 1993. Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts. J. Biol. Chem. 268:22235-22238.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 22235-22238
-
-
Alblas, J.1
van Corven, E.J.2
Hordijk, P.L.3
Milligan, G.4
Moolenaar, W.H.5
-
2
-
-
73949099966
-
Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors
-
Aoki, K., and M. Matsuda. 2009. Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors. Nat. Protoc. 4: 1623-1631. http://dx.doi.org/10.1038/nprot.2009.175.
-
(2009)
Nat. Protoc
, vol.4
, pp. 1623-1631
-
-
Aoki, K.1
Matsuda, M.2
-
3
-
-
0030176170
-
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: A possible pathway for inhibition of the respiratory burst
-
Bengis-Garber, C., and N. Gruener. 1996. Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: A possible pathway for inhibition of the respiratory burst. Cell. Signal. 8:291-296. http://dx.doi.org/10.1016/0898-6568(96)00052-6.
-
(1996)
Cell. Signal
, vol.8
, pp. 291-296
-
-
Bengis-Garber, C.1
Gruener, N.2
-
4
-
-
0030922428
-
Inhibition of PAF-induced expression of CD11b and shedding of L-selectin on human neutrophils and eosinophils by the type IV selective PDE inhibitor, rolipram
-
Berends, C., B. Dijkhuizen, J.G. de Monchy, A.E. Dubois, J. Gerritsen, and H.F. Kauffman. 1997. Inhibition of PAF-induced expression of CD11b and shedding of L-selectin on human neutrophils and eosinophils by the type IV selective PDE inhibitor, rolipram. Eur. Respir. J. 10:1000-1007. http://dx.doi.org/10.1183/09031936.97.10051000.
-
(1997)
Eur. Respir. J
, vol.10
, pp. 1000-1007
-
-
Berends, C.1
Dijkhuizen, B.2
de Monchy, J.G.3
Dubois, A.E.4
Gerritsen, J.5
Kauffman, H.F.6
-
5
-
-
0027244454
-
Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans
-
Bjarnason, I., J. Hayllar, A.J. MacPherson, and A.S. Russell. 1993. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology. 104:1832-1847.
-
(1993)
Gastroenterology
, vol.104
, pp. 1832-1847
-
-
Bjarnason, I.1
Hayllar, J.2
MacPherson, A.J.3
Russell, A.S.4
-
6
-
-
78649375771
-
Neutrophils, from marrow to microbes
-
Borregaard, N. 2010. Neutrophils, from marrow to microbes. Immunity. 33:657-670. http://dx.doi.org/10.1016/j.immuni.2010.11.011.
-
(2010)
Immunity
, vol.33
, pp. 657-670
-
-
Borregaard, N.1
-
7
-
-
0032128337
-
Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase-dependent pathway
-
Capodici, C., M.H. Pillinger, G. Han, M.R. Philips, and G. Weissmann. 1998. Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase-dependent pathway. J. Clin. Invest. 102:165-175. http://dx.doi.org/10.1172/JCI592.
-
(1998)
J. Clin. Invest
, vol.102
, pp. 165-175
-
-
Capodici, C.1
Pillinger, M.H.2
Han, G.3
Philips, M.R.4
Weissmann, G.5
-
8
-
-
0028800523
-
Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators
-
Derian, C.K., R.J. Santulli, P.E. Rao, H.F. Solomon, and J.A. Barrett. 1995. Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators. J. Immunol. 154:308-317.
-
(1995)
J. Immunol
, vol.154
, pp. 308-317
-
-
Derian, C.K.1
Santulli, R.J.2
Rao, P.E.3
Solomon, H.F.4
Barrett, J.A.5
-
9
-
-
0033885778
-
Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study
-
Felder, J.B., B.I. Korelitz, R. Rajapakse, S. Schwarz, A.P. Horatagis, and G. Gleim. 2000. Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study. Am. J. Gastroenterol. 95:1949-1954. http://dx.doi.org/10.1111/j.1572-0241.2000.02262.x.
-
(2000)
Am. J. Gastroenterol
, vol.95
, pp. 1949-1954
-
-
Felder, J.B.1
Korelitz, B.I.2
Rajapakse, R.3
Schwarz, S.4
Horatagis, A.P.5
Gleim, G.6
-
10
-
-
0037809229
-
2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases
-
2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases. J. Biol. Chem. 278:12151-12156. http:// dx.doi.org/10.1074/jbc.M212665200.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 12151-12156
-
-
Fujino, H.1
Xu, W.2
Regan, J.W.3
-
11
-
-
84862976472
-
A decade of imaging cellular motility and interaction dynamics in the immune system
-
Germain, R.N., E.A. Robey, and M.D. Cahalan. 2012. A decade of imaging cellular motility and interaction dynamics in the immune system. Science. 336:1676-1681. http://dx.doi.org/10.1126/science.1221063.
-
(2012)
Science
, vol.336
, pp. 1676-1681
-
-
Germain, R.N.1
Robey, E.A.2
Cahalan, M.D.3
-
12
-
-
0028124505
-
Mechanism of inhibition of Raf-1 by protein kinase A
-
Häfner, S., H.S. Adler, H. Mischak, P. Janosch, G. Heidecker, A. Wolfman, S. Pippig, M. Lohse, M. Ueffing, and W. Kolch. 1994. Mechanism of inhibition of Raf-1 by protein kinase A. Mol. Cell. Biol. 14:6696-6703.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 6696-6703
-
-
Häfner, S.1
Adler, H.S.2
Mischak, H.3
Janosch, P.4
Heidecker, G.5
Wolfman, A.6
Pippig, S.7
Lohse, M.8
Ueffing, M.9
Kolch, W.10
-
13
-
-
4444262310
-
Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation
-
Hata, A.N., and R.M. Breyer. 2004. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol. Ther. 103:147-166. http://dx.doi.org/10.1016/j.pharmthera.2004.06.003.
-
(2004)
Pharmacol. Ther
, vol.103
, pp. 147-166
-
-
Hata, A.N.1
Breyer, R.M.2
-
14
-
-
0037078334
-
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients
-
Heit, B., S. Tavener, E. Raharjo, and P. Kubes. 2002. An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J. Cell Biol. 159:91-102. http://dx.doi.org/10.1083/jcb.200202114.
-
(2002)
J. Cell Biol
, vol.159
, pp. 91-102
-
-
Heit, B.1
Tavener, S.2
Raharjo, E.3
Kubes, P.4
-
15
-
-
0027432825
-
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1
-
Howe, L.R., and C.J. Marshall. 1993. Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1. J. Biol. Chem. 268:20717-20720.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 20717-20720
-
-
Howe, L.R.1
Marshall, C.J.2
-
16
-
-
0036221333
-
4 suppresses colitis, mucosal damage and CD4 cell activation in the gut
-
4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. J. Clin. Invest. 109:883-893. http://dx.doi.org/ 10.1172/JCI0214459.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 883-893
-
-
Kabashima, K.1
Saji, T.2
Murata, T.3
Nagamachi, M.4
Matsuoka, T.5
Segi, E.6
Tsuboi, K.7
Sugimoto, Y.8
Kobayashi, T.9
Miyachi, Y.10
-
17
-
-
84855361145
-
2
-
2. J. Immunol. 188:21-28. http://dx.doi.org/10.4049/jimmunol.1101029.
-
(2012)
J. Immunol
, vol.188
, pp. 21-28
-
-
Kalinski, P.1
-
18
-
-
84862304850
-
Live imaging of protein kinase activities in transgenic mice expressing FRET biosensors
-
Kamioka, Y., K. Sumiyama, R. Mizuno, Y. Sakai, E. Hirata, E. Kiyokawa, and M. Matsuda. 2012. Live imaging of protein kinase activities in transgenic mice expressing FRET biosensors. Cell Struct. Funct. 37:65-73. http://dx.doi.org/10.1247/csf.11045.
-
(2012)
Cell Struct. Funct
, vol.37
, pp. 65-73
-
-
Kamioka, Y.1
Sumiyama, K.2
Mizuno, R.3
Sakai, Y.4
Hirata, E.5
Kiyokawa, E.6
Matsuda, M.7
-
19
-
-
84875442814
-
Neutrophil recruitment and function in health and inflammation
-
Kolaczkowska, E., and P. Kubes. 2013. Neutrophil recruitment and function in health and inflammation. Nat. Rev. Immunol. 13:159-175. http:// dx.doi.org/10.1038/nri3399.
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 159-175
-
-
Kolaczkowska, E.1
Kubes, P.2
-
20
-
-
0142148323
-
In vivo impairment of neutrophil recruitment during lentivirus infection
-
Kubes, P., B. Heit, G. van Marle, J.B. Johnston, D. Knight, A. Khan, and C. Power. 2003. In vivo impairment of neutrophil recruitment during lentivirus infection. J. Immunol. 171:4801-4808. http://dx.doi.org/10.4049/ jimmunol.171.9.4801.
-
(2003)
J. Immunol
, vol.171
, pp. 4801-4808
-
-
Kubes, P.1
Heit, B.2
van Marle, G.3
Johnston, J.B.4
Knight, D.5
Khan, A.6
Power, C.7
-
21
-
-
84862785325
-
Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases
-
Liu, X., B. Ma, A.B. Malik, H. Tang, T. Yang, B. Sun, G. Wang, R.D. Minshall, Y. Li, Y. Zhao, et al. 2012. Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nat. Immunol. 13:457-464. http://dx.doi.org/10.1038/ni.2258.
-
(2012)
Nat. Immunol
, vol.13
, pp. 457-464
-
-
Liu, X.1
Ma, B.2
Malik, A.B.3
Tang, H.4
Yang, T.5
Sun, B.6
Wang, G.7
Minshall, R.D.8
Li, Y.9
Zhao, Y.10
-
23
-
-
79955761501
-
Intravital imaging of phagocyte recruitment
-
Megens, R.T.A., K. Kemmerich, J. Pyta, C. Weber, and O. Soehnlein. 2011. Intravital imaging of phagocyte recruitment. Thromb. Haemost. 105:802-810. http://dx.doi.org/10.1160/TH10-11-0735.
-
(2011)
Thromb. Haemost
, vol.105
, pp. 802-810
-
-
Megens, R.T.A.1
Kemmerich, K.2
Pyta, J.3
Weber, C.4
Soehnlein, O.5
-
25
-
-
79958134859
-
Prostanoids and inflammation: a new concept arising from receptor knockout mice
-
Narumiya, S. 2009. Prostanoids and inflammation: a new concept arising from receptor knockout mice. J. Mol. Med. 87:1015-1022. http://dx.doi.org/ 10.1007/s00109-009-0500-1.
-
(2009)
J. Mol. Med
, vol.87
, pp. 1015-1022
-
-
Narumiya, S.1
-
26
-
-
0032823306
-
Prostanoid receptors: structures, properties, and functions
-
Narumiya, S., Y. Sugimoto, and F. Ushikubi. 1999. Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79:1193-1226.
-
(1999)
Physiol. Rev
, vol.79
, pp. 1193-1226
-
-
Narumiya, S.1
Sugimoto, Y.2
Ushikubi, F.3
-
27
-
-
0029661961
-
4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist
-
4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist. Mol. Pharmacol. 50:1031-1037.
-
(1996)
Mol. Pharmacol
, vol.50
, pp. 1031-1037
-
-
Nishigaki, N.1
Negishi, M.2
Ichikawa, A.3
-
28
-
-
81255188938
-
The neutrophil in vascular inflammation
-
Phillipson, M., and P. Kubes. 2011. The neutrophil in vascular inflammation. Nat. Med. 17:1381-1390. http://dx.doi.org/10.1038/nm.2514.
-
(2011)
Nat. Med
, vol.17
, pp. 1381-1390
-
-
Phillipson, M.1
Kubes, P.2
-
29
-
-
0029888085
-
Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion
-
Pillinger, M.H., A.S. Feoktistov, C. Capodici, B. Solitar, J. Levy, T.T. Oei, and M.R. Philips. 1996. Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion. J. Biol. Chem. 271:12049-12056. http://dx.doi.org/10.1074/jbc.271.20.12049.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 12049-12056
-
-
Pillinger, M.H.1
Feoktistov, A.S.2
Capodici, C.3
Solitar, B.4
Levy, J.5
Oei, T.T.6
Philips, M.R.7
-
30
-
-
0032564358
-
Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion
-
Pillinger, M.H., C. Capodici, P. Rosenthal, N. Kheterpal, S. Hanft, M.R. Philips, and G. Weissmann. 1998. Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion. Proc. Natl. Acad. Sci. USA. 95:14540-14545. http://dx.doi.org/10.1073/pnas.95.24.14540.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14540-14545
-
-
Pillinger, M.H.1
Capodici, C.2
Rosenthal, P.3
Kheterpal, N.4
Hanft, S.5
Philips, M.R.6
Weissmann, G.7
-
32
-
-
84856059736
-
Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking
-
Sanz, M.J., and P. Kubes. 2012. Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking. Eur. J. Immunol. 42:278-283. http:// dx.doi.org/10.1002/eji.201142231.
-
(2012)
Eur. J. Immunol
, vol.42
, pp. 278-283
-
-
Sanz, M.J.1
Kubes, P.2
-
33
-
-
0036113986
-
Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/ CD18 and CD11b/CD18 co-dependent
-
Stadnyk, A.W., C. Dollard, T.B. Issekutz, and A.C. Issekutz. 2002. Neutrophil migration into indomethacin induced rat small intestinal injury is CD11a/ CD18 and CD11b/CD18 co-dependent. Gut. 50:629-635. http://dx.doi.org/10.1136/gut.50.5.629.
-
(2002)
Gut
, vol.50
, pp. 629-635
-
-
Stadnyk, A.W.1
Dollard, C.2
Issekutz, T.B.3
Issekutz, A.C.4
-
34
-
-
0030963439
-
cAMP activates MAP kinase and Elk-1 through a B-Raf-and Rap1-dependent pathway
-
Vossler, M.R., H. Yao, R.D. York, M.G. Pan, C.S. Rim, and P.J. Stork. 1997. cAMP activates MAP kinase and Elk-1 through a B-Raf-and Rap1-dependent pathway. Cell. 89:73-82. http://dx.doi.org/10.1016/ S0092-8674(00)80184-1.
-
(1997)
Cell
, vol.89
, pp. 73-82
-
-
Vossler, M.R.1
Yao, H.2
York, R.D.3
Pan, M.G.4
Rim, C.S.5
Stork, P.J.6
-
35
-
-
82955184551
-
NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies
-
Wallace, J.L. 2012. NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies. Br. J. Pharmacol. 165:67-74. http://dx.doi.org/10.1111/j.1476-5381.2011.01509.x.
-
(2012)
Br. J. Pharmacol
, vol.165
, pp. 67-74
-
-
Wallace, J.L.1
-
36
-
-
0025078185
-
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process
-
Wallace, J.L., C.M. Keenan, and D.N. Granger. 1990. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am. J. Physiol. 259:G462-G467.
-
(1990)
Am. J. Physiol
, vol.259
-
-
Wallace, J.L.1
Keenan, C.M.2
Granger, D.N.3
-
37
-
-
0027240231
-
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
-
Winitz, S., M. Russell, N.X. Qian, A. Gardner, L. Dwyer, and G.L. Johnson. 1993. Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J. Biol. Chem. 268:19196-19199.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 19196-19199
-
-
Winitz, S.1
Russell, M.2
Qian, N.X.3
Gardner, A.4
Dwyer, L.5
Johnson, G.L.6
-
38
-
-
0034638635
-
4, differentially modulate TNF-α and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils
-
4, differentially modulate TNF-α and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. Biochem. Biophys. Res. Commun. 278:224-228. http://dx.doi.org/10.1006/bbrc.2000.3779.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.278
, pp. 224-228
-
-
Yamane, H.1
Sugimoto, Y.2
Tanaka, S.3
Ichikawa, A.4
-
39
-
-
0030976460
-
A Gprotein-coupled receptor for leukotriene B4 that mediates chemotaxis
-
Yokomizo, T., T. Izumi, K. Chang, Y. Takuwa, and T. Shimizu. 1997. A Gprotein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 387:620-624. http://dx.doi.org/10.1038/42506.
-
(1997)
Nature
, vol.387
, pp. 620-624
-
-
Yokomizo, T.1
Izumi, T.2
Chang, K.3
Takuwa, Y.4
Shimizu, T.5
-
40
-
-
36349025935
-
Gαi2 is required for chemokine-induced neutrophil arrest
-
Zarbock, A., T.L. Deem, T.L. Burcin, and K. Ley. 2007. Gαi2 is required for chemokine-induced neutrophil arrest. Blood. 110:3773-3779. http://dx.doi.org/10.1182/blood-2007-06-094565.
-
(2007)
Blood
, vol.110
, pp. 3773-3779
-
-
Zarbock, A.1
Deem, T.L.2
Burcin, T.L.3
Ley, K.4
|