Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size

Nature Communications

Volumn 5, Issue , 2014, Pages

  Chen, Jian Fu ^a,b   Zhang, Ying ^a   Wilde, Jonathan ^a   Hansen, Kirk C ^c   Lai, Fan ^d   Niswander, Lee ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Department of Genetics Department of Biochemistry and Molecular Biology University of Georgia ^*  (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; AURKA PROTEIN, MOUSE; CELL CYCLE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; WDR62 PROTEIN, MOUSE;

ABNORMALITY; BRAIN; GENE EXPRESSION; GENETIC ENGINEERING; HUMAN ACTIVITY; NERVOUS SYSTEM DISORDER; NUMERICAL MODEL; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SIZE; CELL DEATH; CONTROLLED STUDY; DWARFISM; GENE MUTATION; M PHASE CELL CYCLE CHECKPOINT; MICROCEPHALY; MITOSIS; MITOSIS INHIBITION; MOUSE; NEURAL STEM CELL; NEWBORN; NONHUMAN; ANIMAL; BRAIN; EMBRYOLOGY; EMBRYONIC STEM CELL; GENETICS; METABOLISM; MUTATION; ORGAN SIZE; PATHOLOGY; SPINDLE APPARATUS;

ANIMALS; AURORA KINASE A; BRAIN; CELL CYCLE PROTEINS; EMBRYONIC STEM CELLS; M PHASE CELL CYCLE CHECKPOINTS; MICE; MICROCEPHALY; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MUTATION; NEURAL STEM CELLS; ORGAN SIZE; SPINDLE APPARATUS;

EID: 84901765986     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4885     Document Type: Article

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