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Volumn 42, Issue 3, 2014, Pages 605-618

Blood pressure lowering effect of korea ginseng derived ginseol K-g1

Author keywords

Blood Pressure; Clinical Trial; Ginseng; Ginseol K g1

Indexed keywords

GINSENG EXTRACT; GINSENOSIDE; GINSEOL K G1; PROTOPANAXATRIOL; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; GINSEOL K-G1;

EID: 84901779583     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X14500396     Document Type: Article
Times cited : (29)

References (25)
  • 1
    • 84876566583 scopus 로고    scopus 로고
    • Panax ginseng extract rich in ginsenoside protopanaxatriol offers combinatorial effects in nitric oxide production via multiple signaling pathways
    • Ahn, H.Y., S.Y. Hong, J.Y. Kim and O. Kwon. Panax ginseng extract rich in ginsenoside protopanaxatriol offers combinatorial effects in nitric oxide production via multiple signaling pathways. Springerplus 2: 96, 2013.
    • (2013) Springerplus , vol.2 , Issue.96
    • Ahn, H.Y.1    Hong, S.Y.2    Kim, J.Y.3    Kwon, O.4
  • 2
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: Multiple constituents and multiple actions
    • Attele, A.S., J.A. Wu and C.S. Yuan. Ginseng pharmacology: Multiple constituents and multiple actions. Biochem. Pharmacol. 58: 1685-1693, 1999.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 4
    • 50349101675 scopus 로고    scopus 로고
    • Ginsenosides chemistry, biosyn
    • thesis, analysis, and potential health effects
    • Christensen, L.P. Ginsenosides chemistry, biosynthesis, analysis, and potential health effects. Adv. Food Nutr. Res. 55: 1-99, 2009.
    • (2009) Adv. Food Nutr. Res. , vol.55 , pp. 1-99
    • Christensen, L.P.1
  • 5
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: A nitric oxide link?
    • DOI 10.1016/S0006-2952(97)00193-7, PII S0006295297001937
    • Gillis, C.N. Panax ginseng pharmacology: A nitric oxide link? Biochem. Pharmacol. 54: 1-8, 1997. (Pubitemid 27353216)
    • (1997) Biochemical Pharmacology , vol.54 , Issue.1 , pp. 1-8
    • Gillis, C.N.1
  • 6
    • 79952256605 scopus 로고    scopus 로고
    • Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation
    • Guo, J., X.T. Gan, J.V. Haist, V. Rajapurohitam, A. Zeidan, N.S. Faruq and M. Karmazyn. Ginseng inhibits cardiomyocyte hypertrophy and heart failure via NHE-1 inhibition and attenuation of calcineurin activation. Circ. Heart Fail. 4: 79-88, 2011.
    • (2011) Circ. Heart Fail. , vol.4 , pp. 79-88
    • Guo, J.1    Gan, X.T.2    Haist, J.V.3    Rajapurohitam, V.4    Zeidan, A.5    Faruq, N.S.6    Karmazyn, M.7
  • 8
    • 84859129536 scopus 로고    scopus 로고
    • Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase
    • Hong, S.Y., J.Y. Kim, H.Y. Ahn, J.H. Shin and O. Kwon. Panax ginseng extract rich in ginsenoside protopanaxatriol attenuates blood pressure elevation in spontaneously hypertensive rats by affecting the Akt-dependent phosphorylation of endothelial nitric oxide synthase. J. Agric. Food Chem. 60: 3086-3091, 2012.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 3086-3091
    • Hong, S.Y.1    Kim, J.Y.2    Ahn, H.Y.3    Shin, J.H.4    Kwon, O.5
  • 10
    • 77951113474 scopus 로고    scopus 로고
    • Effects of Korean red ginseng (Panax ginseng CA Mayer) and its isolated ginsenosides and polysaccharides on arterial stiffness in healthy individuals
    • Jovanovski, E., A. Jenkins, A.G. Dias, V. Peeva, J. Sievenpiper, J.T. Arnason, D. Rahelic, R.G. Josse and V. Vuksan. Effects of Korean red ginseng (Panax ginseng C.A. Mayer) and its isolated ginsenosides and polysaccharides on arterial stiffness in healthy individuals. Am. J. Hypertens. 23: 469-472, 2010.
    • (2010) Am. J. Hypertens. , vol.23 , pp. 469-472
    • Jovanovski, E.1    Jenkins, A.2    Dias, A.G.3    Peeva, V.4    Sievenpiper, J.5    Arnason, J.T.6    Rahelic, D.7    Josse, R.G.8    Vuksan, V.9
  • 11
    • 0016611511 scopus 로고
    • Chemico-pharmacological studies on saponins of Panax ginseng C A Meyer i Chemical part
    • Kaku, T., T. Miyata, T. Uruno, I. Sako and A. Kinoshita. Chemico-pharmacological studies on saponins of Panax ginseng C. A. Meyer. I. Chemical part. Arzneimittel-Forschung 25: 343-347, 1975.
    • (1975) Arzneimittel-Forschung , vol.25 , pp. 343-347
    • Kaku, T.1    Miyata, T.2    Uruno, T.3    Sako, I.4    Kinoshita, A.5
  • 12
    • 0028914837 scopus 로고
    • Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta
    • Kang, S.Y., V.B. Schini-Kerth and N.D. Kim. Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta. Life Sci. 56: 1577-1586, 1995.
    • (1995) Life Sci. , vol.56 , pp. 1577-1586
    • Kang, S.Y.1    Schini-Kerth, V.B.2    Kim, N.D.3
  • 13
    • 80053953131 scopus 로고    scopus 로고
    • Therapeutic potential of Ginseng in the management of cardiovascular disorders
    • Karmazyn, M., M. Moey and X.T. Gan. Therapeutic potential of Ginseng in the management of cardiovascular disorders. Drugs 71: 1989-2008, 2011.
    • (2011) Drugs , vol.71 , pp. 1989-2008
    • Karmazyn, M.1    Moey, M.2    Gan, X.T.3
  • 14
    • 0242492625 scopus 로고    scopus 로고
    • Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase
    • Kim, N.D., E.M. Kim, K.W. Kang, M.K. Cho, S.Y. Choi and S.G. Kim. Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase. Br. J. Pharmacol. 140: 661-670, 2003.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 661-670
    • Kim, N.D.1    Kim, E.M.2    Kang, K.W.3    Cho, M.K.4    Choi, S.Y.5    Kim, S.G.6
  • 15
    • 33846013596 scopus 로고    scopus 로고
    • Ginsenoside-Rg1 induces vascular endothelial growth factor expression through the glucocorticoid receptor-related phosphatidylinositol 3-kinase/Akt and beta-catenin/T-cell factor-dependent pathway in human endothelial cells
    • Leung, K.W., Y.L. Pon, R.N. Wong and A.S. Wong. Ginsenoside-Rg1 induces vascular endothelial growth factor expression through the glucocorticoid receptor-related phosphatidylinositol 3-kinase/Akt and beta-catenin/T-cell factor-dependent pathway in human endothelial cells. J. Biol. Chem. 281: 36280-36288, 2006.
    • (2006) J. Biol. Chem. , vol.281 , pp. 36280-36288
    • Leung, K.W.1    Pon, Y.L.2    Wong, R.N.3    Wong, A.S.4
  • 16
    • 77953307436 scopus 로고    scopus 로고
    • Pharmacology of ginsenosides: A literature review
    • Leung, K.W. and A.S. Wong. Pharmacology of ginsenosides: A literature review. Chin. Med. 5: 20, 2010.
    • (2010) Chin. Med. , vol.5 , Issue.20
    • Leung, K.W.1    Wong, A.S.2
  • 17
    • 0032501120 scopus 로고    scopus 로고
    • Herbal medicinals: Selected clinical considerations focusing on known or potential drug-herb interactions
    • Miller, L.G. Herbal medicinals: Selected clinical considerations focusing on known or potential drug-herb interactions. Arch. Intern. Med. 158: 2200-2211, 1998.
    • (1998) Arch. Intern. Med. , vol.158 , pp. 2200-2211
    • Miller, L.G.1
  • 18
    • 84868150736 scopus 로고    scopus 로고
    • Effects of Korean Red Ginseng on cardiovascular risks in subjects with metabolic syndrome: A double-blind randomized controlled study
    • Park, B.J., Y.J. Lee, H.R. Lee, D.H. Jung, H.Y. Na, H.B. Kim and J.Y. Shim. Effects of Korean Red Ginseng on cardiovascular risks in subjects with metabolic syndrome: A double-blind randomized controlled study. Kor. J. Fam. Med. 33: 190-196, 2012.
    • (2012) Kor. J. Fam. Med. , vol.33 , pp. 190-196
    • Park, B.J.1    Lee, Y.J.2    Lee, H.R.3    Jung, D.H.4    Na, H.Y.5    Kim, H.B.6    Shim, J.Y.7
  • 19
    • 13444255966 scopus 로고    scopus 로고
    • Recommendations for blood pressure measurement in humans and experimental animals part 1: Blood pressure measurement in humans: A statement for professionals from the subcommittee of professional and public education of the american heart association council on high blood pressure research
    • Pickering, T.G., J.E. Hall, L.J. Appel, B.E. Falkner, J. Graves, M.N. Hill, D.W. Jones, T. Kurtz, S.G. Sheps and E.J. Roccella. Recommendations for blood pressure measurement in humans and experimental animals. Part 1: Blood pressure measurement in humans: A statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation 111: 697-716, 2005.
    • (2005) Circulation , vol.111 , pp. 697-716
    • Pickering, T.G.1    Hall, J.E.2    Appel, L.J.3    Falkner, B.E.4    Graves, J.5    Hill, M.N.6    Jones, D.W.7    Kurtz, T.8    Sheps, S.G.9    Roccella, E.J.10
  • 20
    • 84876243620 scopus 로고    scopus 로고
    • Quality and risk of bias in Panax ginseng randomized controlled trials: A review
    • Shergis, J.L., A.L. Zhang, W. Zhou and C.C. Xue. Quality and risk of bias in Panax ginseng randomized controlled trials: A review. Am. J. Chin. Med. 41: 231-252, 2013.
    • (2013) Am. J. Chin. Med. , vol.41 , pp. 231-252
    • Shergis, J.L.1    Zhang, A.L.2    Zhou, W.3    Xue, C.C.4
  • 21
    • 0018921765 scopus 로고
    • Ginseng and high blood pressure
    • Siegel, R.K. Ginseng and high blood pressure. JAMA 243: 32, 1980.
    • (1980) JAMA , vol.243 , pp. 32
    • Siegel, R.K.1
  • 22
    • 23244447852 scopus 로고    scopus 로고
    • North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension
    • DOI 10.1161/01.HYP.0000173424.77483.1e
    • Stavro, P.M., M. Woo, T.F. Heim, L.A. Leiter and V. Vuksan. North American ginseng exerts a neutral effect on blood pressure in individuals with hypertension. Hypertens 46: 406-411, 2005. (Pubitemid 41099177)
    • (2005) Hypertension , vol.46 , Issue.2 , pp. 406-411
    • Stavro, P.M.1    Woo, M.2    Heim, T.F.3    Leiter, L.A.4    Vuksan, V.5
  • 23
    • 0033647591 scopus 로고    scopus 로고
    • Effects of red ginseng upon vascular endothelial function in patients with essential hypertension
    • Sung, J., K.H. Han, J.H. Zo, H.J. Park, C.H. Kim and B.H. Oh. Effects of red ginseng upon vascular endothelial function in patients with essential hypertension. Am. J. Chin. Med. 28: 205-216, 2000.
    • (2000) Am. J. Chin. Med. , vol.28 , pp. 205-216
    • Sung, J.1    Han, K.H.2    Zo, J.H.3    Park, H.J.4    Kim, C.H.5    Oh, B.H.6
  • 24
  • 25
    • 0035240033 scopus 로고    scopus 로고
    • Panax ginseng-A non-organ-specific cancer preventive?
    • Yun, T.K. Panax ginseng-A non-organ-specific cancer preventive? Lancet Oncol. 2: 49-55, 2001.
    • (2001) Lancet Oncol. , vol.2 , pp. 49-55
    • Yun, T.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.