Effects of cichoric acid extract from Echinacea purpurea on collagen-induced arthritis in rats

American Journal of Chinese Medicine

Volumn 42, Issue 3, 2014, Pages 679-692

  Jiang, Ling ^a   Li, Weizu ^b   Wang, Yuchan ^b   Zhang, Xiaosu ^a   Yu, Deqiang ^a   Yin, Yanyan ^b   Xie, Zhongwen ^a   Yuan, Yi ^a  

^a ANHUI AGRICULTURAL UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Cichoric Acid Extract; Collagen Induced Arthritis; Cox 2; Cytokines; Inflammation; NF B; Synovium Tissues

Indexed keywords

ANTIRHEUMATIC AGENT; CICHORIC ACID; COLLAGEN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CAFFEIC ACID DERIVATIVE; SOLUTION AND SOLUBILITY; SUCCINIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKLE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ECHINACEA PURPUREA; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; ORGAN WEIGHT; PAW EDEMA; PROTEIN EXPRESSION; RAT; SPLEEN; SYNOVIUM; THYMUS; WESTERN BLOTTING; ANIMAL; ARTHRITIS, EXPERIMENTAL; BLOOD; CHEMISTRY; DISEASE MODEL; ECHINACEA; ISOLATION AND PURIFICATION; KNEE; METABOLISM; ORAL DRUG ADMINISTRATION; PHYTOTHERAPY; SOLUTION AND SOLUBILITY; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CAFFEIC ACIDS; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE MODELS, ANIMAL; ECHINACEA; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-1BETA; KNEE JOINT; MALE; NF-KAPPA B; PHYTOTHERAPY; RATS; RATS, SPRAGUE-DAWLEY; SOLUTIONS; SUCCINATES; SYNOVIAL MEMBRANE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84901774077     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X1450044X     Document Type: Article

References (44)

1. Akarasereenont, P., Y.S. Bakhle, C. Thiemermann and J.R. Vane. Cytokine-mediated induction of cyclo-oxygenase-2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide. Br. J. Pharmacol. 115: 401-408, 1995.
2. Baldwin, A.S. The NF-kappa B and I kappa B proteins: New discoveries and insights. Ann. Rev. Immunol. 14: 649-683, 1996.
3. Barnes, J., L.A. Anderson, S. Gibbons and J.D. Phillipson. Echinacea species (Echinacea angustifolia (DC) Hell, Echinacea pallida (Nutt) Nutt., Echinacea purpurea (L) Moench): A review of their chemistry, pharmacology and clinical properties. J. Pharm. Pharmacol. 57: 929-954, 2005.
4. Barrett, B. Medicinal properties of Echinacea: A critical review. Phytomedicine 10(1): 66-86, 2003. (Pubitemid 36262210)
5. Bauer, R. and H. Wagner. Echinacea species as potential immunostimulatory drugs. In: H. Wagner, and N.R. Farnsworth (eds) Economic and Medicinal Plants Research. Academic Press, London, 1991, pp. 253-321.
6. Calvino, B., M.O. Bernard and D.L. Bars. Parallel clinical and behavioural studies of adjuvantinduced arthritis in the rats: Possible relationship with chronic pain. Behav. Brain Res. 24: 11-29, 1987.
7. Cha, H.S., K.S. Ahn, C.H. Jeon, J. Kim and E.M. Koh. Inhibitory effect of cyclo-oxygenase-2 inhibitor on the production of matrix metalloproteinases in rheumatoid fibroblast-like synoviocytes. Rheumatol. Int. 24: 207-211, 2004.
8. Chandrashekara, S., T. Anilkumar and S. Jamuna. Complementary and alternative drug therapy in arthritis. J. Assoc. Physic. Ind. 50: 225-227, 2002.
9. Chitme, H.R. and N.P. Patel. Antiarthritis activity of Aristolochia bracteata extract in experimental animals. Open Nat. Prod. J. 2: 6-15, 2009.
10. Chung, J.I., S. Barua, B.H. Choi, B.H. Min, H.C. Han and E.J. Baik. Anti-inflammatory effect of low intensity ultrasound (LIUS) on complete Freund's adjuvant-induced arthritis synovium. Osteoarthr. Cartil. 20: 314-322, 2012.
11. Crofford, L.J., R.L. Wilder, A.P. Ristimaki, H. Sano, E.F. Remmers, H.R. Epps and T. Hla. Cyclooxygenase-1 and-2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J. Clin. Invest. 93: 1095-1101, 1994.
12. Cuzzocrea, S., E. Mazzon, C. Bevilaqua, G. Costantino, D. Britti, G. Mazzullo, A. De Sarro and A.P. Caputi. Cloricromene, a coumarine derivative, protects against collagen-induced arthritis in Lewis rats. Br. J. Pharmacol. 131: 1399-1407, 2000.
13. Davies, N.M. and F. Jamali. COX-2 selective inhibitors cardiac toxicity: Getting to the heart of the matter. J. Pharm. Sci. 7: 332-336, 2004.
14. Fleischmann, R., R. Stern and I. Iqbal. Anakinra: An inhibitor of IL-1 for the treatment of rheumatoid arthritis. Exp. Opin. Biol. Ther. 4: 1333-1344, 2004.
15. Gerlag, D.M., L. Ransone, P.P. Tak, Z. Han, M. Palanki, M.S. Barbosa, D. Boyle, A.M. Manning and G.S. Firestein. Effect of a T cell specific NF-B inhibitor on in vitro cytokine production and collagen-induced arthritis. J. Immunol. 165: 1652-1658, 2000. (Pubitemid 30604604)
16. Goel, V., C. Chang, J.V. Slama, R. Barton, R. Bauer, R. Gahler and T.K. Basu. Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal rats. Int. Immunopharmacol. 2: 381-387, 2002.
17. Han, Z., D.L. Boyle, A.M. Manning and G.S. Firestein. AP-1 and NF-kappa B regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 28: 197-208, 1998. (Pubitemid 29027651)
18. Harris, S.G., J. Padilla, L. Koumas, D. Ray and R.P. Phipps. Prostaglandins as modulators of immunity. Trends Immunol. 23: 144-150, 2002. (Pubitemid 34178297)
19. Hou, C.W., Y.C. Lee, H.F. Hung, H.W. Fu and K.C. Jeng. Longan seed extract reduces hyperuricemia via modulating urate transporters and suppressing xanthine oxidase activity. Am. J. Chin. Med. 40: 979-991, 2012.
20. Jiang, L., F. Hu, Y. Tai, X. Yang, D. Yu, D. Li and Y. Yuan. Study on the extraction process and tyrosinase inhibition property of cichoric acid in Echinacea purpurea L. J. Medic. Plants Res. 6: 5317-5321, 2012.
21. Lin, Z., N. Neamati, H. Zhao, Y. Kiryu, J.A. Turpin, C. Aberham, K. Strebel, K. Kohn, M. Wityrouw, C. Pannecouque, Z. Debyser, E. De, Clercq, W.G. Rice, Y. Pommier and R.T. Burke. Cichoric acid analogues as HIV-1 integrase inhibitors. J. Med. Chem. 42: 1401-1414, 1999.
22. Manzo, A., M. Bombardieri, F. Humby and C. Pitzalis. Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: From inflammation to autoimmunity and tissue damage/ remodeling. Immunol. Rev. 233: 267-285, 2010.
23. Miagkov, A.V., D.V. Kovalenko, C.E. Brown, J.R. Didsbury, J.P. Cogswell, S.A. Stimpson, A.S. Baldwin and S.S. Makarov. NF-kappa B activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc. Natl. Acad. Sci. USA 95: 13859-13864, 1998.
24. Neugebauer, V., J.S. Han, H. Adwanikar, Y. Fu and G. Ji. Techniques for assessing knee joint pain in arthritis. Mol. Pain. 3: 8, 2007.
25. Newton, R.C. and C.P. Decicco. Therapeutic potential and strategies for inhibiting tumor necrosis factor-Alpha. J. Med. Chem. 42: 2295-2314, 1999.
26. Niki, Y., H. Yamada, T. Kikuchi, Y. Toyama, H. Matsumoto, K. Fujikawa and N. Tada. Membraneassociated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice. J. Immunol. 172: 577-584, 2004. (Pubitemid 38020515)
27. Paul, P.T. and S.F. Gary. NF-B: A key role in inflammatory diseases. J. Clin. Invest. 107: 7-11, 2001.
28. Scheiman, J.M. The impact of nonsteroidal anti-inflammatory drug-induced gastropathy. Am. J. Manag. Care 7: S10, 2001.
29. Shah, S.U., N. Ashraf, Z.H. Soomro, M.R. Shah, N. Kabir and S.U. Simjee. The anti-Arthritic and anti-oxidative effect of NBD (6-nitro-1, 3-benzodioxane) in adjuvant-induced arthritis (AIA) in rats. Inflamm. Res. 61: 875-887, 2012.
30. Sharma, S.M., M. Anderson, S.R. Schoop and J.B. Hudson. Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (EchinaforceR): Dual actions against respiratory bacteria. Phytomedicine 17: 563-568, 2010.
31. Stimpel, M., A. Proksch, H. Wagner and M.L. Lohmann-Matthes. Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea. Infect. Immun. 46: 845-849, 1984.
32. Suresh, P., C.N. Kavitha, S.M. Babu, V.P. Reddy and A.K. Latha. Effect of ethanol extract of Trigonella foenum graecum (Fenugreek) seeds on Freund's adjuvant-induced arthritis in albino rats. Inflammation 35: 1314-1321, 2012.
33. Tak, P.P. and G.S. Firestein. IkB kinase-2 (IKK-2) is a key regulator of synovial inflammation. Arthritis Rheum. 42: S400, 1999.
34. Takagi, T., P.W. Tsao, R. Totsuka, T. Suzuki, T. Murata and I. Takata. Dex amethasone prevents the decrease of bone mineral density in type II collagen-induced rat arthritis model. Jpn. J. Pharmacol. 78: 225-228, 1998.
35. Walz, D.T., M.J. DiMartino and A. Misher. Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters. J. Pharmacol. Exp. Ther. 178: 223-231, 1971.
36. Wei, Y.H., Y. Li and C.J. Qiang. Effects and mechanisms of FR167653, a dual inhibitor of interleukin-1 and tumor necrosis factor, on adjuvant arthritis in rats. Int. Immunopharmacol. 4: 1625-1632, 2004.
37. Wittenberg, R.H., R.E. Willburger, K.S. Kleemeyer and B.A. Peskar. In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases. Arthritis Rheum. 36: 1444-1450, 1993.
38. Xu, W., K. Chu, H. Li, Y. Zhang, M. Huang, H. Zheng, M. Sha, X. Zhang and L. Chen. Bauhinia championii extraction treatment of collagen-induced arthritis via down regulation of the expression of TLR4, MyD88 and NF-B. Am. J. Chin. Med. 41: 379-390, 2013.
39. Yamada, A.N., R. Grespan, A.T. Yamada, E.L. Silva, S.E. Silva-Filho, M.J. Damiao, M.M. de Oliveira Dalalio, C.A. Bersani-Amado and R.K. Cuman. Anti-inflammatory activity of Ocimum americanum L. essential oil in experimental model of zymosan-induced arthritis. Am. J. Chin. Med. 41: 913-926, 2013.
40. Yang, Q., G.Z. Yang, L. Wang and Y.Q. Ma. Effects of Tripterygium wilfordii Hook F in adjuvant arthritis rats model. Sichuan J. Anat. 14: 11-13, 2006.
41. Zhang, R.X., A.Y. Fan, A.N. Zhou, K.D. Moudgil, Z.Z. Ma, D.Y.W. Lee, H.H. Fong, B.M. Berman and L. Lao. Extract of the Chinese herbal formula Huo Luo Xiao Ling Dan inhibited adjuvant arthritis in rats. J. Ethnopharmacol. 121: 366-371, 2009.
42. Zhang, X., L. Rizshsky, C. Hauck, L. Qu, M.P. Widrlechner, B.J. Nikolau, P.A. Murphy and D.F. Birt. Bauer ketones 23 and 24 from Echinacea paradoxa var. paradoxa inhibit lipopolysaccharide-induced nitric oxide, prostaglandin E2 and cytokines in RAW264.7 mouse macrophages. Phytochemistry 74: 146-158, 2012.
43. Zhao, W., T. Tong, L. Wang, P.P. Li, Y. Chang, L.L. Zhang and W. Wei. Chicken type II collagen induced immune tolerance of mesenteric lymph node lymphocytes by enhancing beta2-Adrenergic receptor desensitization in rats with collagen-induced arthritis. Int. Immunopharmacol. 11: 12-18, 2011.
44. Zhou, X.F., X.Y. Zhao, L. Tang, Y.H. Zhang, H.L. Ruan, H.F. Pi, J. Qiu and J.Z. Wu. Immunomodulatory activity of the rhizomes of Impatiens pritzellii var. hupehensis on collagen-induced arthritis mice. J. Ethnopharmacol. 109: 505-509, 2007. (Pubitemid 46054383)