Validation and reproducibility assessment of modality independent elastography in a pre-clinical model of breast cancer

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 9038, Issue , 2014, Pages

  Weis, Jared A ^a,b   Kim, Dong K ^c   Yankeelov, Thomas E ^a,b,c   Miga, Michael I ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Breast cancer; Elastography; Mechanical model; Mechanical properties; Parameter reconstruction

Indexed keywords

BIOMARKERS; ELASTICITY; MECHANICAL PROPERTIES; MEDICAL APPLICATIONS; MOLECULAR IMAGING; STIFFNESS;

BREAST CANCER; ELASTOGRAPHY; EXTRACELLULAR MATRIX REMODELING; MECHANICAL MODEL; MECHANICAL STIFFNESS; PARAMETER RECONSTRUCTION; STATISTICAL DIFFERENCES; THERAPEUTIC MONITORING;

DISEASES;

EID: 84901768340     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.2042796     Document Type: Conference Paper

References (26)

1. Weis, J. A., Yankeelov, T. E., Munoz, S. A., Sastry, R. A., Barnes, S. L., Arlinghaus, L. R., Li, X., and I., M. M. "A consistent pre-clinical/clinical elastography approach for assessing tumor mechanical properties in therapeutic systems," SPIE 2013 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging (2013).
2. Paszek, M. J. and Weaver, V. M., "The tension mounts: mechanics meets morphogenesis and malignancy," J Mammary Gland Biol Neoplasia, vol. 9(4), p. 325-42 (2004).
3. Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., Hammer, D. A., and Weaver, V. M., "Tensional homeostasis and the malignant phenotype," Cancer Cell, vol. 8(3), p. 241-54 (2005).
4. Paszek, M. J., Zahir, N., Lakins, J. N., Johnson, K., Rozenberg, G., Dembo, M., Hammer, D. A., and Weaver, V. M., "Mechano-signaling in mammary morphogenesis and tumorigenesis," Molecular Biology of the Cell, vol. 15p. 241a-241a (2004).
5. Huang, S. and Ingber, D. E., "Cell tension, matrix mechanics, and cancer development," Cancer Cell, vol. 8(3), p. 175-176 (2005).
6. Shieh, A. C., "Biomechanical forces shape the tumor microenvironment," Ann Biomed Eng, vol. 39(5), p. 1379-89 (2011).
7. Engler, A. J., Berry, M., Sweeney, H. L., and Discher, D. E., "Substrate compliance alters human mesenchymal stem cell morphology," Molecular Biology of the Cell, vol. 15p. 298a-298a (2004).
8. Engler, A. J., Feng, H., Sweeney, H. L., and Discher, D. E., "Cells on gels: Skeletal muscle cell differentiation and adhesion on flexible substrates," Molecular Biology of the Cell, vol. 13p. 63a-63a (2002).
9. Engler, A. J., Berry, M., Sweeney, H. L., and Discher, D. E., "Substrate elasticity directs adult mesenchymal stem cell differentiation," Biorheology, vol. 42(1-2), p. 33-33 (2005).
10. Lo, C. M., Wang, H. B., Dembo, M., and Wang, Y. L., "Cell movement is guided by the rigidity of the substrate," Biophysical Journal, vol. 79(1), p. 144-152 (2000).
11. Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W. Y., Weaver, V., and Janmey, P. A., "Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion," Cell Motility and the Cytoskeleton, vol. 60(1), p. 24-34 (2005).
12. Helmlinger, G., Netti, P. A., Lichtenbeld, H. C., Melder, R. J., and Jain, R. K., "Solid stress inhibits the growth of multicellular tumor spheroids," Nature Biotechnology, vol. 15(8), p. 778-783 (1997).
13. Stein, A. M., Demuth, T., Mobley, D., Berens, M., and Sander, L. M., "A mathematical model of glioblastoma tumor spheroid invasion in a three-dimensional in vitro experiment," Biophysical Journal, vol. 92(1), p. 356-365 (2007).
14. Cheng, G., Tse, J., Jain, R. K., and Munn, L. L., "Micro- environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells," PLoS One, vol. 4(2), p. e4632 (2009).
15. Burridge, K. and Doughman, R., "Front and back by Rho and Rac," Nat Cell Biol, vol. 8(8), p. 781-2 (2006).
16. Roovers, K. and Assoian, R. K., "Effects of rho kinase and actin stress fibers on sustained extracellular signalregulated kinase activity and activation of G(1) phase cyclin-dependent kinases," Mol Cell Biol, vol. 23(12), p. 4283-94 (2003).
17. Thirion, J. P., "Image matching as a diffusion process: an analogy with Maxwell's demons," Med Image Anal, vol. 2(3), p. 243-60 (1998).
18. Polak, E. and Ribiere, G., "Note surla convergence des méthodes de directions conjuguées," Rev. Fr. Imform. Rech. Oper., vol. 16p. 35-43 (1969).
19. Oberai, A. A., Gokhale, N. H., and Feijoo, G. R., "Solution of inverse problems in elasticity imaging using the adjoint method," Inverse Problems, vol. 19p. 297-313 (2003).
20. Ou, J. J., Ong, R. E., Yankeelov, T. E., and Miga, M. I., "Evaluation of 3D modality-independent elastography for breast imaging: a simulation study," Physics in Medicine and Biology, vol. 53(1), p. 147-163 (2008).
21. Pheiffer, T. S., Ou, J. J., Ong, R. E., and Miga, M. I., "Automatic Generation of Boundary Conditions Using Demons Nonrigid Image Registration for Use in 3-D Modality-Independent Elastography," Ieee Transactions on Biomedical Engineering, vol. 58(9), p. 2607-2616 (2011).
22. McGarry, M., Johnson, C. L., Sutton, B. P., Van Houten, E. E., Georgiadis, J. G., Weaver, J. B., and Paulsen, K. D., "Including spatial information in nonlinear inversion MR elastography using soft prior regularization," IEEE Trans Med Imaging, vol. 32(10), p. 1901-9 (2013).
23. Miga, M. I., "A new approach to elastographic imaging: Modality independent elastography," Medical Imaging 2002: Image Processing: Proc. of the SPIE, vol. 4684p. 604-611 (2002).
24. Miga, M. I., "A new approach to elastography using mutual information and finite elements," Phys Med Biol, vol. 48(4), p. 467-80 (2003).
25. Miga, M. I., Rothney, M. P., and Ou, J. J., "Modality independent elastography (MIE): Potential applications in dermoscopy," Medical Physics, vol. 32(5), p. 1308-1320 (2005).
26. Washington, C. W. and Miga, M. I., "Modality independent elastography (MIE): A new approach to elasticity imaging," Ieee Transactions on Medical Imaging, vol. 23(9), p. 1117-1128 (2004).